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A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation.

Minutti CM, Modak RV, Macdonald F, Li F, Smyth DJ, Dorward DA, Blair N, Husovsky C, Muir A, Giampazolias E, Dobie R, Maizels RM, Kendall TJ, Griggs DW, Kopf M, Henderson NC, Zaiss DM.

Immunity. 2019 Feb 6. pii: S1074-7613(19)30031-7. doi: 10.1016/j.immuni.2019.01.008. [Epub ahead of print]


An orally active galectin-3 antagonist inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade.

Vuong L, Kouverianou E, Rooney CM, McHugh BJ, Howie SE, Gregory CD, Forbes SJ, Henderson NC, Zetterberg FR, Nilsson UJ, Leffler H, Ford P, Pederson A, Gravelle L, Tantawi S, Schambye H, Sethi T, Mackinnon AC.

Cancer Res. 2019 Jan 23. pii: canres.2244.2018. doi: 10.1158/0008-5472.CAN-18-2244. [Epub ahead of print]


Fibroblast-specific integrin-alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis.

Sciurba JC, Gieseck RL, Jiwrajka N, White SD, Karmele EP, Redes J, Vannella KM, Henderson NC, Wynn TA, Hart KM.

J Pathol. 2018 Dec 7. doi: 10.1002/path.5215. [Epub ahead of print]


Staphylococcus aureus endocarditis associated with injecting new psychoactive substances.

Joshi SS, Henderson N, Griffith DJ, Henriksen PA, Denvir MA, Macsween KF, Mackintosh CL, Inverarity D.

J R Coll Physicians Edinb. 2018 Dec;48(4):304-310. doi: 10.4997/JRCPE.2018.404.


2018 White Paper on Recent Issues in Bioanalysis: focus on flow cytometry, gene therapy, cut points and key clarifications on BAV (Part 3 - LBA/cell-based assays: immunogenicity, biomarkers and PK assays).

Stevenson L, Richards S, Pillutla R, Torri A, Kamerud J, Mehta D, Keller S, Purushothama S, Gorovits B, Litwin V, Stebbins C, Marini J, Beaver C, Sperinde G, Siguenza P, Staack RF, Qiu Y, Amaravadi L, Amur S, Fleener CA, Baltrukonis D, Catlett I, Cherry E, Chung S, Cludts I, Donato LD, Fischer S, Fraser S, Garofolo F, Green C, Gunn G, Haidar S, Haulenbeek J, Henderson N, Hopper S, Ishii-Watabe A, Islam R, Janelsins B, Jawa V, Kakkanaiah V, Kamondi S, Kolaitis G, Kubiak RJ, Kumar S, Kurki P, Liang M, Liu P, Maxfield K, Myler H, Palackal N, Palmer R, Pedras-Vasconcelos J, Piccoli S, Rhyne P, Saito Y, Savoie N, Schick E, Schweighardt B, Shih J, Song A, Sriraman P, Staelens L, Sumner G, Sun Y, Ullmann M, Verthelyi D, Wadhwa M, Wang YM, Xu Y, Yan H, Yang TY, Zeng R.

Bioanalysis. 2018 Nov 29. doi: 10.4155/bio-2018-0287. [Epub ahead of print]


2018 White Paper on Recent Issues in Bioanalysis: 'A global bioanalytical community perspective on last decade of incurred samples reanalysis (ISR)' (Part 1 - small molecule regulated bioanalysis, small molecule biomarkers, peptides & oligonucleotide bioanalysis).

Welink J, Xu Y, Yang E, Wilson A, Henderson N, Luo L, Fraser S, Kavita U, Musuku A, James C, Fraier D, Zhang Y, Goykhman D, Summerfield S, Woolf E, Verhaeghe T, Hughes N, Behling A, Brown K, Bulychev A, Buonarati M, Cherry E, Cho SJ, Cludts I, Dillen L, Dodge R, Edmison A, Garofolo F, Green R, Haidar S, Hottenstein C, Ishii-Watabe A, Jang HG, Ji A, Jones B, Kassim S, Ma M, Lima Santos GM, Norris DA, Owen T, Piccoli S, Ramanathan R, Röhl I, Rosenbaum AI, Saito Y, Sangster T, Savoie N, Stebbins C, Sydor J, de Merbel NV, Verthelyi D, Vinter S, Whale E.

