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Items: 41


Publisher Correction: Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer.

Ngô HM, Zhou Y, Lorenzi H, Wang K, Kim TK, Zhou Y, El Bissati K, Mui E, Fraczek L, Rajagopala SV, Roberts CW, Henriquez FL, Montpetit A, Blackwell JM, Jamieson SE, Wheeler K, Begeman IJ, Naranjo-Galvis C, Alliey-Rodriguez N, Davis RG, Soroceanu L, Cobbs C, Steindler DA, Boyer K, Noble AG, Swisher CN, Heydemann PT, Rabiah P, Withers S, Soteropoulos P, Hood L, McLeod R.

Sci Rep. 2019 May 28;9(1):8110. doi: 10.1038/s41598-019-44545-0.


The legacy of industrial pollution in estuarine sediments: spatial and temporal variability implications for ecosystem stress.

Rodgers K, McLellan I, Peshkur T, Williams R, Tonner R, Knapp CW, Henriquez FL, Hursthouse AS.

Environ Geochem Health. 2019 May 22. doi: 10.1007/s10653-019-00316-4. [Epub ahead of print]


Acanthamoeba proteases contribute to macrophage activation through PAR1 , but not PAR2.

Cano A, Mattana A, Henriquez FL, Alexander J, Roberts CW.

Parasite Immunol. 2019 Feb;41(2):e12612. doi: 10.1111/pim.12612.


Alopecia areata: A multifactorial autoimmune condition.

Simakou T, Butcher JP, Reid S, Henriquez FL.

J Autoimmun. 2019 Mar;98:74-85. doi: 10.1016/j.jaut.2018.12.001. Epub 2018 Dec 15. Review.


Variability in nitrate-reducing oral bacteria and nitric oxide metabolites in biological fluids following dietary nitrate administration: An assessment of the critical difference.

Liddle L, Burleigh MC, Monaghan C, Muggeridge DJ, Sculthorpe N, Pedlar CR, Butcher J, Henriquez FL, Easton C.

Nitric Oxide. 2019 Feb 1;83:1-10. doi: 10.1016/j.niox.2018.12.003. Epub 2018 Dec 5.


Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials.

Rice CA, Campbell SJ, Bisson C, Owen HJ, Sedelnikova SE, Baker PJ, Rice DW, Henriquez FL, Roberts CW.

PLoS One. 2018 Jul 3;13(7):e0198827. doi: 10.1371/journal.pone.0198827. eCollection 2018.


Control of cell behaviour through nanovibrational stimulation: nanokicking.

Robertson SN, Campsie P, Childs PG, Madsen F, Donnelly H, Henriquez FL, Mackay WG, Salmerón-Sánchez M, Tsimbouri MP, Williams C, Dalby MJ, Reid S.

Philos Trans A Math Phys Eng Sci. 2018 May 28;376(2120). pii: 20170290. doi: 10.1098/rsta.2017.0290. Review.


Salivary nitrite production is elevated in individuals with a higher abundance of oral nitrate-reducing bacteria.

Burleigh MC, Liddle L, Monaghan C, Muggeridge DJ, Sculthorpe N, Butcher JP, Henriquez FL, Allen JD, Easton C.

Free Radic Biol Med. 2018 May 20;120:80-88. doi: 10.1016/j.freeradbiomed.2018.03.023. Epub 2018 Mar 14.


Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer.

Ngô HM, Zhou Y, Lorenzi H, Wang K, Kim TK, Zhou Y, El Bissati K, Mui E, Fraczek L, Rajagopala SV, Roberts CW, Henriquez FL, Montpetit A, Blackwell JM, Jamieson SE, Wheeler K, Begeman IJ, Naranjo-Galvis C, Alliey-Rodriguez N, Davis RG, Soroceanu L, Cobbs C, Steindler DA, Boyer K, Noble AG, Swisher CN, Heydemann PT, Rabiah P, Withers S, Soteropoulos P, Hood L, McLeod R.

