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Items: 1 to 50 of 209

1.

Evidence for enhanced Bruton's tyrosine kinase activity in transitional and naïve B cells of patients with granulomatosis with polyangiitis.

von Borstel A, Abdulahad WH, Sanders JS, Rip J, Neys SFH, Hendriks RW, Stegeman CA, Heeringa P, Rutgers A, Corneth OBJ.

Rheumatology (Oxford). 2019 Jun 17. pii: kez205. doi: 10.1093/rheumatology/kez205. [Epub ahead of print]

PMID:
31209475
2.

KLRG1 and NKp46 discriminate subpopulations of human CD117+CRTH2- ILCs biased toward ILC2 or ILC3.

Nagasawa M, Heesters BA, Kradolfer CMA, Krabbendam L, Martinez-Gonzalez I, de Bruijn MJW, Golebski K, Hendriks RW, Stadhouders R, Spits H, Bal SM.

J Exp Med. 2019 Jun 14. pii: jem.20190490. doi: 10.1084/jem.20190490. [Epub ahead of print]

PMID:
31201208
3.

DNGR1-mediated deletion of A20/Tnfaip3 in dendritic cells alters T and B-cell homeostasis and promotes autoimmune liver pathology.

Das T, Bergen IM, Koudstaal T, van Hulst JAC, van Loo G, Boonstra A, Vanwolleghem T, Leung PSC, Gershwin ME, Hendriks RW, Kool M.

J Autoimmun. 2019 May 28. pii: S0896-8411(19)30002-2. doi: 10.1016/j.jaut.2019.05.007. [Epub ahead of print]

PMID:
31151831
4.

Responsiveness of Chronic Lymphocytic Leukemia cells to B cell receptor stimulation is associated with low expression of regulatory molecules of the Nuclear Factor-κB pathway.

Meijers RWJ, Muggen AF, Leon LG, de Bie M, van Dongen JJM, Hendriks RW, Langerak AW.

Haematologica. 2019 May 16. pii: haematol.2018.215566. doi: 10.3324/haematol.2018.215566. [Epub ahead of print]

5.

Characterization of donor and recipient CD8+ tissue-resident memory T cells in transplant nephrectomies.

de Leur K, Dieterich M, Hesselink DA, Corneth OBJ, Dor FJMF, de Graav GN, Peeters AMA, Mulder A, Kimenai HJAN, Claas FHJ, Clahsen-van Groningen MC, van der Laan LJW, Hendriks RW, Baan CC.

Sci Rep. 2019 Apr 12;9(1):5984. doi: 10.1038/s41598-019-42401-9.

6.

Correction to: Role of Bruton's tyrosine kinase in B cells and malignancies.

Pal Singh S, Dammeijer F, Hendriks RW.

Mol Cancer. 2019 Apr 3;18(1):79. doi: 10.1186/s12943-019-1009-z.

7.

Platelet Btk is Required for Maintaining Lung Vascular Integrity during Murine Pneumococcal Pneumosepsis.

de Porto APNA, Claushuis TAM, van der Donk LEH, de Beer R, de Boer OJ, Florquin S, Roelofs JJTH, Hendriks RW, van der Poll T, Van't Veer C, de Vos AF.

Thromb Haemost. 2019 Jun;119(6):930-940. doi: 10.1055/s-0039-1681046. Epub 2019 Mar 14.

PMID:
30873567
8.

Lack of IL-17 Receptor A signaling aggravates lymphoproliferation in C57BL/6 lpr mice.

Corneth OBJ, Schaper F, Luk F, Asmawidjaja PS, Mus AMC, Horst G, Heeringa P, Hendriks RW, Westra J, Lubberts E.

Sci Rep. 2019 Mar 11;9(1):4032. doi: 10.1038/s41598-019-39483-w.

9.

Toll-Like Receptor Signaling Drives Btk-Mediated Autoimmune Disease.

Rip J, de Bruijn MJW, Appelman MK, Pal Singh S, Hendriks RW, Corneth OBJ.

