Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 193

1.

The challenge to define a relevant change in medication appropriateness index score in older adults - An approach.

Krisch L, Mahlknecht A, Bauer U, Nestler N, Hempel G, Osterbrink J, Flamm M.

Br J Clin Pharmacol. 2020 Jan 12. doi: 10.1111/bcp.14167. [Epub ahead of print] No abstract available.

PMID:
31930550
2.

Detection of posttraumatic pneumothorax using electrical impedance tomography-An observer-blinded study in pigs with blunt chest trauma.

Girrbach F, Landeck T, Schneider D, Reske SU, Hempel G, Hammermüller S, Gottschaldt U, Salz P, Noreikat K, Stehr SN, Wrigge H, Reske AW.

PLoS One. 2020 Jan 10;15(1):e0227518. doi: 10.1371/journal.pone.0227518. eCollection 2020.

3.

Pharmacotherapy in Children and Adolescents: Oncology.

Hempel G.

Handb Exp Pharmacol. 2019 Dec 3. doi: 10.1007/164_2019_306. [Epub ahead of print]

PMID:
31792677
4.

Pharmacokinetics of Micafungin in Critically Ill Patients.

Gastine S, Lanckohr C, Blessou M, Horn D, Fobker M, Bause D, Hempel G, Ellger B.

Sci Rep. 2019 Nov 28;9(1):17741. doi: 10.1038/s41598-019-53093-6.

5.

Thoracotomy for emergency repair of iatrogenic tracheal rupture: single center analysis of perioperative management and outcomes.

Struck MF, Hempel G, Pietsch UC, Broschewitz J, Eichfeld U, Werdehausen R, Krämer S.

BMC Anesthesiol. 2019 Oct 27;19(1):194. doi: 10.1186/s12871-019-0869-5.

6.
7.

Impact of training and structured medication review on medication appropriateness and patient-related outcomes in nursing homes: results from the interventional study InTherAKT.

Mahlknecht A, Krisch L, Nestler N, Bauer U, Letz N, Zenz D, Schuler J, Fährmann L, Hempel G, Flamm M, Osterbrink J.

BMC Geriatr. 2019 Sep 18;19(1):257. doi: 10.1186/s12877-019-1263-3.

8.

Impact of dose and duration of therapy on dexamethasone pharmacokinetics in childhood acute lymphoblastic leukaemia-a report from the UKALL 2011 trial.

Jackson RK, Liebich M, Berry P, Errington J, Liu J, Parker C, Moppett J, Samarasinghe S, Hough R, Rowntree C, Goulden NJ, Vora A, Kearns PR, Saha V, Hempel G, Irving JAE, Veal GJ.

Eur J Cancer. 2019 Oct;120:75-85. doi: 10.1016/j.ejca.2019.07.026. Epub 2019 Sep 6.

PMID:
31499383
9.

Physiologically based pharmacokinetic evaluation of cefuroxime in perioperative antibiotic prophylaxis.

Rimmler C, Lanckohr C, Akamp C, Horn D, Fobker M, Wiebe K, Redwan B, Ellger B, Koeck R, Hempel G.

Br J Clin Pharmacol. 2019 Dec;85(12):2864-2877. doi: 10.1111/bcp.14121. Epub 2019 Dec 15.

10.

Continuous infusion of physostigmine in patients with perioperative septic shock: A pharmacokinetic/pharmacodynamic study with population pharmacokinetic modeling.

Pinder N, Zimmermann JB, Gastine S, Würthwein G, Hempel G, Bruckner T, Hoppe-Tichy T, Weigand MA, Swoboda S.

Biomed Pharmacother. 2019 Oct;118:109318. doi: 10.1016/j.biopha.2019.109318. Epub 2019 Aug 6.

11.

Physiologically Based Pharmacokinetic Modelling to Describe the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone According to Cytochrome P450 2D6 Phenotypes.

Kneller LA, Abad-Santos F, Hempel G.

Clin Pharmacokinet. 2019 Jul 30. doi: 10.1007/s40262-019-00793-x. [Epub ahead of print]

PMID:
31359271
12.

Microbial and abiotic controls on mineral-associated organic matter in soil profiles along an ecosystem gradient.

Mikutta R, Turner S, Schippers A, Gentsch N, Meyer-Stüve S, Condron LM, Peltzer DA, Richardson SJ, Eger A, Hempel G, Kaiser K, Klotzbücher T, Guggenberger G.

Sci Rep. 2019 Jul 16;9(1):10294. doi: 10.1038/s41598-019-46501-4.

13.

Extended Dosing Regimens for Fungal Prophylaxis.