Bioanalysis. 2018 Nov 1;10(22):1781-1801. doi: 10.4155/bio-2018-0268. Epub 2018 Nov 29.


Loss of Integrin αvβ8 in Murine Hepatocytes Accelerates Liver Regeneration.

Greenhalgh SN, Matchett KP, Taylor RS, Huang K, Li JT, Saeteurn K, Donnelly MC, Simpson EEM, Pollack JL, Atakilit A, Simpson KJ, Maher JJ, Iredale JP, Sheppard D, Henderson NC.

Am J Pathol. 2019 Feb;189(2):258-271. doi: 10.1016/j.ajpath.2018.10.007. Epub 2018 Nov 16.


Unravelling atherosclerotic heterogeneity by single cell RNA sequencing.

McCracken IR, Taylor RS, Henderson NC, Sluimer JC, Baker AH.

Curr Opin Lipidol. 2018 Dec;29(6):488-489. doi: 10.1097/MOL.0000000000000559. No abstract available.


Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD.

Du M, Yuan Z, Yu H, Henderson N, Sarowar S, Zhao G, Werneburg GT, Thanassi DG, Li H.

Nature. 2018 Oct;562(7727):444-447. doi: 10.1038/s41586-018-0587-z. Epub 2018 Oct 3.


Use of Thromboelastography to Predict Thrombotic Complications in Pediatric and Neonatal Extracorporeal Membranous Oxygenation.

Henderson N, Sullivan JE, Myers J, Wells T, Calhoun A, Berkenbosch J, Tzanetos DT.

J Extra Corpor Technol. 2018 Sep;50(3):149-154.


Lessons on Patient and Stakeholder Engagement Strategies for Pipeline to Proposal Awards.

Wennerstrom A, Springgate BF, Jones F, Meyers D, Henderson N, Brown A, Niyogi A, Martin D, Smith J 3rd, Kirkland AL, Jones L, Norris KC.

Ethn Dis. 2018 Sep 6;28(Suppl 2):303-310. doi: 10.18865/ed.28.S2.303. eCollection 2018.


AR(1) latent class models for longitudinal count data.

Henderson NC, Rathouz PJ.

Stat Med. 2018 Dec 20;37(29):4441-4456. doi: 10.1002/sim.7931. Epub 2018 Aug 21.


Individualized treatment effects with censored data via fully nonparametric Bayesian accelerated failure time models.

Henderson NC, Louis TA, Rosner GL, Varadhan R.

Biostatistics. 2018 Jul 19. doi: 10.1093/biostatistics/kxy028. [Epub ahead of print]


Preclinical evaluation of point-of-care prothrombin time as a biomarker test to guide prothrombin replacement therapy in coagulopathic bleeding.

Balendran CA, Henderson N, Olsson M, Lövgren A, Hansson KM.

Res Pract Thromb Haemost. 2017 Aug 2;1(2):252-258. doi: 10.1002/rth2.12027. eCollection 2017 Oct.


EphBs and ephrin-Bs: Trans-synaptic organizers of synapse development and function.

Henderson NT, Dalva MB.

Mol Cell Neurosci. 2018 Sep;91:108-121. doi: 10.1016/j.mcn.2018.07.002. Epub 2018 Jul 19. Review.


The colorectal surgeon's personality may influence the rectal anastomotic decision.

Moug SJ, Henderson N, Tiernan J, Bisset CN, Ferguson E, Harji D, Maxwell-Armstrong C, MacDermid E, Acheson AG, Steele RJC, Fearnhead NS; Edinburgh Delphi Collaborative Group.

