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Items: 1 to 50 of 244

1.

The Critical Role of Hypoxic Microenvironment and Epigenetic Deregulation in Esophageal Cancer Radioresistance.

Macedo-Silva C, Miranda-Gonçalves V, Henrique R, Jerónimo C, Bravo I.

Genes (Basel). 2019 Nov 14;10(11). pii: E927. doi: 10.3390/genes10110927. Review.

2.

Detailed Characterization of Immune Cell Infiltrate and Expression of Immune Checkpoint Molecules PD-L1/CTLA-4 and MMR Proteins in Testicular Germ Cell Tumors Disclose Novel Disease Biomarkers.

Lobo J, Rodrigues Â, Guimarães R, Cantante M, Lopes P, Maurício J, Oliveira J, Jerónimo C, Henrique R.

Cancers (Basel). 2019 Oct 11;11(10). pii: E1535. doi: 10.3390/cancers11101535.

3.

Identification of a biomarker panel for improvement of prostate cancer diagnosis by volatile metabolic profiling of urine.

Lima AR, Pinto J, Azevedo AI, Barros-Silva D, Jerónimo C, Henrique R, de Lourdes Bastos M, Guedes de Pinho P, Carvalho M.

Br J Cancer. 2019 Nov;121(10):857-868. doi: 10.1038/s41416-019-0585-4. Epub 2019 Oct 7.

PMID:
31588123
4.

A Rare Case of Renal AA Amyloidosis Secondary to Sjogren's Syndrome.

Costa M, Greenfield H, Pereira R, Chuva T, Henrique R, Cunha C.

Eur J Case Rep Intern Med. 2019 Sep 16;6(9):001226. doi: 10.12890/2019_001226. eCollection 2019.

5.

Circulating MicroRNAs as Biomarkers for Prostate Cancer Detection and Metastasis Development Prediction.

Bidarra D, Constâncio V, Barros-Silva D, Ramalho-Carvalho J, Moreira-Barbosa C, Antunes L, Maurício J, Oliveira J, Henrique R, Jerónimo C.

Front Oncol. 2019 Sep 11;9:900. doi: 10.3389/fonc.2019.00900. eCollection 2019.

6.

Predictive and Prognostic Value of Selected MicroRNAs in Luminal Breast Cancer.

Amorim M, Lobo J, Fontes-Sousa M, Estevão-Pereira H, Salta S, Lopes P, Coimbra N, Antunes L, Palma de Sousa S, Henrique R, Jerónimo C.

Front Genet. 2019 Sep 11;10:815. doi: 10.3389/fgene.2019.00815. eCollection 2019.

7.

Subtyping Lung Cancer Using DNA Methylation in Liquid Biopsies.

Nunes SP, Diniz F, Moreira-Barbosa C, Constâncio V, Silva AV, Oliveira J, Soares M, Paulino S, Cunha AL, Rodrigues J, Antunes L, Henrique R, Jerónimo C.

J Clin Med. 2019 Sep 19;8(9). pii: E1500. doi: 10.3390/jcm8091500.

8.

Corrigendum: Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets.

Miranda-Gonçalves V, Lameirinhas A, Henrique R, Jerónimo C.

Front Genet. 2019 Sep 13;10:784. doi: 10.3389/fgene.2019.00784. eCollection 2019.

9.

Disseminated Well-Differentiated Gastro-Entero-Pancreatic Tumors Are Associated with Metabolic Syndrome.

Santos AP, Castro C, Antunes L, Henrique R, Cardoso MH, Monteiro MP.

J Clin Med. 2019 Sep 17;8(9). pii: E1479. doi: 10.3390/jcm8091479.

10.

XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality.

Lobo J, Nunes SP, Gillis AJM, Barros-Silva D, Miranda-Gonçalves V, Berg AVD, Cantante M, Guimarães R, Henrique R, Jerónimo C, Looijenga LHJ.

Cancers (Basel). 2019 Sep 17;11(9). pii: E1385. doi: 10.3390/cancers11091385.

11.

Higher IL-6 peri-tumoural expression is associated with gastro-intestinal neuroendocrine tumour progression.

