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Items: 48

1.

Genetic analyses of diverse populations improves discovery for complex traits.

Wojcik GL, Graff M, Nishimura KK, Tao R, Haessler J, Gignoux CR, Highland HM, Patel YM, Sorokin EP, Avery CL, Belbin GM, Bien SA, Cheng I, Cullina S, Hodonsky CJ, Hu Y, Huckins LM, Jeff J, Justice AE, Kocarnik JM, Lim U, Lin BM, Lu Y, Nelson SC, Park SL, Poisner H, Preuss MH, Richard MA, Schurmann C, Setiawan VW, Sockell A, Vahi K, Verbanck M, Vishnu A, Walker RW, Young KL, Zubair N, Acuña-Alonso V, Ambite JL, Barnes KC, Boerwinkle E, Bottinger EP, Bustamante CD, Caberto C, Canizales-Quinteros S, Conomos MP, Deelman E, Do R, Doheny K, Fernández-Rhodes L, Fornage M, Hailu B, Heiss G, Henn BM, Hindorff LA, Jackson RD, Laurie CA, Laurie CC, Li Y, Lin DY, Moreno-Estrada A, Nadkarni G, Norman PJ, Pooler LC, Reiner AP, Romm J, Sabatti C, Sandoval K, Sheng X, Stahl EA, Stram DO, Thornton TA, Wassel CL, Wilkens LR, Winkler CA, Yoneyama S, Buyske S, Haiman CA, Kooperberg C, Le Marchand L, Loos RJF, Matise TC, North KE, Peters U, Kenny EE, Carlson CS.

Nature. 2019 Jun;570(7762):514-518. doi: 10.1038/s41586-019-1310-4. Epub 2019 Jun 19.

PMID:
31217584
2.

Diversity of KIR, HLA Class I, and Their Interactions in Seven Populations of Sub-Saharan Africans.

Nemat-Gorgani N, Guethlein LA, Henn BM, Norberg SJ, Chiaroni J, Sikora M, Quintana-Murci L, Mountain JL, Norman PJ, Parham P.

J Immunol. 2019 May 1;202(9):2636-2647. doi: 10.4049/jimmunol.1801586. Epub 2019 Mar 27.

PMID:
30918042
3.

Editorial overview: The history, geography and adaptation of human genes: A tribute to L. Luca Cavalli-Sforza.

Henn BM, Quintana-Murci L.

Curr Opin Genet Dev. 2018 Dec;53:iii-v. doi: 10.1016/j.gde.2018.11.004. No abstract available.

PMID:
30554668
4.

Rapid evolution of a skin-lightening allele in southern African KhoeSan.

Lin M, Siford RL, Martin AR, Nakagome S, Möller M, Hoal EG, Bustamante CD, Gignoux CR, Henn BM.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13324-13329. doi: 10.1073/pnas.1801948115. Epub 2018 Dec 10.

5.

Clarifying distinct models of modern human origins in Africa.

Henn BM, Steele TE, Weaver TD.

Curr Opin Genet Dev. 2018 Dec;53:148-156. doi: 10.1016/j.gde.2018.10.003. Epub 2018 Nov 10. Review.

PMID:
30423527
6.

No Evidence for Recent Selection at FOXP2 among Diverse Human Populations.

Atkinson EG, Audesse AJ, Palacios JA, Bobo DM, Webb AE, Ramachandran S, Henn BM.

Cell. 2018 Sep 6;174(6):1424-1435.e15. doi: 10.1016/j.cell.2018.06.048. Epub 2018 Aug 2.

7.

Did Our Species Evolve in Subdivided Populations across Africa, and Why Does It Matter?

Scerri EML, Thomas MG, Manica A, Gunz P, Stock JT, Stringer C, Grove M, Groucutt HS, Timmermann A, Rightmire GP, d'Errico F, Tryon CA, Drake NA, Brooks AS, Dennell RW, Durbin R, Henn BM, Lee-Thorp J, deMenocal P, Petraglia MD, Thompson JC, Scally A, Chikhi L.

Trends Ecol Evol. 2018 Aug;33(8):582-594. doi: 10.1016/j.tree.2018.05.005. Epub 2018 Jul 11.

8.

IMPUTOR: Phylogenetically Aware Software for Imputation of Errors in Next-Generation Sequencing.

Jobin M, Schurz H, Henn BM.

Genome Biol Evol. 2018 Apr 1;10(5):1248-1254. doi: 10.1093/gbe/evy088. Erratum in: Genome Biol Evol. 2018 Nov 1;10(11):2931.

