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Items: 1 to 50 of 144

1.

Monitoring of Tobramycin Exposure: What is the Best Estimation Method and Sampling Time for Clinical Practice?

Gao Y, Hennig S, Barras M.

Clin Pharmacokinet. 2018 Aug 24. doi: 10.1007/s40262-018-0707-9. [Epub ahead of print]

PMID:
30140975
2.

DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome.

Juratli TA, McCabe D, Nayyar N, Williams EA, Silverman IM, Tummala SS, Fink AL, Baig A, Martinez-Lage M, Selig MK, Bihun IV, Shankar GM, Penson T, Lastrapes M, Daubner D, Meinhardt M, Hennig S, Kaplan AB, Fujio S, Kuter BM, Bertalan MS, Miller JJ, Batten JM, Ely HA, Christiansen J, Baretton GB, Stemmer-Rachamimov AO, Santagata S, Rivera MN, Barker FG 2nd, Schackert G, Wakimoto H, Iafrate AJ, Carter SL, Cahill DP, Brastianos PK.

Acta Neuropathol. 2018 Aug 19. doi: 10.1007/s00401-018-1899-7. [Epub ahead of print]

PMID:
30123936
3.

RNA Structure and Cellular Applications of Fluorogenic Light-Up Aptamers.

Hennig S, Neubacher S.

Angew Chem Int Ed Engl. 2018 Aug 13. doi: 10.1002/anie.201806482. [Epub ahead of print]

PMID:
30102012
4.

Comment on "Effect of Age-Related Factors on the Pharmacokinetics of Lamotrigine and Potential Implications for Maintenance Dose Optimisation in Future Clinical Trials".

Standing JF, Anderson BJ, Hennig S, Holford NH, Johnston TN, Knibbe CAJ, Lonsdale DO, Rostami-Hodjegan A.

Clin Pharmacokinet. 2018 Jul 20. doi: 10.1007/s40262-018-0697-7. [Epub ahead of print] No abstract available.

PMID:
30027513
5.

TERT Promoter Mutation Detection in Cell-Free Tumor-Derived DNA in Patients with IDH Wild-Type Glioblastomas: A Pilot Prospective Study.

Juratli TA, Stasik S, Zolal A, Schuster C, Richter S, Daubner D, Juratli MA, Thowe R, Hennig S, Makina M, Meinhardt M, Lautenschlaeger T, Schackert G, Krex D, Thiede C.

Clin Cancer Res. 2018 Jun 25. doi: 10.1158/1078-0432.CCR-17-3717. [Epub ahead of print]

PMID:
29941484
6.

In Situ Cyclization of Native Proteins: Structure-Based Design of a Bicyclic Enzyme.

Pelay-Gimeno M, Bange T, Hennig S, Grossmann TN.

Angew Chem Int Ed Engl. 2018 Aug 27;57(35):11164-11170. doi: 10.1002/anie.201804506. Epub 2018 Jun 21.

7.

Identification of novel PANDAR protein interaction partners involved in splicing regulation.

Pospiech N, Cibis H, Dietrich L, Müller F, Bange T, Hennig S.

Sci Rep. 2018 Feb 12;8(1):2798. doi: 10.1038/s41598-018-21105-6.

8.

Bayesian Estimation of Tobramycin Exposure in Patients with Cystic Fibrosis: an Update.

Gao Y, Barras M, Hennig S.

Antimicrob Agents Chemother. 2018 Feb 23;62(3). pii: e01972-17. doi: 10.1128/AAC.01972-17. Print 2018 Mar. No abstract available.

9.

Population Pharmacokinetics of Lopinavir in Severely Malnourished HIV-infected Children and the Effect on Treatment Outcomes.

Archary M, Mcllleron H, Bobat R, Russa P, Sibaya T, Wiesner L, Hennig S.

Pediatr Infect Dis J. 2018 Apr;37(4):349-355. doi: 10.1097/INF.0000000000001867.

PMID:
29227461
10.

Balancing Antibacterial Efficacy and Reduction in Renal Function to Optimise Initial Gentamicin Dosing in Paediatric Oncology Patients.

Llanos-Paez CC, Staatz C, Hennig S.

AAPS J. 2017 Dec 4;20(1):14. doi: 10.1208/s12248-017-0173-6.

PMID:
29204823
11.

Pheromone-inducible expression vectors for fission yeast Schizosaccharomyces pombe.

Hennig S, Hornauer N, Rödel G, Ostermann K.

Plasmid. 2018 Jan;95:1-6. doi: 10.1016/j.plasmid.2017.11.002. Epub 2017 Nov 26.

PMID:
29183750
12.

