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Addition of trans-fat and alcohol has divergent effects on atherogenic diet-induced liver injury in rodent models of steatohepatitis.

Daniels SJ, Leeming DJ, Detlefsen S, Bruun MF, Hjuler ST, Henriksen K, Hein P, Krag A, Karsdal MA, Nielsen MJ, Brockbank S, Cruwys S.

Am J Physiol Gastrointest Liver Physiol. 2020 Jan 6. doi: 10.1152/ajpgi.00066.2019. [Epub ahead of print]


A caspase-6-cleaved fragment of Glial Fibrillary Acidic Protein as a potential serological biomarker of CNS injury after cardiac arrest.

Jonesco DS, Hassager C, Frydland M, Kjærgaard J, Karsdal M, Henriksen K.

PLoS One. 2019 Nov 6;14(11):e0224633. doi: 10.1371/journal.pone.0224633. eCollection 2019.


Biochemical markers in osteoarthritis with lessons learned from osteoporosis.

Karsdal MA, Henriksen K, Bay-Jensen AC.

Clin Exp Rheumatol. 2019 Sep-Oct;37 Suppl 120(5):73-87. Epub 2019 Oct 15. Review.


An incidental but pathognomonic finding in renal allograft biopsy.

Sekar P, West BL, Henriksen KJ, Chang A.

Kidney Int. 2019 Oct;96(4):1042. doi: 10.1016/j.kint.2019.04.013. No abstract available.


An Evaluation of CD61 Immunohistochemistry in Identification of Vascular Invasion in Follicular Thyroid Neoplasms.

Cracolici V, Parilla M, Henriksen KJ, Cipriani NA.

Head Neck Pathol. 2019 Jun 19. doi: 10.1007/s12105-019-01048-8. [Epub ahead of print]


Renal Vasculitis and Pauci-immune Glomerulonephritis Associated With Immune Checkpoint Inhibitors.

Gallan AJ, Alexander E, Reid P, Kutuby F, Chang A, Henriksen KJ.

Am J Kidney Dis. 2019 Dec;74(6):853-856. doi: 10.1053/j.ajkd.2019.04.016. Epub 2019 Jun 14.


Hematopoietic Stem Cell-Targeted Neonatal Gene Therapy with a Clinically Applicable Lentiviral Vector Corrects Osteopetrosis in oc/oc Mice.

Löfvall H, Rothe M, Schambach A, Henriksen K, Richter J, Moscatelli I.

Hum Gene Ther. 2019 Nov;30(11):1395-1404. doi: 10.1089/hum.2019.047. Epub 2019 Jul 3.


A dual amylin and calcitonin receptor agonist inhibits pain behavior and reduces cartilage pathology in an osteoarthritis rat model.

Katri A, Dąbrowska A, Löfvall H, Karsdal MA, Andreassen KV, Thudium CS, Henriksen K.

Osteoarthritis Cartilage. 2019 Sep;27(9):1339-1346. doi: 10.1016/j.joca.2019.05.016. Epub 2019 Jun 5.


Circulating Biomarkers of Testosterone's Anabolic Effects on Fat-Free Mass.

Huang G, Rocha GV, Pencina KM, Cox K, Krishnan V, Henriksen K, Mitchell P, Sissons SE, Li Z, Nedergaard AF, Karsdal MA, Sun S, Storer TW, Basaria S, Bhasin S.

J Clin Endocrinol Metab. 2019 May 23. pii: jc.2019-00505. doi: 10.1210/jc.2019-00505. [Epub ahead of print]


The Dual Amylin and Calcitonin Receptor Agonist KBP-088 Induces Weight Loss and Improves Insulin Sensitivity Superior to Chronic Amylin Therapy.

Larsen AT, Sonne N, Andreassen KV, Gehring K, Karsdal MA, Henriksen K.

J Pharmacol Exp Ther. 2019 Jul;370(1):35-43. doi: 10.1124/jpet.119.257576. Epub 2019 Apr 26.


Serum tau fragments as predictors of death or poor neurological outcome after out-of-hospital cardiac arrest.

Grand J, Kjaergaard J, Nielsen N, Friberg H, Cronberg T, Bro-Jeppesen J, Karsdal MA, Nielsen HB, Frydland M, Henriksen K, Mattsson N, Zetterberg H, Hassager C.

Biomarkers. 2019 Sep;24(6):584-591. doi: 10.1080/1354750X.2019.1609580. Epub 2019 May 31.


Biochemical and histological characterisation of an experimental rodent model of non-alcoholic steatohepatitis - Effects of a peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist and a glucagon-like peptide-1 analogue.

Daniels SJ, Leeming DJ, Detlefsen S, Bruun MF, Hjuler ST, Henriksen K, Hein P, Karsdal MA, Brockbank S, Cruwys S.

