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Burden of treatment in the face of childhood cancer: A quantitative study using medical records of deceased children.

Rost M, Wangmo T, Rakic M, Acheson E, Rischewski J, Hengartner H, Kühne T, Elger BS.

Eur J Cancer Care (Engl). 2018 Nov;27(6):e12879. doi: 10.1111/ecc.12879. Epub 2018 Jul 24.


Parents' and Physicians' Perceptions of Children's Participation in Decision-making in Paediatric Oncology: A Quantitative Study.

Rost M, Wangmo T, Niggli F, Hartmann K, Hengartner H, Ansari M, Brazzola P, Rischewski J, Beck-Popovic M, Kühne T, Elger BS.

J Bioeth Inq. 2017 Dec;14(4):555-565. doi: 10.1007/s11673-017-9813-x. Epub 2017 Oct 11.


Patients with Bernard-Soulier syndrome and different severity of the bleeding phenotype.

Boeckelmann D, Hengartner H, Greinacher A, Nowak-Göttl U, Sachs UJ, Peter K, Sandrock-Lang K, Zieger B.

Blood Cells Mol Dis. 2017 Sep;67:69-74. doi: 10.1016/j.bcmd.2017.01.010. Epub 2017 Jan 22.


Participation in pediatric oncology: views of child and adolescent patients.

Ruhe KM, Badarau DO, Brazzola P, Hengartner H, Elger BS, Wangmo T; Swiss Pediatric Oncology Group (SPOG).

Psychooncology. 2016 Sep;25(9):1036-42. doi: 10.1002/pon.4053. Epub 2015 Dec 17.


Space-time clustering of childhood cancers in Switzerland: A nationwide study.

Kreis C, Grotzer M, Hengartner H, Spycher BD; Swiss Paediatric Oncology Group; Swiss National Cohort Study Group.

Int J Cancer. 2016 May 1;138(9):2127-35. doi: 10.1002/ijc.29955. Epub 2016 Jan 8. Erratum in: Int J Cancer. 2017 Mar 15;140(6):E2-E12.


Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

Lang PA, Xu HC, Grusdat M, McIlwain DR, Pandyra AA, Harris IS, Shaabani N, Honke N, Maney SK, Lang E, Pozdeev VI, Recher M, Odermatt B, Brenner D, Häussinger D, Ohashi PS, Hengartner H, Zinkernagel RM, Mak TW, Lang KS.

Cell Death Differ. 2013 Apr;20(4):649-58. doi: 10.1038/cdd.2012.167. Epub 2013 Jan 18.


Alcohol consumption and binge drinking in young adult childhood cancer survivors.

Rebholz CE, Kuehni CE, Strippoli MP, Rueegg CS, Michel G, Hengartner H, Bergstraesser E, von der Weid NX; Swiss Pediatric Oncology Group (SPOG).

Pediatr Blood Cancer. 2012 Feb;58(2):256-64. doi: 10.1002/pbc.23289. Epub 2011 Aug 29.


X-ray structure of the arenavirus glycoprotein GP2 in its postfusion hairpin conformation.

Igonet S, Vaney MC, Vonrhein C, Bricogne G, Stura EA, Hengartner H, Eschli B, Rey FA.

Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):19967-72. doi: 10.1073/pnas.1108910108. Epub 2011 Nov 28. Erratum in: Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12156. Vonhrein, Clemens [corrected to Vonrhein, Clemens].


A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3.

Verschoor A, Neuenhahn M, Navarini AA, Graef P, Plaumann A, Seidlmeier A, Nieswandt B, Massberg S, Zinkernagel RM, Hengartner H, Busch DH.

Nat Immunol. 2011 Oct 30;12(12):1194-201. doi: 10.1038/ni.2140.


Childhood cancer and nuclear power plants in Switzerland: a census-based cohort study.

Spycher BD, Feller M, Zwahlen M, Röösli M, von der Weid NX, Hengartner H, Egger M, Kuehni CE; Swiss Paediatric Oncology Group; Swiss National Cohort Study Group.

