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Items: 1 to 50 of 234

1.

Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.

McNicoll F, Kühnel A, Biswas U, Hempel K, Whelan G, Eichele G, Jessberger R.

Life Sci Alliance. 2020 Feb 12;3(3). pii: e201900564. doi: 10.26508/lsa.201900564. Print 2020 Mar.

2.

Refinement of the rodent pentylenetetrazole proconvulsion assay, which is a good predictor of convulsions in repeat-dose toxicology studies.

Breidenbach L, Hempel K, Mittelstadt SW, Lynch JJ 3rd.

J Pharmacol Toxicol Methods. 2020 Jan - Feb;101:106653. doi: 10.1016/j.vascn.2019.106653. Epub 2019 Nov 12.

PMID:
31730935
3.

Exploratory EEG studies for the assessment of neurological liabilities in conscious dogs in early drug development.

Breidenbach L, Potschka H, Hempel K.

J Pharmacol Toxicol Methods. 2019 Jul - Aug;98:106581. doi: 10.1016/j.vascn.2019.106581. Epub 2019 May 15.

PMID:
31102738
4.

Colitis, Collagenous And Lymphocytic.

Hempel KA, Sharma AV.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-.
2019 Jun 4.

5.

Variability of non-clinical behavioral CNS safety assessment: An intercompany comparison.

Himmel HM; Irwin/FOB Consortium Members, Delaunois A, Deurinck M, Dinklo T, Eriksson Faelker TM, Habermann C, Heers C, Hempel K, Lorenz H, Rosch A, Schauerte H, Teuns G, Traebert M, van Amsterdam C, van der Linde H.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106571. doi: 10.1016/j.vascn.2019.03.002. Epub 2019 Mar 27.

PMID:
30928509
6.

Total Synthesis of Pericoannosin A.

Lücke D, Linne Y, Hempel K, Kalesse M.

Org Lett. 2018 Aug 3;20(15):4475-4477. doi: 10.1021/acs.orglett.8b01768. Epub 2018 Jul 13.

PMID:
30003789
7.

Dropped-head syndrome in a patient under treatment with the MEK inhibitor trametinib for NRAS-mutated metastatic melanoma.

Kleemann J, Hrgovic I, Hempel K, Kaufmann R, Meissner M.

Clin Exp Dermatol. 2018 Mar;43(2):195-196. doi: 10.1111/ced.13297. Epub 2017 Oct 11. No abstract available.

PMID:
29023842
8.

Measuring drug absorption improves interpretation of behavioral responses in a larval zebrafish locomotor assay for predicting seizure liability.

Cassar S, Breidenbach L, Olson A, Huang X, Britton H, Woody C, Sancheti P, Stolarik D, Wicke K, Hempel K, LeRoy B.

J Pharmacol Toxicol Methods. 2017 Nov;88(Pt 1):56-63. doi: 10.1016/j.vascn.2017.07.002. Epub 2017 Jul 13.

PMID:
28712933
9.

Equilibrium and ultrafast kinetic studies manipulating electron transfer: A short-lived flavin semiquinone is not sufficient for electron bifurcation.

Hoben JP, Lubner CE, Ratzloff MW, Schut GJ, Nguyen DMN, Hempel KW, Adams MWW, King PW, Miller AF.

J Biol Chem. 2017 Aug 25;292(34):14039-14049. doi: 10.1074/jbc.M117.794214. Epub 2017 Jun 14.

10.

Image-based modeling and scoring of Howell-Jolly Bodies in human erythrocytes.

Angay O, Friedrich M, Pinnecker J, Hintzsche H, Stopper H, Hempel K, Heinze KG.

Cytometry A. 2018 Mar;93(3):305-313. doi: 10.1002/cyto.a.23123. Epub 2017 May 24.

11.

Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis.

Biswas U, Hempel K, Llano E, Pendas A, Jessberger R.

PLoS Genet. 2016 Oct 28;12(10):e1006389. doi: 10.1371/journal.pgen.1006389. eCollection 2016 Oct.

12.

A retrospective evaluation of species-specific sensitivity for neurological signs in toxicological studies: Is the dog more sensitive than the non-human primate?

Backes K, Lorenz H, Laplanche L, Hudzik TJ, Potschka H, Hempel K.

Toxicol Lett. 2016 Jan 22;243:78-87. doi: 10.1016/j.toxlet.2015.12.007. Epub 2015 Dec 28.

PMID:
26732424
13.

A century of transitions in New York City's measles dynamics.

Hempel K, Earn DJ.

J R Soc Interface. 2015 May 6;12(106). pii: 20150024. doi: 10.1098/rsif.2015.0024.

14.

A specific LSD1/KDM1A isoform regulates neuronal differentiation through H3K9 demethylation.

Laurent B, Ruitu L, Murn J, Hempel K, Ferrao R, Xiang Y, Liu S, Garcia BA, Wu H, Wu F, Steen H, Shi Y.