Biomed Pharmacother. 2019 Mar;111:926-933. doi: 10.1016/j.biopha.2018.12.130. Epub 2019 Jan 7.


P. aeruginosa flow-cell biofilms are enhanced by repeated phage treatments but can be eradicated by phage-ciprofloxacin combination.

Henriksen K, Rørbo N, Rybtke ML, Martinet MG, Tolker-Nielsen T, Høiby N, Middelboe M, Ciofu O.

Pathog Dis. 2019 Mar 1;77(2). pii: ftz011. doi: 10.1093/femspd/ftz011.


GPDPLQ1237-A Type II Collagen Neo-Epitope Biomarker of Osteoclast- and Inflammation-Derived Cartilage Degradation in vitro.

Löfvall H, Katri A, Dąbrowska A, Karsdal MA, Luo Y, He Y, Manon-Jensen T, Dziegiel MH, Bay-Jensen AC, Thudium CS, Henriksen K.

Sci Rep. 2019 Feb 28;9(1):3050. doi: 10.1038/s41598-019-39803-0.


Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model.

Katri A, Dąbrowska A, Löfvall H, Ding M, Karsdal MA, Andreassen KV, Thudium CS, Henriksen K.

Arthritis Res Ther. 2019 Feb 22;21(1):68. doi: 10.1186/s13075-019-1819-9.


Pursuing Patient Safety at the Intersection of Design, Systems Engineering, and Health Care Delivery Research: An Ongoing Assessment.

Henriksen K, Rodrick D, Grace EN, Shofer M, Jeffrey Brady P.

J Patient Saf. 2019 Feb 9. doi: 10.1097/PTS.0000000000000577. [Epub ahead of print]


The LASSO Program in Oslo: Harm Reduction Using Buprenorphine-Naloxone (Suboxone®) in a Low Threshold Setting.

Henriksen K, Jacobsen JA, Henriksen EM, Gomes L, Waal H, Krajci P.

Eur Addict Res. 2018;24(6):286-292. doi: 10.1159/000495188. Epub 2018 Nov 22.


A Novel High Sensitivity Type II Collagen Blood-Based Biomarker, PRO-C2, for Assessment of Cartilage Formation.

Luo Y, He Y, Reker D, Gudmann NS, Henriksen K, Simonsen O, Ladel C, Michaelis M, Mobasheri A, Karsdal M, Bay-Jensen AC.

Int J Mol Sci. 2018 Nov 6;19(11). pii: E3485. doi: 10.3390/ijms19113485.


The Architecture Of Safety: An Emerging Priority For Improving Patient Safety.

Joseph A, Henriksen K, Malone E.

Health Aff (Millwood). 2018 Nov;37(11):1884-1891. doi: 10.1377/hlthaff.2018.0643. Review.


Alterations in non-type I collagen biomarkers in osteogenesis imperfecta.

Nicol L, Morar P, Wang Y, Henriksen K, Sun S, Karsdal M, Smith R, Nagamani SCS, Shapiro J, Lee B, Orwoll E.

Bone. 2019 Mar;120:70-74. doi: 10.1016/j.bone.2018.09.024. Epub 2018 Oct 2.


A 2018 Reference Guide to the Banff Classification of Renal Allograft Pathology.

Roufosse C, Simmonds N, Clahsen-van Groningen M, Haas M, Henriksen KJ, Horsfield C, Loupy A, Mengel M, Perkowska-Ptasińska A, Rabant M, Racusen LC, Solez K, Becker JU.

Transplantation. 2018 Nov;102(11):1795-1814. doi: 10.1097/TP.0000000000002366. Review. Erratum in: Transplantation. 2018 Dec;102(12):e497.


Kidney Transplant Outcomes in 2 Adults With Down Syndrome.

Henriksen KJ, Chang A, Bayliss GP.

Kidney Int Rep. 2018 Mar 2;3(4):979-984. doi: 10.1016/j.ekir.2018.02.006. eCollection 2018 Jul. No abstract available.


In Reply.

Henriksen K, Rodrick D, Grace EN, Brady PJ.

Acad Med. 2018 May;93(5):673. doi: 10.1097/ACM.0000000000002163. No abstract available.


Are Sporadic Eosinophilic Solid and Cystic Renal Cell Carcinomas Characterized by Somatic Tuberous Sclerosis Gene Mutations?

Parilla M, Kadri S, Patil SA, Ritterhouse L, Segal J, Henriksen KJ, Antic T.

Am J Surg Pathol. 2018 Jul;42(7):911-917. doi: 10.1097/PAS.0000000000001067.


Two novel blood-based biomarker candidates measuring degradation of tau are associated with dementia: A prospective study.

Neergaard JS, Dragsbæk K, Christiansen C, Karsdal MA, Brix S, Henriksen K.