Int J Epidemiol. 2011 Oct;40(5):1247-60. doi: 10.1093/ije/dyr115. Epub 2011 Jul 12.


Tissue macrophages suppress viral replication and prevent severe immunopathology in an interferon-I-dependent manner in mice.

Lang PA, Recher M, Honke N, Scheu S, Borkens S, Gailus N, Krings C, Meryk A, Kulawik A, Cervantes-Barragan L, Van Rooijen N, Kalinke U, Ludewig B, Hengartner H, Harris N, Häussinger D, Ohashi PS, Zinkernagel RM, Lang KS.

Hepatology. 2010 Jul;52(1):25-32. doi: 10.1002/hep.23640.


Long-lasting immunity by early infection of maternal-antibody-protected infants.

Navarini AA, Krzyzowska M, Lang KS, Horvath E, Hengartner H, Niemialtowski MG, Zinkernagel RM.

Eur J Immunol. 2010 Jan;40(1):113-6. doi: 10.1002/eji.200939371.


Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections.

Navarini AA, Lang KS, Verschoor A, Recher M, Zinkernagel AS, Nizet V, Odermatt B, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7107-12. doi: 10.1073/pnas.0901162106. Epub 2009 Apr 7.


Non-classical karyotypic features in relapsed childhood B-cell precursor acute lymphoblastic leukemia.

Wehrli LA, Braun J, Buetti LN, Hagleitner N, Hengartner H, Kühne T, Lüer S, Ozsahin H, Popovic MB, Niggli FK, Betts DR, Bourquin JP.

Cancer Genet Cytogenet. 2009 Feb;189(1):29-36. doi: 10.1016/j.cancergencyto.2008.10.002.


Recombination of retrotransposon and exogenous RNA virus results in nonretroviral cDNA integration.

Geuking MB, Weber J, Dewannieux M, Gorelik E, Heidmann T, Hengartner H, Zinkernagel RM, Hangartner L.

Science. 2009 Jan 16;323(5912):393-6. doi: 10.1126/science.1167375.


Polyclonal and specific antibodies mediate protective immunity against enteric helminth infection.

McCoy KD, Stoel M, Stettler R, Merky P, Fink K, Senn BM, Schaer C, Massacand J, Odermatt B, Oettgen HC, Zinkernagel RM, Bos NA, Hengartner H, Macpherson AJ, Harris NL.

Cell Host Microbe. 2008 Oct 16;4(4):362-73. doi: 10.1016/j.chom.2008.08.014.


Aggravation of viral hepatitis by platelet-derived serotonin.

Lang PA, Contaldo C, Georgiev P, El-Badry AM, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Merkler D, Odermatt B, Bader M, Graf R, Clavien PA, Hegazy AN, Löhning M, Harris NL, Ohashi PS, Hengartner H, Zinkernagel RM, Lang KS.

Nat Med. 2008 Jul;14(7):756-61. doi: 10.1038/nm1780. Epub 2008 May 30.


Compound heterozygosity for Hb S [beta6(A3)GluVal, GAG-->GTG] and a new thalassemic mutation [beta132(H10)Lys-->term, AAA-->TAA] detected in a family from West Africa.

Frischknecht H, Troxler H, Greiner J, Hengartner H, Dutly F.

Hemoglobin. 2008;32(3):309-13. doi: 10.1080/03630260701758866.


Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors.

Löhning M, Hegazy AN, Pinschewer DD, Busse D, Lang KS, Höfer T, Radbruch A, Zinkernagel RM, Hengartner H.

J Exp Med. 2008 Jan 21;205(1):53-61. doi: 10.1084/jem.20071855. Epub 2008 Jan 14.


Long-term maternal imprinting of the specific B cell repertoire by maternal antibodies.

Fink K, Zellweger R, Weber J, Manjarrez-Orduno N, Holdener M, Senn BM, Hengartner H, Zinkernagel RM, Macpherson AJ.

Eur J Immunol. 2008 Jan;38(1):90-101.


Characterization of high-hyperdiploidy in childhood acute lymphoblastic leukemia with gain of a single chromosome 21.