Mol Cell. 2015 Mar 19;57(6):957-970. doi: 10.1016/j.molcel.2015.01.010. Epub 2015 Feb 12.

15.

The histone demethylase LSD1/KDM1A promotes the DNA damage response.

Mosammaparast N, Kim H, Laurent B, Zhao Y, Lim HJ, Majid MC, Dango S, Luo Y, Hempel K, Sowa ME, Gygi SP, Steen H, Harper JW, Yankner B, Shi Y.

J Cell Biol. 2013 Nov 11;203(3):457-70. doi: 10.1083/jcb.201302092.

16.

Frequency of transferrin receptor positive reticulocytes (TF-Ret) in blood as an indicator of total-body radiation exposure: a pilot study in nuclear medicine patients.

Hempel K, Haenscheid H, Biko J, Hategan M, Kaiser F, Kreissl M, Lorenz R, Samnick S, Schirbel A, Varazashvili L, Verchenya S, Reiners C.

Radiat Res. 2012 Nov;178(5):481-8. doi: 10.1667/RR2818.1. Epub 2012 Oct 2.

PMID:
23030782
17.

Cell surface proteome of the marine planctomycete Rhodopirellula baltica.

Voigt B, Hieu CX, Hempel K, Becher D, Schlüter R, Teeling H, Glöckner FO, Amann R, Hecker M, Schweder T.

Proteomics. 2012 Jun;12(11):1781-91. doi: 10.1002/pmic.201100512.

PMID:
22623273
18.

Metaproteomics of a gutless marine worm and its symbiotic microbial community reveal unusual pathways for carbon and energy use.

Kleiner M, Wentrup C, Lott C, Teeling H, Wetzel S, Young J, Chang YJ, Shah M, VerBerkmoes NC, Zarzycki J, Fuchs G, Markert S, Hempel K, Voigt B, Becher D, Liebeke M, Lalk M, Albrecht D, Hecker M, Schweder T, Dubilier N.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):E1173-82. doi: 10.1073/pnas.1121198109. Epub 2012 Apr 18.

19.

Soluplus® as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo.

Linn M, Collnot EM, Djuric D, Hempel K, Fabian E, Kolter K, Lehr CM.

Eur J Pharm Sci. 2012 Feb 14;45(3):336-43. doi: 10.1016/j.ejps.2011.11.025. Epub 2011 Dec 8.

PMID:
22172603
20.

Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells.

Glassmeier G, Hempel K, Wulfsen I, Bauer CK, Schumacher U, Schwarz JR.

Pflugers Arch. 2012 Feb;463(2):365-76. doi: 10.1007/s00424-011-1045-z. Epub 2011 Nov 11.

21.

Refinement and reduction of acute oral toxicity testing: a critical review of the use of cytotoxicity data.

Schrage A, Hempel K, Schulz M, Kolle SN, van Ravenzwaay B, Landsiedel R.

Altern Lab Anim. 2011 Jul;39(3):273-95. Review.

PMID:
21777041
22.

Activity control of the ClpC adaptor McsB in Bacillus subtilis.

Elsholz AK, Hempel K, Michalik S, Gronau K, Becher D, Hecker M, Gerth U.

J Bacteriol. 2011 Aug;193(15):3887-93. doi: 10.1128/JB.00079-11. Epub 2011 May 27.

23.

Quantitative proteomic view on secreted, cell surface-associated, and cytoplasmic proteins of the methicillin-resistant human pathogen Staphylococcus aureus under iron-limited conditions.

Hempel K, Herbst FA, Moche M, Hecker M, Becher D.

J Proteome Res. 2011 Apr 1;10(4):1657-66. doi: 10.1021/pr1009838. Epub 2011 Mar 16.

PMID:
21323324
24.

CtsR inactivation during thiol-specific stress in low GC, Gram+ bacteria.

Elsholz AK, Hempel K, Pöther DC, Becher D, Hecker M, Gerth U.

Mol Microbiol. 2011 Feb;79(3):772-85. doi: 10.1111/j.1365-2958.2010.07489.x. Epub 2011 Jan 5.

25.

Profiling the surfacome of Staphylococcus aureus.

Dreisbach A, Hempel K, Buist G, Hecker M, Becher D, van Dijl JM.

Proteomics. 2010 Sep;10(17):3082-96. doi: 10.1002/pmic.201000062.

PMID:
20662103
26.

Quantitative cell surface proteome profiling for SigB-dependent protein expression in the human pathogen Staphylococcus aureus via biotinylation approach.

Hempel K, Pané-Farré J, Otto A, Sievers S, Hecker M, Becher D.

J Proteome Res. 2010 Mar 5;9(3):1579-90. doi: 10.1021/pr901143a.

PMID:
20108986
27.

A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.

Becher D, Hempel K, Sievers S, Zühlke D, Pané-Farré J, Otto A, Fuchs S, Albrecht D, Bernhardt J, Engelmann S, Völker U, van Dijl JM, Hecker M.