9.

Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa.

Nemat-Gorgani N, Hilton HG, Henn BM, Lin M, Gignoux CR, Myrick JW, Werely CJ, Granka JM, Möller M, Hoal EG, Yawata M, Yawata N, Boelen L, Asquith B, Parham P, Norman PJ.

J Immunol. 2018 Apr 15;200(8):2640-2655. doi: 10.4049/jimmunol.1701780. Epub 2018 Mar 16.

10.

Localization of adaptive variants in human genomes using averaged one-dependence estimation.

Sugden LA, Atkinson EG, Fischer AP, Rong S, Henn BM, Ramachandran S.

Nat Commun. 2018 Feb 19;9(1):703. doi: 10.1038/s41467-018-03100-7.

11.

An Unexpectedly Complex Architecture for Skin Pigmentation in Africans.

Martin AR, Lin M, Granka JM, Myrick JW, Liu X, Sockell A, Atkinson EG, Werely CJ, Möller M, Sandhu MS, Kingsley DM, Hoal EG, Liu X, Daly MJ, Feldman MW, Gignoux CR, Bustamante CD, Henn BM.

Cell. 2017 Nov 30;171(6):1340-1353.e14. doi: 10.1016/j.cell.2017.11.015.

12.

Worldwide patterns of human epigenetic variation.

Carja O, MacIsaac JL, Mah SM, Henn BM, Kobor MS, Feldman MW, Fraser HB.

Nat Ecol Evol. 2017 Oct;1(10):1577-1583. doi: 10.1038/s41559-017-0299-z. Epub 2017 Aug 28.

PMID:
29185505
13.

Trends in DNA Methylation with Age Replicate Across Diverse Human Populations.

Gopalan S, Carja O, Fagny M, Patin E, Myrick JW, McEwen LM, Mah SM, Kobor MS, Froment A, Feldman MW, Quintana-Murci L, Henn BM.

Genetics. 2017 Jul;206(3):1659-1674. doi: 10.1534/genetics.116.195594. Epub 2017 May 22.

14.

A post-GWAS analysis of predicted regulatory variants and tuberculosis susceptibility.

Uren C, Henn BM, Franke A, Wittig M, van Helden PD, Hoal EG, Möller M.

PLoS One. 2017 Apr 6;12(4):e0174738. doi: 10.1371/journal.pone.0174738. eCollection 2017.

15.

Population genetic analysis of the DARC locus (Duffy) reveals adaptation from standing variation associated with malaria resistance in humans.

McManus KF, Taravella AM, Henn BM, Bustamante CD, Sikora M, Cornejo OE.

PLoS Genet. 2017 Mar 10;13(3):e1006560. doi: 10.1371/journal.pgen.1006560. eCollection 2017 Mar.

16.

Population structure and infectious disease risk in southern Africa.

Uren C, Möller M, van Helden PD, Henn BM, Hoal EG.

Mol Genet Genomics. 2017 Jun;292(3):499-509. doi: 10.1007/s00438-017-1296-2. Epub 2017 Feb 22. Review.

PMID:
28229227
17.

The Simons Genome Diversity Project: 300 genomes from 142 diverse populations.

Mallick S, Li H, Lipson M, Mathieson I, Gymrek M, Racimo F, Zhao M, Chennagiri N, Nordenfelt S, Tandon A, Skoglund P, Lazaridis I, Sankararaman S, Fu Q, Rohland N, Renaud G, Erlich Y, Willems T, Gallo C, Spence JP, Song YS, Poletti G, Balloux F, van Driem G, de Knijff P, Romero IG, Jha AR, Behar DM, Bravi CM, Capelli C, Hervig T, Moreno-Estrada A, Posukh OL, Balanovska E, Balanovsky O, Karachanak-Yankova S, Sahakyan H, Toncheva D, Yepiskoposyan L, Tyler-Smith C, Xue Y, Abdullah MS, Ruiz-Linares A, Beall CM, Di Rienzo A, Jeong C, Starikovskaya EB, Metspalu E, Parik J, Villems R, Henn BM, Hodoglugil U, Mahley R, Sajantila A, Stamatoyannopoulos G, Wee JT, Khusainova R, Khusnutdinova E, Litvinov S, Ayodo G, Comas D, Hammer MF, Kivisild T, Klitz W, Winkler CA, Labuda D, Bamshad M, Jorde LB, Tishkoff SA, Watkins WS, Metspalu M, Dryomov S, Sukernik R, Singh L, Thangaraj K, Pääbo S, Kelso J, Patterson N, Reich D.