Front Immunol. 2019 Jan 30;10:95. doi: 10.3389/fimmu.2019.00095. eCollection 2019.

10.

Group 2 Innate Lymphoid Cells in Human Respiratory Disorders.

van der Ploeg EK, Carreras Mascaro A, Huylebroeck D, Hendriks RW, Stadhouders R.

J Innate Immun. 2019 Feb 6:1-16. doi: 10.1159/000496212. [Epub ahead of print] Review.

11.

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia.

de Porto AP, Liu Z, de Beer R, Florquin S, de Boer OJ, Hendriks RW, van der Poll T, de Vos AF.

Mol Med. 2019 Jan 15;25(1):3. doi: 10.1186/s10020-018-0069-7.

12.

Induction of Peripheral Effector CD8 T-cell Proliferation by Combination of Paclitaxel, Carboplatin, and Bevacizumab in Non-small Cell Lung Cancer Patients.

de Goeje PL, Poncin M, Bezemer K, Kaijen-Lambers MEH, Groen HJM, Smit EF, Dingemans AC, Kunert A, Hendriks RW, Aerts JGJV.

Clin Cancer Res. 2019 Apr 1;25(7):2219-2227. doi: 10.1158/1078-0432.CCR-18-2243. Epub 2019 Jan 14.

PMID:
30642911
13.

Low-dose cyclophosphamide depletes circulating naïve and activated regulatory T cells in malignant pleural mesothelioma patients synergistically treated with dendritic cell-based immunotherapy.

Noordam L, Kaijen MEH, Bezemer K, Cornelissen R, Maat LAPWM, Hoogsteden HC, Aerts JGJV, Hendriks RW, Hegmans JPJJ, Vroman H.

Oncoimmunology. 2018 Jul 30;7(12):e1474318. doi: 10.1080/2162402X.2018.1474318. eCollection 2018.

14.

Antibodies to Protein but Not Glycolipid Structures Are Important for Host Defense against Mycoplasma pneumoniae.

Meyer Sauteur PM, de Bruijn ACJM, Graça C, Tio-Gillen AP, Estevão SC, Hoogenboezem T, Hendriks RW, Berger C, Jacobs BC, van Rossum AMC, Huizinga R, Unger WWJ.

Infect Immun. 2019 Jan 24;87(2). pii: e00663-18. doi: 10.1128/IAI.00663-18. Print 2019 Feb.

PMID:
30396892
15.

Increased surface expression of NOTCH on memory T cells in peripheral blood from patients with asthma.

Tindemans I, Vroman H, Lukkes M, van Nimwegen M, de Bruijn MJW, Li BWS, Kleinjan A, de Boer GM, Tramper-Stranders GA, Kool M, Braunstahl GJ, Hendriks RW.

J Allergy Clin Immunol. 2019 Feb;143(2):769-771.e3. doi: 10.1016/j.jaci.2018.09.012. Epub 2018 Oct 5. No abstract available.

PMID:
30296524
16.

Identification of Distinct Unmutated Chronic Lymphocytic Leukemia Subsets in Mice Based on Their T Cell Dependency.

Pal Singh S, de Bruijn MJW, de Almeida MP, Meijers RWJ, Nitschke L, Langerak AW, Pillai SY, Stadhouders R, Hendriks RW.

Front Immunol. 2018 Sep 13;9:1996. doi: 10.3389/fimmu.2018.01996. eCollection 2018.

17.

Autologous Dendritic Cell Therapy in Mesothelioma Patients Enhances Frequencies of Peripheral CD4 T Cells Expressing HLA-DR, PD-1, or ICOS.

de Goeje PL, Klaver Y, Kaijen-Lambers MEH, Langerak AW, Vroman H, Kunert A, Lamers CHJ, Aerts JGJV, Debets R, Hendriks RW.

Front Immunol. 2018 Sep 7;9:2034. doi: 10.3389/fimmu.2018.02034. eCollection 2018.