PLoS One. 2009 Dec 4;4(12):e8176. doi: 10.1371/journal.pone.0008176.

28.

Solid-phase synthesis of peptide libraries combining alpha-amino acids with inorganic and organic chromophores.

Heinze K, Hempel K.

Chemistry. 2009;15(6):1346-58. doi: 10.1002/chem.200801864.

PMID:
19123215
29.

Analysis of ultra acidic proteins by the use of anodic acidic gels.

Hempel K, Rosen R, Becher D, Büttner K, Hecker M, Ron EZ.

Anal Biochem. 2009 Feb 15;385(2):208-14. doi: 10.1016/j.ab.2008.11.013. Epub 2008 Nov 19.

PMID:
19084495
30.

Solid-phase synthesis of transition-metal complexes.

Heinze K, Beckmann M, Hempel K.

Chemistry. 2008;14(31):9468-80. doi: 10.1002/chem.200800697. Review.

PMID:
18613162
31.

Toxicological properties of metaflumizone.

Hempel K, Hess FG, Bögi C, Fabian E, Hellwig J, Fegert I.

Vet Parasitol. 2007 Dec 15;150(3):190-5. Epub 2007 Oct 22.

PMID:
17933467
32.

Evaluation of the reticulocyte micronucleus assay in patients treated with radioiodine for thyroid cancer.

Grawé J, Biko J, Lorenz R, Reiners C, Stopper H, Vershenya S, Vukicevic V, Hempel K.

Mutat Res. 2005 May 2;583(1):12-25.

PMID:
15866462
33.

Pilot study for comparison of reticulocyte-micronulei with lymphocyte-micronuclei in human biomonitoring.

Stopper H, Hempel K, Reiners C, Vershenya S, Lorenz R, Vukicevic V, Heidland A, Grawe J.

Toxicol Lett. 2005 Apr 28;156(3):351-60. Epub 2005 Jan 18.

PMID:
15763634
34.

Dose response for T-cell receptor (TCR) mutants in patients repeatedly treated with 131I for thyroid cancer.

Vershenya S, Biko J, Drozd V, Lorenz R, Reiners C, Hempel K.

Mutat Res. 2004 Apr 14;548(1-2):27-33.

PMID:
15063133
36.
37.

[Left-sided thoracic pain in a 56-year old man followed by double vision and paresthesias of the left hand].

Grosche S, Schöne W, Borgmann H, Hempel K, Schubert C, Wihsgott C.

Internist (Berl). 2000 Jul;41(7):665-8. German. No abstract available.

PMID:
10929254
38.

[Medical-surgical intuition and professional policy].

Hempel K.

Zentralbl Chir. 1999;124 Suppl 3:39-41. German.

PMID:
10596072
39.

Use of the recursion formula of the Gompertz function for the quantitation of PCR-amplified templates.

Schlereth W, Bassukas ID, Deubel W, Lorenz R, Hempel K.

Int J Mol Med. 1998 Feb;1(2):463-7.

PMID:
9852251
40.

[The new commander is on board!].

Hempel K.

Chirurg. 1998 Aug;69(8):suppl 241-2. German. No abstract available.

PMID:
9782403
41.

[16 years president of the Professional Organization of German Physicians].

Hempel K.

Chirurg. 1998 Jun;69(6):suppl 171-3. German. No abstract available.

PMID:
9676373
42.

[The status of perioperative pain therapy in Germany. Results of a representative, anonymous survey of 1,000 surgical clinic. Pain Study Group].

Neugebauer E, Hempel K, Sauerland S, Lempa M, Koch G.

Chirurg. 1998 Apr;69(4):461-6. German.

PMID:
9612634
43.

[Indications for teleconsultation in surgery].

Feussner H, Hempel K, Siewert JR.

Chirurg. 1997 Dec;68(12):suppl 363-5. German. No abstract available.

PMID:
9483349
44.

[Interest groups].

Hempel K.

Chirurg. 1997 May;68(5):Suppl 121-2. German. No abstract available.

PMID:
9303826
45.

[Professional liability insurance].

Hempel K, Weissauer W.

Chirurg. 1997 Apr;68(4):suppl 108-9. German. No abstract available.

PMID:
9206620
46.

[Principles of perioperative responsibility].

Hempel K.

Chirurg. 1997 Mar;68(3):suppl 82-3. German. No abstract available.

PMID:
9198557
47.

[Retrospect--prospects].

Hempel K, Bauch J.

Chirurg. 1997 Jan;68(1):Suppl 1-2. German. No abstract available.

PMID:
9132338
48.
49.

[Who is responsible for pain therapy?].

Hempel K, Weissauer W.

Chirurg. 1996 Jul;67(7):663-4. German. No abstract available.

PMID:
8925697
50.

[Holding the physician responsible--limits of human capacity].

Hempel K.

Chirurg. 1996 Jul;67(7):suppl 159-62. German. No abstract available.

PMID:
8925695

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