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Items: 1 to 50 of 64

1.

Integrated genomic analyses of de novo pathways underlying atypical meningiomas.

Harmancı AS, Youngblood MW, Clark VE, Coşkun S, Henegariu O, Duran D, Erson-Omay EZ, Kaulen LD, Lee TI, Abraham BJ, Simon M, Krischek B, Timmer M, Goldbrunner R, Omay SB, Baranoski J, Baran B, Carrión-Grant G, Bai H, Mishra-Gorur K, Schramm J, Moliterno J, Vortmeyer AO, Bilgüvar K, Yasuno K, Young RA, Günel M.

Nat Commun. 2018 Apr 20;9:16215. doi: 10.1038/ncomms16215.

2.

Membrane-bound Dickkopf-1 in Foxp3+ regulatory T cells suppresses T-cell-mediated autoimmune colitis.

Chae WJ, Park JH, Henegariu O, Yilmaz S, Hao L, Bothwell ALM.

Immunology. 2017 Oct;152(2):265-275. doi: 10.1111/imm.12766. Epub 2017 Jun 27.

3.

Integrated genomic analyses of de novo pathways underlying atypical meningiomas.

Harmancı AS, Youngblood MW, Clark VE, Coşkun S, Henegariu O, Duran D, Erson-Omay EZ, Kaulen LD, Lee TI, Abraham BJ, Simon M, Krischek B, Timmer M, Goldbrunner R, Omay SB, Baranoski J, Baran B, Carrión-Grant G, Bai H, Mishra-Gorur K, Schramm J, Moliterno J, Vortmeyer AO, Bilgüvar K, Yasuno K, Young RA, Günel M.

Nat Commun. 2017 Feb 14;8:14433. doi: 10.1038/ncomms14433. Erratum in: Nat Commun. 2018 Apr 20;9:16215.

4.

Longitudinal analysis of treatment-induced genomic alterations in gliomas.

Erson-Omay EZ, Henegariu O, Omay SB, Harmancı AS, Youngblood MW, Mishra-Gorur K, Li J, Özduman K, Carrión-Grant G, Clark VE, Çağlar C, Bakırcıoğlu M, Pamir MN, Tabar V, Vortmeyer AO, Bilguvar K, Yasuno K, DeAngelis LM, Baehring JM, Moliterno J, Günel M.

Genome Med. 2017 Feb 2;9(1):12. doi: 10.1186/s13073-017-0401-9.

5.

Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas.

Clark VE, Harmancı AS, Bai H, Youngblood MW, Lee TI, Baranoski JF, Ercan-Sencicek AG, Abraham BJ, Weintraub AS, Hnisz D, Simon M, Krischek B, Erson-Omay EZ, Henegariu O, Carrión-Grant G, Mishra-Gorur K, Durán D, Goldmann JE, Schramm J, Goldbrunner R, Piepmeier JM, Vortmeyer AO, Günel JM, Bilgüvar K, Yasuno K, Young RA, Günel M.

Nat Genet. 2016 Oct;48(10):1253-9. doi: 10.1038/ng.3651. Epub 2016 Aug 22.

6.

IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation.

Oktay Y, Ülgen E, Can Ö, Akyerli CB, Yüksel Ş, Erdemgil Y, Durası IM, Henegariu OI, Nanni EP, Selevsek N, Grossmann J, Erson-Omay EZ, Bai H, Gupta M, Lee W, Turcan Ş, Özpınar A, Huse JT, Sav MA, Flanagan A, Günel M, Sezerman OU, Yakıcıer MC, Pamir MN, Özduman K.

Sci Rep. 2016 Jun 10;6:27569. doi: 10.1038/srep27569.

7.

The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation.

Chae WJ, Ehrlich AK, Chan PY, Teixeira AM, Henegariu O, Hao L, Shin JH, Park JH, Tang WH, Kim ST, Maher SE, Goldsmith-Pestana K, Shan P, Hwa J, Lee PJ, Krause DS, Rothlin CV, McMahon-Pratt D, Bothwell AL.