Nature. 2016 Oct 13;538(7624):201-206. doi: 10.1038/nature18964. Epub 2016 Sep 21.

18.

Fine-Scale Human Population Structure in Southern Africa Reflects Ecogeographic Boundaries.

Uren C, Kim M, Martin AR, Bobo D, Gignoux CR, van Helden PD, Möller M, Hoal EG, Henn BM.

Genetics. 2016 Sep;204(1):303-14. doi: 10.1534/genetics.116.187369. Epub 2016 Jul 29.

19.

Population and Evolutionary Genomics of Amblyomma americanum, an Expanding Arthropod Disease Vector.

Monzón JD, Atkinson EG, Henn BM, Benach JL.

Genome Biol Evol. 2016 May 12;8(5):1351-60. doi: 10.1093/gbe/evw080.

20.

Worldwide variation in hip fracture incidence weakly aligns with genetic divergence between populations.

Wallace IJ, Botigué LR, Lin M, Smaers JB, Henn BM, Grine FE.

Osteoporos Int. 2016 Sep;27(9):2867-2872. doi: 10.1007/s00198-016-3591-x. Epub 2016 Apr 18.

PMID:
27091742
21.

Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.

Henn BM, Botigué LR, Peischl S, Dupanloup I, Lipatov M, Maples BK, Martin AR, Musharoff S, Cann H, Snyder MP, Excoffier L, Kidd JM, Bustamante CD.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):E440-9. doi: 10.1073/pnas.1510805112. Epub 2015 Dec 28.

22.

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

Hilton HG, Norman PJ, Nemat-Gorgani N, Goyos A, Hollenbach JA, Henn BM, Gignoux CR, Guethlein LA, Parham P.

PLoS Genet. 2015 Aug 20;11(8):e1005439. doi: 10.1371/journal.pgen.1005439. eCollection 2015 Aug.

23.

Estimating the mutation load in human genomes.

Henn BM, Botigué LR, Bustamante CD, Clark AG, Gravel S.

Nat Rev Genet. 2015 Jun;16(6):333-43. doi: 10.1038/nrg3931. Epub 2015 May 12. Review.

24.

Ancient human genomes suggest three ancestral populations for present-day Europeans.

Lazaridis I, Patterson N, Mittnik A, Renaud G, Mallick S, Kirsanow K, Sudmant PH, Schraiber JG, Castellano S, Lipson M, Berger B, Economou C, Bollongino R, Fu Q, Bos KI, Nordenfelt S, Li H, de Filippo C, Prüfer K, Sawyer S, Posth C, Haak W, Hallgren F, Fornander E, Rohland N, Delsate D, Francken M, Guinet JM, Wahl J, Ayodo G, Babiker HA, Bailliet G, Balanovska E, Balanovsky O, Barrantes R, Bedoya G, Ben-Ami H, Bene J, Berrada F, Bravi CM, Brisighelli F, Busby GB, Cali F, Churnosov M, Cole DE, Corach D, Damba L, van Driem G, Dryomov S, Dugoujon JM, Fedorova SA, Gallego Romero I, Gubina M, Hammer M, Henn BM, Hervig T, Hodoglugil U, Jha AR, Karachanak-Yankova S, Khusainova R, Khusnutdinova E, Kittles R, Kivisild T, Klitz W, Kučinskas V, Kushniarevich A, Laredj L, Litvinov S, Loukidis T, Mahley RW, Melegh B, Metspalu E, Molina J, Mountain J, Näkkäläjärvi K, Nesheva D, Nyambo T, Osipova L, Parik J, Platonov F, Posukh O, Romano V, Rothhammer F, Rudan I, Ruizbakiev R, Sahakyan H, Sajantila A, Salas A, Starikovskaya EB, Tarekegn A, Toncheva D, Turdikulova S, Uktveryte I, Utevska O, Vasquez R, Villena M, Voevoda M, Winkler CA, Yepiskoposyan L, Zalloua P, Zemunik T, Cooper A, Capelli C, Thomas MG, Ruiz-Linares A, Tishkoff SA, Singh L, Thangaraj K, Villems R, Comas D, Sukernik R, Metspalu M, Meyer M, Eichler EE, Burger J, Slatkin M, Pääbo S, Kelso J, Reich D, Krause J.

Nature. 2014 Sep 18;513(7518):409-13. doi: 10.1038/nature13673.

25.

Transcriptome sequencing from diverse human populations reveals differentiated regulatory architecture.