Lehrnbecher T, Bochennek K, Klingebiel T, Gastine S, Hempel G, Groll AH.

Clin Microbiol Rev. 2019 May 15;32(3). pii: e00010-19. doi: 10.1128/CMR.00010-19. Print 2019 Jun 19. Review.

PMID:
31092507
14.

Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure.

Freundt JK, Frommeyer G, Spieker T, Wötzel F, Grotthoff JS, Stypmann J, Hempel G, Schäfers M, Jacobs AH, Eckardt L, Lange PS.

BMC Pharmacol Toxicol. 2019 Mar 6;20(1):16. doi: 10.1186/s40360-019-0294-x.

15.

Medical Education for "Generation Z": Everything online?! - An analysis of Internet-based media use by teachers in medicine.

Vogelsang M, Rockenbauch K, Wrigge H, Heinke W, Hempel G.

GMS J Med Educ. 2018 May 15;35(2):Doc21. doi: 10.3205/zma001168. eCollection 2018. Review.

16.

Treating Anemia in the Preanesthesia Assessment Clinic: Results of a Retrospective Evaluation.

Ellermann I, Bueckmann A, Eveslage M, Buddendick H, Latal T, Niehoff D, Geissler RG, Hempel G, Kerkhoff A, Berdel WE, Roeder N, Van Aken HK, Zarbock A, Steinbicker AU.

Anesth Analg. 2018 Nov;127(5):1202-1210. doi: 10.1213/ANE.0000000000003583.

PMID:
29944518
17.

Clinical consequences of chest tube malposition in trauma resuscitation: single-center experience.

Struck MF, Ewens S, Fakler JKM, Hempel G, Beilicke A, Bernhard M, Stumpp P, Josten C, Stehr SN, Wrigge H, Krämer S.

Eur J Trauma Emerg Surg. 2019 Aug;45(4):687-695. doi: 10.1007/s00068-018-0966-z. Epub 2018 May 31.

PMID:
29855668
18.

Electrical Impedance Tomography for Confirmation of Lung Isolation during One-lung Ventilation.

Hempel G, Schulze G, Wirtz H, Wrigge H.

Anesthesiology. 2018 Sep;129(3):580. doi: 10.1097/ALN.0000000000002189. No abstract available. Erratum in: Anesthesiology. 2018 Aug;129(2):388.

PMID:
29578863
19.

Mechanical complications and outcomes following invasive emergency procedures in severely injured trauma patients.

Struck MF, Fakler JKM, Bernhard M, Busch T, Stumpp P, Hempel G, Beilicke A, Stehr SN, Josten C, Wrigge H.

Sci Rep. 2018 Mar 5;8(1):3976. doi: 10.1038/s41598-018-22457-9.

20.

[Respiratory Failure: Innovations in Diagnostics and Therapy].

Hempel G, Simon P, Salz P, Wrigge H.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2018 Feb;53(2):126-140. doi: 10.1055/s-0043-108216. Epub 2018 Feb 9. Review. German.

PMID:
29426051
21.

Investigation of the age dependency of vancomycin clearance by population pharmacokinetic modeling.

Usman M, Fobker M, Hempel G.

Int J Clin Pharmacol Ther. 2018 Feb;56(2):56-63. doi: 10.5414/CP203033.

PMID:
29319495
22.

Cellular pharmacology studies of anticancer agents: recommendations from the EORTC-PAMM group.

Perego P, Hempel G, Linder S, Bradshaw TD, Larsen AK, Peters GJ, Phillips RM; EORTC PAMM Group.

Cancer Chemother Pharmacol. 2018 Mar;81(3):427-441. doi: 10.1007/s00280-017-3502-7. Epub 2017 Dec 28. Review.

PMID:
29285635
23.

Pharmacokinetics of recombinant asparaginase in children with acute lymphoblastic leukemia.

Völler S, Pichlmeier U, Zens A, Hempel G.

Cancer Chemother Pharmacol. 2018 Feb;81(2):305-314. doi: 10.1007/s00280-017-3492-5. Epub 2017 Dec 5.

PMID:
29204688
24.

An ethnopharmacological survey of medicinal plants traditionally used for cancer treatment in the Ashanti region, Ghana.

Agyare C, Spiegler V, Asase A, Scholz M, Hempel G, Hensel A.

J Ethnopharmacol. 2018 Feb 15;212:137-152. doi: 10.1016/j.jep.2017.10.019. Epub 2017 Oct 21.

PMID:
29066406
25.

Pharmacokinetic Modeling of Voriconazole To Develop an Alternative Dosing Regimen in Children.