18.

Distinct Roles for Bruton's Tyrosine Kinase in B Cell Immune Synapse Formation.

Roman-Garcia S, Merino-Cortes SV, Gardeta SR, de Bruijn MJW, Hendriks RW, Carrasco YR.

Front Immunol. 2018 Sep 6;9:2027. doi: 10.3389/fimmu.2018.02027. eCollection 2018.

19.

House dust mite-driven neutrophilic airway inflammation in mice with TNFAIP3-deficient myeloid cells is IL-17-independent.

Vroman H, Das T, Bergen IM, van Hulst JAC, Ahmadi F, van Loo G, Lubberts E, Hendriks RW, Kool M.

Clin Exp Allergy. 2018 Dec;48(12):1705-1714. doi: 10.1111/cea.13262. Epub 2018 Sep 27.

PMID:
30171721
20.

Frequencies of circulating regulatory TIGIT+CD38+ effector T cells correlate with the course of inflammatory bowel disease.

Joosse ME, Menckeberg CL, de Ruiter LF, Raatgeep HRC, van Berkel LA, Simons-Oosterhuis Y, Tindemans I, Muskens AFM, Hendriks RW, Hoogenboezem RM, Cupedo T, de Ridder L, Escher JC, Veenbergen S, Samsom JN.

Mucosal Immunol. 2019 Jan;12(1):154-163. doi: 10.1038/s41385-018-0078-4. Epub 2018 Aug 20.

PMID:
30127383
21.

Effect of Dietary Fiber and Metabolites on Mast Cell Activation and Mast Cell-Associated Diseases.

Folkerts J, Stadhouders R, Redegeld FA, Tam SY, Hendriks RW, Galli SJ, Maurer M.

Front Immunol. 2018 May 29;9:1067. doi: 10.3389/fimmu.2018.01067. eCollection 2018. Review.

22.

T cells and ILC2s are major effector cells in influenza-induced exacerbation of allergic airway inflammation in mice.

Li BWS, de Bruijn MJW, Lukkes M, van Nimwegen M, Bergen IM, KleinJan A, GeurtsvanKessel CH, Andeweg A, Rimmelzwaan GF, Hendriks RW.

Eur J Immunol. 2019 Jan;49(1):144-156. doi: 10.1002/eji.201747421. Epub 2018 Jun 11.

23.

Fibrocytes are increased in lung and peripheral blood of patients with idiopathic pulmonary fibrosis.

Heukels P, van Hulst JAC, van Nimwegen M, Boorsma CE, Melgert BN, van den Toorn LM, Boomars KAT, Wijsenbeek MS, Hoogsteden H, von der Thüsen JH, Hendriks RW, Kool M, van den Blink B.

Respir Res. 2018 May 10;19(1):90. doi: 10.1186/s12931-018-0798-8.

24.

The Role of Bruton's Tyrosine Kinase in Immune Cell Signaling and Systemic Autoimmunity.

Rip J, Van Der Ploeg EK, Hendriks RW, Corneth OBJ.

Crit Rev Immunol. 2018;38(1):17-62. doi: 10.1615/CritRevImmunol.2018025184.

PMID:
29717662
25.

A20/Tumor Necrosis Factor α-Induced Protein 3 in Immune Cells Controls Development of Autoinflammation and Autoimmunity: Lessons from Mouse Models.

Das T, Chen Z, Hendriks RW, Kool M.

Front Immunol. 2018 Feb 21;9:104. doi: 10.3389/fimmu.2018.00104. eCollection 2018. Review.

26.

Epigenome analysis links gene regulatory elements in group 2 innate lymphocytes to asthma susceptibility.

Stadhouders R, Li BWS, de Bruijn MJW, Gomez A, Rao TN, Fehling HJ, van IJcken WFJ, Lim AI, Di Santo JP, Graf T, Hendriks RW.