Evaluation of Tobramycin Exposure Predictions in Three Bayesian Forecasting Programmes Compared with Current Clinical Practice in Children and Adults with Cystic Fibrosis.

Burgard M, Sandaradura I, van Hal SJ, Stacey S, Hennig S.

Clin Pharmacokinet. 2018 Aug;57(8):1017-1027. doi: 10.1007/s40262-017-0610-9.

PMID:
29134570
13.

Comparison of methods to estimate glomerular filtration rate in paediatric oncology patients.

Llanos-Paez CC, Staatz C, Lawson R, Hennig S.

J Paediatr Child Health. 2018 Feb;54(2):141-147. doi: 10.1111/jpc.13752. Epub 2017 Oct 30.

PMID:
29083076
14.

Using a Specific RNA-Protein Interaction To Quench the Fluorescent RNA Spinach.

Roszyk L, Kollenda S, Hennig S.

ACS Chem Biol. 2017 Dec 15;12(12):2958-2964. doi: 10.1021/acschembio.7b00332. Epub 2017 Nov 8.

PMID:
29058870
15.

Structure-Based Design of Non-natural Macrocyclic Peptides That Inhibit Protein-Protein Interactions.

Krüger DM, Glas A, Bier D, Pospiech N, Wallraven K, Dietrich L, Ottmann C, Koch O, Hennig S, Grossmann TN.

J Med Chem. 2017 Nov 9;60(21):8982-8988. doi: 10.1021/acs.jmedchem.7b01221. Epub 2017 Oct 27.

16.

Protein Dynamics in the Reductive Activation of a B12-Containing Enzyme.

Goetzl S, Teutloff C, Werther T, Hennig SE, Jeoung JH, Bittl R, Dobbek H.

Biochemistry. 2017 Oct 17;56(41):5496-5502. doi: 10.1021/acs.biochem.7b00477. Epub 2017 Oct 9.

PMID:
28949132
17.

Antimicrobial stewardship in paediatric oncology: Impact on optimising gentamicin use in febrile neutropenia.

Hennig S, Staatz CE, Natanek D, Bialkowski S, Consuelo Llanos Paez C, Lawson R, Clark J.

Pediatr Blood Cancer. 2018 Feb;65(2). doi: 10.1002/pbc.26810. Epub 2017 Sep 13.

PMID:
28901726
18.

Can Saliva and Plasma Methadone Concentrations Be Used for Enantioselective Pharmacokinetic and Pharmacodynamic Studies in Patients With Advanced Cancer?

George R, Haywood A, Good P, Hennig S, Khan S, Norris R, Hardy J.

Clin Ther. 2017 Sep;39(9):1840-1848. doi: 10.1016/j.clinthera.2017.07.044. Epub 2017 Aug 18.

PMID:
28827023
19.

Prediction of glycaemic control in young children and adolescents with type 1 diabetes mellitus using mixed-effects logistic regression modelling.

van Esdonk MJ, Tai B, Cotterill A, Charles B, Hennig S.

PLoS One. 2017 Aug 2;12(8):e0182181. doi: 10.1371/journal.pone.0182181. eCollection 2017.

20.

Erratum to: Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?

Kunarajah K, Hennig S, Norris RLG, Lobb M, Charles BG, Pinkerton R, Moore AS.

Cancer Chemother Pharmacol. 2017 Jul;80(1):27-28. doi: 10.1007/s00280-017-3338-1. No abstract available.

PMID:
28597037
21.

A Population Pharmacokinetic Model of Gentamicin in Pediatric Oncology Patients To Facilitate Personalized Dosing.

Llanos-Paez CC, Staatz CE, Lawson R, Hennig S.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00205-17. doi: 10.1128/AAC.00205-17. Print 2017 Aug.

22.

Population pharmacokinetic modelling of doxorubicin and doxorubicinol in children with cancer: is there a relationship with cardiac troponin profiles?

Kunarajah K, Hennig S, Norris RLG, Lobb M, Charles BG, Pinkerton R, Moore AS.

Cancer Chemother Pharmacol. 2017 Jul;80(1):15-25. doi: 10.1007/s00280-017-3309-6. Epub 2017 Apr 25. Erratum in: Cancer Chemother Pharmacol. 2017 Jul;80(1):27-28.

PMID:
28444427
23.

T-cell repertoires in refractory coeliac disease.

Ritter J, Zimmermann K, Jöhrens K, Mende S, Seegebarth A, Siegmund B, Hennig S, Todorova K, Rosenwald A, Daum S, Hummel M, Schumann M.

Gut. 2018 Apr;67(4):644-653. doi: 10.1136/gutjnl-2016-311816. Epub 2017 Feb 10.

