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Items: 1 to 50 of 86

1.

Stereoselective nucleophilic addition reactions to cyclic N-acyliminium ions using the indirect cation pool method: Elucidation of stereoselectivity by spectroscopic conformational analysis and DFT calculations.

Mitsudo K, Yamamoto J, Akagi T, Yamashita A, Haisa M, Yoshioka K, Mandai H, Ueoka K, Hempel C, Yoshida JI, Suga S.

Beilstein J Org Chem. 2018 May 24;14:1192-1202. doi: 10.3762/bjoc.14.100. eCollection 2018.

2.

Luminescence from Lanthanide(III) Ions Bound to the Glycocalyx of Chinese Hamster Ovary Cells.

Arppe-Tabbara R, Carro-Temboury MR, Hempel C, Vosch T, Sørensen TJ.

Chemistry. 2018 Jun 25. doi: 10.1002/chem.201802799. [Epub ahead of print]

PMID:
29939467
3.

Detection of Glycan Shedding in the Blood: New Class of Multiple Sclerosis Biomarkers?

DellaValle B, Manresa-Arraut A, Hasseldam H, Stensballe A, Rungby J, Larsen A, Hempel C.

Front Immunol. 2018 Jun 4;9:1254. doi: 10.3389/fimmu.2018.01254. eCollection 2018.

4.

G Protein Preassembly Rescues Efficacy of W6.48 Toggle Mutations in Neuropeptide Y2 Receptor.

Kaiser A, Hempel C, Wanka L, Schubert M, Hamm HE, Beck-Sickinger AG.

Mol Pharmacol. 2018 Apr;93(4):387-401. doi: 10.1124/mol.117.110544. Epub 2018 Feb 7.

PMID:
29436493
5.

Increased Plasmodium chabaudi malaria mortality in mice with nutritional iron deficiency can be reduced by short-term adjunctive iron supplementation.

Castberg FC, Maretty L, Staalsoe T, Hempel C, Clasen-Linde E, Hviid L, Kurtzhals JAL.

Malar J. 2018 Jan 16;17(1):34. doi: 10.1186/s12936-018-2186-8.

6.

Creating infinite contrast in fluorescence microscopy by using lanthanide centered emission.

Carro-Temboury MR, Arppe R, Hempel C, Vosch T, Just Sørensen T.

PLoS One. 2017 Dec 13;12(12):e0189529. doi: 10.1371/journal.pone.0189529. eCollection 2017.

7.

Investigating dye performance and crosstalk in fluorescence enabled bioimaging using a model system.

Arppe R, Carro-Temboury MR, Hempel C, Vosch T, Just Sørensen T.

PLoS One. 2017 Nov 27;12(11):e0188359. doi: 10.1371/journal.pone.0188359. eCollection 2017.

8.

Direct Observation of Dynamical Quantum Phase Transitions in an Interacting Many-Body System.

Jurcevic P, Shen H, Hauke P, Maier C, Brydges T, Hempel C, Lanyon BP, Heyl M, Blatt R, Roos CF.

Phys Rev Lett. 2017 Aug 25;119(8):080501. doi: 10.1103/PhysRevLett.119.080501. Epub 2017 Aug 21.

PMID:
28952773
9.

Targeting neuronal function for CNS drug discovery.

Hempel CM, Werley CA, Dempsey GT, Gerber DJ.

Drug Discov Today Technol. 2017 Mar;23:17-25. doi: 10.1016/j.ddtec.2017.03.005. Epub 2017 May 6. Review.

PMID:
28647082
10.

Tight junction strand formation by claudin-10 isoforms and claudin-10a/-10b chimeras.

Milatz S, Piontek J, Hempel C, Meoli L, Grohe C, Fromm A, Lee IM, El-Athman R, Günzel D.

Ann N Y Acad Sci. 2017 Oct;1405(1):102-115. doi: 10.1111/nyas.13393. Epub 2017 Jun 20.

PMID:
28633196
11.

Cryo scanning electron microscopy of Plasmodium falciparum-infected erythrocytes.

Hempel C.

APMIS. 2017 Jul;125(7):650-654. doi: 10.1111/apm.12699. Epub 2017 May 11.

PMID:
28493454
12.

Binding of Plasmodium falciparum to CD36 can be shielded by the glycocalyx.

Hempel C, Wang CW, Kurtzhals JAL, Staalsø T.

Malar J. 2017 May 10;16(1):193. doi: 10.1186/s12936-017-1844-6.

13.