J Allergy Clin Immunol. 2018 Dec;142(6):1793-1807. doi: 10.1016/j.jaci.2017.12.1006. Epub 2018 Mar 2.

PMID:
29486229
27.

Role of Bruton's tyrosine kinase in B cells and malignancies.

Pal Singh S, Dammeijer F, Hendriks RW.

Mol Cancer. 2018 Feb 19;17(1):57. doi: 10.1186/s12943-018-0779-z. Review. Erratum in: Mol Cancer. 2019 Apr 3;18(1):79.

28.

Increased T-helper 17.1 cells in sarcoidosis mediastinal lymph nodes.

Broos CE, Koth LL, van Nimwegen M, In 't Veen JCCM, Paulissen SMJ, van Hamburg JP, Annema JT, Heller-Baan R, Kleinjan A, Hoogsteden HC, Wijsenbeek MS, Hendriks RW, van den Blink B, Kool M.

Eur Respir J. 2018 Mar 1;51(3). pii: 1701124. doi: 10.1183/13993003.01124-2017. Print 2018 Mar.

PMID:
29449421
29.

A pathophysiological role of PDE3 in allergic airway inflammation.

Beute J, Lukkes M, Koekoek EP, Nastiti H, Ganesh K, de Bruijn MJ, Hockman S, van Nimwegen M, Braunstahl GJ, Boon L, Lambrecht BN, Manganiello VC, Hendriks RW, KleinJan A.

JCI Insight. 2018 Jan 25;3(2). pii: 94888. doi: 10.1172/jci.insight.94888. eCollection 2018 Jan 25.

30.

A cellular and molecular view of T helper 17 cell plasticity in autoimmunity.

Stadhouders R, Lubberts E, Hendriks RW.

J Autoimmun. 2018 Feb;87:1-15. doi: 10.1016/j.jaut.2017.12.007. Epub 2017 Dec 22. Review.

31.

Group 2 Innate Lymphoid Cells Exhibit a Dynamic Phenotype in Allergic Airway Inflammation.

Li BWS, Stadhouders R, de Bruijn MJW, Lukkes M, Beerens DMJM, Brem MD, KleinJan A, Bergen I, Vroman H, Kool M, van IJcken WFJ, Rao TN, Fehling HJ, Hendriks RW.

Front Immunol. 2017 Dec 1;8:1684. doi: 10.3389/fimmu.2017.01684. eCollection 2017.

32.

Autologous Dendritic Cells Pulsed with Allogeneic Tumor Cell Lysate in Mesothelioma: From Mouse to Human.

Aerts JGJV, de Goeje PL, Cornelissen R, Kaijen-Lambers MEH, Bezemer K, van der Leest CH, Mahaweni NM, Kunert A, Eskens FALM, Waasdorp C, Braakman E, van der Holt B, Vulto AG, Hendriks RW, Hegmans JPJJ, Hoogsteden HC.

Clin Cancer Res. 2018 Feb 15;24(4):766-776. doi: 10.1158/1078-0432.CCR-17-2522. Epub 2017 Dec 12.

33.

T Follicular Helper Cells As a New Target for Immunosuppressive Therapies.

Yan L, de Leur K, Hendriks RW, van der Laan LJW, Shi Y, Wang L, Baan CC.

Front Immunol. 2017 Nov 7;8:1510. doi: 10.3389/fimmu.2017.01510. eCollection 2017. Review.

34.

The Notch pathway inhibitor stapled α-helical peptide derived from mastermind-like 1 (SAHM1) abrogates the hallmarks of allergic asthma.

KleinJan A, Tindemans I, Montgomery JE, Lukkes M, de Bruijn MJW, van Nimwegen M, Bergen I, Moellering RE, Hoogsteden HC, Boon L, Amsen D, Hendriks RW.

J Allergy Clin Immunol. 2018 Jul;142(1):76-85.e8. doi: 10.1016/j.jaci.2017.08.042. Epub 2017 Oct 27.

PMID:
29111218
35.

