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Items: 1 to 50 of 384

1.

Sphingosine kinase 2 potentiates amyloid deposition but protects against hippocampal volume loss and demyelination in a mouse model of Alzheimer's disease.

Lei M, Teo JD, Song H, McEwen HP, Yup Lee J, Couttas TA, Duncan T, Chesworth R, Bertz J, Przybyla M, Van Eersel J, Heng B, Guillemin GJ, Ittner LM, Fath T, Garner B, Ittner A, Karl T, Don AS.

J Neurosci. 2019 Oct 21. pii: 0524-19. doi: 10.1523/JNEUROSCI.0524-19.2019. [Epub ahead of print]

PMID:
31641049
2.

Characterization and Comparison of Postnatal Rat Meniscus Stem Cells at Different Developmental Stages.

He S, Ruan D, Chen Y, Ran J, Chen X, Yin Z, Tang C, Huang J, Heng BC, Chen J, Chen W, Shen W, Ouyang H.

Stem Cells Transl Med. 2019 Oct 22. doi: 10.1002/sctm.19-0125. [Epub ahead of print]

3.

Postnatal Expression Patterns of Estrogen Receptor Subtypes and Choline Acetyltransferase in Different Regions of the Papez Circuit.

Wang YX, Zhu L, Li LX, Xu HN, Wang HG, An D, Heng B, Zhao Q, Liu YQ.

Dev Neurosci. 2019 Sep 19:1-9. doi: 10.1159/000502686. [Epub ahead of print]

PMID:
31536986
4.

Diverse effects of pulsed electrical stimulation on cells - with a focus on chondrocytes and cartilage regeneration.

Ning T, Zhang K, Heng BC, Ge Z.

Eur Cell Mater. 2019 Sep 3;38:79-93. doi: 10.22203/eCM.v038a07.

5.

Metformin inhibits Aβ25-35 -induced apoptotic cell death in SH-SY5Y cells.

Li LX, Liu MY, Jiang X, Xia ZH, Wang YX, An D, Wang HG, Heng B, Liu YQ.

Basic Clin Pharmacol Toxicol. 2019 Nov;125(5):439-449. doi: 10.1111/bcpt.13279. Epub 2019 Jul 9.

PMID:
31220411
6.

Understanding the Immunological Mechanisms of Mesenchymal Stem Cells in Allogeneic Transplantation: From the Aspect of Major Histocompatibility Complex Class I.

Wang Y, Tian M, Wang F, Heng BC, Zhou J, Cai Z, Liu H.

Stem Cells Dev. 2019 Sep 1;28(17):1141-1150. doi: 10.1089/scd.2018.0256. Epub 2019 Jul 31.

PMID:
31215341
7.

Genistein Inhibits Aβ25-35-Induced Neuronal Death with Changes in the Electrophysiological Properties of Voltage-Gated Sodium and Potassium Channels.

Wang YX, Xia ZH, Jiang X, Li LX, An D, Wang HG, Heng B, Liu YQ.

Cell Mol Neurobiol. 2019 Aug;39(6):809-822. doi: 10.1007/s10571-019-00680-w. Epub 2019 Apr 30.

PMID:
31037516
8.

EphrinB2/EphB4 Signaling Regulates DPSCs to Induce Sprouting Angiogenesis of Endothelial Cells.

Gong T, Xu J, Heng B, Qiu S, Yi B, Han Y, Lo ECM, Zhang C.

J Dent Res. 2019 Jul;98(7):803-812. doi: 10.1177/0022034519843886. Epub 2019 Apr 24.

PMID:
31017515
9.

Small molecules enhance neurogenic differentiation of dental-derived adult stem cells.

Heng BC, Jiang S, Yi B, Gong T, Lim LW, Zhang C.

Arch Oral Biol. 2019 Jun;102:26-38. doi: 10.1016/j.archoralbio.2019.03.024. Epub 2019 Mar 29.

PMID:
30954806
10.

Sema4D/PlexinB1 promotes endothelial differentiation of dental pulp stem cells via activation of AKT and ERK1/2 signaling.

