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Items: 1 to 50 of 205

1.

Renal temperature reduction progressively favors mitochondrial ROS production over respiration in hypothermic kidney preservation.

Hendriks KDW, Brüggenwirth IMA, Maassen H, Gerding A, Bakker B, Porte RJ, Henning RH, Leuvenink HGD.

J Transl Med. 2019 Aug 13;17(1):265. doi: 10.1186/s12967-019-2013-1.

2.

Gasotransmitters in health and disease: a mitochondria-centered view.

Hendriks KD, Maassen H, van Dijk PR, Henning RH, van Goor H, Hillebrands JL.

Curr Opin Pharmacol. 2019 Apr;45:87-93. doi: 10.1016/j.coph.2019.07.001. Epub 2019 Jul 17. Review.

3.

DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation.

Zhang D, Hu X, Li J, Liu J, Baks-Te Bulte L, Wiersma M, Malik NU, van Marion DMS, Tolouee M, Hoogstra-Berends F, Lanters EAH, van Roon AM, de Vries AAF, Pijnappels DA, de Groot NMS, Henning RH, Brundel BJJM.

Nat Commun. 2019 Mar 21;10(1):1307. doi: 10.1038/s41467-019-09014-2.

4.

Screening of novel HSP-inducing compounds to conserve cardiomyocyte function in experimental atrial fibrillation.

van Marion DM, Hu X, Zhang D, Hoogstra-Berends F, Seerden JG, Loen L, Heeres A, Steen H, Henning RH, Brundel BJ.

Drug Des Devel Ther. 2019 Jan 18;13:345-364. doi: 10.2147/DDDT.S176924. eCollection 2019.

5.

The (R)-enantiomer of the 6-chromanol derivate SUL-121 improves renal graft perfusion via antagonism of the α1-adrenoceptor.

Nakladal D, Buikema H, Romero AR, Lambooy SPH, Bouma J, Krenning G, Vogelaar P, van der Graaf AC, Groves MR, Kyselovic J, Henning RH, Deelman LE.

Sci Rep. 2019 Jan 9;9(1):13. doi: 10.1038/s41598-018-36788-0.

6.

Metabolic Resuscitation Strategies to Prevent Organ Dysfunction in Sepsis.

Reitsema VA, Star BS, de Jager VD, van Meurs M, Henning RH, Bouma HR.

Antioxid Redox Signal. 2019 Jul 10;31(2):134-152. doi: 10.1089/ars.2018.7537. Epub 2019 Jan 23.

PMID:
30403161
7.

Converse role of class I and class IIa HDACs in the progression of atrial fibrillation.

Zhang D, Hu X, Li J, Hoogstra-Berends F, Zhuang Q, Esteban MA, de Groot N, Henning RH, Brundel BJJM.

J Mol Cell Cardiol. 2018 Dec;125:39-49. doi: 10.1016/j.yjmcc.2018.09.010. Epub 2018 Oct 12.

8.

Reply.

Bouma HR, Mungroop HE, Henning RH, Epema AH.

Ann Thorac Surg. 2018 Dec;106(6):1891-1892. doi: 10.1016/j.athoracsur.2018.07.006. Epub 2018 Aug 11. No abstract available.

PMID:
30107141
9.

Application of kinomic array analysis to screen for altered kinases in atrial fibrillation remodeling.

Meijering RAM, Wiersma M, Zhang D, Lanters EAH, Hoogstra-Berends F, Scholma J, Diks S, Qi X, de Groot NMS, Nattel S, Henning RH, Brundel BJJM.

Heart Rhythm. 2018 Nov;15(11):1708-1716. doi: 10.1016/j.hrthm.2018.06.014. Epub 2018 Jun 11.

PMID:
29902583
10.

Torpor-arousal cycles in Syrian hamster heart are associated with transient activation of the protein quality control system.

Wiersma M, Beuren TMA, de Vrij EL, Reitsema VA, Bruintjes JJ, Bouma HR, Brundel BJJM, Henning RH.

Comp Biochem Physiol B Biochem Mol Biol. 2018 Sep;223:23-28. doi: 10.1016/j.cbpb.2018.06.001. Epub 2018 Jun 9.