Immunity. 2016 Feb 16;44(2):246-58. doi: 10.1016/j.immuni.2016.01.008. Epub 2016 Feb 9.

8.

A patient with a novel homozygous missense mutation in FTO and concomitant nonsense mutation in CETP.

Çağlayan AO, Tüysüz B, Coşkun S, Quon J, Harmancı AS, Baranoski JF, Baran B, Erson-Omay EZ, Henegariu O, Mane SM, Bilgüvar K, Yasuno K, Günel M.

J Hum Genet. 2016 May;61(5):395-403. doi: 10.1038/jhg.2015.160. Epub 2016 Jan 7.

9.

Integrated genomic characterization of IDH1-mutant glioma malignant progression.

Bai H, Harmancı AS, Erson-Omay EZ, Li J, Coşkun S, Simon M, Krischek B, Özduman K, Omay SB, Sorensen EA, Turcan Ş, Bakırcığlu M, Carrión-Grant G, Murray PB, Clark VE, Ercan-Sencicek AG, Knight J, Sencar L, Altınok S, Kaulen LD, Gülez B, Timmer M, Schramm J, Mishra-Gorur K, Henegariu O, Moliterno J, Louvi A, Chan TA, Tannheimer SL, Pamir MN, Vortmeyer AO, Bilguvar K, Yasuno K, Günel M.

Nat Genet. 2016 Jan;48(1):59-66. doi: 10.1038/ng.3457. Epub 2015 Nov 30.

10.

Mutations in KATNB1 Cause Complex Cerebral Malformations by Disrupting Asymmetrically Dividing Neural Progenitors.

Mishra-Gorur K, Çağlayan AO, Schaffer AE, Chabu C, Henegariu O, Vonhoff F, Akgümüş GT, Nishimura S, Han W, Tu S, Baran B, Gümüş H, Dilber C, Zaki MS, Hossni HAA, Rivière JB, Kayserili H, Spencer EG, Rosti RÖ, Schroth J, Per H, Çağlar C, Çağlar Ç, Dölen D, Baranoski JF, Kumandaş S, Minja FJ, Erson-Omay EZ, Mane SM, Lifton RP, Xu T, Keshishian H, Dobyns WB, Chi NC, Šestan N, Louvi A, Bilgüvar K, Yasuno K, Gleeson JG, Günel M.

Neuron. 2015 Jan 7;85(1):228. doi: 10.1016/j.neuron.2014.12.046. Epub 2015 Jan 7. No abstract available.

11.

Mutations in KATNB1 cause complex cerebral malformations by disrupting asymmetrically dividing neural progenitors.

Mishra-Gorur K, Çağlayan AO, Schaffer AE, Chabu C, Henegariu O, Vonhoff F, Akgümüş GT, Nishimura S, Han W, Tu S, Baran B, Gümüş H, Dilber C, Zaki MS, Hossni HA, Rivière JB, Kayserili H, Spencer EG, Rosti RÖ, Schroth J, Per H, Çağlar C, Çağlar Ç, Dölen D, Baranoski JF, Kumandaş S, Minja FJ, Erson-Omay EZ, Mane SM, Lifton RP, Xu T, Keshishian H, Dobyns WB, Chi NC, Šestan N, Louvi A, Bilgüvar K, Yasuno K, Gleeson JG, Günel M.

Neuron. 2014 Dec 17;84(6):1226-39. doi: 10.1016/j.neuron.2014.12.014. Erratum in: Neuron. 2015 Jan 7;85(1):228. Neuron. 2015 Jan 7;85(1):228.

12.

The receptor for advanced glycation end products (RAGE) affects T cell differentiation in OVA induced asthma.

Akirav EM, Henegariu O, Preston-Hurlburt P, Schmidt AM, Clynes R, Herold KC.

PLoS One. 2014 Apr 23;9(4):e95678. doi: 10.1371/journal.pone.0095678. eCollection 2014.