24.

Survival rate of eukaryotic cells following electrophoretic nanoinjection.

Simonis M, Hübner W, Wilking A, Huser T, Hennig S.

Sci Rep. 2017 Jan 25;7:41277. doi: 10.1038/srep41277.

25.

Population pharmacokinetic modelling, Monte Carlo simulation and semi-mechanistic pharmacodynamic modelling as tools to personalize gentamicin therapy.

Llanos-Paez CC, Hennig S, Staatz CE.

J Antimicrob Chemother. 2017 Mar 1;72(3):639-667. doi: 10.1093/jac/dkw461. Review.

PMID:
28062683
26.

Gentamicin Pharmacokinetics and Monitoring in Pediatric Patients with Febrile Neutropenia.

Bialkowski S, Staatz CE, Clark J, Lawson R, Hennig S.

Ther Drug Monit. 2016 Dec;38(6):693-698.

PMID:
27851686
27.

Gentamicin Pharmacokinetics and Monitoring in Pediatric Febrile Neutropenic Patients.

Bialkowski S, Staatz CE, Clark J, Lawson R, Hennig S.

Ther Drug Monit. 2016 Sep 16. [Epub ahead of print]

PMID:
27661401
28.

Bayesian Estimation of Tobramycin Exposure in Patients with Cystic Fibrosis.

Barras MA, Serisier D, Hennig S, Jess K, Norris RL.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6698-6702. doi: 10.1128/AAC.01131-16. Print 2016 Nov.

29.

Axial Ligation and Redox Changes at the Cobalt Ion in Cobalamin Bound to Corrinoid Iron-Sulfur Protein (CoFeSP) or in Solution Characterized by XAS and DFT.

Schrapers P, Mebs S, Goetzl S, Hennig SE, Dau H, Dobbek H, Haumann M.

PLoS One. 2016 Jul 6;11(7):e0158681. doi: 10.1371/journal.pone.0158681. eCollection 2016.

30.

A systematic review of studies examining the rate of lung function decline in patients with cystic fibrosis.

Harun SN, Wainwright C, Klein K, Hennig S.

Paediatr Respir Rev. 2016 Sep;20:55-66. doi: 10.1016/j.prrv.2016.03.002. Epub 2016 Mar 14. Review.

PMID:
27259460
31.

Hydrophobin-Based Surface Engineering for Sensitive and Robust Quantification of Yeast Pheromones.

Hennig S, Rödel G, Ostermann K.

Sensors (Basel). 2016 Apr 27;16(5). pii: E602. doi: 10.3390/s16050602.

32.