Brown A, Niggli F, Hengartner H, Caflisch U, Nobile L, Kuhne T, Angst R, Bourquin JP, Betts D.

Leuk Lymphoma. 2007 Dec;48(12):2457-60. No abstract available.


"Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses.

Lang KS, Hegazy AN, Lang PA, Eschli B, Löhning M, Hengartner H, Zinkernagel RM, Recher M.

PLoS One. 2007 Nov 14;2(11):e1162.


Extralymphatic virus sanctuaries as a consequence of potent T-cell activation.

Recher M, Lang KS, Navarini A, Hunziker L, Lang PA, Fink K, Freigang S, Georgiev P, Hangartner L, Zellweger R, Bergthaler A, Hegazy AN, Eschli B, Theocharides A, Jeker LT, Merkler D, Odermatt B, Hersberger M, Hengartner H, Zinkernagel RM.

Nat Med. 2007 Nov;13(11):1316-23. Epub 2007 Nov 4.


B cell activation state-governed formation of germinal centers following viral infection.

Fink K, Manjarrez-Orduño N, Schildknecht A, Weber J, Senn BM, Zinkernagel RM, Hengartner H.

J Immunol. 2007 Nov 1;179(9):5877-85.


Early antibodies specific for the neutralizing epitope on the receptor binding subunit of the lymphocytic choriomeningitis virus glycoprotein fail to neutralize the virus.

Eschli B, Zellweger RM, Wepf A, Lang KS, Quirin K, Weber J, Zinkernagel RM, Hengartner H.

J Virol. 2007 Nov;81(21):11650-7. Epub 2007 Aug 15.


A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8(+) T cell responses.

Freigang S, Eschli B, Harris N, Geuking M, Quirin K, Schrempf S, Zellweger R, Weber J, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13426-31. Epub 2007 Aug 8.


MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus.

Lang KS, Navarini AA, Recher M, Lang PA, Heikenwalder M, Stecher B, Bergthaler A, Odermatt B, Akira S, Honda K, Hengartner H, Zinkernagel RM.

Eur J Immunol. 2007 Sep;37(9):2434-40.


Loss of i(8)(q10) at relapse in two cases of childhood acute myeloid leukaemia.

Seppa L, Hengartner H, Leibundgut K, Kuhne T, Niggli FK, Betts DR.

Leuk Lymphoma. 2007 May;48(5):1045-7. No abstract available.


Identification and characterization of a novel antigen from the nematode Nippostrongylus brasiliensis recognized by specific IgE.

Pochanke V, Koller S, Dayer R, Hatak S, Ludewig B, Zinkernagel RM, Hengartner H, McCoy KD.

Eur J Immunol. 2007 May;37(5):1275-84.


The prognostic significance of cytogenetic aberrations in childhood acute myeloid leukaemia. A study of the Swiss Paediatric Oncology Group (SPOG).

Betts DR, Ammann RA, Hirt A, Hengartner H, Beck-Popovic M, Kuhne T, Nobile L, Caflisch U, Wacker P, Niggli FK.

Eur J Haematol. 2007 Jun;78(6):468-76. Epub 2007 Apr 5.


Dendritic cell-independent B cell activation during acute virus infection: a role for early CCR7-driven B-T helper cell collaboration.

Scandella E, Fink K, Junt T, Senn BM, Lattmann E, Förster R, Hengartner H, Ludewig B.

J Immunol. 2007 Feb 1;178(3):1468-76.


Parameters governing exhaustion of rare T cell-independent neutralizing IgM-producing B cells after LCMV infection.

Zellweger RM, Hangartner L, Weber J, Zinkernagel RM, Hengartner H.

Eur J Immunol. 2006 Dec;36(12):3175-85.


Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses.

Navarini AA, Recher M, Lang KS, Georgiev P, Meury S, Bergthaler A, Flatz L, Bille J, Landmann R, Odermatt B, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2006 Oct 17;103(42):15535-9. Epub 2006 Oct 9.


Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC.

