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Items: 32

1.

Subcellular Compartmentalization of Survivin is Associated with Biological Aggressiveness and Prognosis in Prostate Cancer.

Hennigs JK, Minner S, Tennstedt P, Löser R, Huland H, Klose H, Graefen M, Schlomm T, Sauter G, Bokemeyer C, Honecker F.

Sci Rep. 2020 Feb 24;10(1):3250. doi: 10.1038/s41598-020-60064-9.

2.

The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia.

Velthaus A, Cornils K, Hennigs JK, Grüb S, Stamm H, Wicklein D, Bokemeyer C, Heuser M, Windhorst S, Fiedler W, Wellbrock J.

Cancers (Basel). 2019 Oct 26;11(11). pii: E1663. doi: 10.3390/cancers11111663.

3.

The P2-receptor-mediated Ca2+ signalosome of the human pulmonary endothelium - implications for pulmonary arterial hypertension.

Hennigs JK, Lüneburg N, Stage A, Schmitz M, Körbelin J, Harbaum L, Matuszcak C, Mienert J, Bokemeyer C, Böger RH, Kiefmann R, Klose H.

Purinergic Signal. 2019 Sep;15(3):299-311. doi: 10.1007/s11302-019-09674-1. Epub 2019 Aug 8.

4.

PPARγ Interaction with UBR5/ATMIN Promotes DNA Repair to Maintain Endothelial Homeostasis.

Li CG, Mahon C, Sweeney NM, Verschueren E, Kantamani V, Li D, Hennigs JK, Marciano DP, Diebold I, Abu-Halawa O, Elliott M, Sa S, Guo F, Wang L, Cao A, Guignabert C, Sollier J, Nickel NP, Kaschwich M, Cimprich KA, Rabinovitch M.

Cell Rep. 2019 Jan 29;26(5):1333-1343.e7. doi: 10.1016/j.celrep.2019.01.013.

5.

Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1-Mediated Metabolic and Epigenetic Changes.

Miyagawa K, Shi M, Chen PI, Hennigs JK, Zhao Z, Wang M, Li CG, Saito T, Taylor S, Sa S, Cao A, Wang L, Snyder MP, Rabinovitch M.

Circ Res. 2019 Jan 18;124(2):211-224. doi: 10.1161/CIRCRESAHA.118.313374.

6.

Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018.

Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kuebler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT.

Int J Cardiol. 2018 Dec 1;272S:4-10. doi: 10.1016/j.ijcard.2018.09.070. Epub 2018 Sep 20. Review.

PMID:
30314839
7.

Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase.

Klinke A, Berghausen E, Friedrichs K, Molz S, Lau D, Remane L, Berlin M, Kaltwasser C, Adam M, Mehrkens D, Mollenhauer M, Manchanda K, Ravekes T, Heresi GA, Aytekin M, Dweik RA, Hennigs JK, Kubala L, Michaëlsson E, Rosenkranz S, Rudolph TK, Hazen SL, Klose H, Schermuly RT, Rudolph V, Baldus S.

JCI Insight. 2018 Jun 7;3(11). pii: 97530. doi: 10.1172/jci.insight.97530. eCollection 2018 Jun 7.

8.

Role of Toll-like receptors and interferon regulatory factors in different experimental heart failure models of diverse etiology: IRF7 as novel cardiovascular stress-inducible factor.

Becher PM, Hinrichs S, Fluschnik N, Hennigs JK, Klingel K, Blankenberg S, Westermann D, Lindner D.

PLoS One. 2018 Mar 14;13(3):e0193844. doi: 10.1371/journal.pone.0193844. eCollection 2018.

9.

Upregulation of Human Endogenous Retrovirus-K Is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension.

Saito T, Miyagawa K, Chen SY, Tamosiuniene R, Wang L, Sharpe O, Samayoa E, Harada D, Moonen JAJ, Cao A, Chen PI, Hennigs JK, Gu M, Li CG, Leib RD, Li D, Adams CM, Del Rosario PA, Bill M, Haddad F, Montoya JG, Robinson WH, Fantl WJ, Nolan GP, Zamanian RT, Nicolls MR, Chiu CY, Ariza ME, Rabinovitch M.

Circulation. 2017 Nov 14;136(20):1920-1935. doi: 10.1161/CIRCULATIONAHA.117.027589. Epub 2017 Sep 21.

10.

Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension.

Chen PI, Cao A, Miyagawa K, Tojais NF, Hennigs JK, Li CG, Sweeney NM, Inglis AS, Wang L, Li D, Ye M, Feldman BJ, Rabinovitch M.