Colorectal Dis. 2018 Nov;20(11):970-980. doi: 10.1111/codi.14293. Epub 2018 Jul 5.


Synaptic nanomodules underlie the organization and plasticity of spine synapses.

Hruska M, Henderson N, Le Marchand SJ, Jafri H, Dalva MB.

Nat Neurosci. 2018 May;21(5):671-682. doi: 10.1038/s41593-018-0138-9. Epub 2018 Apr 23.


Mapping and understanding exclusion.

Henderson N.

Lancet. 2018 Apr 14;391(10129):1480-1481. doi: 10.1016/S0140-6736(18)30571-3. No abstract available.


Considerations when assessing heterogeneity of treatment effect in patient-centered outcomes research.

Lesko CR, Henderson NC, Varadhan R.

J Clin Epidemiol. 2018 Aug;100:22-31. doi: 10.1016/j.jclinepi.2018.04.005. Epub 2018 Apr 11. Review.


A Context-Dependent Role for αv Integrins in Regulatory T Cell Accumulation at Sites of Inflammation.

Mair I, Zandee SEJ, Toor IS, Saul L, McPherson RC, Leech MD, Smyth DJ, O'Connor RA, Henderson NC, Anderton SM.

Front Immunol. 2018 Feb 26;9:264. doi: 10.3389/fimmu.2018.00264. eCollection 2018.


Understanding remote Aboriginal drug and alcohol residential rehabilitation clients: Who attends, who leaves and who stays?

Munro A, Shakeshaft A, Breen C, Clare P, Allan J, Henderson N.

Drug Alcohol Rev. 2018 Apr;37 Suppl 1:S404-S414. doi: 10.1111/dar.12656. Epub 2018 Jan 18.


The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury.

Campana L, Starkey Lewis PJ, Pellicoro A, Aucott RL, Man J, O'Duibhir E, Mok SE, Ferreira-Gonzalez S, Livingstone E, Greenhalgh SN, Hull KL, Kendall TJ, Vernimmen D, Henderson NC, Boulter L, Gregory CD, Feng Y, Anderton SM, Forbes SJ, Iredale JP.

J Immunol. 2018 Feb 1;200(3):1169-1187. doi: 10.4049/jimmunol.1701247. Epub 2017 Dec 20.


11Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis.

Zou X, Ramachandran P, Kendall TJ, Pellicoro A, Dora E, Aucott RL, Manwani K, Man TY, Chapman KE, Henderson NC, Forbes SJ, Webster SP, Iredale JP, Walker BR, Michailidou Z.

Hepatology. 2018 Jun;67(6):2167-2181. doi: 10.1002/hep.29734. Epub 2018 Feb 22.


Comparison Between Total IgG, C1q, and C3d Single Antigen Bead Assays in Detecting Class I Complement-Binding Anti-HLA Antibodies.

Moreno Gonzales MA, Mitema DG, Smith BH, Schinstock CA, Stegall MD, Wakefield LL, Henderson NA, DeGoey SR, Kreuter JD, Gandhi MJ.

Transplant Proc. 2017 Nov;49(9):2031-2035. doi: 10.1016/j.transproceed.2017.09.040.


αv integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis.

Murray IR, Gonzalez ZN, Baily J, Dobie R, Wallace RJ, Mackinnon AC, Smith JR, Greenhalgh SN, Thompson AI, Conroy KP, Griggs DW, Ruminski PG, Gray GA, Singh M, Campbell MA, Kendall TJ, Dai J, Li Y, Iredale JP, Simpson H, Huard J, Péault B, Henderson NC.

Nat Commun. 2017 Oct 24;8(1):1118. doi: 10.1038/s41467-017-01097-z.


Extracellular phosphorylation of a receptor tyrosine kinase controls synaptic localization of NMDA receptors and regulates pathological pain.

Hanamura K, Washburn HR, Sheffler-Collins SI, Xia NL, Henderson N, Tillu DV, Hassler S, Spellman DS, Zhang G, Neubert TA, Price TJ, Dalva MB.

