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Items: 1 to 50 of 411

1.

Naltrexone-bupropion (Mysimba®) in management of obesity: a systematic review and meta-analysis of unpublished clinical study reports.

Onakpoya IJ, Lee JJ, Mahtani KR, Aronson JK, Heneghan CJ.

Br J Clin Pharmacol. 2020 Jan 9. doi: 10.1111/bcp.14210. [Epub ahead of print] Review.

PMID:
31918448
2.

Does cranberry extract reduce antibiotic use for symptoms of acute uncomplicated urinary tract infections (CUTI)? Protocol for a feasibility study.

Gbinigie O, Allen J, Boylan AM, Hay A, Heneghan C, Moore M, Williams N, Butler C.

Trials. 2019 Dec 23;20(1):767. doi: 10.1186/s13063-019-3860-z.

3.

Impact of Changes to National Hypertension Guidelines on Hypertension Management and Outcomes in the United Kingdom.

Lay-Flurrie SL, Sheppard JP, Stevens RJ, Mallen C, Heneghan C, Hobbs FDR, Williams B, Mant J, McManus RJ.

Hypertension. 2020 Feb;75(2):356-364. doi: 10.1161/HYPERTENSIONAHA.119.13926. Epub 2019 Dec 23.

PMID:
31865798
4.

Medical Devices: Definition, Classification, and Regulatory Implications.

Aronson JK, Heneghan C, Ferner RE.

Drug Saf. 2019 Dec 16. doi: 10.1007/s40264-019-00878-3. [Epub ahead of print]

PMID:
31845212
5.

Withdrawn medicines included in the essential medicines lists of 136 countries.

Charles O, Onakpoya I, Benipal S, Woods H, Bali A, Aronson JK, Heneghan C, Persaud N.

PLoS One. 2019 Dec 2;14(12):e0225429. doi: 10.1371/journal.pone.0225429. eCollection 2019.

6.

Extending anticoagulation treatment for unprovoked venous thromboembolism.

Heneghan C, Aronson J.

BMJ Evid Based Med. 2019 Nov 26. pii: bmjebm-2019-111252. doi: 10.1136/bmjebm-2019-111252. [Epub ahead of print] No abstract available.

PMID:
31771946
7.

Self-monitoring of blood pressure in patients with hypertension related multi-morbidity: Systematic review and individual patient data meta-analysis.

Sheppard JP, Tucker KL, Davison WJ, Stevens R, Aekplakorn W, Bosworth HB, Bove A, Earle K, Godwin M, Green BB, Hebert P, Heneghan C, Hill N, Hobbs FDR, Kantola I, Kerry SM, Leiva A, Magid DJ, Mant J, Margolis KL, McKinstry B, McLaughlin MA, McNamara K, Omboni S, Ogedegbe O, Parati G, Varis J, Verberk WJ, Wakefield BJ, McManus RJ.

Am J Hypertens. 2019 Nov 15. pii: hpz182. doi: 10.1093/ajh/hpz182. [Epub ahead of print]

PMID:
31730171
8.

What next for education in evidence-based healthcare? A call for submissions.

Nunan D, Jackson R, Heneghan C.

BMJ Evid Based Med. 2019 Nov 14. pii: bmjebm-2019-111301. doi: 10.1136/bmjebm-2019-111301. [Epub ahead of print] No abstract available.

PMID:
31727639
9.

Single screening or double screening for study selection in systematic reviews?

Mahtani KR, Heneghan C, Aronson J.

BMJ Evid Based Med. 2019 Nov 13. pii: bmjebm-2019-111269. doi: 10.1136/bmjebm-2019-111269. [Epub ahead of print] No abstract available.

PMID:
31722997
10.

A randomised controlled trial of extended anticoagulation treatment versus standard treatment for the prevention of recurrent venous thromboembolism (VTE) and post-thrombotic syndrome in patients being treated for a first episode of unprovoked VTE (the ExACT study).

Bradbury C, Fletcher K, Sun Y, Heneghan C, Gardiner C, Roalfe A, Hardy P, McCahon D, Heritage G, Shackleford H, Hobbs FR, Fitzmaurice D.

Br J Haematol. 2019 Nov 12. doi: 10.1111/bjh.16275. [Epub ahead of print]

PMID:
31713863
11.

Declaring interests and restoring trust in medicine.

Heneghan C, McCartney M.

BMJ. 2019 Nov 6;367:l6236. doi: 10.1136/bmj.l6236. No abstract available.

PMID:
31694804
12.

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care.

Roddy E, Clarkson K, Blagojevic-Bucknall M, Mehta R, Oppong R, Avery A, Hay EM, Heneghan C, Hartshorne L, Hooper J, Hughes G, Jowett S, Lewis M, Little P, McCartney K, Mahtani KR, Nunan D, Santer M, Williams S, Mallen CD.