Zou T, Jiang S, Dissanayaka WL, Heng BC, Xu J, Gong T, Huang X, Zhang C.

J Cell Biochem. 2019 Aug;120(8):13614-13624. doi: 10.1002/jcb.28635. Epub 2019 Apr 1.

PMID:
30937968
11.

Local Delivery of Silk-Cellulose Incorporated with Stromal Cell-Derived Factor-1α Functionally Improves the Uterus Repair.

Cai H, Wu B, Li Y, Liu Y, Shi L, Gong L, Xia Y, Heng BC, Wu H, Ouyang H, Zhu Z, Zou X.

Tissue Eng Part A. 2019 Nov;25(21-22):1514-1526. doi: 10.1089/ten.TEA.2018.0283. Epub 2019 Sep 3.

PMID:
30838933
12.

Is there scope for expanding the optometrist's scope of practice in Singapore? - A survey of optometrists, opticians in Singapore.

George PP, Yun OCS, Siow K, Saxena N, Heng BH, Car J, Lockwood C.

Cont Lens Anterior Eye. 2019 Jun;42(3):258-264. doi: 10.1016/j.clae.2019.02.008. Epub 2019 Feb 26.

PMID:
30819628
13.

Enhancement of the chondrogenic differentiation of mesenchymal stem cells and cartilage repair by ghrelin.

Fan L, Chen J, Tao Y, Heng BC, Yu J, Yang Z, Ge Z.

J Orthop Res. 2019 Jun;37(6):1387-1397. doi: 10.1002/jor.24224. Epub 2019 Feb 12.

PMID:
30644571
14.

Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor.

Engel M, Gee YS, Cross D, Maccarone A, Heng B, Hulme A, Smith G, Guillemin GJ, Stringer BW, Hyland CJT, Ooi L.

J Neurochem. 2019 May;149(4):535-550. doi: 10.1111/jnc.14655. Epub 2019 Feb 3.

15.

Effects of chronic diseases on health-related quality of life and self-rated health among three adult age groups.

Ge L, Ong R, Yap CW, Heng BH.

Nurs Health Sci. 2019 Jun;21(2):214-222. doi: 10.1111/nhs.12585. Epub 2018 Dec 10.

PMID:
30537214
16.

Protective Effects of Myxobacterial Extracts on Hydrogen Peroxide-induced Toxicity on Human Primary Astrocytes.

Dehhaghi M, Tan V, Heng B, Mohammadipanah F, Guillemin GJ.

Neuroscience. 2019 Feb 10;399:1-11. doi: 10.1016/j.neuroscience.2018.11.033. Epub 2018 Nov 26.

PMID:
30496822
17.

A collagen-coated sponge silk scaffold for functional meniscus regeneration.

Yan R, Chen Y, Gu Y, Tang C, Huang J, Hu Y, Zheng Z, Ran J, Heng B, Chen X, Yin Z, Chen W, Shen W, Ouyang H.

J Tissue Eng Regen Med. 2019 Feb;13(2):156-173. doi: 10.1002/term.2777. Epub 2019 Jan 4.

PMID:
30485706
18.

Lipoteichoic acid of Enterococcus faecalis inhibits osteoclastogenesis via transcription factor RBP-J.

Wang S, Heng BC, Qiu S, Deng J, Shun Pan Cheung G, Jin L, Zhao B, Zhang C.

Innate Immun. 2019 Jan;25(1):13-21. doi: 10.1177/1753425918812646. Epub 2018 Nov 21.

PMID:
30463464
19.

Genistein inhibits Aβ25-35 -induced SH-SY5Y cell damage by modulating the expression of apoptosis-related proteins and Ca2+ influx through ionotropic glutamate receptors.

Xu HN, Li LX, Wang YX, Wang HG, An D, Heng B, Liu YQ.

Phytother Res. 2019 Feb;33(2):431-441. doi: 10.1002/ptr.6239. Epub 2018 Nov 19.

PMID:
30450837
20.

Lifetime trajectory simulation of chronic disease progression and comorbidity development.

Zhu Z, Heng BH, Teow KL.