Pereira SS, Pereira R, Santos AP, Costa MM, Morais T, Sampaio P, Machado B, Afonso LP, Henrique R, Monteiro MP.

Pathology. 2019 Oct;51(6):593-599. doi: 10.1016/j.pathol.2019.07.001. Epub 2019 Aug 26.

PMID:
31466863
12.

Moving tissue spectral window to the deep-ultraviolet via optical clearing.

Carneiro I, Carvalho S, Henrique R, Oliveira L, Tuchin V.

J Biophotonics. 2019 Aug 29:e201900181. doi: 10.1002/jbio.201900181. [Epub ahead of print]

PMID:
31465137
13.

Widening the spectrum of Lynch syndrome: first report of testicular seminoma attributable to MSH2 loss.

Lobo J, Pinto C, Pinheiro M, Lobo F, Sousa N, Lopes P, Looijenga LH, Jerónimo C, Teixeira MR, Henrique R.

Histopathology. 2019 Aug 23. doi: 10.1111/his.13979. [Epub ahead of print] No abstract available.

PMID:
31442315
14.

High-Risk human papillomavirus genotype distribution in the Northern region of Portugal: Data from regional cervical cancer screening program.

Sousa H, Tavares A, Campos C, Marinho-Dias J, Brito M, Medeiros R, Baldaque I, Lobo C, Leça L, Monteiro P, Tavares F, Henrique R.

Papillomavirus Res. 2019 Aug 1;8:100179. doi: 10.1016/j.pvr.2019.100179. [Epub ahead of print]

15.

E-cadherin clone 36 nuclear staining dictates adverse disease outcome in lobular breast cancer patients.

Lobo J, Petronilho S, Newell AH, Coach J, Harlow G, Cruz A, Lopes P, Antunes L, Bai I, Walker E, Henrique R.

Mod Pathol. 2019 Nov;32(11):1574-1586. doi: 10.1038/s41379-019-0294-9. Epub 2019 Jun 23.

PMID:
31231125
16.

In-air production of 3D co-culture tumor spheroid hydrogels for expedited drug screening.

Antunes J, Gaspar VM, Ferreira L, Monteiro M, Henrique R, Jerónimo C, Mano JF.

Acta Biomater. 2019 Aug;94:392-409. doi: 10.1016/j.actbio.2019.06.012. Epub 2019 Jun 12.

PMID:
31200118
17.

Successful treatment of refractory chylous ascites due to follicular lymphoma with very low-dose radiotherapy.

Tavares M, Ramalheira S, Chacim S, Henrique R, Oliveira Â, Mariz JM.

Rep Pract Oncol Radiother. 2019 Jul-Aug;24(4):344-346. doi: 10.1016/j.rpor.2019.05.001. Epub 2019 Jun 2.

PMID:
31194016
18.

Histone variant MacroH2A1 is downregulated in prostate cancer and influences malignant cell phenotype.

Vieira-Silva TS, Monteiro-Reis S, Barros-Silva D, Ramalho-Carvalho J, Graça I, Carneiro I, Martins AT, Oliveira J, Antunes L, Hurtado-Bagès S, Buschbeck M, Henrique R, Jerónimo C.

Cancer Cell Int. 2019 Apr 29;19:112. doi: 10.1186/s12935-019-0835-9. eCollection 2019.

19.

Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer.

Avogbe PH, Manel A, Vian E, Durand G, Forey N, Voegele C, Zvereva M, Hosen MI, Meziani S, De Tilly B, Polo G, Lole O, Francois P, Delhomme TM, Carreira C, Monteiro-Reis S, Henrique R, Abedi-Ardekani B, Byrnes G, Foll M, Weiderpass E, McKay J, Jeronimo C, Scelo G, Le Calvez-Kelm F.

EBioMedicine. 2019 Jun;44:431-438. doi: 10.1016/j.ebiom.2019.05.004. Epub 2019 May 20.

20.

Are there gross motor coordination spurts during mid-childhood?

Dos Santos MAM, Baxter-Jones A, Reyes AC, Freitas D, Henrique RS, Chaves RN, Bustamante A, Tani G, Katzmarzyk PT, Maia J.