Martin AR, Costa HA, Lappalainen T, Henn BM, Kidd JM, Yee MC, Grubert F, Cann HM, Snyder M, Montgomery SB, Bustamante CD.

PLoS Genet. 2014 Aug 14;10(8):e1004549. doi: 10.1371/journal.pgen.1004549. eCollection 2014 Aug.

26.

Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe.

Sikora M, Carpenter ML, Moreno-Estrada A, Henn BM, Underhill PA, Sánchez-Quinto F, Zara I, Pitzalis M, Sidore C, Busonero F, Maschio A, Angius A, Jones C, Mendoza-Revilla J, Nekhrizov G, Dimitrova D, Theodossiev N, Harkins TT, Keller A, Maixner F, Zink A, Abecasis G, Sanna S, Cucca F, Bustamante CD.

PLoS Genet. 2014 May 8;10(5):e1004353. doi: 10.1371/journal.pgen.1004353. eCollection 2014 May.

27.

Exome capture from saliva produces high quality genomic and metagenomic data.

Kidd JM, Sharpton TJ, Bobo D, Norman PJ, Martin AR, Carpenter ML, Sikora M, Gignoux CR, Nemat-Gorgani N, Adams A, Guadalupe M, Guo X, Feng Q, Li Y, Liu X, Parham P, Hoal EG, Feldman MW, Pollard KS, Wall JD, Bustamante CD, Henn BM.

BMC Genomics. 2014 Apr 4;15:262. doi: 10.1186/1471-2164-15-262.

28.

A panel of ancestry informative markers for the complex five-way admixed South African coloured population.

Daya M, van der Merwe L, Galal U, Möller M, Salie M, Chimusa ER, Galanter JM, van Helden PD, Henn BM, Gignoux CR, Hoal E.

PLoS One. 2013 Dec 20;8(12):e82224. doi: 10.1371/journal.pone.0082224. eCollection 2013.

29.

Determining ancestry proportions in complex admixture scenarios in South Africa using a novel proxy ancestry selection method.

Chimusa ER, Daya M, Möller M, Ramesar R, Henn BM, van Helden PD, Mulder NJ, Hoal EG.

PLoS One. 2013 Sep 16;8(9):e73971. doi: 10.1371/journal.pone.0073971. eCollection 2013.

30.
31.

Sequencing Y chromosomes resolves discrepancy in time to common ancestor of males versus females.

Poznik GD, Henn BM, Yee MC, Sliwerska E, Euskirchen GM, Lin AA, Snyder M, Quintana-Murci L, Kidd JM, Underhill PA, Bustamante CD.

Science. 2013 Aug 2;341(6145):562-5. doi: 10.1126/science.1237619.

32.

Gene flow from North Africa contributes to differential human genetic diversity in southern Europe.

Botigué LR, Henn BM, Gravel S, Maples BK, Gignoux CR, Corona E, Atzmon G, Burns E, Ostrer H, Flores C, Bertranpetit J, Comas D, Bustamante CD.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11791-6. doi: 10.1073/pnas.1306223110. Epub 2013 Jun 3.

33.

The great human expansion.

Henn BM, Cavalli-Sforza LL, Feldman MW.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17758-64. doi: 10.1073/pnas.1212380109. Epub 2012 Oct 17.

34.

The genetic prehistory of southern Africa.

Pickrell JK, Patterson N, Barbieri C, Berthold F, Gerlach L, Güldemann T, Kure B, Mpoloka SW, Nakagawa H, Naumann C, Lipson M, Loh PR, Lachance J, Mountain J, Bustamante CD, Berger B, Tishkoff SA, Henn BM, Stoneking M, Reich D, Pakendorf B.

Nat Commun. 2012;3:1143. doi: 10.1038/ncomms2140.

35.

Limited evidence for classic selective sweeps in African populations.

Granka JM, Henn BM, Gignoux CR, Kidd JM, Bustamante CD, Feldman MW.

Genetics. 2012 Nov;192(3):1049-64. doi: 10.1534/genetics.112.144071. Epub 2012 Sep 7.

36.

North African Jewish and non-Jewish populations form distinctive, orthogonal clusters.

Campbell CL, Palamara PF, Dubrovsky M, Botigué LR, Fellous M, Atzmon G, Oddoux C, Pearlman A, Hao L, Henn BM, Burns E, Bustamante CD, Comas D, Friedman E, Pe'er I, Ostrer H.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13865-70. doi: 10.1073/pnas.1204840109. Epub 2012 Aug 6.

37.

Cryptic distant relatives are common in both isolated and cosmopolitan genetic samples.