PLoS Biol. 2017 Jul 18;15(7):e2002457. doi: 10.1371/journal.pbio.2002457. eCollection 2017 Jul.


Determining myeloperoxidase activity and protein concentration in a single assay: Utility in biomarker and therapeutic studies.

Russell M, Prokoph N, Henderson N, Eketjäll S, Balendran CA, Michaëlsson E, Fidock M, Hughes G.

J Immunol Methods. 2017 Oct;449:76-79. doi: 10.1016/j.jim.2017.07.003. Epub 2017 Jul 13.


'Top, bottom, versatile': narratives of sexual practices in gay relationships in the Cape Metropole, South Africa.

Henderson NJ.

Cult Health Sex. 2018 Nov;20(11):1145-1156. doi: 10.1080/13691058.2017.1347715. Epub 2017 Jul 13.


Assessing the impact of a temporary class drug order on ethylphenidate-related infections among people who inject drugs in Lothian, Scotland: an interrupted time-series analysis.

Yeung A, Weir A, Austin H, Morrison K, Inverarity D, Sherval J, Henderson N, Joshi S, Ure R, McAuley A.

Addiction. 2017 Oct;112(10):1799-1807. doi: 10.1111/add.13898. Epub 2017 Jul 11.


Antifibrotics in chronic liver disease: tractable targets and translational challenges.

Ramachandran P, Henderson NC.

Lancet Gastroenterol Hepatol. 2016 Dec;1(4):328-340. doi: 10.1016/S2468-1253(16)30110-8. Epub 2016 Nov 10. Review.


Medical Disease or Moral Defect? Stigma Attribution and Cultural Models of Addiction Causality in a University Population.

Henderson NL, Dressler WW.

Cult Med Psychiatry. 2017 Dec;41(4):480-498. doi: 10.1007/s11013-017-9531-1.


Bringing it all back home: Understanding the medical difficulties encountered by newly released prisoners in New Orleans, Louisiana - a qualitative study.

Vail WL, Niyogi A, Henderson N, Wennerstrom A.

Health Soc Care Community. 2017 Jul;25(4):1448-1458. doi: 10.1111/hsc.12445. Epub 2017 Mar 28.


Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis.

King A, Houlihan DD, Kavanagh D, Haldar D, Luu N, Owen A, Suresh S, Than NN, Reynolds G, Penny J, Sumption H, Ramachandran P, Henderson NC, Kalia N, Frampton J, Adams DH, Newsome PN.

Gastroenterology. 2017 Jul;153(1):233-248.e16. doi: 10.1053/j.gastro.2017.03.022. Epub 2017 Mar 28.


Logistic Regression Likelihood Ratio Test Analysis for Detecting Signals of Adverse Events in Post-market Safety Surveillance.

Nam K, Henderson NC, Rohan P, Woo EJ, Russek-Cohen E.

J Biopharm Stat. 2017;27(6):990-1008. doi: 10.1080/10543406.2017.1295250. Epub 2017 Mar 27.


Galectin-3, histone deacetylases, and Hedgehog signaling: Possible convergent targets in schistosomiasis-induced liver fibrosis.

de Oliveira FL, Carneiro K, Brito JM, Cabanel M, Pereira JX, Paiva LA, Syn W, Henderson NC, El-Cheikh MC.

PLoS Negl Trop Dis. 2017 Feb 23;11(2):e0005137. doi: 10.1371/journal.pntd.0005137. eCollection 2017 Feb. Review.


Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice.

Delhove JM, Buckley SM, Perocheau DP, Karda R, Arbuthnot P, Henderson NC, Waddington SN, McKay TR.

Sci Rep. 2017 Feb 3;7:41874. doi: 10.1038/srep41874.


Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver.