Polar and charged extracellular residues conserved among barrier-forming claudins contribute to tight junction strand formation.

Piontek A, Rossa J, Protze J, Wolburg H, Hempel C, Günzel D, Krause G, Piontek J.

Ann N Y Acad Sci. 2017 Jun;1397(1):143-156. doi: 10.1111/nyas.13341. Epub 2017 Apr 17.

PMID:
28415153
14.

Towards Precision in HF Pharmacotherapy.

Norgard NB, Hempel C.

Curr Heart Fail Rep. 2017 Feb;14(1):1-6. doi: 10.1007/s11897-017-0314-3. Review.

PMID:
28190189
15.

Discovery of novel dual inhibitors of receptor tyrosine kinases EGFR and IGF-1R.

Hempel C, Totzke F, Schächtele C, Najjar A, Sippl W, Ritter C, Hilgeroth A.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):271-276. doi: 10.1080/14756366.2016.1247062.

16.

Upregulation of μ3A Drives Homeostatic Plasticity by Rerouting AMPAR into the Recycling Endosomal Pathway.

Steinmetz CC, Tatavarty V, Sugino K, Shima Y, Joseph A, Lin H, Rutlin M, Lambo M, Hempel CM, Okaty BW, Paradis S, Nelson SB, Turrigiano GG.

Cell Rep. 2016 Sep 6;16(10):2711-2722. doi: 10.1016/j.celrep.2016.08.009. Epub 2016 Aug 25.

17.

Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria.

DellaValle B, Hempel C, Staalsoe T, Johansen FF, Kurtzhals JA.

Malar J. 2016 Aug 24;15(1):427. doi: 10.1186/s12936-016-1486-0. Erratum in: Malar J. 2016;15(1):495.

18.

Efficacy and Safety of High-Dose Subcutaneous Unfractionated Heparin Prophylaxis for the Prevention of Venous Thromboembolism in Obese Hospitalized Patients.

Beall J, Woodruff A, Hempel C, Wovkulich M, Zammit K.

Hosp Pharm. 2016 May;51(5):376-81. doi: 10.1310/hpj5105-376.

19.

Swelling behavior of bisensitive interpenetrating polymer networks for microfluidic applications.

Krause AT, Zschoche S, Rohn M, Hempel C, Richter A, Appelhans D, Voit B.

Soft Matter. 2016 Jul 7;12(25):5529-36. doi: 10.1039/c6sm00720a. Epub 2016 May 13.

PMID:
27174740
20.

Endothelial Glycocalyx: Shedding Light on Malaria Pathogenesis.

Hempel C, Pasini EM, Kurtzhals JAL.

Trends Mol Med. 2016 Jun;22(6):453-457. doi: 10.1016/j.molmed.2016.04.004. Epub 2016 May 5. Review.

PMID:
27161599
21.

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.

Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E.

Sci Transl Med. 2016 Apr 6;8(333):333ra50. doi: 10.1126/scitranslmed.aad6100.

22.

A Mammalian enhancer trap resource for discovering and manipulating neuronal cell types.

Shima Y, Sugino K, Hempel CM, Shima M, Taneja P, Bullis JB, Mehta S, Lois C, Nelson SB.

Elife. 2016 Mar 21;5:e13503. doi: 10.7554/eLife.13503.

23.

Discharge Diuretic Dose and 30-Day Readmission Rate in Acute Decompensated Heart Failure.

Woodruff AE, Kelley AM, Hempel CA, Loeffler WJ, Echtenkamp CA, Hassan AK.

Ann Pharmacother. 2016 Jun;50(6):437-45. doi: 10.1177/1060028016637385. Epub 2016 Mar 8.

PMID:
26956954
24.

Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed.

Subramani R, Quadt K, Jeppesen AE, Hempel C, Petersen JE, Hassenkam T, Hviid L, Barfod L.

MBio. 2015 Oct 6;6(5):e01456-15. doi: 10.1128/mBio.01456-15.

25.

How important is local food to organic-minded consumers?

Hempel C, Hamm U.

Appetite. 2016 Jan 1;96:309-318. doi: 10.1016/j.appet.2015.09.036. Epub 2015 Oct 22.

PMID:
26432955
26.

Spectroscopy of Interacting Quasiparticles in Trapped Ions.

Jurcevic P, Hauke P, Maier C, Hempel C, Lanyon BP, Blatt R, Roos CF.

Phys Rev Lett. 2015 Sep 4;115(10):100501. Epub 2015 Sep 1.

PMID:
26382670
27.