Henn BM, Hon L, Macpherson JM, Eriksson N, Saxonov S, Pe'er I, Mountain JL.

PLoS One. 2012;7(4):e34267. doi: 10.1371/journal.pone.0034267. Epub 2012 Apr 3.

38.

Genomic ancestry of North Africans supports back-to-Africa migrations.

Henn BM, Botigué LR, Gravel S, Wang W, Brisbin A, Byrnes JK, Fadhlaoui-Zid K, Zalloua PA, Moreno-Estrada A, Bertranpetit J, Bustamante CD, Comas D.

PLoS Genet. 2012 Jan;8(1):e1002397. doi: 10.1371/journal.pgen.1002397. Epub 2012 Jan 12.

39.

Demographic history and rare allele sharing among human populations.

Gravel S, Henn BM, Gutenkunst RN, Indap AR, Marth GT, Clark AG, Yu F, Gibbs RA; 1000 Genomes Project, Bustamante CD.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11983-8. doi: 10.1073/pnas.1019276108. Epub 2011 Jul 5.

40.

Rapid, global demographic expansions after the origins of agriculture.

Gignoux CR, Henn BM, Mountain JL.

Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6044-9. doi: 10.1073/pnas.0914274108. Epub 2011 Mar 28.

41.

Hunter-gatherer genomic diversity suggests a southern African origin for modern humans.

Henn BM, Gignoux CR, Jobin M, Granka JM, Macpherson JM, Kidd JM, Rodríguez-Botigué L, Ramachandran S, Hon L, Brisbin A, Lin AA, Underhill PA, Comas D, Kidd KK, Norman PJ, Parham P, Bustamante CD, Mountain JL, Feldman MW.

Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5154-62. doi: 10.1073/pnas.1017511108. Epub 2011 Mar 7.

42.

Human origins: Shadows of early migrations.

Bustamante CD, Henn BM.

Nature. 2010 Dec 23;468(7327):1044-5. doi: 10.1038/4681044a. No abstract available.

PMID:
21179156
43.

Fine-scale population structure and the era of next-generation sequencing.

Henn BM, Gravel S, Moreno-Estrada A, Acevedo-Acevedo S, Bustamante CD.

Hum Mol Genet. 2010 Oct 15;19(R2):R221-6. doi: 10.1093/hmg/ddq403. Epub 2010 Sep 28. Review.

44.

The emergence of Y-chromosome haplogroup J1e among Arabic-speaking populations.

Chiaroni J, King RJ, Myres NM, Henn BM, Ducourneau A, Mitchell MJ, Boetsch G, Sheikha I, Lin AA, Nik-Ahd M, Ahmad J, Lattanzi F, Herrera RJ, Ibrahim ME, Brody A, Semino O, Kivisild T, Underhill PA.

Eur J Hum Genet. 2010 Mar;18(3):348-53. doi: 10.1038/ejhg.2009.166. Epub 2009 Oct 14.

45.

Characterizing the time dependency of human mitochondrial DNA mutation rate estimates.

Henn BM, Gignoux CR, Feldman MW, Mountain JL.

Mol Biol Evol. 2009 Jan;26(1):217-30. doi: 10.1093/molbev/msn244. Epub 2008 Nov 4. Erratum in: Mol Biol Evol. 2009 Mar;26(3):713.

PMID:
18984905
46.

Y-chromosomal evidence of a pastoralist migration through Tanzania to southern Africa.

Henn BM, Gignoux C, Lin AA, Oefner PJ, Shen P, Scozzari R, Cruciani F, Tishkoff SA, Mountain JL, Underhill PA.

Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10693-8. doi: 10.1073/pnas.0801184105. Epub 2008 Aug 4.

47.

History of click-speaking populations of Africa inferred from mtDNA and Y chromosome genetic variation.

Tishkoff SA, Gonder MK, Henn BM, Mortensen H, Knight A, Gignoux C, Fernandopulle N, Lema G, Nyambo TB, Ramakrishnan U, Reed FA, Mountain JL.

Mol Biol Evol. 2007 Oct;24(10):2180-95. Epub 2007 Jul 26.

PMID:
17656633
48.

African Y chromosome and mtDNA divergence provides insight into the history of click languages.

Knight A, Underhill PA, Mortensen HM, Zhivotovsky LA, Lin AA, Henn BM, Louis D, Ruhlen M, Mountain JL.

Curr Biol. 2003 Mar 18;13(6):464-73. Erratum in: Curr Biol. 2003 Apr 15;13(8):705.

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