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Items: 1 to 50 of 99

1.

TcR-induced regulated secretion leads to surface expression of CTLA-4 in CD4+CD25+ T cells.

Catalfamo M, Tai X, Karpova T, McNally J, Henkart PA.

Immunology. 2008 Sep;125(1):70-9. doi: 10.1111/j.1365-2567.2008.02822.x. Epub 2008 Apr 4.

2.

Granzyme B activity in target cells detects attack by cytotoxic lymphocytes.

Packard BZ, Telford WG, Komoriya A, Henkart PA.

J Immunol. 2007 Sep 15;179(6):3812-20.

3.

Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8(+) T-cell response.

Fann M, Godlove JM, Catalfamo M, Wood WH 3rd, Chrest FJ, Chun N, Granger L, Wersto R, Madara K, Becker K, Henkart PA, Weng NP.

Blood. 2006 Nov 15;108(10):3363-70. Epub 2006 Jul 25.

4.

Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis.

Bielekova B, Catalfamo M, Reichert-Scrivner S, Packer A, Cerna M, Waldmann TA, McFarland H, Henkart PA, Martin R.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5941-6. Epub 2006 Apr 3.

5.
6.

Do cytotoxic lymphocytes kill via reactive oxygen species?

Williams MS, Henkart PA.

Immunity. 2005 Mar;22(3):272-4.

7.

CD8+ effector cells.

Henkart PA, Catalfamo M.

Adv Immunol. 2004;83:233-52. Review. No abstract available.

PMID:
15135633
8.

Human CD8+ T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation.

Catalfamo M, Karpova T, McNally J, Costes SV, Lockett SJ, Bos E, Peters PJ, Henkart PA.

Immunity. 2004 Feb;20(2):219-30.

9.

Perforin and the granule exocytosis cytotoxicity pathway.

Catalfamo M, Henkart PA.

Curr Opin Immunol. 2003 Oct;15(5):522-7. Review.

PMID:
14499260
10.

IL-15 is a growth factor and an activator of CD8 memory T cells.

Weng NP, Liu K, Catalfamo M, Li Y, Henkart PA.

Ann N Y Acad Sci. 2002 Dec;975:46-56. Review.

PMID:
12538153
11.

Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation.

Balaji KN, Schaschke N, Machleidt W, Catalfamo M, Henkart PA.

J Exp Med. 2002 Aug 19;196(4):493-503.

12.

Regulation of leukemic cell adhesion, proliferation, and survival by beta-catenin.

Chung EJ, Hwang SG, Nguyen P, Lee S, Kim JS, Kim JW, Henkart PA, Bottaro DP, Soon L, Bonvini P, Lee SJ, Karp JE, Oh HJ, Rubin JS, Trepel JB.

Blood. 2002 Aug 1;100(3):982-90.

PMID:
12130512
13.

IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells.

Liu K, Catalfamo M, Li Y, Henkart PA, Weng NP.

Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6192-7. Epub 2002 Apr 23.

14.

Caspase 8 activity in membrane blebs after anti-Fas ligation.

Packard BZ, Komoriya A, Brotz TM, Henkart PA.

J Immunol. 2001 Nov 1;167(9):5061-6.

15.

Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice.

Haddad EK, Wu X, Hammer JA 3rd, Henkart PA.

J Cell Biol. 2001 Feb 19;152(4):835-42.

16.

Beta-chemokines inhibit activation-induced death of lymphocytes from HIV-infected individuals.

Pinto LA, Williams MS, Dolan MJ, Henkart PA, Shearer GM.

Eur J Immunol. 2000 Jul;30(7):2048-55.

17.

Assessment of caspase activities in intact apoptotic thymocytes using cell-permeable fluorogenic caspase substrates.

Komoriya A, Packard BZ, Brown MJ, Wu ML, Henkart PA.

J Exp Med. 2000 Jun 5;191(11):1819-28.

18.

Posttranslational regulation of the retinoblastoma gene family member p107 by calpain protease.

Jang JS, Lee SJ, Choi YH, Nguyen PM, Lee J, Hwang SG, Wu ML, Takano E, Maki M, Henkart PA, Trepel JB.

Oncogene. 1999 Mar 11;18(10):1789-96.

19.

Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death.

Williams MS, Noguchi S, Henkart PA, Osawa Y.

J Immunol. 1998 Dec 15;161(12):6526-31.

20.

Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells.

Bonfoco E, Stuart PM, Brunner T, Lin T, Griffith TS, Gao Y, Nakajima H, Henkart PA, Ferguson TA, Green DR.

Immunity. 1998 Nov;9(5):711-20.

22.

Caspase dependence of target cell damage induced by cytotoxic lymphocytes.

Sarin A, Haddad EK, Henkart PA.

J Immunol. 1998 Sep 15;161(6):2810-6.

23.

Regulation of cyclin D1 by calpain protease.