PLoS One. 2018 Apr 11;13(4):e0194802. doi: 10.1371/journal.pone.0194802. eCollection 2018.


Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes.

Löfvall H, Newbould H, Karsdal MA, Dziegiel MH, Richter J, Henriksen K, Thudium CS.

Arthritis Res Ther. 2018 Apr 10;20(1):67. doi: 10.1186/s13075-018-1564-5.


Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix.

Kehlet SN, Willumsen N, Armbrecht G, Dietzel R, Brix S, Henriksen K, Karsdal MA.

PLoS One. 2018 Mar 29;13(3):e0194458. doi: 10.1371/journal.pone.0194458. eCollection 2018.


Autopsy kidneys: an overlooked resource.

Henriksen KJ.

Autops Case Rep. 2018 Mar 2;8(1):e2018013. doi: 10.4322/acr.2018.013. eCollection 2018 Jan-Mar. No abstract available.


Challenges and opportunities from the Agency for Healthcare Research and Quality (AHRQ) research summit on improving diagnosis: a proceedings review.

Henriksen K, Dymek C, Harrison MI, Brady PJ, Arnold SB.

Diagnosis (Berl). 2017 Jun 27;4(2):57-66. doi: 10.1515/dx-2017-0016. Review.


Bowman capsulitis predicts poor kidney allograft outcome in T cell-mediated rejection.

Gallan AJ, Chon WJ, Josephson MA, Cunningham PN, Henriksen KJ, Chang A.

Hum Pathol. 2018 Jun;76:47-51. doi: 10.1016/j.humpath.2018.02.016. Epub 2018 Mar 6.


Successful use of rituximab in glomerular basement membrane nephritis associated with HIV interstitial nephritis secondary to Castleman disease

Calabro N, Henriksen K, Lim SH, Kerns E.

Clin Nephrol. 2018 Jun;89(6):469-473. doi: 10.5414/CN109344.


Objective Cognitive Impairment and Progression to Dementia in Women: The Prospective Epidemiological Risk Factor Study.

Skov Neergaard J, Dragsbæk K, Christiansen C, Asser Karsdal M, Brix S, Henriksen K.

J Prev Alzheimers Dis. 2017;4(3):194-200. doi: 10.14283/jpad.2017.4.


FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.

Wang XX, Wang D, Luo Y, Myakala K, Dobrinskikh E, Rosenberg AZ, Levi J, Kopp JB, Field A, Hill A, Lucia S, Qiu L, Jiang T, Peng Y, Orlicky D, Garcia G, Herman-Edelstein M, D'Agati V, Henriksen K, Adorini L, Pruzanski M, Xie C, Krausz KW, Gonzalez FJ, Ranjit S, Dvornikov A, Gratton E, Levi M.

J Am Soc Nephrol. 2018 Jan;29(1):118-137. doi: 10.1681/ASN.2017020222. Epub 2017 Oct 31.


Medical renal diseases are frequent but often unrecognized in adult autopsies.

Perrone ME, Chang A, Henriksen KJ.

Mod Pathol. 2018 Feb;31(2):365-373. doi: 10.1038/modpathol.2017.122. Epub 2017 Oct 6.


Challenges in Health Care Simulation: Are We Learning Anything New?

Henriksen K, Rodrick D, Grace EN, Brady PJ.

Acad Med. 2018 May;93(5):705-708. doi: 10.1097/ACM.0000000000001891.


Targeting NSG Mice Engrafting Cells with a Clinically Applicable Lentiviral Vector Corrects Osteoclasts in Infantile Malignant Osteopetrosis.

Moscatelli I, Löfvall H, Schneider Thudium C, Rothe M, Montano C, Kertész Z, Sirin M, Schulz A, Schambach A, Henriksen K, Richter J.

Hum Gene Ther. 2018 Aug;29(8):938-949. doi: 10.1089/hum.2017.053. Epub 2017 Oct 3.


Proliferative glomerulonephritis with monoclonal IgG deposits in two kidney allografts successfully treated with rituximab.

Merhi B, Patel N, Bayliss G, Henriksen KJ, Gohh R.

Clin Kidney J. 2017 Jun;10(3):405-410. doi: 10.1093/ckj/sfx001. Epub 2017 Mar 22.


Simulation Research in Gastrointestinal and Urologic Care-Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases and National Institute of Biomedical Imaging and Bioengineering Workshop.

Aggarwal R, Brown KM, de Groen PC, Gallagher AG, Henriksen K, Kavoussi LR, Peng GCY, Ritter EM, Silverman E, Wang KK, Andersen DK.

J Clin Gastroenterol. 2017 May 30. doi: 10.1097/MCG.0000000000000862. [Epub ahead of print]


Simulation Research in Gastrointestinal and Urologic Care-Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases and National Institute of Biomedical Imaging and Bioengineering Workshop.