J Biomed Inform. 2018 Dec;88:29-36. doi: 10.1016/j.jbi.2018.11.002. Epub 2018 Nov 7.

PMID:
30414473
21.

The relationship between substrate topography and stem cell differentiation in the musculoskeletal system.

Huang J, Chen Y, Tang C, Fei Y, Wu H, Ruan D, Paul ME, Chen X, Yin Z, Heng BC, Chen W, Shen W.

Cell Mol Life Sci. 2019 Feb;76(3):505-521. doi: 10.1007/s00018-018-2945-2. Epub 2018 Nov 2. Review.

PMID:
30390116
22.

Neuroprotective Effect of Myxobacterial Extracts on Quinolinic Acid-Induced Toxicity in Primary Human Neurons.

Dehhaghi M, Tan V, Heng B, Braidy N, Mohammadipanah F, Guillemin GJ.

Neurotox Res. 2019 Feb;35(2):281-290. doi: 10.1007/s12640-018-9945-8. Epub 2018 Sep 28.

PMID:
30267267
23.

Health Technology Disinvestment in Singapore.

Lim BP, Heng BH, Tai HY, Tham L, Chua HC.

Ann Acad Med Singapore. 2018 Aug;47(8):338-344.

24.

The roles of inflammatory mediators and immunocytes in tendinopathy.

Tang C, Chen Y, Huang J, Zhao K, Chen X, Yin Z, Heng BC, Chen W, Shen W.

J Orthop Translat. 2018 Apr 14;14:23-33. doi: 10.1016/j.jot.2018.03.003. eCollection 2018 Jul. Review.

25.

Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation.

Shao J, Wang M, Yu G, Zhu S, Yu Y, Heng BC, Wu J, Ye H.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6722-E6730. doi: 10.1073/pnas.1802448115. Epub 2018 Jul 2.

26.

EphrinB2 signalling modulates the neural differentiation of human dental pulp stem cells.

Heng BC, Gong T, Xu J, Lim LW, Zhang C.

Biomed Rep. 2018 Aug;9(2):161-168. doi: 10.3892/br.2018.1108. Epub 2018 Jun 1.

27.

Sex differences in associations between multimorbidity and physical function domains among community-dwelling adults in Singapore.

Ge L, Yap CW, Heng BH.

PLoS One. 2018 May 14;13(5):e0197443. doi: 10.1371/journal.pone.0197443. eCollection 2018.

28.

SFRP1 Promoter Methylation and Renal Carcinoma Risk: A Systematic Review and Meta-Analysis.

Mo S, Su Z, Heng B, Chen W, Shi L, Du X, Lai C.

J Nippon Med Sch. 2018;85(2):78-86. doi: 10.1272/jnms.2018_85-13. Review.

29.

A comparison of food habits and prey preferences of Amur tiger (Panthera tigris altaica) at the southwest Primorskii Krai in Russia and Hunchun in China.

Gu J, Yu L, Hua Y, Ning Y, Heng B, Qi J, Long Z, Yao M, Huang C, Li Z, Lang J, Jiang G, Ma J.

Integr Zool. 2018 Sep;13(5):595-603. doi: 10.1111/1749-4877.12322.

PMID:
29722132
30.

Corrigendum to"Effects of compatibility of deproteinized antler cancellous bone with various bioactive factors on their osteogenic potential" [Biomaterials 34 (2013) 9103-9114].

Zhang X, Xu M, Song L, Wei Y, Lin Y, Liu W, Heng BC, Peng H, Wang Y, Deng X.

Biomaterials. 2018 Jul;170:136. doi: 10.1016/j.biomaterials.2018.04.018. Epub 2018 Apr 14. No abstract available.

PMID:
29665502
31.

Cepharanthine Prevents Estrogen Deficiency-Induced Bone Loss by Inhibiting Bone Resorption.

Zhou CH, Meng JH, Yang YT, Hu B, Hong JQ, Lv ZT, Chen K, Heng BC, Jiang GY, Zhu J, Cheng ZH, Zhang W, Cao L, Wang W, Shen WL, Yan SG, Wu HB.