Ann Rheum Dis. 2019 Oct 30. pii: annrheumdis-2019-216154. doi: 10.1136/annrheumdis-2019-216154. [Epub ahead of print]

13.

Crisis in the supply of medicines.

Ferner RE, Aronson JK, Heneghan C.

BMJ. 2019 Oct 4;367:l5841. doi: 10.1136/bmj.l5841. No abstract available.

PMID:
31585945
14.

Is it time to end general health checks?

Heneghan C, Mahtani KR.

BMJ Evid Based Med. 2019 Sep 9. pii: bmjebm-2019-111227. doi: 10.1136/bmjebm-2019-111227. [Epub ahead of print] No abstract available.

PMID:
31501223
15.

Why reports of clinical trials should include updated meta-analyses.

Heneghan C, Aronson JK.

BMJ Evid Based Med. 2019 Aug 31. pii: bmjebm-2019-111243. doi: 10.1136/bmjebm-2019-111243. [Epub ahead of print] No abstract available.

PMID:
31473599
16.

Predictors of the effects of treatment for shoulder pain: protocol of an individual participant data meta-analysis.

van der Windt DA, Burke DL, Babatunde O, Hattle M, McRobert C, Littlewood C, Wynne-Jones G, Chesterton L, van der Heijden GJMG, Winters JC, Rhon DI, Bennell K, Roddy E, Heneghan C, Beard D, Rees JL, Riley RD.

Diagn Progn Res. 2019 Aug 8;3:15. doi: 10.1186/s41512-019-0061-x. eCollection 2019.

17.

Key concepts for making informed choices.

Aronson JK, Barends E, Boruch R, Brennan M, Chalmers I, Chislett J, Cunliffe-Jones P, Dahlgren A, Gaarder M, Haines A, Heneghan C, Matthews R, Maynard B, Oxman AD, Oxman M, Pullin A, Randall N, Roddam H, Schoonees A, Sharples J, Stewart R, Stott J, Tallis R, Thomas N, Vale L.

Nature. 2019 Aug;572(7769):303-306. doi: 10.1038/d41586-019-02407-9. No abstract available.

PMID:
31406318
18.

Biomarkers for diagnosing serious bacterial infections in older outpatients: a systematic review.

Gbinigie OA, Onakpoya IJ, Richards GC, Spencer EA, Koshiaris C, Bobrovitz N, Heneghan CJ.

BMC Geriatr. 2019 Jul 17;19(1):190. doi: 10.1186/s12877-019-1205-0.

19.

Do we need an evidence manifesto?

Dean R, Heneghan C.

Vet Rec. 2019 Jul 13;185(2):58-59. doi: 10.1136/vr.l4653.

PMID:
31296726
20.

Sleep-Wake Disturbance Related to Ocular Disease: A Systematic Review of Phase-Shifting Pharmaceutical Therapies.

Andrews CD, Foster RG, Alexander I, Vasudevan S, Downes SM, Heneghan C, Plüddemann A.

Transl Vis Sci Technol. 2019 Jun 26;8(3):49. doi: 10.1167/tvst.8.3.49. eCollection 2019 May. Review.

21.

Redefining disease definitions and preventing overdiagnosis: time to re-evaluate our priorities.

Heneghan C, Mahtani KR.

BMJ Evid Based Med. 2019 Oct;24(5):163-164. doi: 10.1136/bmjebm-2019-111219. Epub 2019 Jul 4. No abstract available.

PMID:
31273126
22.

Comparison of essential medicines lists in 137 countries.

Persaud N, Jiang M, Shaikh R, Bali A, Oronsaye E, Woods H, Drozdzal G, Rajakulasingam Y, Maraj D, Wadhawan S, Umali N, Wang R, McCall M, Aronson JK, Plüddemann A, Moja L, Magrini N, Heneghan C.

Bull World Health Organ. 2019 Jun 1;97(6):394-404C. doi: 10.2471/BLT.18.222448. Epub 2019 Apr 4.

23.

Health care: conflicted, confused, and in need of change.

McCartney M, Heneghan C, Finnikin S.

Lancet. 2019 Jun 8;393(10188):2281-2283. doi: 10.1016/S0140-6736(19)30844-X. Epub 2019 Jun 6. No abstract available.

PMID:
31180016
24.

Single or dual antiplatelet therapy after a transient ischaemic attack or minor ischaemic stroke?

Mahtani KR, Heneghan C, Aronson J.

BMJ Evid Based Med. 2019 Oct;24(5):196-197. doi: 10.1136/bmjebm-2019-111160. Epub 2019 Jun 5. Review. No abstract available.