Polymorphisms in the Haem Oxygenase-1 promoter are not associated with severity of Plasmodium falciparum malaria in Ghanaian children.

Hansson HH, Maretty L, Balle C, Goka BQ, Luzon E, Nkrumah FN, Schousboe ML, Rodrigues OP, Bygbjerg IC, Kurtzhals JA, Alifrangis M, Hempel C.

Malar J. 2015 Apr 11;14:153. doi: 10.1186/s12936-015-0668-5.

28.

An automated method for determining the cytoadhesion of Plasmodium falciparum-infected erythrocytes to immobilized cells.

Hempel C, Boisen IM, Efunshile A, Kurtzhals JA, Staalsø T.

Malar J. 2015 Mar 14;14:112. doi: 10.1186/s12936-015-0632-4.

29.

GLP-1 improves neuropathology after murine cold lesion brain trauma.

DellaValle B, Hempel C, Johansen FF, Kurtzhals JA.

Ann Clin Transl Neurol. 2014 Sep;1(9):721-32. doi: 10.1002/acn3.99. Epub 2014 Sep 30. Erratum in: Ann Clin Transl Neurol. 2016 Aug;3(8):664.

30.

Plasmodium falciparum avoids change in erythrocytic surface expression of phagocytosis markers during inhibition of nitric oxide synthase activity.

Hempel C, Kohnke H, Maretty L, Jensen PØ, Staalsø T, Kurtzhals JA.

Mol Biochem Parasitol. 2014 Nov;198(1):29-36. doi: 10.1016/j.molbiopara.2014.11.003. Epub 2014 Nov 29.

PMID:
25454716
31.

Cell-type-specific repression by methyl-CpG-binding protein 2 is biased toward long genes.

Sugino K, Hempel CM, Okaty BW, Arnson HA, Kato S, Dani VS, Nelson SB.

J Neurosci. 2014 Sep 17;34(38):12877-83. doi: 10.1523/JNEUROSCI.2674-14.2014.

32.

Experimental generation of quantum discord via noisy processes.

Lanyon BP, Jurcevic P, Hempel C, Gessner M, Vedral V, Blatt R, Roos CF.

Phys Rev Lett. 2013 Sep 6;111(10):100504. Epub 2013 Sep 5.

PMID:
25166643
33.

Quasiparticle engineering and entanglement propagation in a quantum many-body system.

Jurcevic P, Lanyon BP, Hauke P, Hempel C, Zoller P, Blatt R, Roos CF.

Nature. 2014 Jul 10;511(7508):202-5. doi: 10.1038/nature13461.

PMID:
25008526
34.

Systemic and Cerebral Vascular Endothelial Growth Factor Levels Increase in Murine Cerebral Malaria along with Increased Calpain and Caspase Activity and Can be Reduced by Erythropoietin Treatment.

Hempel C, Hoyer N, Kildemoes A, Jendresen CB, Kurtzhals JA.

Front Immunol. 2014 Jun 19;5:291. doi: 10.3389/fimmu.2014.00291. eCollection 2014.

35.

Effects of the vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor SU5416 on in vitro cultures of Plasmodium falciparum.

Hempel C, Hoyer N, Staalsø T, Kurtzhals JA.

Malar J. 2014 May 28;13:201. doi: 10.1186/1475-2875-13-201.

36.

Endothelial glycocalyx on brain endothelial cells is lost in experimental cerebral malaria.

Hempel C, Hyttel P, Kurtzhals JA.

J Cereb Blood Flow Metab. 2014 Jul;34(7):1107-10. doi: 10.1038/jcbfm.2014.79. Epub 2014 Apr 23.

37.

Experimental violation of multipartite Bell inequalities with trapped ions.

Lanyon BP, Zwerger M, Jurcevic P, Hempel C, Dür W, Briegel HJ, Blatt R, Roos CF.

Phys Rev Lett. 2014 Mar 14;112(10):100403. Epub 2014 Mar 13.

PMID:
24679272
38.

Nitric oxide production by polymorphonuclear leucocytes in infected cystic fibrosis sputum consumes oxygen.

Kolpen M, Bjarnsholt T, Moser C, Hansen CR, Rickelt LF, Kühl M, Hempel C, Pressler T, Høiby N, Jensen PØ.

Clin Exp Immunol. 2014 Jul;177(1):310-9. doi: 10.1111/cei.12318.

39.

Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms.

Jensen PØ, Briales A, Brochmann RP, Wang H, Kragh KN, Kolpen M, Hempel C, Bjarnsholt T, Høiby N, Ciofu O.