Martinic MM, van den Broek MF, Rülicke T, Huber C, Odermatt B, Reith W, Horvath E, Zellweger R, Fink K, Recher M, Eschli B, Hengartner H, Zinkernagel RM.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14435-40. Epub 2006 Sep 18.


Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling.

Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, Heikenwalder M, Harris NL, Junt T, Odermatt B, Clavien PA, Pircher H, Akira S, Hengartner H, Zinkernagel RM.

J Clin Invest. 2006 Sep;116(9):2456-63.


Induction of IgE and allergic-type responses in fur mite-infested mice.

Pochanke V, Hatak S, Hengartner H, Zinkernagel RM, McCoy KD.

Eur J Immunol. 2006 Sep;36(9):2434-45.


Nonneutralizing antibodies binding to the surface glycoprotein of lymphocytic choriomeningitis virus reduce early virus spread.

Hangartner L, Zellweger RM, Giobbi M, Weber J, Eschli B, McCoy KD, Harris N, Recher M, Zinkernagel RM, Hengartner H.

J Exp Med. 2006 Aug 7;203(8):2033-42. Epub 2006 Jul 31.


Early type I interferon-mediated signals on B cells specifically enhance antiviral humoral responses.

Fink K, Lang KS, Manjarrez-Orduno N, Junt T, Senn BM, Holdener M, Akira S, Zinkernagel RM, Hengartner H.

Eur J Immunol. 2006 Aug;36(8):2094-105.


Natural IgE production in the absence of MHC Class II cognate help.

McCoy KD, Harris NL, Diener P, Hatak S, Odermatt B, Hangartner L, Senn BM, Marsland BJ, Geuking MB, Hengartner H, Macpherson AJ, Zinkernagel RM.

Immunity. 2006 Mar;24(3):329-39.


Antiviral antibody responses: the two extremes of a wide spectrum.

Hangartner L, Zinkernagel RM, Hengartner H.

Nat Rev Immunol. 2006 Mar;6(3):231-43. Review.


Microchimerism maintains deletion of the donor cell-specific CD8+ T cell repertoire.

Bonilla WV, Geuking MB, Aichele P, Ludewig B, Hengartner H, Zinkernagel RM.

J Clin Invest. 2006 Jan;116(1):156-62.


CXCR5-dependent seeding of follicular niches by B and Th cells augments antiviral B cell responses.

Junt T, Fink K, Förster R, Senn B, Lipp M, Muramatsu M, Zinkernagel RM, Ludewig B, Hengartner H.

J Immunol. 2005 Dec 1;175(11):7109-16.


Requirement for neutralizing antibodies to control bone marrow transplantation-associated persistent viral infection and to reduce immunopathology.

Lang KS, Recher M, Navarini AA, Freigang S, Harris NL, van den Broek M, Odermatt B, Hengartner H, Zinkernagel RM.

J Immunol. 2005 Oct 15;175(8):5524-31.


Responses to Cohn's discussion on the Zinkernagel-Hengartner 'Credo 2004'.

Zinkernagel R, Hengartner H.

Scand J Immunol. 2005 Sep;62(3):195-201. No abstract available.


Inverse correlation between IL-7 receptor expression and CD8 T cell exhaustion during persistent antigen stimulation.

Lang KS, Recher M, Navarini AA, Harris NL, Löhning M, Junt T, Probst HC, Hengartner H, Zinkernagel RM.

Eur J Immunol. 2005 Mar;35(3):738-45.


Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease.

Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM.

Nat Med. 2005 Feb;11(2):138-45. Epub 2005 Jan 16. Erratum in: Nat Med. 2005 Nov;11(11):1256.


Impact of CCR7 on priming and distribution of antiviral effector and memory CTL.

Junt T, Scandella E, Förster R, Krebs P, Krautwald S, Lipp M, Hengartner H, Ludewig B.

J Immunol. 2004 Dec 1;173(11):6684-93.


Port-A-Cath infections in children with cancer.

Hengartner H, Berger C, Nadal D, Niggli FK, Grotzer MA.

Eur J Cancer. 2004 Nov;40(16):2452-8. Review.


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