Sci Rep. 2017 Sep 13;7(1):11496. doi: 10.1038/s41598-017-10675-6. Erratum in: Sci Rep. 2019 May 28;9(1):8110.


Characterisation of sterol biosynthesis and validation of 14α-demethylase as a drug target in Acanthamoeba.

Thomson S, Rice CA, Zhang T, Edrada-Ebel R, Henriquez FL, Roberts CW.

Sci Rep. 2017 Aug 15;7(1):8247. doi: 10.1038/s41598-017-07495-z.


Acanthamoeba Activates Macrophages Predominantly through Toll-Like Receptor 4- and MyD88-Dependent Mechanisms To Induce Interleukin-12 (IL-12) and IL-6.

Cano A, Mattana A, Woods S, Henriquez FL, Alexander J, Roberts CW.

Infect Immun. 2017 May 23;85(6). pii: e01054-16. doi: 10.1128/IAI.01054-16. Print 2017 Jun.


The role of chemokines and their receptors during protist parasite infections.

Menzies FM, Macphail D, Henriquez FL.

Parasitology. 2016 Dec;143(14):1890-1901. Epub 2016 Oct 6. Review.


Acanthamoeba castellanii Genotype T4 Stimulates the Production of Interleukin-10 as Well as Proinflammatory Cytokines in THP-1 Cells, Human Peripheral Blood Mononuclear Cells, and Human Monocyte-Derived Macrophages.

Mattana A, Sanna M, Cano A, Delogu G, Erre G, Roberts CW, Henriquez FL, Fiori PL, Cappuccinelli P.

Infect Immun. 2016 Sep 19;84(10):2953-62. doi: 10.1128/IAI.00345-16. Print 2016 Oct.


Use of nanoscale mechanical stimulation for control and manipulation of cell behaviour.

Childs PG, Boyle CA, Pemberton GD, Nikukar H, Curtis ASG, Henriquez FL, Dalby MJ, Reid S.

Acta Biomater. 2016 Apr 1;34:159-168. doi: 10.1016/j.actbio.2015.11.045. Epub 2015 Dec 2. Review.


The Acanthamoeba shikimate pathway has a unique molecular arrangement and is essential for aromatic amino acid biosynthesis.

Henriquez FL, Campbell SJ, Sundararaj BK, Cano A, Muench SP, Roberts CW.

Protist. 2015 Feb;166(1):93-105. doi: 10.1016/j.protis.2014.12.001. Epub 2014 Dec 11.


Complex patterns of gene fission in the eukaryotic folate biosynthesis pathway.

Maguire F, Henriquez FL, Leonard G, Dacks JB, Brown MW, Richards TA.

Genome Biol Evol. 2014 Sep 23;6(10):2709-20. doi: 10.1093/gbe/evu213.


Biochemical and immunological characterization of Toxoplasma gondii macrophage migration inhibitory factor.

Sommerville C, Richardson JM, Williams RA, Mottram JC, Roberts CW, Alexander J, Henriquez FL.

J Biol Chem. 2013 May 3;288(18):12733-41. doi: 10.1074/jbc.M112.419911. Epub 2013 Feb 26.


Comparative assessment of a DNA and protein Leishmania donovani gamma glutamyl cysteine synthetase vaccine to cross-protect against murine cutaneous leishmaniasis caused by L. major or L. mexicana infection.

Campbell SA, Alawa J, Doro B, Henriquez FL, Roberts CW, Nok A, Alawa CB, Alsaadi M, Mullen AB, Carter KC.

Vaccine. 2012 Feb 8;30(7):1357-63. doi: 10.1016/j.vaccine.2011.12.067. Epub 2011 Dec 28.


Toxoplasma gondii HLA-B*0702-restricted GRA7(20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells producing interferon-γ and reduces parasite burden in HLA-B*0702 mice.