Gastine S, Lehrnbecher T, Müller C, Farowski F, Bader P, Ullmann-Moskovits J, Cornely OA, Groll AH, Hempel G.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01194-17. doi: 10.1128/AAC.01194-17. Print 2018 Jan.

26.

Noninvasive ventilation during acute respiratory distress syndrome in patients with cancer-what really matters.

Hempel G, Petroff D, Wrigge H.

J Thorac Dis. 2017 Aug;9(8):2224-2227. doi: 10.21037/jtd.2017.06.131. No abstract available.

27.

A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.

Dallmann A, Ince I, Coboeken K, Eissing T, Hempel G.

Clin Pharmacokinet. 2018 Jun;57(6):749-768. doi: 10.1007/s40262-017-0594-5.

PMID:
28924743
28.

Gestation-Specific Changes in the Anatomy and Physiology of Healthy Pregnant Women: An Extended Repository of Model Parameters for Physiologically Based Pharmacokinetic Modeling in Pregnancy.

Dallmann A, Ince I, Meyer M, Willmann S, Eissing T, Hempel G.

Clin Pharmacokinet. 2017 Nov;56(11):1303-1330. doi: 10.1007/s40262-017-0539-z. Review.

PMID:
28401479
29.

Validation of a dried blood spot method for therapeutic drug monitoring of citalopram, mirtazapine and risperidone and its active metabolite 9-hydroxyrisperidone using HPLC-MS.

Weber J, Oberfeld S, Bonse A, Telger K, Lingg R, Hempel G.

J Pharm Biomed Anal. 2017 Jun 5;140:347-354. doi: 10.1016/j.jpba.2017.02.061. Epub 2017 Mar 27.

PMID:
28395245
30.

Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.

Dallmann A, Ince I, Solodenko J, Meyer M, Willmann S, Eissing T, Hempel G.

Clin Pharmacokinet. 2017 Dec;56(12):1525-1541. doi: 10.1007/s40262-017-0538-0.

PMID:
28391404
31.

Addressing Adherence Using Genotype-Specific PBPK Modeling-Impact of Drug Holidays on Tamoxifen and Endoxifen Plasma Levels.

Dickschen KJ, Willmann S, Hempel G, Block M.

Front Pharmacol. 2017 Mar 14;8:67. doi: 10.3389/fphar.2017.00067. eCollection 2017.

32.

Population Pharmacokinetics to Model the Time-Varying Clearance of the PEGylated Asparaginase Oncaspar® in Children with Acute Lymphoblastic Leukemia.

Würthwein G, Lanvers-Kaminsky C, Hempel G, Gastine S, Möricke A, Schrappe M, Karlsson MO, Boos J.

Eur J Drug Metab Pharmacokinet. 2017 Dec;42(6):955-963. doi: 10.1007/s13318-017-0410-5.

PMID:
28349335
33.

Elimination of digital and analog artefacts from time-domain signals.

Hempel G.

Solid State Nucl Magn Reson. 2017 Apr - May;82-83:29-34. doi: 10.1016/j.ssnmr.2017.01.009. Epub 2017 Feb 3.

PMID:
28187332
34.

Detection of patient-ventilator asynchrony should be improved: and then what?

Wrigge H, Girrbach F, Hempel G.

J Thorac Dis. 2016 Dec;8(12):E1661-E1664. doi: 10.21037/jtd.2016.12.101. No abstract available.

35.

Effect of training and structured medication review on medication appropriateness in nursing home residents and on cooperation between health care professionals: the InTherAKT study protocol.

Mahlknecht A, Nestler N, Bauer U, Schüßler N, Schuler J, Scharer S, Becker R, Waltering I, Hempel G, Schwalbe O, Flamm M, Osterbrink J.

BMC Geriatr. 2017 Jan 18;17(1):24. doi: 10.1186/s12877-017-0418-3.

36.

[Traumatology in the elderly : Multimodal prevention of delirium and use of augmentation techniques].

Wähnert D, Roos A, Glasbrenner J, Ilting-Reuke K, Ohrmann P, Hempel G, Duning T, Roeder N, Raschke MJ.

Chirurg. 2017 Feb;88(2):95-104. doi: 10.1007/s00104-016-0339-2. Review. German.

PMID:
28058496
37.

Development of a Physiologically Based Pharmacokinetic Modelling Approach to Predict the Pharmacokinetics of Vancomycin in Critically Ill Septic Patients.

Radke C, Horn D, Lanckohr C, Ellger B, Meyer M, Eissing T, Hempel G.

Clin Pharmacokinet. 2017 Jul;56(7):759-779. doi: 10.1007/s40262-016-0475-3.

PMID:
28039606
38.

Population pharmacokinetics of meropenem in elderly patients: dosing simulations based on renal function.