PMID:
31167935
25.

Mixed-methods feasibility study of blood pressure self-screening for hypertension detection.

Tompson A, Fleming S, Lee MM, Monahan M, Jowett S, McCartney D, Greenfield S, Heneghan C, Ward A, Hobbs R, McManus RJ.

BMJ Open. 2019 May 29;9(5):e027986. doi: 10.1136/bmjopen-2018-027986.

26.

Routine fluoxetine in stroke.

Heneghan C, Mahtani KR.

BMJ Evid Based Med. 2019 Oct;24(5):195-196. doi: 10.1136/bmjebm-2019-111188. Epub 2019 May 29. Review. No abstract available.

PMID:
31142557
27.

Absolute effects of statins in the elderly.

Heneghan C, Mahtani KR.

BMJ Evid Based Med. 2019 Oct;24(5):200-202. doi: 10.1136/bmjebm-2019-111189. Epub 2019 May 15. Review. No abstract available.

PMID:
31092405
28.

Corrigendum to "The feasibility and acceptability of self-testing for proteinuria during pregnancy: A mixed methods approach" [Pregn. Hypertens. 12 (2018) 161-168].

Tucker KL, Bowen L, Crawford C, Mallon P, Hinton L, Lee MM, Oke J, Taylor KS, Heneghan C, Bankhead C, Mackillop L, James T, Oakeshott P, Chappell LC, McManus RJ.

Pregnancy Hypertens. 2019 Apr;16:31. doi: 10.1016/j.preghy.2019.02.005. Epub 2019 Feb 26. No abstract available.

29.

Commercial interests, transparency, and independence: a call for submissions.

Moynihan R, Macdonald H, Heneghan C, Bero L, Godlee F.

BMJ. 2019 Apr 16;365:l1706. doi: 10.1136/bmj.l1706. No abstract available.

PMID:
30992258
30.

Vitamin D does not prevent fractures and falls.

Heneghan C, Mahtani KR.

BMJ Evid Based Med. 2019 Aug;24(4):147-148. doi: 10.1136/bmjebm-2018-111129. Epub 2019 Apr 3. Review. No abstract available.

PMID:
30944101
31.

Acceptability and psychological impact of out-of-office monitoring to diagnose hypertension: an evaluation of survey data from primary care patients.

Tompson AC, Ward AM, McManus RJ, Perera R, Thompson MJ, Heneghan CJ, Nunan D.

Br J Gen Pract. 2019 Jun;69(683):e389-e397. doi: 10.3399/bjgp19X702221. Epub 2019 Mar 25.

PMID:
30910876
32.
33.

Limited evidence for diagnosing bacterial skin infections in older adults in primary care: systematic review.

Gbinigie OA, Ordóñez-Mena JM, Fanshawe T, Plüddemann A, Heneghan CJ.

BMC Geriatr. 2019 Feb 18;19(1):45. doi: 10.1186/s12877-019-1061-y.

34.

COMPare: a prospective cohort study correcting and monitoring 58 misreported trials in real time.

Goldacre B, Drysdale H, Dale A, Milosevic I, Slade E, Hartley P, Marston C, Powell-Smith A, Heneghan C, Mahtani KR.

Trials. 2019 Feb 14;20(1):118. doi: 10.1186/s13063-019-3173-2.

35.

COMPare: Qualitative analysis of researchers' responses to critical correspondence on a cohort of 58 misreported trials.

Goldacre B, Drysdale H, Marston C, Mahtani KR, Dale A, Milosevic I, Slade E, Hartley P, Heneghan C.

Trials. 2019 Feb 14;20(1):124. doi: 10.1186/s13063-019-3172-3.

36.

Oral hormone pregnancy tests and the risks of congenital malformations: a systematic review and meta-analysis.

Heneghan C, Aronson JK, Spencer E, Holman B, Mahtani KR, Perera R, Onakpoya I.

Version 2. F1000Res. 2018 Oct 31 [revised 2019 Jan 1];7:1725. doi: 10.12688/f1000research.16758.2. eCollection 2018.

37.

Introducing the EBM Verdict: research evidence relevant to clinical practice.

Heneghan C, Brassey J, Aronson J, O'Sullivan JW.

BMJ Evid Based Med. 2019 Jun;24(3):85-86. doi: 10.1136/bmjebm-2019-111172. Epub 2019 Jan 30. No abstract available.

PMID:
30700435
38.

BMJ Evidence-Based Medicine in 2018.

Heneghan C.

BMJ Evid Based Med. 2019 Apr;24(2):43-44. doi: 10.1136/bmjebm-2018-111155. Epub 2019 Jan 29. No abstract available.

PMID:
30696691
39.

Benefits and harms of pregabalin in the management of neuropathic pain: a rapid review and meta-analysis of randomised clinical trials.