Gamal W, Treskes P, Samuel K, Sullivan GJ, Siller R, Srsen V, Morgan K, Bryans A, Kozlowska A, Koulovasilopoulos A, Underwood I, Smith S, Del-Pozo J, Moss S, Thompson AI, Henderson NC, Hayes PC, Plevris JN, Bagnaninchi PO, Nelson LJ.

Sci Rep. 2017 Jan 30;7:37541. doi: 10.1038/srep37541.


Bayesian analysis of heterogeneous treatment effects for patient-centered outcomes research.

Henderson NC, Louis TA, Wang C, Varadhan R.

Health Serv Outcomes Res Methodol. 2016;16(4):213-233. Epub 2016 Sep 20.


Postnatal Pancraniosynostosis in a Patient With Infantile Hypophosphatasia.

Nahabet EH, Gatherwright J, Vockley J, Henderson N, Tomei KL, Grigorian AP, Kaminski B, Bass N, Selman WR, Lakin GE.

Cleft Palate Craniofac J. 2016 Nov;53(6):741-744. Epub 2015 Jul 14.


A Letter to the Editor.

Rutherford C, Couves A, Henderson N, Kamya S, Ong K, Bisset C, Vella M, Renwick A.

Ann Surg. 2018 Feb;267(2):e39. doi: 10.1097/SLA.0000000000002052. No abstract available.


Correction: Allosteric signalling in the outer membrane translocation domain of PapC usher.

Farabella I, Pham T, Henderson NS, Geibel S, Phan G, Thanassi DG, Delcour AH, Waksman G, Topf M.

Elife. 2016 Sep 27;5. pii: e21585. doi: 10.7554/eLife.21585. No abstract available.


Mesenchymal stromal cells and liver fibrosis: a complicated relationship.

Haldar D, Henderson NC, Hirschfield G, Newsome PN.

FASEB J. 2016 Dec;30(12):3905-3928. Epub 2016 Sep 6. Review.


Outcomes of endoscopic retrograde cholangiopancreatography: a series from a provincial New Zealand hospital.

Richards S, Kyle S, White C, El-Haddawi F, Farrant G, Henderson N, Fancourt M, Gilkison W.

ANZ J Surg. 2018 Mar;88(3):207-211. doi: 10.1111/ans.13734. Epub 2016 Sep 6.


Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies.

Randall K, Henderson N, Reens J, Eckersley S, Nyström AC, South MC, Balendran CA, Böttcher G, Hughes G, Price SA.

PLoS One. 2016 Sep 6;11(9):e0162076. doi: 10.1371/journal.pone.0162076. eCollection 2016.


Skeletal and cardiac muscle pericytes: Functions and therapeutic potential.

Murray IR, Baily JE, Chen WCW, Dar A, Gonzalez ZN, Jensen AR, Petrigliano FA, Deb A, Henderson NC.

Pharmacol Ther. 2017 Mar;171:65-74. doi: 10.1016/j.pharmthera.2016.09.005. Epub 2016 Sep 2. Review.


Making the cut: improved ranking and selection for large-scale inference.

Henderson NC, Newton MA.

J R Stat Soc Series B Stat Methodol. 2016 Sep;78(4):781-804. Epub 2015 Nov 8.


PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis.

Martin K, Pritchett J, Llewellyn J, Mullan AF, Athwal VS, Dobie R, Harvey E, Zeef L, Farrow S, Streuli C, Henderson NC, Friedman SL, Hanley NA, Piper Hanley K.

Nat Commun. 2016 Aug 18;7:12502. doi: 10.1038/ncomms12502.


Homing in on the hepatic scar: recent advances in cell-specific targeting of liver fibrosis.

Dobie R, Henderson NC.

F1000Res. 2016 Jul 19;5. pii: F1000 Faculty Rev-1749. doi: 10.12688/f1000research.8822.1. eCollection 2016. Review.


International collaborations in learning and teaching: perspectives from a visiting professorship.

Spring H, Kunkel M, Gilman I, Henderson N, White J.

Health Info Libr J. 2016 Sep;33(3):249-54. doi: 10.1111/hir.12148.


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