Pathog Dis. 2014 Apr;70(3):440-3. doi: 10.1111/2049-632X.12120. Epub 2014 Feb 10.

PMID:
24376174
40.

Bactericidal effect of colistin on planktonic Pseudomonas aeruginosa is independent of hydroxyl radical formation.

Brochmann RP, Toft A, Ciofu O, Briales A, Kolpen M, Hempel C, Bjarnsholt T, Høiby N, Jensen PØ.

Int J Antimicrob Agents. 2014 Feb;43(2):140-7. doi: 10.1016/j.ijantimicag.2013.10.015. Epub 2013 Nov 15.

PMID:
24315789
41.

Measurement-based quantum computation with trapped ions.

Lanyon BP, Jurcevic P, Zwerger M, Hempel C, Martinez EA, Dür W, Briegel HJ, Blatt R, Roos CF.

Phys Rev Lett. 2013 Nov 22;111(21):210501. Epub 2013 Nov 19.

PMID:
24313469
42.

Geno- and phenotypic characterization of human cytomegalovirus mutants selected in vitro after letermovir (AIC246) exposure.

Goldner T, Hempel C, Ruebsamen-Schaeff H, Zimmermann H, Lischka P.

Antimicrob Agents Chemother. 2014;58(1):610-3. doi: 10.1128/AAC.01794-13. Epub 2013 Nov 4.

43.

The phenothiazine-class antipsychotic drugs prochlorperazine and trifluoperazine are potent allosteric modulators of the human P2X7 receptor.

Hempel C, Nörenberg W, Sobottka H, Urban N, Nicke A, Fischer W, Schaefer M.

Neuropharmacology. 2013 Dec;75:365-79. doi: 10.1016/j.neuropharm.2013.07.027. Epub 2013 Aug 14.

PMID:
23954492
44.

Working memory impairment in calcineurin knock-out mice is associated with alterations in synaptic vesicle cycling and disruption of high-frequency synaptic and network activity in prefrontal cortex.

Cottrell JR, Levenson JM, Kim SH, Gibson HE, Richardson KA, Sivula M, Li B, Ashford CJ, Heindl KA, Babcock RJ, Rose DM, Hempel CM, Wiig KA, Laeng P, Levin ME, Ryan TA, Gerber DJ.

J Neurosci. 2013 Jul 3;33(27):10938-49. doi: 10.1523/JNEUROSCI.5362-12.2013.

45.

Investigation of hydrogen sulfide gas as a treatment against P. falciparum, murine cerebral malaria, and the importance of thiolation state in the development of cerebral malaria.

DellaValle B, Staalsoe T, Kurtzhals JA, Hempel C.

PLoS One. 2013;8(3):e59271. doi: 10.1371/journal.pone.0059271. Epub 2013 Mar 26.

46.

Novel structurally varied N-alkyl 1,4-dihydropyridines as ABCB1 inhibitors: structure-activity relationships, biological activity and first bioanalytical evaluation.

Hilgeroth A, Baumert C, Coburger C, Seifert M, Krawczyk S, Hempel C, Neubauer F, Krug M, Molnár J, Lage H.

Med Chem. 2013 Jun 1;9(4):487-93.

PMID:
23167942
47.

MicroRNA-146a-mediated downregulation of IRAK1 protects mouse and human small intestine against ischemia/reperfusion injury.

Chassin C, Hempel C, Stockinger S, Dupont A, Kübler JF, Wedemeyer J, Vandewalle A, Hornef MW.

EMBO Mol Med. 2012 Dec;4(12):1308-19. doi: 10.1002/emmm.201201298. Epub 2012 Nov 9.

48.

A hypervalent iodine-mediated spirocyclization of 2-(4-hydroxybenzamido)acrylates--unexpected formation of δ-spirolactones.

Hempel C, Weckenmann NM, Maichle-Moessmer C, Nachtsheim BJ.

Org Biomol Chem. 2012 Dec 21;10(47):9325-9. doi: 10.1039/c2ob26815a. Epub 2012 Nov 1.

PMID:
23117367
49.

Getting under the skin of adverse drug reactions.

Hempel C, Martin C.

Orthopedics. 2012 Oct;35(10):872-6. doi: 10.3928/01477447-20120919-07. Review.

PMID:
23027476
50.

Broad consent in biobanking.

Hempel C, Lomax G, Peckman S.

Nat Biotechnol. 2012 Sep;30(9):826. doi: 10.1038/nbt.2349. No abstract available.

PMID:
22965048

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