Front Pharmacol. 2018 Mar 27;9:210. doi: 10.3389/fphar.2018.00210. eCollection 2018.

32.

Concise Review: Stem Cell Fate Guided By Bioactive Molecules for Tendon Regeneration.

Zhang YJ, Chen X, Li G, Chan KM, Heng BC, Yin Z, Ouyang HW.

Stem Cells Transl Med. 2018 May;7(5):404-414. doi: 10.1002/sctm.17-0206. Epub 2018 Mar 23. Review.

33.

Exogenous stromal derived factor-1 releasing silk scaffold combined with intra-articular injection of progenitor cells promotes bone-ligament-bone regeneration.

Hu Y, Ran J, Zheng Z, Jin Z, Chen X, Yin Z, Tang C, Chen Y, Huang J, Le H, Yan R, Zhu T, Wang J, Lin J, Xu K, Zhou Y, Zhang W, Cai Y, Dominique P, Heng BC, Chen W, Shen W, Ouyang HW.

Acta Biomater. 2018 Apr 15;71:168-183. doi: 10.1016/j.actbio.2018.02.019. Epub 2018 Mar 7.

PMID:
29524675
34.

Therapeutic effects of gefitinib-encapsulated thermosensitive injectable hydrogel in intervertebral disc degeneration.

Pan Z, Sun H, Xie B, Xia D, Zhang X, Yu D, Li J, Xu Y, Wang Z, Wu Y, Zhang X, Wang Y, Fu Q, Hu W, Yang Y, Bunpetch V, Shen W, Heng BC, Zhang S, Ouyang H.

Biomaterials. 2018 Apr;160:56-68. doi: 10.1016/j.biomaterials.2018.01.016. Epub 2018 Jan 11.

PMID:
29396379
35.

Prevalence of frailty and its association with depressive symptoms among older adults in Singapore.

Ge L, Yap CW, Heng BH.

Aging Ment Health. 2019 Mar;23(3):319-324. doi: 10.1080/13607863.2017.1416332. Epub 2018 Jan 16.

PMID:
29336608
36.

EphrinB2 signaling enhances osteogenic/odontogenic differentiation of human dental pulp stem cells.

Heng BC, Wang S, Gong T, Xu J, Yuan C, Zhang C.

Arch Oral Biol. 2018 Mar;87:62-71. doi: 10.1016/j.archoralbio.2017.12.014. Epub 2017 Dec 16.

PMID:
29272761
37.

Evaluation of an integrated primary care-led dementia shared care program in Singapore: An effectiveness and cost-effectiveness study.

Saxena N, George PP, Teo KW, Tan WS, Ng C, Heng BH, Yeo CYY, Anthony P, Tan C, Low KY, Wu V, Ali NB, Chong MS.

Geriatr Gerontol Int. 2018 Mar;18(3):479-486. doi: 10.1111/ggi.13196. Epub 2017 Nov 28.

PMID:
29193721
38.

Engrailed-2 promoter hyper-methylation is associated with its downregulation in clear cell renal cell carcinoma.

Lai CY, Yu GS, Xu Y, Wu X, Heng BL, Xue YJ, Su ZX.

Oncol Lett. 2017 Dec;14(6):6888-6894. doi: 10.3892/ol.2017.7000. Epub 2017 Sep 19.

39.

Sophocarpine attenuates wear particle-induced implant loosening by inhibiting osteoclastogenesis and bone resorption via suppression of the NF-κB signalling pathway in a rat model.

Zhou CH, Shi ZL, Meng JH, Hu B, Zhao CC, Yang YT, Yu W, Chen ZX, Heng BC, Parkman VA, Jiang S, Zhu HX, Wu HB, Shen WL, Yan SG.

Br J Pharmacol. 2018 Mar;175(6):859-876. doi: 10.1111/bph.14092. Epub 2018 Feb 14.

40.

Re-examining the sensitivity of HbA1c to screen for diabetes mellitus.

Yap CW, Ang YG, Quek TPL, Heng BH, Chew DEK.