Choi YH, Lee SJ, Nguyen P, Jang JS, Lee J, Wu ML, Takano E, Maki M, Henkart PA, Trepel JB.

J Biol Chem. 1997 Nov 7;272(45):28479-84.

24.

Functional cleavage of the common cytokine receptor gamma chain (gammac) by calpain.

Noguchi M, Sarin A, Aman MJ, Nakajima H, Shores EW, Henkart PA, Leonard WJ.

Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11534-9.

25.

Do CTL kill target cells by inducing apoptosis?

Henkart PA, Williams MS, Zacharchuk CM, Sarin A.

Semin Immunol. 1997 Apr;9(2):135-44. Review.

PMID:
9194224
26.

CTL effector functions.

Henkart PA.

Semin Immunol. 1997 Apr;9(2):85-6. Review. No abstract available.

PMID:
9194218
27.

Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases.

Sarin A, Williams MS, Alexander-Miller MA, Berzofsky JA, Zacharchuk CM, Henkart PA.

Immunity. 1997 Feb;6(2):209-15.

29.

Role of reactive oxygen intermediates in TCR-induced death of T cell blasts and hybridomas.

Williams MS, Henkart PA.

J Immunol. 1996 Sep 15;157(6):2395-402.

PMID:
8805638
30.

Antigen-stimulated apoptotic T-cell death in HIV infection is selective for CD4+ T cells, modulated by cytokines and effected by lymphotoxin.

Clerici M, Sarin A, Berzofsky JA, Landay AL, Kessler HA, Hashemi F, Hendrix CW, Blatt SP, Rusnak J, Dolan MJ, Coffman RL, Henkart PA, Shearer GM.

AIDS. 1996 Jun;10(6):603-11.

PMID:
8780814
31.

Apoptosis: mitochondria resurrected?

Henkart PA, Grinstein S.

J Exp Med. 1996 Apr 1;183(4):1293-5. No abstract available.

32.

ICE family proteases: mediators of all apoptotic cell death?

Henkart PA.

Immunity. 1996 Mar;4(3):195-201. Review. No abstract available.

33.
34.

Cytotoxic effect of TNF and lymphotoxin on T lymphoblasts.

Sarin A, Conan-Cibotti M, Henkart PA.

J Immunol. 1995 Oct 15;155(8):3716-8.

PMID:
7561073
35.

A protease-dependent TCR-induced death pathway in mature lymphocytes.

Sarin A, Nakajima H, Henkart PA.

J Immunol. 1995 Jun 1;154(11):5806-12.

PMID:
7751630
36.

Apoptosis: O death, where is thy sting?

Henkart PA.

J Immunol. 1995 May 15;154(10):4905-8. Review. No abstract available.

PMID:
7730603
37.

The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity.

Nakajima H, Golstein P, Henkart PA.

J Exp Med. 1995 May 1;181(5):1905-9.

39.

Cytokines in immune regulation/pathogenesis in HIV infection.

Shearer GM, Clerici M, Sarin A, Berzofsky JA, Henkart PA.

Ciba Found Symp. 1995;195:142-7; discussion 147-53. Review.

PMID:
8724835
40.

Degranulating cytotoxic lymphocytes inflict multiple damage pathways on target cells.

Henkart PA, Williams MS, Nakajima H.

Curr Top Microbiol Immunol. 1995;198:75-93. Review. No abstract available.

PMID:
7774284
41.

Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis.

Clerici M, Sarin A, Coffman RL, Wynn TA, Blatt SP, Hendrix CW, Wolf SF, Shearer GM, Henkart PA.

Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):11811-5.

42.

Apoptotic cell death induced by intracellular proteolysis.

Williams MS, Henkart PA.

J Immunol. 1994 Nov 1;153(9):4247-55.

PMID:
7930626
43.

Cytotoxic lymphocytes. Two ways to kill target cells.

Henkart PA, Sitkovsky MV.

Curr Biol. 1994 Oct 1;4(10):923-5.

PMID:
7531594
44.

Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules.

Henkart PA.

Immunity. 1994 Aug;1(5):343-6. Review. No abstract available.

PMID:
7882166
45.

Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors.

Sarin A, Clerici M, Blatt SP, Hendrix CW, Shearer GM, Henkart PA.

J Immunol. 1994 Jul 15;153(2):862-72.

PMID:
8021517
46.
48.
49.

Clonal deletion of postthymic T cells: veto cells kill precursor cytotoxic T lymphocytes.

Hiruma K, Nakamura H, Henkart PA, Gress RE.

J Exp Med. 1992 Mar 1;175(3):863-8.

50.

Characterization of non-lytic cytolysin-membrane intermediates.

Kuta AE, Bashford CL, Pasternak CA, Reynolds CW, Henkart PA.

Mol Immunol. 1991 Nov;28(11):1263-70.

PMID:
1961199

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