Am J Hum Biol. 2019 Jul;31(4):e23251. doi: 10.1002/ajhb.23251. Epub 2019 May 7.

PMID:
31063218
21.

The Complex Interplay between Metabolic Reprogramming and Epigenetic Alterations in Renal Cell Carcinoma.

Lameirinhas A, Miranda-Gonçalves V, Henrique R, Jerónimo C.

Genes (Basel). 2019 Apr 2;10(4). pii: E264. doi: 10.3390/genes10040264. Review.

22.

The nonsense mutation MSH2 c.2152C>T shows a founder effect in Portuguese Lynch syndrome families.

Pinheiro M, Francisco I, Pinto C, Peixoto A, Veiga I, Filipe B, Santos C, Maia S, Silva J, Pinto P, Santos R, Claro I, Lage P, Lopes P, Ferreira S, Rosa I, Fonseca R, Rodrigues P, Henrique R, Chaves P, Pereira AD, Brandão C, Albuquerque C, Teixeira MR.

Genes Chromosomes Cancer. 2019 Sep;58(9):657-664. doi: 10.1002/gcc.22759. Epub 2019 Apr 26.

PMID:
30968502
23.

Known epigenetic biomarkers for prostate cancer detection and management: exploring the potential of blood-based liquid biopsies.

Constâncio V, Barros-Silva D, Jerónimo C, Henrique R.

Expert Rev Mol Diagn. 2019 May;19(5):367-375. doi: 10.1080/14737159.2019.1604224. Epub 2019 Apr 14.

PMID:
30961397
24.

m6A RNA modification and its writer/reader VIRMA/YTHDF3 in testicular germ cell tumors: a role in seminoma phenotype maintenance.

Lobo J, Costa AL, Cantante M, Guimarães R, Lopes P, Antunes L, Braga I, Oliveira J, Pelizzola M, Henrique R, Jerónimo C.

J Transl Med. 2019 Mar 12;17(1):79. doi: 10.1186/s12967-019-1837-z.

25.

Volatile metabolomic signature of bladder cancer cell lines based on gas chromatography-mass spectrometry.

Rodrigues D, Pinto J, Araújo AM, Monteiro-Reis S, Jerónimo C, Henrique R, de Lourdes Bastos M, de Pinho PG, Carvalho M.

Metabolomics. 2018 Apr 17;14(5):62. doi: 10.1007/s11306-018-1361-9.

PMID:
30830384
26.

GC-MS Metabolomics Reveals Distinct Profiles of Low- and High-Grade Bladder Cancer Cultured Cells.

Rodrigues D, Pinto J, Araújo AM, Jerónimo C, Henrique R, Bastos ML, Guedes de Pinho P, Carvalho M.

Metabolites. 2019 Jan 18;9(1). pii: E18. doi: 10.3390/metabo9010018.

27.

Predicting resistance to endocrine therapy in breast cancer: It's time for epigenetic biomarkers (Review).

Fontes-Sousa M, Amorim M, Salta S, Palma De Sousa S, Henrique R, Jerónimo C.

Oncol Rep. 2019 Mar;41(3):1431-1438. doi: 10.3892/or.2019.6967. Epub 2019 Jan 11. Review.

PMID:
30664168
28.

Familial resemblance in gross motor coordination. The Peruvian Sibling Study on Growth and Health.

Valdívia AB, Henrique RS, Pereira S, Chaves RN, Tani G, Freitas D, Prista A, Stodden DF, Katzmarzyk PT, Hedeker D, Maia J.

Ann Hum Biol. 2018 Sep - Dec;45(6-8):463-469. doi: 10.1080/03014460.2019.1568549.

PMID:
30646775
29.

Epigenetic Mechanisms Influencing Epithelial to Mesenchymal Transition in Bladder Cancer.

Monteiro-Reis S, Lobo J, Henrique R, Jerónimo C.

Int J Mol Sci. 2019 Jan 13;20(2). pii: E297. doi: 10.3390/ijms20020297. Review.

30.

Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic.

Lobo J, Gillis AJM, Jerónimo C, Henrique R, Looijenga LHJ.