Aggarwal R, Brown KM, de Groen PC, Gallagher AG, Henriksen K, Kavoussi LR, Peng GCY, Ritter EM, Silverman E, Wang KK, Andersen DK.

Ann Surg. 2018 Jan;267(1):26-34. doi: 10.1097/SLA.0000000000002228. Review.


Modifiable risk factors promoting neurodegeneration is associated with two novel brain degradation markers measured in serum.

Neergaard JS, Dragsbæk K, Christiansen C, Nielsen HB, Workman CT, Brix S, Henriksen K, Karsdal MA.

Neurochem Int. 2017 Sep;108:303-308. doi: 10.1016/j.neuint.2017.05.002. Epub 2017 May 10.


The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes.

Hjuler ST, Gydesen S, Andreassen KV, Karsdal MA, Henriksen K.

J Pharmacol Exp Ther. 2017 Jul;362(1):24-30. doi: 10.1124/jpet.117.241281. Epub 2017 Apr 24.


Metabolic Syndrome, Insulin Resistance, and Cognitive Dysfunction: Does Your Metabolic Profile Affect Your Brain?

Neergaard JS, Dragsbæk K, Christiansen C, Nielsen HB, Brix S, Karsdal MA, Henriksen K.

Diabetes. 2017 Jul;66(7):1957-1963. doi: 10.2337/db16-1444. Epub 2017 Apr 7.


Biomarker of extracellular matrix remodelling C1M and proinflammatory cytokine interleukin 6 are related to synovitis and pain in end-stage knee osteoarthritis patients.

Radojčić MR, Thudium CS, Henriksen K, Tan K, Karlsten R, Dudley A, Chessell I, Karsdal MA, Bay-Jensen AC, Crema MD, Guermazi A.

Pain. 2017 Jul;158(7):1254-1263. doi: 10.1097/j.pain.0000000000000908.


Optimization of tolerability and efficacy of the novel dual amylin and calcitonin receptor agonist KBP-089 through dose escalation and combination with a GLP-1 analog.

Gydesen S, Andreassen KV, Hjuler ST, Hellgren LI, Karsdal MA, Henriksen K.

Am J Physiol Endocrinol Metab. 2017 Nov 1;313(5):E598-E607. doi: 10.1152/ajpendo.00419.2016. Epub 2017 Mar 14.


Weight change and risk of hyperglycaemia in elderly women.

Dragsbæk K, Neergaard JS, Christiansen C, Karsdal MA, Beck-Nielsen H, Brix S, Henriksen K.

Aging Clin Exp Res. 2017 Dec;29(6):1095-1104. doi: 10.1007/s40520-016-0696-1. Epub 2017 Mar 6.


Forced expression of human macrophage colony-stimulating factor in CD34+ cells promotes monocyte differentiation in vitro and in vivo but blunts osteoclastogenesis in vitro.

Montano Almendras CP, Thudium CS, Löfvall H, Moscatelli I, Schambach A, Henriksen K, Richter J.

Eur J Haematol. 2017 May;98(5):517-526. doi: 10.1111/ejh.12867. Epub 2017 Mar 6.


A novel dual amylin and calcitonin receptor agonist, KBP-089, induces weight loss through a reduction in fat, but not lean mass, while improving food preference.

Gydesen S, Hjuler ST, Freving Z, Andreassen KV, Sonne N, Hellgren LI, Karsdal MA, Henriksen K.

Br J Pharmacol. 2017 Apr;174(7):591-602. doi: 10.1111/bph.13723. Epub 2017 Feb 15.


High throughput, quantitative analysis of human osteoclast differentiation and activity.

Diepenhorst NA, Nowell CJ, Rueda P, Henriksen K, Pierce T, Cook AE, Pastoureau P, Sabatini M, Charman WN, Christopoulos A, Summers RJ, Sexton PM, Langmead CJ.

Anal Biochem. 2017 Feb 15;519:51-56. doi: 10.1016/j.ab.2016.12.010. Epub 2016 Dec 14.


Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic.

O'Bryant SE, Mielke MM, Rissman RA, Lista S, Vanderstichele H, Zetterberg H, Lewczuk P, Posner H, Hall J, Johnson L, Fong YL, Luthman J, Jeromin A, Batrla-Utermann R, Villarreal A, Britton G, Snyder PJ, Henriksen K, Grammas P, Gupta V, Martins R, Hampel H; Biofluid Based Biomarker Professional Interest Area.

Alzheimers Dement. 2017 Jan;13(1):45-58. doi: 10.1016/j.jalz.2016.09.014. Epub 2016 Nov 18.


Neo-epitope Peptides as Biomarkers of Disease Progression for Muscular Dystrophies and Other Myopathies.

Arvanitidis A, Henriksen K, Karsdal MA, Nedergaard A.

J Neuromuscul Dis. 2016 Aug 30;3(3):333-346. Review.

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