13.

Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO.

Clark VE, Erson-Omay EZ, Serin A, Yin J, Cotney J, Ozduman K, Avşar T, Li J, Murray PB, Henegariu O, Yilmaz S, Günel JM, Carrión-Grant G, Yilmaz B, Grady C, Tanrikulu B, Bakircioğlu M, Kaymakçalan H, Caglayan AO, Sencar L, Ceyhun E, Atik AF, Bayri Y, Bai H, Kolb LE, Hebert RM, Omay SB, Mishra-Gorur K, Choi M, Overton JD, Holland EC, Mane S, State MW, Bilgüvar K, Baehring JM, Gutin PH, Piepmeier JM, Vortmeyer A, Brennan CW, Pamir MN, Kiliç T, Lifton RP, Noonan JP, Yasuno K, Günel M.

Science. 2013 Mar 1;339(6123):1077-80. doi: 10.1126/science.1233009. Epub 2013 Jan 24.

14.

Anti-serpin antibody-mediated regulation of proteases in autoimmune diabetes.

Baldzizhar R, Fedorchuk C, Jha M, Rathinam C, Henegariu O, Czyzyk J.

J Biol Chem. 2013 Jan 18;288(3):1612-9. doi: 10.1074/jbc.M112.409664. Epub 2012 Nov 29. Erratum in: J Biol Chem. 2013 Apr 19;288(16):11506.

15.

Analysis of human biologics with a mouse skin transplant model in humanized mice.

Waldron-Lynch F, Deng S, Preston-Hurlburt P, Henegariu O, Herold KC.

Am J Transplant. 2012 Oct;12(10):2652-62. doi: 10.1111/j.1600-6143.2012.04178.x. Epub 2012 Aug 17.

16.

Enhanced anti-serpin antibody activity inhibits autoimmune inflammation in type 1 diabetes.

Czyzyk J, Henegariu O, Preston-Hurlburt P, Baldzizhar R, Fedorchuk C, Esplugues E, Bottomly K, Gorus FK, Herold K, Flavell RA.

J Immunol. 2012 Jun 15;188(12):6319-27. doi: 10.4049/jimmunol.1200467. Epub 2012 May 16.

17.

RAGE expression in human T cells: a link between environmental factors and adaptive immune responses.

Akirav EM, Preston-Hurlburt P, Garyu J, Henegariu O, Clynes R, Schmidt AM, Herold KC.

PLoS One. 2012;7(4):e34698. doi: 10.1371/journal.pone.0034698. Epub 2012 Apr 11.

18.

Teplizumab induces human gut-tropic regulatory cells in humanized mice and patients.

Waldron-Lynch F, Henegariu O, Deng S, Preston-Hurlburt P, Tooley J, Flavell R, Herold KC.

Sci Transl Med. 2012 Jan 25;4(118):118ra12. doi: 10.1126/scitranslmed.3003401.

19.

Detection of β cell death in diabetes using differentially methylated circulating DNA.

Akirav EM, Lebastchi J, Galvan EM, Henegariu O, Akirav M, Ablamunits V, Lizardi PM, Herold KC.

Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19018-23. doi: 10.1073/pnas.1111008108. Epub 2011 Nov 9.

20.

Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation.

Ablamunits V, Henegariu O, Hansen JB, Opare-Addo L, Preston-Hurlburt P, Santamaria P, Mandrup-Poulsen T, Herold KC.

Diabetes. 2012 Jan;61(1):145-54. doi: 10.2337/db11-1033. Epub 2011 Oct 31.

21.

NKG2A is a marker for acquisition of regulatory function by human CD8+ T cells activated with anti-CD3 antibody.

Ablamunits V, Henegariu O, Preston-Hurlburt P, Herold KC.

Eur J Immunol. 2011 Jul;41(7):1832-42. doi: 10.1002/eji.201041258. Epub 2011 Jun 6.

22.

Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis.