Usman M, Frey OR, Hempel G.

Eur J Clin Pharmacol. 2017 Mar;73(3):333-342. doi: 10.1007/s00228-016-2172-4. Epub 2016 Dec 13.

PMID:
27966034
39.

[Information content of medication schedules prior to the implementation of the federal standard medication plan].

Waltering I, Schwalbe O, Hempel G.

Z Evid Fortbild Qual Gesundhwes. 2016 Oct;115-116:24-32. doi: 10.1016/j.zefq.2016.06.004. German.

PMID:
27837957
40.

Pharmacokinetic and pharmacodynamic study of doxorubicin in children with cancer: results of a "European Pediatric Oncology Off-patents Medicines Consortium" trial.

Krischke M, Hempel G, Völler S, André N, D'Incalci M, Bisogno G, Köpcke W, Borowski M, Herold R, Boddy AV, Boos J.

Cancer Chemother Pharmacol. 2016 Dec;78(6):1175-1184. doi: 10.1007/s00280-016-3174-8. Epub 2016 Oct 21.

41.

Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.

Bartelink IH, Lalmohamed A, van Reij EM, Dvorak CC, Savic RM, Zwaveling J, Bredius RG, Egberts AC, Bierings M, Kletzel M, Shaw PJ, Nath CE, Hempel G, Ansari M, Krajinovic M, Théorêt Y, Duval M, Keizer RJ, Bittencourt H, Hassan M, Güngör T, Wynn RF, Veys P, Cuvelier GD, Marktel S, Chiesa R, Cowan MJ, Slatter MA, Stricherz MK, Jennissen C, Long-Boyle JR, Boelens JJ.

Lancet Haematol. 2016 Nov;3(11):e526-e536. doi: 10.1016/S2352-3026(16)30114-4. Epub 2016 Oct 13.

42.

[Perioperative adverse respiratory events in overweight and obese children].

Ulrici J, Hempel G, Sasse M, Vollrath J, Höhne C.

Anaesthesist. 2016 Dec;65(12):911-916. Epub 2016 Oct 10. German.

PMID:
27726001
43.

The effect of cyclophosphamide on the immune system: implications for clinical cancer therapy.

Ahlmann M, Hempel G.

Cancer Chemother Pharmacol. 2016 Oct;78(4):661-71. doi: 10.1007/s00280-016-3152-1. Epub 2016 Sep 19. Review.

PMID:
27646791
44.

Towards a Model-Based Dose Recommendation for Doxorubicin in Children.

Völler S, Hempel G, Würthwein G, Boddy AV, Krischke M, André N, D'Incalci M, Bisogno G, Boos J.

Clin Pharmacokinet. 2017 Mar;56(3):215-223. doi: 10.1007/s40262-016-0451-y.

45.

Pharmacokinetic characteristics and microbiologic appropriateness of cefazolin for perioperative antibiotic prophylaxis in elective cardiac surgery.

Lanckohr C, Horn D, Voeller S, Hempel G, Fobker M, Welp H, Koeck R, Ellger B.

J Thorac Cardiovasc Surg. 2016 Aug;152(2):603-10. doi: 10.1016/j.jtcvs.2016.04.024. Epub 2016 Apr 11.

46.
47.

Asymmetrical flow field-flow fractionation for the analysis of PEG-asparaginase.

John C, Herz T, Boos J, Langer K, Hempel G.

Talanta. 2016;146:335-9. doi: 10.1016/j.talanta.2015.08.028. Epub 2015 Aug 29.

PMID:
26695272
48.

Impact of medication therapy management in patients with Parkinson's disease.

Henrichsmann M, Hempel G.

Int J Clin Pharm. 2016 Feb;38(1):54-60. doi: 10.1007/s11096-015-0206-0. Epub 2015 Nov 21.

PMID:
26590989
49.

Basic principles of static proton low-resolution spin diffusion NMR in nanophase-separated materials with mobility contrast.

Schäler K, Roos M, Micke P, Golitsyn Y, Seidlitz A, Thurn-Albrecht T, Schneider H, Hempel G, Saalwächter K.

Solid State Nucl Magn Reson. 2015 Nov;72:50-63. doi: 10.1016/j.ssnmr.2015.09.001. Epub 2015 Sep 3.

PMID:
26404771
50.

Moderate MAS enhances local (1)H spin exchange and spin diffusion.

Roos M, Micke P, Saalwächter K, Hempel G.

J Magn Reson. 2015 Nov;260:28-37. doi: 10.1016/j.jmr.2015.08.016. Epub 2015 Sep 5.

PMID:
26397218

Supplemental Content

Loading ...
Support Center