JCI Insight. 2017 Jan 26;2(2):e90427. doi: 10.1172/jci.insight.90427.

11.

Acute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension.

Harbaum L, Renk E, Yousef S, Glatzel A, Lüneburg N, Hennigs JK, Oqueka T, Baumann HJ, Atanackovic D, Grünig E, Böger RH, Bokemeyer C, Klose H.

BMC Pulm Med. 2016 Nov 11;16(1):145.

12.

[Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016].

Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kübler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT.

Dtsch Med Wochenschr. 2016 Oct;141(S 01):S4-S9. Epub 2016 Oct 19. German.

PMID:
27760444
13.

Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial Hypertension.

Yuan K, Shao NY, Hennigs JK, Discipulo M, Orcholski ME, Shamskhou E, Richter A, Hu X, Wu JC, de Jesus Perez VA.

Am J Pathol. 2016 Sep;186(9):2500-14. doi: 10.1016/j.ajpath.2016.05.016. Epub 2016 Jul 25.

14.

In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug.

Hopper RK, Moonen JR, Diebold I, Cao A, Rhodes CJ, Tojais NF, Hennigs JK, Gu M, Wang L, Rabinovitch M.

Circulation. 2016 May 3;133(18):1783-94. doi: 10.1161/CIRCULATIONAHA.115.020617. Epub 2016 Apr 4.

15.

Does circulating IL-17 identify a subset of patients with idiopathic pulmonary arterial hypertension?

Harbaum L, Oqueka T, Glatzel A, Hennigs JK, Lüneburg N, Klose H.

Chest. 2015 Oct;148(4):e131-e132. doi: 10.1378/chest.15-0963. No abstract available.

PMID:
26437826
16.

Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus.

Raaz U, Schellinger IN, Chernogubova E, Warnecke C, Kayama Y, Penov K, Hennigs JK, Salomons F, Eken S, Emrich FC, Zheng WH, Adam M, Jagger A, Nakagami F, Toh R, Toyama K, Deng A, Buerke M, Maegdefessel L, Hasenfuß G, Spin JM, Tsao PS.

Circ Res. 2015 Aug 28;117(6):513-24. doi: 10.1161/CIRCRESAHA.115.306341. Epub 2015 Jul 24.

17.

RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension.

Rhodes CJ, Im H, Cao A, Hennigs JK, Wang L, Sa S, Chen PI, Nickel NP, Miyagawa K, Hopper RK, Tojais NF, Li CG, Gu M, Spiekerkoetter E, Xian Z, Chen R, Zhao M, Kaschwich M, Del Rosario PA, Bernstein D, Zamanian RT, Wu JC, Snyder MP, Rabinovitch M.

Am J Respir Crit Care Med. 2015 Aug 1;192(3):356-66. doi: 10.1164/rccm.201408-1528OC.

18.

Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension.

Wellbrock J, Harbaum L, Stamm H, Hennigs JK, Schulz B, Klose H, Bokemeyer C, Fiedler W, Lüneburg N.

Lung. 2015 Aug;193(4):567-70. doi: 10.1007/s00408-015-9735-5. Epub 2015 Apr 30.

PMID:
25926293
19.

BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension.

Diebold I, Hennigs JK, Miyagawa K, Li CG, Nickel NP, Kaschwich M, Cao A, Wang L, Reddy S, Chen PI, Nakahira K, Alcazar MA, Hopper RK, Ji L, Feldman BJ, Rabinovitch M.

Cell Metab. 2015 Apr 7;21(4):596-608. doi: 10.1016/j.cmet.2015.03.010.

20.

Elafin Reverses Pulmonary Hypertension via Caveolin-1-Dependent Bone Morphogenetic Protein Signaling.

Nickel NP, Spiekerkoetter E, Gu M, Li CG, Li H, Kaschwich M, Diebold I, Hennigs JK, Kim KY, Miyagawa K, Wang L, Cao A, Sa S, Jiang X, Stockstill RW, Nicolls MR, Zamanian RT, Bland RD, Rabinovitch M.

Am J Respir Crit Care Med. 2015 Jun 1;191(11):1273-86. doi: 10.1164/rccm.201412-2291OC.

21.

Enhanced caspase activity contributes to aortic wall remodeling and early aneurysm development in a murine model of Marfan syndrome.