Chae WJ, Gibson TF, Zelterman D, Hao L, Henegariu O, Bothwell AL.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5540-4. doi: 10.1073/pnas.0912675107. Epub 2010 Mar 8.

23.

Elevated expression of MCP-1, IL-2 and PTPR-N in basal ganglia of Tourette syndrome cases.

Morer A, Chae W, Henegariu O, Bothwell AL, Leckman JF, Kawikova I.

Brain Behav Immun. 2010 Oct;24(7):1069-73. doi: 10.1016/j.bbi.2010.02.007. Epub 2010 Mar 1.

PMID:
20193755
24.

Inflammatory regulation by TLR3 in acute hepatitis.

Xiao X, Zhao P, Rodriguez-Pinto D, Qi D, Henegariu O, Alexopoulou L, Flavell RA, Wong FS, Wen L.

J Immunol. 2009 Sep 15;183(6):3712-9. doi: 10.4049/jimmunol.0901221. Epub 2009 Aug 26.

25.

RAGE ligation affects T cell activation and controls T cell differentiation.

Chen Y, Akirav EM, Chen W, Henegariu O, Moser B, Desai D, Shen JM, Webster JC, Andrews RC, Mjalli AM, Rothlein R, Schmidt AM, Clynes R, Herold KC.

J Immunol. 2008 Sep 15;181(6):4272-8.

26.

Treatment with CD20-specific antibody prevents and reverses autoimmune diabetes in mice.

Hu CY, Rodriguez-Pinto D, Du W, Ahuja A, Henegariu O, Wong FS, Shlomchik MJ, Wen L.

J Clin Invest. 2007 Dec;117(12):3857-67.

27.

Characterization of a severe parenchymal phenotype of experimental autoimmune encephalomyelitis in (C57BL6xB10.PL)F1 mice.

Carrithers MD, Carrithers LM, Czyzyk J, Henegariu O.

J Neuroimmunol. 2007 Jul;187(1-2):31-43. Epub 2007 May 18.

28.

The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells.

Chae WJ, Henegariu O, Lee SK, Bothwell AL.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9631-6. Epub 2006 Jun 12.

29.

JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance.

Gao Y, Tao J, Li MO, Zhang D, Chi H, Henegariu O, Kaech SM, Davis RJ, Flavell RA, Yin Z.

J Immunol. 2005 Nov 1;175(9):5783-9.

30.

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract.

Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nuñez G, Flavell RA.

Science. 2005 Feb 4;307(5710):731-4.

31.

SGK1, a potential regulator of c-fms related breast cancer aggressiveness.

Tangir J, Bonafé N, Gilmore-Hebert M, Henegariu O, Chambers SK.

Clin Exp Metastasis. 2004;21(6):477-83.

PMID:
15679045
32.

DNA polymerase beta interacts with TRF2 and induces telomere dysfunction in a murine mammary cell line.

Fotiadou P, Henegariu O, Sweasy JB.

Cancer Res. 2004 Jun 1;64(11):3830-7.

33.

Characterization of gains, losses, and regional amplification in testicular germ cell tumor cell lines by comparative genomic hybridization.

Henegariu O, Heerema NA, Thurston V, Jung SH, Pera M, Vance GH.

Cancer Genet Cytogenet. 2004 Jan 1;148(1):14-20.

PMID:
14697636
34.

Activation of CD4 T cells by Raf-independent effectors of Ras.

Czyzyk J, Brogdon JL, Badou A, Henegariu O, Preston Hurlburt P, Flavell R, Bottomly K.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):6003-8. Epub 2003 Apr 29.

35.

Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype.

State MW, Greally JM, Cuker A, Bowers PN, Henegariu O, Morgan TM, Gunel M, DiLuna M, King RA, Nelson C, Donovan A, Anderson GM, Leckman JF, Hawkins T, Pauls DL, Lifton RP, Ward DC.

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4684-9. Epub 2003 Apr 7.

36.