11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

Fechner U, de Graaf C, Torda AE, Güssregen S, Evers A, Matter H, Hessler G, Richmond NJ, Schmidtke P, Segler MHS, Waller MP, Pleik S, Shea JE, Levine Z, Mullen R, van den Broek K, Epple M, Kuhn H, Truszkowski A, Zielesny A, Fraaije JH, Gracia RS, Kast SM, Bulusu KC, Bender A, Yosipof A, Nahum O, Senderowitz H, Krotzky T, Schulz R, Wolber G, Bietz S, Rarey M, Zimmermann MO, Lange A, Ruff M, Heidrich J, Onlia I, Exner TE, Boeckler FM, Bermudez M, Firaha DS, Hollóczki O, Kirchner B, Tautermann CS, Volkamer A, Eid S, Turk S, Rippmann F, Fulle S, Saleh N, Saladino G, Gervasio FL, Haensele E, Banting L, Whitley DC, Oliveira Santos JS, Bureau R, Clark T, Sandmann A, Lanig H, Kibies P, Heil J, Hoffgaard F, Frach R, Engel J, Smith S, Basu D, Rauh D, Kohlbacher O, Boeckler FM, Essex JW, Bodnarchuk MS, Ross GA, Finkelmann AR, Göller AH, Schneider G, Husch T, Schütter C, Balducci A, Korth M, Ntie-Kang F, Günther S, Sippl W, Mbaze LM, Ntie-Kang F, Simoben CV, Lifongo LL, Ntie-Kang F, Judson P, Barilla J, Lokajíček MV, Pisaková H, Simr P, Kireeva N, Petrov A, Ostroumov D, Solovev VP, Pervov VS, Friedrich NO, Sommer K, Rarey M, Kirchmair J, Proschak E, Weber J, Moser D, Kalinowski L, Achenbach J, Mackey M, Cheeseright T, Renner G, Renner G, Schmidt TC, Schram J, Egelkraut-Holtus M, van Oeyen A, Kalliokoski T, Fourches D, Ibezim A, Mbah CJ, Adikwu UM, Nwodo NJ, Steudle A, Masek BB, Nagy S, Baker D, Soltanshahi F, Dorfman R, Dubrucq K, Patel H, Koch O, Mrugalla F, Kast SM, Ain QU, Fuchs JE, Owen RM, Omoto K, Torella R, Pryde DC, Glen R, Bender A, Hošek P, Spiwok V, Mervin LH, Barrett I, Firth M, Murray DC, McWilliams L, Cao Q, Engkvist O, Warszycki D, Śmieja M, Bojarski AJ, Aniceto N, Freitas A, Ghafourian T, Herrmann G, Eigner-Pitto V, Naß A, Kurczab R, Bojarski AJ, Lange A, Günther MB, Hennig S, Büttner FM, Schall C, Sievers-Engler A, Ansideri F, Koch P, Stehle T, Laufer S, Böckler FM, Zdrazil B, Montanari F, Ecker GF, Grebner C, Hogner A, Ulander J, Edman K, Guallar V, Tyrchan C, Ulander J, Tyrchan C, Klute W, Bergström F, Kramer C, Nguyen QD, Frach R, Kibies P, Strohfeldt S, Böttcher S, Pongratz T, Horinek D, Kast SM, Rupp B, Al-Yamori R, Lisurek M, Kühne R, Furtado F, van den Broek K, Wessjohann L, Mathea M, Baumann K, Mohamad-Zobir SZ, Fu X, Fan TP, Bender A, Kuhn MA, Sotriffer CA, Zoufir A, Li X, Mervin L, Berg E, Polokoff M, Ihlenfeldt WD, Ihlenfeldt WD, Pretzel J, Alhalabi Z, Fraczkiewicz R, Waldman M, Clark RD, Shaikh N, Garg P, Kos A, Himmler HJ, Sandmann A, Jardin C, Sticht H, Steinbrecher TB, Dahlgren M, Cappel D, Lin T, Wang L, Krilov G, Abel R, Friesner R, Sherman W, Pöhner IA, Panecka J, Wade RC, Bietz S, Schomburg KT, Hilbig M, Rarey M, Jäger C, Wieczorek V, Westerhoff LM, Borbulevych OY, Demuth HU, Buchholz M, Schmidt D, Rickmeyer T, Krotzky T, Kolb P, Mittal S, Sánchez-García E, Nogueira MS, Oliveira TB, da Costa FB, Schmidt TJ.

J Cheminform. 2016 Apr 26;8(Suppl 1):18. doi: 10.1186/s13321-016-0119-5. No abstract available.

33.

A Bayesian Modelling Approach with Balancing Informative Prior for Analysing Imbalanced Data.

Klein K, Hennig S, Paul SK.

PLoS One. 2016 Apr 12;11(4):e0152700. doi: 10.1371/journal.pone.0152700. eCollection 2016.

34.

Assessing Predictive Performance of Published Population Pharmacokinetic Models of Intravenous Tobramycin in Pediatric Patients.

Bloomfield C, Staatz CE, Unwin S, Hennig S.

Antimicrob Agents Chemother. 2016 May 23;60(6):3407-14. doi: 10.1128/AAC.02654-15. Print 2016 Jun.

35.

Open-source image reconstruction of super-resolution structured illumination microscopy data in ImageJ.

Müller M, Mönkemöller V, Hennig S, Hübner W, Huser T.

Nat Commun. 2016 Mar 21;7:10980. doi: 10.1038/ncomms10980.

36.

Population pharmacokinetic drug-drug interaction pooled analysis of existing data for rifabutin and HIV PIs.

Hennig S, Svensson EM, Niebecker R, Fourie PB, Weiner MH, Bonora S, Peloquin CA, Gallicano K, Flexner C, Pym A, Vis P, Olliaro PL, McIlleron H, Karlsson MO.

J Antimicrob Chemother. 2016 May;71(5):1330-40. doi: 10.1093/jac/dkv470. Epub 2016 Jan 31.

37.

Structure of an Actinobacterial-Type [NiFe]-Hydrogenase Reveals Insight into O2-Tolerant H2 Oxidation.

Schäfer C, Bommer M, Hennig SE, Jeoung JH, Dobbek H, Lenz O.

Structure. 2016 Feb 2;24(2):285-92. doi: 10.1016/j.str.2015.11.010. Epub 2015 Dec 31.

38.

Quantitative determination of the enantiomers of methadone in human plasma and saliva by chiral column chromatography coupled with mass spectrometric detection.

George R, Lobb M, Haywood A, Khan S, Hardy J, Good P, Hennig S, Norris R.