PMID:
29894736
11.

The 6-hydroxychromanol derivative SUL-109 ameliorates renal injury after deep hypothermia and rewarming in rats.

Vogelaar PC, Roorda M, de Vrij EL, Houwertjes MC, Goris M, Bouma H, van der Graaf AC, Krenning G, Henning RH.

Nephrol Dial Transplant. 2018 Dec 1;33(12):2128-2138. doi: 10.1093/ndt/gfy080.

PMID:
29660027
12.

Acute Kidney Injury Classification Underestimates Long-Term Mortality After Cardiac Valve Operations.

Bouma HR, Mungroop HE, de Geus AF, Huisman DD, Nijsten MWN, Mariani MA, Scheeren TWL, Burgerhof JGM, Henning RH, Epema AH.

Ann Thorac Surg. 2018 Jul;106(1):92-98. doi: 10.1016/j.athoracsur.2018.01.066. Epub 2018 Mar 1.

PMID:
29501641
13.

Modulation of glutathione peroxidase activity by age-dependent carbonylation in glomeruli of diabetic mice.

Wiedenmann T, Dietrich N, Fleming T, Altamura S, Deelman LE, Henning RH, Muckenthaler MU, Nawroth PP, Hammes HP, Wagner AH, Hecker M.

J Diabetes Complications. 2018 Feb;32(2):130-138. doi: 10.1016/j.jdiacomp.2017.11.007. Epub 2017 Nov 22.

PMID:
29223856
14.

Gastrointestinal tuberculosis following renal transplantation accompanied with septic shock and acute respiratory distress syndrome: a survival case presentation.

Cikova A, Vavrincova-Yaghi D, Vavrinec P, Dobisova A, Gebhardtova A, Flassikova Z, Seelen MA, Henning RH, Yaghi A.

BMC Gastroenterol. 2017 Nov 28;17(1):131. doi: 10.1186/s12876-017-0695-5.

15.

Differences in mitochondrial function and morphology during cooling and rewarming between hibernator and non-hibernator derived kidney epithelial cells.

Hendriks KDW, Lupi E, Hardenberg MC, Hoogstra-Berends F, Deelman LE, Henning RH.

Sci Rep. 2017 Nov 14;7(1):15482. doi: 10.1038/s41598-017-15606-z.

16.

Endoplasmic Reticulum Stress Is Associated With Autophagy and Cardiomyocyte Remodeling in Experimental and Human Atrial Fibrillation.

Wiersma M, Meijering RAM, Qi XY, Zhang D, Liu T, Hoogstra-Berends F, Sibon OCM, Henning RH, Nattel S, Brundel BJJM.

J Am Heart Assoc. 2017 Oct 24;6(10). pii: e006458. doi: 10.1161/JAHA.117.006458.

17.

Brain inflammatory cytokines and microglia morphology changes throughout hibernation phases in Syrian hamster.

Cogut V, Bruintjes JJ, Eggen BJL, van der Zee EA, Henning RH.

Brain Behav Immun. 2018 Feb;68:17-22. doi: 10.1016/j.bbi.2017.10.009. Epub 2017 Oct 14.

PMID:
29038037
18.

The Novel Compound Sul-121 Preserves Endothelial Function and Inhibits Progression of Kidney Damage in Type 2 Diabetes Mellitus in Mice.

Lambooy SPH, Bidadkosh A, Nakladal D, van Buiten A, Girgis RAT, van der Graaf AC, Wiedenmann TJ, Koster RA, Vogelaar P, Buikema H, Henning RH, Deelman LE.

Sci Rep. 2017 Sep 11;7(1):11165. doi: 10.1038/s41598-017-11582-6.

19.

Metformin Improves Endothelial Function and Reduces Blood Pressure in Diabetic Spontaneously Hypertensive Rats Independent from Glycemia Control: Comparison to Vildagliptin.

Hamidi Shishavan M, Henning RH, van Buiten A, Goris M, Deelman LE, Buikema H.

Sci Rep. 2017 Sep 8;7(1):10975. doi: 10.1038/s41598-017-11430-7.

20.

A Hibernation-Like State for Transplantable Organs: Is Hydrogen Sulfide Therapy the Future of Organ Preservation?