The Role of B Cells in Carriage and Clearance of Mycoplasma pneumoniae From the Respiratory Tract of Mice.

Meyer Sauteur PM, de Groot RCA, Estevão SC, Hoogenboezem T, de Bruijn ACJM, Sluijter M, de Bruijn MJW, De Kleer IM, van Haperen R, van den Brand JMA, Bogaert D, Fraaij PLA, Vink C, Hendriks RW, Samsom JN, Unger WWJ, van Rossum AMC.

J Infect Dis. 2018 Jan 4;217(2):298-309. doi: 10.1093/infdis/jix559.

36.

Cell lines generated from a chronic lymphocytic leukemia mouse model exhibit constitutive Btk and Akt signaling.

Singh SP, Pillai SY, de Bruijn MJW, Stadhouders R, Corneth OBJ, van den Ham HJ, Muggen A, van IJcken W, Slinger E, Kuil A, Spaargaren M, Kater AP, Langerak AW, Hendriks RW.

Oncotarget. 2017 May 26;8(42):71981-71995. doi: 10.18632/oncotarget.18234. eCollection 2017 Sep 22.

37.

Emerging roles of innate lymphoid cells in inflammatory diseases: Clinical implications.

Kortekaas Krohn I, Shikhagaie MM, Golebski K, Bernink JH, Breynaert C, Creyns B, Diamant Z, Fokkens WJ, Gevaert P, Hellings P, Hendriks RW, Klimek L, Mjösberg J, Morita H, Ogg GS, O'Mahony L, Schwarze J, Seys SF, Shamji MH, Bal SM.

Allergy. 2018 Apr;73(4):837-850. doi: 10.1111/all.13340. Epub 2017 Nov 22. Review.

PMID:
29069535
38.

TNF-α-induced protein 3 levels in lung dendritic cells instruct TH2 or TH17 cell differentiation in eosinophilic or neutrophilic asthma.

Vroman H, Bergen IM, van Hulst JAC, van Nimwegen M, van Uden D, Schuijs MJ, Pillai SY, van Loo G, Hammad H, Lambrecht BN, Hendriks RW, Kool M.

J Allergy Clin Immunol. 2018 May;141(5):1620-1633.e12. doi: 10.1016/j.jaci.2017.08.012. Epub 2017 Sep 6.

PMID:
28888782
39.

Dendritic Cell Subsets in Asthma: Impaired Tolerance or Exaggerated Inflammation?

Vroman H, Hendriks RW, Kool M.

Front Immunol. 2017 Aug 9;8:941. doi: 10.3389/fimmu.2017.00941. eCollection 2017. Review.

40.

Modified Vaccinia Virus Ankara Preferentially Targets Antigen Presenting Cells In Vitro, Ex Vivo and In Vivo.

Altenburg AF, van de Sandt CE, Li BWS, MacLoughlin RJ, Fouchier RAM, van Amerongen G, Volz A, Hendriks RW, de Swart RL, Sutter G, Rimmelzwaan GF, de Vries RD.

Sci Rep. 2017 Aug 17;7(1):8580. doi: 10.1038/s41598-017-08719-y.

41.

PPAR-γ promotes type 2 immune responses in allergy and nematode infection.

Chen T, Tibbitt CA, Feng X, Stark JM, Rohrbeck L, Rausch L, Sedimbi SK, Karlsson MCI, Lambrecht BN, Karlsson Hedestam GB, Hendriks RW, Chambers BJ, Nylén S, Coquet JM.

Sci Immunol. 2017 Mar 10;2(9). pii: eaal5196. doi: 10.1126/sciimmunol.aal5196.

PMID:
28783701
42.

Attenuation of Follicular Helper T Cell-Dependent B Cell Hyperactivity by Abatacept Treatment in Primary Sjögren's Syndrome.

Verstappen GM, Meiners PM, Corneth OBJ, Visser A, Arends S, Abdulahad WH, Hendriks RW, Vissink A, Kroese FGM, Bootsma H.