Int J Mol Sci. 2019 Jan 10;20(2). pii: E258. doi: 10.3390/ijms20020258. Review.

31.

A robust ex vivo method to evaluate the diffusion properties of agents in biological tissues.

Carneiro I, Carvalho S, Henrique R, Oliveira LM, Tuchin VV.

J Biophotonics. 2019 Apr;12(4):e201800333. doi: 10.1002/jbio.201800333. Epub 2019 Jan 10.

PMID:
30585430
32.

The Role of DNA/Histone Modifying Enzymes and Chromatin Remodeling Complexes in Testicular Germ Cell Tumors.

Lobo J, Henrique R, Jerónimo C.

Cancers (Basel). 2018 Dec 20;11(1). pii: E6. doi: 10.3390/cancers11010006. Review.

33.

Oncogenic potential of CHAF1A in gastric cancer: A novel link with Helicobacter pylori-driven carcinogenesis?

Camilo V, Henrique R.

EBioMedicine. 2018 Dec;38:3-4. doi: 10.1016/j.ebiom.2018.11.033. Epub 2018 Nov 25. No abstract available.

34.

MSH2 Expression and Resistance to Cisplatin in Muscle-invasive Bladder Cancer: A Mix of Progress and Challenges.

Henrique R, Nunes SP, Jerónimo C.

Eur Urol. 2019 Feb;75(2):251-252. doi: 10.1016/j.eururo.2018.11.014. Epub 2018 Nov 20. No abstract available.

PMID:
30470617
35.

Integrative epigenetic taxonomy of primary prostate cancer.

Stelloo S, Nevedomskaya E, Kim Y, Schuurman K, Valle-Encinas E, Lobo J, Krijgsman O, Peeper DS, Chang SL, Feng FY, Wessels LFA, Henrique R, Jerónimo C, Bergman AM, Zwart W.

Nat Commun. 2018 Nov 21;9(1):4900. doi: 10.1038/s41467-018-07270-2.

36.

The Emerging Role of Epitranscriptomics in Cancer: Focus on Urological Tumors.

Lobo J, Barros-Silva D, Henrique R, Jerónimo C.

Genes (Basel). 2018 Nov 13;9(11). pii: E552. doi: 10.3390/genes9110552. Review.

37.

DNA methylation profiling as a tool for testicular germ cell tumors subtyping.

Costa AL, Moreira-Barbosa C, Lobo J, Vilela-Salgueiro B, Cantante M, Guimarães R, Lopes P, Braga I, Oliveira J, Antunes L, Henrique R, Jerónimo C.

Epigenomics. 2018 Dec;10(12):1511-1523. doi: 10.2217/epi-2018-0034. Epub 2018 Nov 12.

PMID:
30418048
38.

A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA.

Salta S, P Nunes S, Fontes-Sousa M, Lopes P, Freitas M, Caldas M, Antunes L, Castro F, Antunes P, Palma de Sousa S, Henrique R, Jerónimo C.

J Clin Med. 2018 Nov 7;7(11). pii: E420. doi: 10.3390/jcm7110420.

39.

Interplay between sympathetic nervous system and inflammation in aseptic loosening of hip joint replacement.

Ribeiro-da-Silva M, Vasconcelos DM, Alencastre IS, Oliveira MJ, Linhares D, Neves N, Costa G, Henrique R, Lamghari M, Alves CJ.

Sci Rep. 2018 Oct 30;8(1):16044. doi: 10.1038/s41598-018-33360-8.

40.

Comparing diagnostic and prognostic performance of two-gene promoter methylation panels in tissue biopsies and urines of prostate cancer patients.

Moreira-Barbosa C, Barros-Silva D, Costa-Pinheiro P, Torres-Ferreira J, Constâncio V, Freitas R, Oliveira J, Antunes L, Henrique R, Jerónimo C.

Clin Epigenetics. 2018 Oct 29;10(1):132. doi: 10.1186/s13148-018-0564-2.

41.

Metabolism and Epigenetic Interplay in Cancer: Regulation and Putative Therapeutic Targets.

Miranda-Gonçalves V, Lameirinhas A, Henrique R, Jerónimo C.