Dugbartey GJ, Bouma HR, Saha MN, Lobb I, Henning RH, Sener A.

Antioxid Redox Signal. 2018 Jun 1;28(16):1503-1515. doi: 10.1089/ars.2017.7127. Epub 2017 Aug 29.

PMID:
28747071
21.

Proteostasis in cardiac health and disease.

Henning RH, Brundel BJJM.

Nat Rev Cardiol. 2017 Nov;14(11):637-653. doi: 10.1038/nrcardio.2017.89. Epub 2017 Jun 29. Review.

PMID:
28660894
22.

Predictive Properties of Biomarkers GDF-15, NTproBNP, and hs-TnT for Morbidity and Mortality in Patients With Type 2 Diabetes With Nephropathy.

Bidadkosh A, Lambooy SPH, Heerspink HJ, Pena MJ, Henning RH, Buikema H, Deelman LE.

Diabetes Care. 2017 Jun;40(6):784-792. doi: 10.2337/dc16-2175. Epub 2017 Mar 24.

PMID:
28341782
23.

The influence of sex and diet on the characteristics of hibernation in Syrian hamsters.

Trefna M, Goris M, Thissen CMC, Reitsema VA, Bruintjes JJ, de Vrij EL, Bouma HR, Boerema AS, Henning RH.

J Comp Physiol B. 2017 Jul;187(5-6):725-734. doi: 10.1007/s00360-017-1072-y. Epub 2017 Mar 21.

24.

Renal Mitochondrial Response to Low Temperature in Non-Hibernating and Hibernating Species.

Dugbartey GJ, Hardenberg MC, Kok WF, Boerema AS, Carey HV, Staples JF, Henning RH, Bouma HR.

Antioxid Redox Signal. 2017 Sep 20;27(9):599-617. doi: 10.1089/ars.2016.6705. Epub 2017 Apr 26. Review.

PMID:
28322600
25.

The 6-chromanol derivate SUL-109 enables prolonged hypothermic storage of adipose tissue-derived stem cells.

Hajmousa G, Vogelaar P, Brouwer LA, van der Graaf AC, Henning RH, Krenning G.

Biomaterials. 2017 Mar;119:43-52. doi: 10.1016/j.biomaterials.2016.12.008. Epub 2016 Dec 9.

PMID:
28006657
26.

Local gene therapy with indoleamine 2,3-dioxygenase protects against development of transplant vasculopathy in chronic kidney transplant dysfunction.

Vavrincova-Yaghi D, Deelman LE, van Goor H, Seelen MA, Vavrinec P, Kema IP, Gomolcak P, Benigni A, Henning RH, Sandovici M.

Gene Ther. 2016 Nov;23(11):820. doi: 10.1038/gt.2016.68. No abstract available.

PMID:
27808123
27.

Local gene therapy with indoleamine 2,3-dioxygenase protects against development of transplant vasculopathy in chronic kidney transplant dysfunction.

Vavrincova-Yaghi D, Deelman LE, van Goor H, Seelen MA, Vavrinec P, Kema IP, Gomolcak P, Benigni A, Henning RH, Sandovici M.

Gene Ther. 2016 Nov;23(11):797-806. doi: 10.1038/gt.2016.59. Epub 2016 Jul 25. Erratum in: Gene Ther. 2016 Nov;23 (11):820.

PMID:
27454318
28.

Differential Effects of Long Term FTY720 Treatment on Endothelial versus Smooth Muscle Cell Signaling to S1P in Rat Mesenteric Arteries.

Hamidi Shishavan M, Bidadkosh A, Yazdani S, Lambooy S, van den Born J, Buikema H, Henning RH, Deelman LE.

PLoS One. 2016 Sep 1;11(9):e0162029. doi: 10.1371/journal.pone.0162029. eCollection 2016.

29.

Neuroprotective hypothermia - Why keep your head cool during ischemia and reperfusion.

Talma N, Kok WF, de Veij Mestdagh CF, Shanbhag NC, Bouma HR, Henning RH.

Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2521-2528. doi: 10.1016/j.bbagen.2016.07.024. Epub 2016 Jul 28. Review.