J Diabetes. 2018 May;10(5):380-385. doi: 10.1111/1753-0407.12615. Epub 2017 Dec 11.

PMID:
29030996
41.

Inhibition of TGF-β Signaling in SHED Enhances Endothelial Differentiation.

Xu JG, Gong T, Wang YY, Zou T, Heng BC, Yang YQ, Zhang CF.

J Dent Res. 2018 Feb;97(2):218-225. doi: 10.1177/0022034517733741. Epub 2017 Oct 3.

42.

Medication adherence and glycemic control among newly diagnosed diabetes patients.

Lin LK, Sun Y, Heng BH, Chew DEK, Chong PN.

BMJ Open Diabetes Res Care. 2017 Jul 31;5(1):e000429. doi: 10.1136/bmjdrc-2017-000429. eCollection 2017.

43.

Social isolation, loneliness and their relationships with depressive symptoms: A population-based study.

Ge L, Yap CW, Ong R, Heng BH.

PLoS One. 2017 Aug 23;12(8):e0182145. doi: 10.1371/journal.pone.0182145. eCollection 2017.

44.

Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix.

Wang Y, Yu D, Liu Z, Zhou F, Dai J, Wu B, Zhou J, Heng BC, Zou XH, Ouyang H, Liu H.

Stem Cell Res Ther. 2017 Aug 14;8(1):189. doi: 10.1186/s13287-017-0632-0.

45.

Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine-2,3-dioxygenase-involved mechanism(s).

Guo F, Hu M, Huang D, Zhao Y, Heng B, Guillemin G, Lim CK, Hawthorne WJ, Yi S.

Xenotransplantation. 2017 Sep;24(5). doi: 10.1111/xen.12326. Epub 2017 Aug 2.

PMID:
28771838
46.

Delivery of epidermal growth factor receptor inhibitor via a customized collagen scaffold promotes meniscal defect regeneration in a rabbit model.

Pan Z, Wu Y, Zhang X, Fu Q, Li J, Yang Y, Yu D, Xu Y, Lu X, Sun H, Zhang X, Heng BC, Bunpetch V, Zhang S, Ouyang H.

Acta Biomater. 2017 Oct 15;62:210-221. doi: 10.1016/j.actbio.2017.07.008. Epub 2017 Jul 28.

PMID:
28757192
47.

Small molecule therapeutics for inflammation-associated chronic musculoskeletal degenerative diseases: Past, present and future.

Chen Y, Huang J, Tang C, Chen X, Yin Z, Heng BC, Chen W, Shen W.

Exp Cell Res. 2017 Oct 1;359(1):1-9. doi: 10.1016/j.yexcr.2017.07.027. Epub 2017 Jul 22. Review.

PMID:
28739444
48.

A Gelatin-sulfonated Silk Composite Scaffold based on 3D Printing Technology Enhances Skin Regeneration by Stimulating Epidermal Growth and Dermal Neovascularization.

Xiong S, Zhang X, Lu P, Wu Y, Wang Q, Sun H, Heng BC, Bunpetch V, Zhang S, Ouyang H.

Sci Rep. 2017 Jun 27;7(1):4288. doi: 10.1038/s41598-017-04149-y.

49.

Reconstructing Lineage Hierarchies of Mouse Uterus Epithelial Development Using Single-Cell Analysis.

Wu B, An C, Li Y, Yin Z, Gong L, Li Z, Liu Y, Heng BC, Zhang D, Ouyang H, Zou X.

Stem Cell Reports. 2017 Jul 11;9(1):381-396. doi: 10.1016/j.stemcr.2017.05.022. Epub 2017 Jun 15.

50.

PTH[1-34] improves the effects of core decompression in early-stage steroid-associated osteonecrosis model by enhancing bone repair and revascularization.

Zhou CH, Meng JH, Zhao CC, Ye CY, Zhu HX, Hu B, Heng BC, Shen Y, Lin T, Yang XB, Shi ZL, Shen WL, Yan SG.

PLoS One. 2017 May 31;12(5):e0178781. doi: 10.1371/journal.pone.0178781. eCollection 2017.

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