Cong H, Mui EJ, Witola WH, Sidney J, Alexander J, Sette A, Maewal A, El Bissati K, Zhou Y, Suzuki Y, Lee D, Woods S, Sommerville C, Henriquez FL, Roberts CW, McLeod R.

Hum Immunol. 2012 Jan;73(1):1-10. doi: 10.1016/j.humimm.2011.10.006. Epub 2011 Oct 12.


Selective inhibition and augmentation of alternative macrophage activation by progesterone.

Menzies FM, Henriquez FL, Alexander J, Roberts CW.

Immunology. 2011 Nov;134(3):281-91. doi: 10.1111/j.1365-2567.2011.03488.x.


Vaccination with recombinant Leishmania donovani gamma-glutamylcysteine synthetase fusion protein protects against L. donovani infection.

Henriquez FL, Campbell SA, Roberts CW, Mullen AB, Burchmore R, Carter KC.

J Parasitol. 2010 Oct;96(5):929-36. doi: 10.1645/GE-2360.1. Epub 2010 Apr 17.


Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase.

Tipparaju SK, Muench SP, Mui EJ, Ruzheinikov SN, Lu JZ, Hutson SL, Kirisits MJ, Prigge ST, Roberts CW, Henriquez FL, Kozikowski AP, Rice DW, McLeod RL.

J Med Chem. 2010 Sep 9;53(17):6287-300. doi: 10.1021/jm9017724.


Immunogenetics of Toxoplasma gondii informs vaccine design.

Henriquez FL, Woods S, Cong H, McLeod R, Roberts CW.

Trends Parasitol. 2010 Nov;26(11):550-5. doi: 10.1016/ Epub 2010 Jun 26. Review.


Sequential expression of macrophage anti-microbial/inflammatory and wound healing markers following innate, alternative and classical activation.

Menzies FM, Henriquez FL, Alexander J, Roberts CW.

Clin Exp Immunol. 2010 Jun;160(3):369-79. doi: 10.1111/j.1365-2249.2009.04086.x. Epub 2010 Jan 5.


Drug target identification, validation, characterisation and exploitation for treatment of Acanthamoeba (species) infections.

Roberts CW, Henriquez FL.

Exp Parasitol. 2010 Sep;126(1):91-6. doi: 10.1016/j.exppara.2009.11.016. Epub 2009 Dec 24. Review.


IL-33 receptor (T1/ST2) signalling is necessary to prevent the development of encephalitis in mice infected with Toxoplasma gondii.

Jones LA, Roberts F, Nickdel MB, Brombacher F, McKenzie AN, Henriquez FL, Alexander J, Roberts CW.

Eur J Immunol. 2010 Feb;40(2):426-36. doi: 10.1002/eji.200939705.


Acanthamoeba alternative oxidase genes: identification, characterisation and potential as antimicrobial targets.

Henriquez FL, McBride J, Campbell SJ, Ramos T, Ingram PR, Roberts F, Tinney S, Roberts CW.

Int J Parasitol. 2009 Nov;39(13):1417-24. doi: 10.1016/j.ijpara.2009.04.011. Epub 2009 May 21.


The Toxoplasma gondii plastid replication and repair enzyme complex, PREX.

Mukhopadhyay A, Chen CY, Doerig C, Henriquez FL, Roberts CW, Barrett MP.

Parasitology. 2009 Jun;136(7):747-55. doi: 10.1017/S0031182009006027. Epub 2009 Apr 30.


The T1799A point mutation is present in posterior uveal melanoma.

Janssen CS, Sibbett R, Henriquez FL, McKay IC, Kemp EG, Roberts F.

Br J Cancer. 2008 Nov 18;99(10):1673-7. doi: 10.1038/sj.bjc.6604731. Epub 2008 Nov 4.


Induced encystment improves resistance to preservation and storage of Acanthamoeba castellanii.

Campbell SJ, Ingram PR, Roberts CW, Henriquez FL.