Onakpoya IJ, Thomas ET, Lee JJ, Goldacre B, Heneghan CJ.

BMJ Open. 2019 Jan 21;9(1):e023600. doi: 10.1136/bmjopen-2018-023600.

40.

Practice variation in the use of tests in UK primary care: a retrospective analysis of 16 million tests performed over 3.3 million patient years in 2015/16.

O'Sullivan JW, Stevens S, Oke J, Hobbs FDR, Salisbury C, Little P, Goldacre B, Bankhead C, Aronson JK, Heneghan C, Perera R.

BMC Med. 2018 Dec 20;16(1):229. doi: 10.1186/s12916-018-1217-1.

41.

Temporal trends in use of tests in UK primary care, 2000-15: retrospective analysis of 250 million tests.

O'Sullivan JW, Stevens S, Hobbs FDR, Salisbury C, Little P, Goldacre B, Bankhead C, Aronson JK, Perera R, Heneghan C.

BMJ. 2018 Nov 28;363:k4666. doi: 10.1136/bmj.k4666. Erratum in: BMJ. 2019 Jan 29;364:l444.

42.

Reduced Salt Intake for Heart Failure: A Systematic Review.

Mahtani KR, Heneghan C, Onakpoya I, Tierney S, Aronson JK, Roberts N, Hobbs FDR, Nunan D.

JAMA Intern Med. 2018 Dec 1;178(12):1693-1700. doi: 10.1001/jamainternmed.2018.4673.

PMID:
30398532
43.

Transparency of the UK medicines regulator: auditing freedom of information requests and reasons for refusal.

Grigg SE, O'Sullivan JW, Goldacre B, Heneghan C.

BMJ Evid Based Med. 2019 Feb;24(1):20-25. doi: 10.1136/bmjebm-2018-111018. Epub 2018 Oct 30. No abstract available.

PMID:
30377149
44.

How Do Home and Clinic Blood Pressure Readings Compare in Pregnancy?

Tucker KL, Bankhead C, Hodgkinson J, Roberts N, Stevens R, Heneghan C, Rey É, Lo C, Chandiramani M, Taylor RS, North RA, Khalil A, Marko K, Waugh J, Brown M, Crawford C, Taylor KS, Mackillop L, McManus RJ.

Hypertension. 2018 Sep;72(3):686-694. doi: 10.1161/HYPERTENSIONAHA.118.10917.

45.

Patient experience of home and waiting room blood pressure measurement: a qualitative study of patients with recently diagnosed hypertension.

Tompson AC, Schwartz CL, Fleming S, Ward AM, Greenfield SM, Grant S, Hobbs FR, Heneghan CJ, McManus RJ.

Br J Gen Pract. 2018 Dec;68(677):e835-e843. doi: 10.3399/bjgp18X699761. Epub 2018 Oct 22.

46.

Sodium valproate: who knew what and when? Cumulative meta-analysis gives extra insights.

Heneghan C, Aronson JK.

BMJ Evid Based Med. 2019 Aug;24(4):127-129. doi: 10.1136/bmjebm-2018-111068. Epub 2018 Oct 22. No abstract available.

PMID:
30348656
47.

When to include clinical study reports and regulatory documents in systematic reviews.

Jefferson T, Doshi P, Boutron I, Golder S, Heneghan C, Hodkinson A, Jones M, Lefebvre C, Stewart LA.

BMJ Evid Based Med. 2018 Dec;23(6):210-217. doi: 10.1136/bmjebm-2018-110963. Epub 2018 Oct 11.

PMID:
30309870
48.

Surgical mesh and patient safety.

Heneghan C, Godlee F.

BMJ. 2018 Oct 10;363:k4231. doi: 10.1136/bmj.k4231. No abstract available.

PMID:
30305286
49.

OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE): protocol for a randomised controlled non-inferiority trial.

Sheppard JP, Burt J, Lown M, Temple E, Benson J, Ford GA, Heneghan C, Hobbs FDR, Jowett S, Little P, Mant J, Mollison J, Nickless A, Ogburn E, Payne R, Williams M, Yu LM, McManus RJ.

BMJ Open. 2018 Oct 4;8(9):e022930. doi: 10.1136/bmjopen-2018-022930.

50.

Effect of an egg ovalbumin-derived protein hydrolysate on blood pressure and cardiovascular risk in adults with a mildly elevated blood pressure: a randomized placebo-controlled crossover trial.

Lucey AJ, Heneghan C, Manning E, Kroon PA, Kiely ME.

Eur J Nutr. 2019 Oct;58(7):2823-2833. doi: 10.1007/s00394-018-1832-9. Epub 2018 Oct 3.

PMID:
30284065

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