Talanta. 2016;149:142-148. doi: 10.1016/j.talanta.2015.11.044. Epub 2015 Nov 19.

PMID:
26717824
39.

Targeting the Gatekeeper MET146 of C-Jun N-Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond.

Lange A, Günther M, Büttner FM, Zimmermann MO, Heidrich J, Hennig S, Zahn S, Schall C, Sievers-Engler A, Ansideri F, Koch P, Laemmerhofer M, Stehle T, Laufer SA, Boeckler FM.

J Am Chem Soc. 2015 Nov 25;137(46):14640-52. doi: 10.1021/jacs.5b07090. Epub 2015 Nov 12.

PMID:
26505827
40.

Effect of SLCO1B1 Polymorphisms on Rifabutin Pharmacokinetics in African HIV-Infected Patients with Tuberculosis.

Hennig S, Naiker S, Reddy T, Egan D, Kellerman T, Wiesner L, Owen A, McIlleron H, Pym A.

Antimicrob Agents Chemother. 2015 Oct 19;60(1):617-20. doi: 10.1128/AAC.01195-15. Print 2016 Jan.

41.

Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes.

Lee CU, Hahne G, Hanske J, Bange T, Bier D, Rademacher C, Hennig S, Grossmann TN.

Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13796-800. doi: 10.1002/anie.201506338. Epub 2015 Sep 29.

42.

Exposure to Fentanyl After Transdermal Patch Administration for Cancer Pain Management.

Bista SR, Haywood A, Hardy J, Norris R, Hennig S.

J Clin Pharmacol. 2016 Jun;56(6):705-13. doi: 10.1002/jcph.641. Epub 2015 Dec 31.

PMID:
26381285
43.

A systematic review of treatment outcomes with weight-based dosing of chemotherapy in obese adult patients with acute leukemia or lymphoma.

Mapp S, Sandhu G, Carrington C, Hennig S.

Leuk Lymphoma. 2016;57(4):981-4. doi: 10.3109/10428194.2015.1087520. Epub 2015 Oct 12. Review. No abstract available.

PMID:
26325127
44.

Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles.

Hennig S, Kong G, Mannen T, Sadowska A, Kobelke S, Blythe A, Knott GJ, Iyer KS, Ho D, Newcombe EA, Hosoki K, Goshima N, Kawaguchi T, Hatters D, Trinkle-Mulcahy L, Hirose T, Bond CS, Fox AH.

J Cell Biol. 2015 Aug 17;210(4):529-39. doi: 10.1083/jcb.201504117.

45.

Artificial cell-cell communication as an emerging tool in synthetic biology applications.

Hennig S, Rödel G, Ostermann K.

J Biol Eng. 2015 Aug 12;9:13. doi: 10.1186/s13036-015-0011-2. eCollection 2015.

46.

Tacrolimus pharmacokinetics after kidney transplantation--Influence of changes in haematocrit and steroid dose.

Staatz CE, Størset E, Bergmann TK, Hennig S, Holford N.

Br J Clin Pharmacol. 2015 Dec;80(6):1475-6. doi: 10.1111/bcp.12729. Epub 2015 Sep 15. No abstract available.

47.

Molecular Mechanisms by Which a Fucus vesiculosus Extract Mediates Cell Cycle Inhibition and Cell Death in Pancreatic Cancer Cells.

Geisen U, Zenthoefer M, Peipp M, Kerber J, Plenge J, Managò A, Fuhrmann M, Geyer R, Hennig S, Adam D, Piker L, Rimbach G, Kalthoff H.

Mar Drugs. 2015 Jul 20;13(7):4470-91. doi: 10.3390/md13074470.

48.

Quantitative Super-Resolution Microscopy of Nanopipette-Deposited Fluorescent Patterns.

Hennig S, van de Linde S, Bergmann S, Huser T, Sauer M.

ACS Nano. 2015 Aug 25;9(8):8122-30. doi: 10.1021/acsnano.5b02220. Epub 2015 Jul 21.

PMID:
26173009
49.

A new method to prevent carry-over contaminations in two-step PCR NGS library preparations.

Seitz V, Schaper S, Dröge A, Lenze D, Hummel M, Hennig S.

Nucleic Acids Res. 2015 Nov 16;43(20):e135. doi: 10.1093/nar/gkv694. Epub 2015 Jul 7.

50.

17 Ways to Say Yes: Toward Nuanced Tone of Voice in AAC and Speech Technology.

Pullin G, Hennig S.

Augment Altern Commun. 2015 Jun;31(2):170-80. doi: 10.3109/07434618.2015.1037930. Epub 2015 May 12.

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