Emrich FC, Okamura H, Dalal AR, Penov K, Merk DR, Raaz U, Hennigs JK, Chin JT, Miller MO, Pedroza AJ, Craig JK, Koyano TK, Blankenberg FG, Connolly AJ, Mohr FW, Alvira CM, Rabinovitch M, Fischbein MP.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):146-54. doi: 10.1161/ATVBAHA.114.304364. Epub 2014 Oct 30.

PMID:
25359856
22.

Loss of somatostatin receptor subtype 2 in prostate cancer is linked to an aggressive cancer phenotype, high tumor cell proliferation and predicts early metastatic and biochemical relapse.

Hennigs JK, Müller J, Adam M, Spin JM, Riedel E, Graefen M, Bokemeyer C, Sauter G, Huland H, Schlomm T, Minner S.

PLoS One. 2014 Jul 10;9(7):e100469. doi: 10.1371/journal.pone.0100469. eCollection 2014.

23.

Complete resolution of idiopathic pulmonary arterial hypertension following chemotherapy.

Harbaum L, Hennigs JK, Baumann HJ, Bokemeyer C, Olschewski H, Klose H.

Eur Respir J. 2014 May;43(5):1513-5. doi: 10.1183/09031936.00185713. No abstract available.

24.

Fibrinogen plasma concentration is an independent marker of haemodynamic impairment in chronic thromboembolic pulmonary hypertension.

Hennigs JK, Baumann HJ, Lüneburg N, Quast G, Harbaum L, Heyckendorf J, Sydow K, Schulte-Hubbert B, Halank M, Klose H.

Sci Rep. 2014 Apr 28;4:4808. doi: 10.1038/srep04808.

25.

N-terminal pro-brain natriuretic peptide is a useful prognostic marker in patients with pre-capillary pulmonary hypertension and renal insufficiency.

Harbaum L, Hennigs JK, Baumann HJ, Lüneburg N, Griesch E, Bokemeyer C, Grünig E, Klose H.

PLoS One. 2014 Apr 21;9(4):e94263. doi: 10.1371/journal.pone.0094263. eCollection 2014.

26.

The endothelial ADMA/NO pathway in hypoxia-related chronic respiratory diseases.

Lüneburg N, Harbaum L, Hennigs JK.

Biomed Res Int. 2014;2014:501612. doi: 10.1155/2014/501612. Epub 2014 Feb 25. Review.

27.

Low intensity, long-term outpatient rehabilitation in COPD: a randomised controlled trial.

Baumann HJ, Kluge S, Rummel K, Klose H, Hennigs JK, Schmoller T, Meyer A.

Respir Res. 2012 Sep 27;13:86. doi: 10.1186/1465-9921-13-86.

28.

Characterization of Enterobacter cloacae pneumonia: a single-center retrospective analysis.

Hennigs JK, Baumann HJ, Schmiedel S, Tennstedt P, Sobottka I, Bokemeyer C, Kluge S, Klose H.

Lung. 2011 Dec;189(6):475-83. doi: 10.1007/s00408-011-9323-2. Epub 2011 Oct 19.

PMID:
22009561
29.

Fiber optic bronchoscopy in patients with acute hypoxemic respiratory failure requiring noninvasive ventilation--a feasibility study.

Baumann HJ, Klose H, Simon M, Ghadban T, Braune SA, Hennigs JK, Kluge S.

Crit Care. 2011 Jul 27;15(4):R179. doi: 10.1186/cc10328.

30.

Molecular basis of P2-receptor-mediated calcium signaling in activated pancreatic stellate cells.

Hennigs JK, Seiz O, Spiro J, Berna MJ, Baumann HJ, Klose H, Pace A.

Pancreas. 2011 Jul;40(5):740-6. doi: 10.1097/MPA.0b013e31821b5b68.

PMID:
21654543
31.

Multi tyrosine kinase inhibitor dasatinib as novel cause of severe pre-capillary pulmonary hypertension?

Hennigs JK, Keller G, Baumann HJ, Honecker F, Kluge S, Bokemeyer C, Brümmendorf TH, Klose H.

BMC Pulm Med. 2011 May 23;11:30. doi: 10.1186/1471-2466-11-30.

32.

Sweet taste receptor interacting protein CIB1 is a general inhibitor of InsP3-dependent Ca2+ release in vivo.

Hennigs JK, Burhenne N, Stähler F, Winnig M, Walter B, Meyerhof W, Schmale H.

J Neurochem. 2008 Sep;106(5):2249-62. doi: 10.1111/j.1471-4159.2008.05563.x.

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