PMID:
27475000
30.

Derailed Proteostasis as a Determinant of Cardiac Aging.

Wiersma M, Henning RH, Brundel BJ.

Can J Cardiol. 2016 Sep;32(9):1166.e11-20. doi: 10.1016/j.cjca.2016.03.005. Epub 2016 Mar 19. Review.

PMID:
27345610
31.

Long-term survival in permanent middle cerebral artery occlusion: a model of malignant stroke in rats.

Shanbhag NC, Henning RH, Schilling L.

Sci Rep. 2016 Jun 22;6:28401. doi: 10.1038/srep28401.

32.

The novel compound Sul-121 inhibits airway inflammation and hyperresponsiveness in experimental models of chronic obstructive pulmonary disease.

Han B, Poppinga WJ, Zuo H, Zuidhof AB, Bos IS, Smit M, Vogelaar P, Krenning G, Henning RH, Maarsingh H, Halayko AJ, van Vliet B, Stienstra S, Graaf AC, Meurs H, Schmidt M.

Sci Rep. 2016 May 27;6:26928. doi: 10.1038/srep26928.

33.

Renal endothelial function is associated with the anti-proteinuric effect of ACE inhibition in 5/6 nephrectomized rats.

Vettoretti S, Vavrinec P, Ochodnicky P, Deelman LE, De Zeeuw D, Henning RH, Buikema H.

Am J Physiol Renal Physiol. 2016 May 1;310(10):F1047-53. doi: 10.1152/ajprenal.00325.2015. Epub 2016 Feb 24.

34.

Keeping up the balance: role of HDACs in cardiac proteostasis and therapeutic implications for atrial fibrillation.

Zhang D, Hu X, Henning RH, Brundel BJ.

Cardiovasc Res. 2016 Apr 1;109(4):519-26. doi: 10.1093/cvr/cvv265. Epub 2015 Dec 8. Review.

PMID:
26645980
35.

Dopamine treatment attenuates acute kidney injury in a rat model of deep hypothermia and rewarming - The role of renal H2S-producing enzymes.

Dugbartey GJ, Talaei F, Houwertjes MC, Goris M, Epema AH, Bouma HR, Henning RH.

Eur J Pharmacol. 2015 Dec 15;769:225-33. doi: 10.1016/j.ejphar.2015.11.022. Epub 2015 Nov 21.

PMID:
26593431
36.

Induction of a Torpor-Like State by 5'-AMP Does Not Depend on H2S Production.

Dugbartey GJ, Bouma HR, Strijkstra AM, Boerema AS, Henning RH.

PLoS One. 2015 Aug 21;10(8):e0136113. doi: 10.1371/journal.pone.0136113. eCollection 2015.

37.

RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response.

Meijering RA, Wiersma M, van Marion DM, Zhang D, Hoogstra-Berends F, Dijkhuis AJ, Schmidt M, Wieland T, Kampinga HH, Henning RH, Brundel BJ.

PLoS One. 2015 Jul 20;10(7):e0133553. doi: 10.1371/journal.pone.0133553. eCollection 2015.

38.

Early Posttransplant Tryptophan Metabolism Predicts Long-term Outcome of Human Kidney Transplantation.

Vavrincova-Yaghi D, Seelen MA, Kema IP, Deelman LE, van der Heuvel MC, Breukelman H, Van den Eynde BJ, Henning RH, van Goor H, Sandovici M.

Transplantation. 2015 Aug;99(8):e97-104. doi: 10.1097/TP.0000000000000603.

PMID:
25651307
39.

How hibernation and hypothermia help to improve anticoagulant control.

de Vrij EL, Henning RH.

Temperature (Austin). 2014 Sep 25;2(1):44-6. doi: 10.4161/23328940.2014.967595. eCollection 2015 Jan-Mar.

40.

Reviving the protein quality control system: therapeutic target for cardiac disease in the elderly.

Meijering RA, Henning RH, Brundel BJ.

Trends Cardiovasc Med. 2015 Apr;25(3):243-7. doi: 10.1016/j.tcm.2014.10.013. Epub 2014 Oct 28. Review.

PMID:
25528995
41.

