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Items: 21

1.

A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir.

de Weger VA, Stuurman FE, Koolen SLW, Moes JJ, Hendrikx JJMA, Sawicki E, Thijssen B, Keessen M, Rosing H, Mergui-Roelvink M, Huitema ADR, Nuijen B, Beijnen JH, Schellens JHM, Marchetti S.

Clin Cancer Res. 2019 Sep 15;25(18):5466-5474. doi: 10.1158/1078-0432.CCR-17-2299. Epub 2019 Jun 19.

PMID:
31217201
2.

A dose-escalation study of bi-daily once weekly oral docetaxel either as ModraDoc001 or ModraDoc006 combined with ritonavir.

de Weger VA, Stuurman FE, Hendrikx JJMA, Moes JJ, Sawicki E, Huitema ADR, Nuijen B, Thijssen B, Rosing H, Keessen M, Mergui-Roelvink M, Beijnen JH, Schellens JHM, Marchetti S.

Eur J Cancer. 2017 Nov;86:217-225. doi: 10.1016/j.ejca.2017.09.010. Epub 2017 Oct 12.

PMID:
29031170
3.

Fixed Dosing of Monoclonal Antibodies in Oncology.

Hendrikx JJMA, Haanen JBAG, Voest EE, Schellens JHM, Huitema ADR, Beijnen JH.

Oncologist. 2017 Oct;22(10):1212-1221. doi: 10.1634/theoncologist.2017-0167. Epub 2017 Jul 28. Review.

4.

Crizotinib-induced fatal fulminant liver failure.

van Geel RM, Hendrikx JJ, Vahl JE, van Leerdam ME, van den Broek D, Huitema AD, Beijnen JH, Schellens JH, Burgers SA.

Lung Cancer. 2016 Mar;93:17-9. doi: 10.1016/j.lungcan.2015.12.010. Epub 2015 Dec 30.

PMID:
26898609
5.

Development of a Tumour Growth Inhibition Model to Elucidate the Effects of Ritonavir on Intratumoural Metabolism and Anti-tumour Effect of Docetaxel in a Mouse Model for Hereditary Breast Cancer.

Yu H, Hendrikx JJ, Rottenberg S, Schellens JH, Beijnen JH, Huitema AD.

AAPS J. 2016 Mar;18(2):362-71. doi: 10.1208/s12248-015-9838-1. Epub 2015 Nov 24.

6.

P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice.

Tang SC, Kort A, Cheung KL, Rosing H, Fukami T, Durmus S, Wagenaar E, Hendrikx JJ, Nakajima M, van Vlijmen BJ, Beijnen JH, Schinkel AH.

Mol Pharm. 2015 Oct 5;12(10):3714-23. doi: 10.1021/acs.molpharmaceut.5b00470. Epub 2015 Sep 15.

PMID:
26317243
7.

Ritonavir inhibits intratumoral docetaxel metabolism and enhances docetaxel antitumor activity in an immunocompetent mouse breast cancer model.

Hendrikx JJ, Lagas JS, Song JY, Rosing H, Schellens JH, Beijnen JH, Rottenberg S, Schinkel AH.

Int J Cancer. 2016 Feb 1;138(3):758-69. doi: 10.1002/ijc.29812. Epub 2015 Sep 21.

8.

Apical ABC transporters and cancer chemotherapeutic drug disposition.

Durmus S, Hendrikx JJ, Schinkel AH.

Adv Cancer Res. 2015;125:1-41. doi: 10.1016/bs.acr.2014.10.001. Epub 2015 Jan 8. Review.

PMID:
25640265
9.

P-gp and taxanes.

Hendrikx JJ, Beijnen JH, Schinkel AH.

Oncoscience. 2014 Jun 19;1(7):478-9. eCollection 2014. No abstract available.

10.

Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.

Iusuf D, Hendrikx JJ, van Esch A, van de Steeg E, Wagenaar E, Rosing H, Beijnen JH, Schinkel AH.

Int J Cancer. 2015 Jan 1;136(1):225-33. doi: 10.1002/ijc.28970. Epub 2014 Jun 3.

11.

Quantification of taxanes in biological matrices: a review of bioanalytical assays and recommendations for development of new assays.