Parasitology. 2008 Oct;135(12):1401-5. doi: 10.1017/S0031182008005003.


Toll-like receptor-4-mediated macrophage activation is differentially regulated by progesterone via the glucocorticoid and progesterone receptors.

Jones LA, Anthony JP, Henriquez FL, Lyons RE, Nickdel MB, Carter KC, Alexander J, Roberts CW.

Immunology. 2008 Sep;125(1):59-69. doi: 10.1111/j.1365-2567.2008.02820.x. Epub 2008 Mar 28.


Molecular basis for resistance of acanthamoeba tubulins to all major classes of antitubulin compounds.

Henriquez FL, Ingram PR, Muench SP, Rice DW, Roberts CW.

Antimicrob Agents Chemother. 2008 Mar;52(3):1133-5. Epub 2007 Dec 10.


Immunological control of congenital toxoplasmosis in the murine model.

Menzies FM, Henriquez FL, Roberts CW.

Immunol Lett. 2008 Jan 29;115(2):83-9. Epub 2007 Nov 6. Review.


DNA vaccination against the parasite enzyme gamma-glutamylcysteine synthetase confers protection against Leishmania donovani infection.

Carter KC, Henriquez FL, Campbell SA, Roberts CW, Nok A, Mullen AB, McFarlane E.

Vaccine. 2007 May 30;25(22):4502-9. Epub 2007 Mar 26.


Enzymes of type II fatty acid synthesis and apicoplast differentiation and division in Eimeria tenella.

Ferguson DJ, Campbell SA, Henriquez FL, Phan L, Mui E, Richards TA, Muench SP, Allary M, Lu JZ, Prigge ST, Tomley F, Shirley MW, Rice DW, McLeod R, Roberts CW.

Int J Parasitol. 2007 Jan;37(1):33-51. Epub 2006 Oct 30.


Resistance of Leishmania donovani to sodium stibogluconate is related to the expression of host and parasite gamma-glutamylcysteine synthetase.

Carter KC, Hutchison S, Henriquez FL, Légaré D, Ouellette M, Roberts CW, Mullen AB.

Antimicrob Agents Chemother. 2006 Jan;50(1):88-95.


Toxoplasma gondii dense granule protein 3 (GRA3) is a type I transmembrane protein that possesses a cytoplasmic dilysine (KKXX) endoplasmic reticulum (ER) retrieval motif.

Henriquez FL, Nickdel MB, McLeod R, Lyons RE, Lyons K, Dubremetz JF, Grigg ME, Samuel BU, Roberts CW.

Parasitology. 2005 Aug;131(Pt 2):169-79.


Maternal inheritance and stage-specific variation of the apicoplast in Toxoplasma gondii during development in the intermediate and definitive host.

Ferguson DJ, Henriquez FL, Kirisits MJ, Muench SP, Prigge ST, Rice DW, Roberts CW, McLeod RL.

Eukaryot Cell. 2005 Apr;4(4):814-26.


Development of colorimetric microtiter plate assay for assessment of antimicrobials against Acanthamoeba.

McBride J, Ingram PR, Henriquez FL, Roberts CW.

J Clin Microbiol. 2005 Feb;43(2):629-34.


The unusual mitochondrial compartment of Cryptosporidium parvum.

Henriquez FL, Richards TA, Roberts F, McLeod R, Roberts CW.

Trends Parasitol. 2005 Feb;21(2):68-74. Review.


Evidence for mitochondrial-derived alternative oxidase in the apicomplexan parasite Cryptosporidium parvum: a potential anti-microbial agent target.

Roberts CW, Roberts F, Henriquez FL, Akiyoshi D, Samuel BU, Richards TA, Milhous W, Kyle D, McIntosh L, Hill GC, Chaudhuri M, Tzipori S, McLeod R.

Int J Parasitol. 2004 Mar 9;34(3):297-308.


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