A case of severe chlorite poisoning successfully treated with early administration of methylene blue, renal replacement therapy, and red blood cell transfusion: case report.

Gebhardtova A, Vavrinec P, Vavrincova-Yaghi D, Seelen M, Dobisova A, Flassikova Z, Cikova A, Henning RH, Yaghi A.

Medicine (Baltimore). 2014 Aug;93(9):e60. doi: 10.1097/MD.0000000000000060.

42.

S1P1 receptor modulation preserves vascular function in mesenteric and coronary arteries after CPB in the rat independent of depletion of lymphocytes.

Samarska IV, Bouma HR, Buikema H, Mungroop HE, Houwertjes MC, Absalom AR, Epema AH, Henning RH.

PLoS One. 2014 May 12;9(5):e97196. doi: 10.1371/journal.pone.0097196. eCollection 2014.

43.

Platelet dynamics during natural and pharmacologically induced torpor and forced hypothermia.

de Vrij EL, Vogelaar PC, Goris M, Houwertjes MC, Herwig A, Dugbartey GJ, Boerema AS, Strijkstra AM, Bouma HR, Henning RH.

PLoS One. 2014 Apr 10;9(4):e93218. doi: 10.1371/journal.pone.0093218. eCollection 2014.

44.

Pioglitazone, a PPARγ agonist, provides comparable protection to angiotensin converting enzyme inhibitor ramipril against adriamycin nephropathy in rat.

Ochodnicky P, Mesarosova L, Cernecka H, Klimas J, Krenek P, Goris M, van Dokkum RP, Henning RH, Kyselovic J.

Eur J Pharmacol. 2014 May 5;730:51-60. doi: 10.1016/j.ejphar.2014.02.023. Epub 2014 Feb 28.

PMID:
24582928
45.

Hippocampal cystathionine beta synthase in young and aged mice.

Bruintjes JJ, Henning RH, Douwenga W, van der Zee EA.

Neurosci Lett. 2014 Mar 20;563:135-9. doi: 10.1016/j.neulet.2014.01.049. Epub 2014 Feb 1.

PMID:
24491430
46.

Increased protein aggregation in Zucker diabetic fatty rat brain: identification of key mechanistic targets and the therapeutic application of hydrogen sulfide.

Talaei F, Van Praag VM, Shishavan MH, Landheer SW, Buikema H, Henning RH.

BMC Cell Biol. 2014 Jan 6;15:1. doi: 10.1186/1471-2121-15-1.

47.

Ultrasound and microbubble-targeted delivery of small interfering RNA into primary endothelial cells is more effective than delivery of plasmid DNA.

Juffermans LJ, Meijering BD, Henning RH, Deelman LE.

Ultrasound Med Biol. 2014 Mar;40(3):532-40. doi: 10.1016/j.ultrasmedbio.2013.09.031. Epub 2013 Dec 19.

PMID:
24361223
48.

Endothelium-dependent relaxation and angiotensin II sensitivity in experimental preeclampsia.

van der Graaf AM, Wiegman MJ, Plösch T, Zeeman GG, van Buiten A, Henning RH, Buikema H, Faas MM.

PLoS One. 2013 Nov 6;8(11):e79884. doi: 10.1371/journal.pone.0079884. eCollection 2013.

49.

Activation of histone deacetylase-6 induces contractile dysfunction through derailment of α-tubulin proteostasis in experimental and human atrial fibrillation.

Zhang D, Wu CT, Qi X, Meijering RA, Hoogstra-Berends F, Tadevosyan A, Cubukcuoglu Deniz G, Durdu S, Akar AR, Sibon OC, Nattel S, Henning RH, Brundel BJ.

Circulation. 2014 Jan 21;129(3):346-58. doi: 10.1161/CIRCULATIONAHA.113.005300. Epub 2013 Oct 21.

PMID:
24146251
50.

Vildagliptin restores renal myogenic function and attenuates renal sclerosis independently of effects on blood glucose or proteinuria in zucker diabetic fatty rat.

Vavrinec P, Henning RH, Landheer SW, Wang Y, Deelman LE, Dokkum RP, Buikema H.

Curr Vasc Pharmacol. 2014;12(6):836-44.

PMID:
24066937

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