Hendrikx JJ, Rosing H, Schinkel AH, Schellens JH, Beijnen JH.

Bioanalysis. 2014 Apr;6(7):993-1010. doi: 10.4155/bio.14.48. Review.

PMID:
24806907
12.

Oral co-administration of elacridar and ritonavir enhances plasma levels of oral paclitaxel and docetaxel without affecting relative brain accumulation.

Hendrikx JJ, Lagas JS, Wagenaar E, Rosing H, Schellens JH, Beijnen JH, Schinkel AH.

Br J Cancer. 2014 May 27;110(11):2669-76. doi: 10.1038/bjc.2014.222. Epub 2014 Apr 29.

13.

Severe lactic acidosis in a diabetic patient after ethanol abuse and floor cleaner intake.

Hendrikx JJ, Lagas JS, Daling R, Hooijberg JH, Schellens JH, Beijnen JH, Brandjes DP, Huitema AD.

Basic Clin Pharmacol Toxicol. 2014 Nov;115(5):472-5. doi: 10.1111/bcpt.12251. Epub 2014 Apr 28.

14.

The effect of complementary and alternative medicines on CYP3A4-mediated metabolism of three different substrates: 7-benzyloxy-4-trifluoromethyl-coumarin, midazolam and docetaxel.

Mooiman KD, Maas-Bakker RF, Hendrikx JJ, Bank PC, Rosing H, Beijnen JH, Schellens JH, Meijerman I.

J Pharm Pharmacol. 2014 Jun;66(6):865-74. doi: 10.1111/jphp.12208. Epub 2014 Jan 7.

PMID:
24392691
15.

Genetically modified mouse models for oral drug absorption and disposition.

Tang SC, Hendrikx JJ, Beijnen JH, Schinkel AH.

Curr Opin Pharmacol. 2013 Dec;13(6):853-8. doi: 10.1016/j.coph.2013.08.011. Epub 2013 Sep 8. Review.

PMID:
24021267
16.

Combined quantification of paclitaxel, docetaxel and ritonavir in human feces and urine using LC-MS/MS.

Hendrikx JJ, Rosing H, Schinkel AH, Schellens JH, Beijnen JH.

Biomed Chromatogr. 2014 Feb;28(2):302-10. doi: 10.1002/bmc.3021. Epub 2013 Aug 29.

PMID:
23996474
17.

Quantification of docetaxel and its metabolites in human plasma by liquid chromatography/tandem mass spectrometry.

Hendrikx JJ, Dubbelman AC, Rosing H, Schinkel AH, Schellens JH, Beijnen JH.

Rapid Commun Mass Spectrom. 2013 Sep 15;27(17):1925-34. doi: 10.1002/rcm.6654.

PMID:
23939959
18.

Pharmacokinetic evaluation of three oral formulations of docetaxel boosted with ritonavir: two single-drug formulations vs. a fixed-dose combination tablet.

Moes JJ, Stuurman FE, Hendrikx JJ, Marchetti S, Huitema AD, Beijnen JH, Schellens JH, Nuijen B.

Drug Deliv Transl Res. 2013 Jun;3(3):243-51. doi: 10.1007/s13346-012-0127-6.

PMID:
25788133
19.

P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.

Hendrikx JJ, Lagas JS, Rosing H, Schellens JH, Beijnen JH, Schinkel AH.

Int J Cancer. 2013 May 15;132(10):2439-47. doi: 10.1002/ijc.27912. Epub 2012 Nov 14.

20.

A sensitive combined assay for the quantification of paclitaxel, docetaxel and ritonavir in human plasma using liquid chromatography coupled with tandem mass spectrometry.

Hendrikx JJ, Hillebrand MJ, Thijssen B, Rosing H, Schinkel AH, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Oct 15;879(28):2984-90. doi: 10.1016/j.jchromb.2011.08.034. Epub 2011 Aug 31.

PMID:
21920826
21.

Methylnaltrexone.

Hendrikx JJ, Beijnen JH, Schellens JH.

Oncologist. 2009 Jul;14(7):679-82. doi: 10.1634/theoncologist.2009-0049. Epub 2009 Jul 15. Review. No abstract available.

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