Front Genet. 2018 Oct 9;9:427. doi: 10.3389/fgene.2018.00427. eCollection 2018. Review. Erratum in: Front Genet. 2019 Sep 13;10:784.

42.

Hybrid oncocytic/chromophobe renal cell tumor: An integrated genetic and epigenetic characterization of a case.

Pires-Luis A, Montezuma D, Vieira J, Ramalho-Carvalho J, Santos C, Teixeira M, Jerónimo C, Henrique R.

Exp Mol Pathol. 2018 Dec;105(3):352-356. doi: 10.1016/j.yexmp.2018.10.008. Epub 2018 Oct 18.

PMID:
30343009
43.

Cell-Free DNA Methylation of Selected Genes Allows for Early Detection of the Major Cancers in Women.

Nunes SP, Moreira-Barbosa C, Salta S, Palma de Sousa S, Pousa I, Oliveira J, Soares M, Rego L, Dias T, Rodrigues J, Antunes L, Henrique R, Jerónimo C.

Cancers (Basel). 2018 Sep 26;10(10). pii: E357. doi: 10.3390/cancers10100357.

44.

Post‑transplant lymphoproliferative disorder in hematopoietic stem cell transplant patients: A single center retrospective study between 2005 and 2012.

Marinho-Dias J, Lobo J, Henrique R, Baldaque I, Pinho-Vaz C, Regadas L, Branca R, Campilho F, Campos A Jr, Medeiros R, Sousa H.

Mol Med Rep. 2018 Nov;18(5):4650-4656. doi: 10.3892/mmr.2018.9433. Epub 2018 Sep 3.

PMID:
30221663
45.

Visceral Obesity and Metabolic Syndrome Are Associated with Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors.

Santos AP, Santos AC, Castro C, Raposo L, Pereira SS, Torres I, Henrique R, Cardoso H, Monteiro MP.

Cancers (Basel). 2018 Aug 27;10(9). pii: E293. doi: 10.3390/cancers10090293.

46.

Profiling DNA Methylation Based on Next-Generation Sequencing Approaches: New Insights and Clinical Applications.

Barros-Silva D, Marques CJ, Henrique R, Jerónimo C.

Genes (Basel). 2018 Aug 23;9(9). pii: E429. doi: 10.3390/genes9090429. Review.

47.

Prognostic value of histone marks H3K27me3 and H3K9me3 and modifying enzymes EZH2, SETDB1 and LSD-1 in colorectal cancer.

Carvalho S, Freitas M, Antunes L, Monteiro-Reis S, Vieira-Coimbra M, Tavares A, Paulino S, Videira JF, Jerónimo C, Henrique R.

J Cancer Res Clin Oncol. 2018 Nov;144(11):2127-2137. doi: 10.1007/s00432-018-2733-2. Epub 2018 Aug 13.

PMID:
30105513
48.

Quantitative Analysis of Seven New Prostate Cancer Biomarkers and the Potential Future of the 'Biomarker Laboratory'.

Cao K, Arthurs C, Atta-Ul A, Millar M, Beltran M, Neuhaus J, Horn LC, Henrique R, Ahmed A, Thrasivoulou C.

Diagnostics (Basel). 2018 Jul 27;8(3). pii: E49. doi: 10.3390/diagnostics8030049.

49.

Testicular germ cell tumors: revisiting a series in light of the new WHO classification and AJCC staging systems, focusing on challenges for pathologists.

Lobo J, Costa AL, Vilela-Salgueiro B, Rodrigues Â, Guimarães R, Cantante M, Lopes P, Antunes L, Jerónimo C, Henrique R.

Hum Pathol. 2018 Dec;82:113-124. doi: 10.1016/j.humpath.2018.07.016. Epub 2018 Jul 21.

PMID:
30041024
50.

Differential expression of E-cadherin and P-cadherin in pT3 prostate cancer: correlation with clinical and pathological features.

Ferreira C, Lobo J, Antunes L, Lopes P, Jerónimo C, Henrique R.

Virchows Arch. 2018 Oct;473(4):443-452. doi: 10.1007/s00428-018-2406-1. Epub 2018 Jul 13.

PMID:
30006753

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