Arthritis Rheumatol. 2017 Sep;69(9):1850-1861. doi: 10.1002/art.40165. Epub 2017 Aug 13.

43.

Depletion of Tumor-Associated Macrophages with a CSF-1R Kinase Inhibitor Enhances Antitumor Immunity and Survival Induced by DC Immunotherapy.

Dammeijer F, Lievense LA, Kaijen-Lambers ME, van Nimwegen M, Bezemer K, Hegmans JP, van Hall T, Hendriks RW, Aerts JG.

Cancer Immunol Res. 2017 Jul;5(7):535-546. doi: 10.1158/2326-6066.CIR-16-0309. Epub 2017 May 23.

44.

Notch Signaling in T Helper Cell Subsets: Instructor or Unbiased Amplifier?

Tindemans I, Peeters MJW, Hendriks RW.

Front Immunol. 2017 Apr 18;8:419. doi: 10.3389/fimmu.2017.00419. eCollection 2017. Review.

45.

IL-21 Receptor Antagonist Inhibits Differentiation of B Cells toward Plasmablasts upon Alloantigen Stimulation.

de Leur K, Dor FJ, Dieterich M, van der Laan LJ, Hendriks RW, Baan CC.

Front Immunol. 2017 Mar 20;8:306. doi: 10.3389/fimmu.2017.00306. eCollection 2017.

46.

Stereotactic Ablative Radiotherapy Induces Peripheral T-Cell Activation in Patients with Early-Stage Lung Cancer.

de Goeje PL, Smit EF, Waasdorp C, Schram MTB, Kaijen-Lambers MEH, Bezemer K, de Mol M, Hartemink KJ, Nuyttens JJME, Maat APWM, Hegmans JPJJ, Hendriks RW, Senan S, Aerts JGJV.

Am J Respir Crit Care Med. 2017 Nov 1;196(9):1224-1227. doi: 10.1164/rccm.201610-2178LE. No abstract available.

PMID:
28345951
47.

Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

Lim AI, Li Y, Lopez-Lastra S, Stadhouders R, Paul F, Casrouge A, Serafini N, Puel A, Bustamante J, Surace L, Masse-Ranson G, David E, Strick-Marchand H, Le Bourhis L, Cocchi R, Topazio D, Graziano P, Muscarella LA, Rogge L, Norel X, Sallenave JM, Allez M, Graf T, Hendriks RW, Casanova JL, Amit I, Yssel H, Di Santo JP.

Cell. 2017 Mar 9;168(6):1086-1100.e10. doi: 10.1016/j.cell.2017.02.021.

48.

Distinct and Overlapping Functions of TEC Kinase and BTK in B Cell Receptor Signaling.

de Bruijn MJ, Rip J, van der Ploeg EK, van Greuningen LW, Ta VT, Kil LP, Langerak AW, Rimmelzwaan GF, Ellmeier W, Hendriks RW, Corneth OB.

J Immunol. 2017 Apr 15;198(8):3058-3068. doi: 10.4049/jimmunol.1601285. Epub 2017 Mar 8.

49.

Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease.

Corneth OBJ, Verstappen GMP, Paulissen SMJ, de Bruijn MJW, Rip J, Lukkes M, van Hamburg JP, Lubberts E, Bootsma H, Kroese FGM, Hendriks RW.

Arthritis Rheumatol. 2017 Jun;69(6):1313-1324. doi: 10.1002/art.40059. Epub 2017 May 10.

50.

Notch signaling in T cells is essential for allergic airway inflammation, but expression of the Notch ligands Jagged 1 and Jagged 2 on dendritic cells is dispensable.

Tindemans I, Lukkes M, de Bruijn MJW, Li BWS, van Nimwegen M, Amsen D, KleinJan A, Hendriks RW.

J Allergy Clin Immunol. 2017 Oct;140(4):1079-1089. doi: 10.1016/j.jaci.2016.11.046. Epub 2017 Jan 19.

PMID:
28111308

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