Marrow-derived cells as vehicles for delivery of gene therapy to pulmonary epithelium.

Grove JE, Lutzko C, Priller J, Henegariu O, Theise ND, Kohn DB, Krause DS.

Am J Respir Cell Mol Biol. 2002 Dec;27(6):645-51.

PMID:
12444022
37.

Radiation pneumonitis in mice: a severe injury model for pneumocyte engraftment from bone marrow.

Theise ND, Henegariu O, Grove J, Jagirdar J, Kao PN, Crawford JM, Badve S, Saxena R, Krause DS.

Exp Hematol. 2002 Nov;30(11):1333-8.

PMID:
12423687
38.

Rapid DNA fiber technique for size measurements of linear and circular DNA probes.

Henegariu O, Grober L, Haskins W, Bowers PN, State MW, Ohmido N, Bray-Ward P, Ward DC.

Biotechniques. 2001 Aug;31(2):246-50. No abstract available.

39.

Alteration in expression of the rat mitochondrial ATPase 6 gene during Pneumocystis carinii infection.

Asnicar MA, Henegariu O, Shaw MM, Goheen MP, Bartlett MS, Smith JW, Lee CH.

BMC Microbiol. 2001;1:8. Epub 2001 Jun 29.

40.

A triple color FISH technique for mouse chromosome identification.

Henegariu O, Dunai J, Chen XN, Korenberg JR, Ward DC, Greally JM.

Mamm Genome. 2001 Jun;12(6):462-5. No abstract available.

PMID:
11353394
41.

Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell.

Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R, Neutzel S, Sharkis SJ.

Cell. 2001 May 4;105(3):369-77.

42.

Cryptic translocation identification in human and mouse using several telomeric multiplex fish (TM-FISH) strategies.

Henegariu O, Artan S, Greally JM, Chen XN, Korenberg JR, Vance GH, Stubbs L, Bray-Ward P, Ward DC.

Lab Invest. 2001 Apr;81(4):483-91.

PMID:
11304567
43.

Small marker chromosome identification in metaphase and interphase using centromeric multiplex fish (CM-FISH).

Henegariu O, Bray-Ward P, Artan S, Vance GH, Qumsyieh M, Ward DC.

Lab Invest. 2001 Apr;81(4):475-81.

PMID:
11304566
44.

Improvements in cytogenetic slide preparation: controlled chromosome spreading, chemical aging and gradual denaturing.

Henegariu O, Heerema NA, Lowe Wright L, Bray-Ward P, Ward DC, Vance GH.

Cytometry. 2001 Feb 1;43(2):101-9.

PMID:
11169574
45.

Liver from bone marrow in humans.

Theise ND, Nimmakayalu M, Gardner R, Illei PB, Morgan G, Teperman L, Henegariu O, Krause DS.

Hepatology. 2000 Jul;32(1):11-6.

PMID:
10869283
46.

Chromosome instability contributes to loss of heterozygosity in mice lacking p53.

Shao C, Deng L, Henegariu O, Liang L, Stambrook PJ, Tischfield JA.

Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7405-10.

47.

Simple method for preparation of fluor/hapten-labeled dUTP.

Nimmakayalu M, Henegariu O, Ward DC, Bray-Ward P.

Biotechniques. 2000 Mar;28(3):518-22.

48.

Custom fluorescent-nucleotide synthesis as an alternative method for nucleic acid labeling.

Henegariu O, Bray-Ward P, Ward DC.

Nat Biotechnol. 2000 Mar;18(3):345-8.

PMID:
10700155
49.

Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation.

Theise ND, Badve S, Saxena R, Henegariu O, Sell S, Crawford JM, Krause DS.

Hepatology. 2000 Jan;31(1):235-40.

PMID:
10613752
50.

Colour-changing karyotyping: an alternative to M-FISH/SKY.

Henegariu O, Heerema NA, Bray-Ward P, Ward DC.

Nat Genet. 1999 Nov;23(3):263-4. No abstract available.

PMID:
10545937

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