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Items: 1 to 50 of 269

1.

Conserved Pyridoxal 5'-Phosphate-Binding Protein YggS Impacts Amino Acid Metabolism through Pyridoxine 5'-Phosphate in Escherichia coli.

Ito T, Yamamoto K, Hori R, Yamauchi A, Downs DM, Hemmi H, Yoshimura T.

Appl Environ Microbiol. 2019 May 16;85(11). pii: e00430-19. doi: 10.1128/AEM.00430-19. Print 2019 Jun 1.

PMID:
30902856
2.

Conversion of Mevalonate 3-Kinase into 5-Phosphomevalonate 3-Kinase by Single Amino Acid Mutations.

Motoyama K, Sobue F, Kawaide H, Yoshimura T, Hemmi H.

Appl Environ Microbiol. 2019 Apr 18;85(9). pii: e00256-19. doi: 10.1128/AEM.00256-19. Print 2019 May 1.

PMID:
30824437
3.

Hyperglycemia Is Associated with Psoriatic Inflammation in Both Humans and Mice.

Ikumi K, Odanaka M, Shime H, Imai M, Osaga S, Taguchi O, Nishida E, Hemmi H, Kaisho T, Morita A, Yamazaki S.

J Invest Dermatol. 2019 Jun;139(6):1329-1338.e7. doi: 10.1016/j.jid.2019.01.029. Epub 2019 Feb 15.

PMID:
30776434
4.

Identification of a novel CCDC22 mutation in a patient with severe Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis and aggressive natural killer cell leukemia.

Yamashita Y, Nishikawa A, Iwahashi Y, Fujimoto M, Sasaki I, Mishima H, Kinoshita A, Hemmi H, Kanazawa N, Ohshima K, Imadome KI, Murata SI, Yoshiura KI, Kaisho T, Sonoki T, Tamura S.

Int J Hematol. 2019 Jun;109(6):744-750. doi: 10.1007/s12185-019-02595-0. Epub 2019 Jan 31.

PMID:
30706328
5.

Programmed cell death ligand 1 disruption by clustered regularly interspaced short palindromic repeats/Cas9-genome editing promotes antitumor immunity and suppresses ovarian cancer progression.

Yahata T, Mizoguchi M, Kimura A, Orimo T, Toujima S, Kuninaka Y, Nosaka M, Ishida Y, Sasaki I, Fukuda-Ohta Y, Hemmi H, Iwahashi N, Noguchi T, Kaisho T, Kondo T, Ino K.

Cancer Sci. 2019 Apr;110(4):1279-1292. doi: 10.1111/cas.13958. Epub 2019 Feb 27.

6.

Cholera toxin B induces interleukine-1β production from resident peritoneal macrophages through pyrin as well as NLRP3 inflammasome.

Orimo T, Sasaki I, Hemmi H, Ozasa T, Fukuda-Ohta Y, Ohta T, Morinaka M, Kitauchi M, Yamaguchi T, Sato Y, Tanaka T, Hoshino K, Katayama KI, Fukuda S, Miyake K, Yamamoto M, Satoh T, Furukawa K, Kuroda E, Ishii KJ, Takeda K, Kaisho T.

Int Immunol. 2019 Jan 25. doi: 10.1093/intimm/dxz004. [Epub ahead of print]

PMID:
30689886
7.

Isolation and structure determination of a new lasso peptide specialicin based on genome mining.

Kaweewan I, Hemmi H, Komaki H, Harada S, Kodani S.

Bioorg Med Chem. 2018 Dec 15;26(23-24):6050-6055. doi: 10.1016/j.bmc.2018.11.007. Epub 2018 Nov 9.

PMID:
30448257
8.

[In Vivo Antigen Delivery to Dendritic Cells-A Novel Peptide Vaccine for Cancer Therapy].

Mizumoto Y, Katsuda M, Miyazawa M, Kitahata Y, Miyamoto A, Nakamori M, Ojima T, Matsuda K, Hemmi H, Tamada K, Kaisho T, Yamaue H.

Gan To Kagaku Ryoho. 2018 Oct;45(10):1469-1471. Japanese.

PMID:
30382048
9.

Isolation and structure determination of a new cytotoxic peptide, curacozole, from Streptomyces curacoi based on genome mining.

Kaweewan I, Komaki H, Hemmi H, Hoshino K, Hosaka T, Isokawa G, Oyoshi T, Kodani S.

J Antibiot (Tokyo). 2019 Jan;72(1):1-7. doi: 10.1038/s41429-018-0105-4. Epub 2018 Oct 11.

PMID:
30310179
10.

Structures and Catalytic Activities of Complexes between Heme and All Parallel-Stranded Monomeric G-Quadruplex DNAs.

Yamamoto Y, Araki H, Shinomiya R, Hayasaka K, Nakayama Y, Ochi K, Shibata T, Momotake A, Ohyama T, Hagihara M, Hemmi H.

Biochemistry. 2018 Oct 16;57(41):5938-5948. doi: 10.1021/acs.biochem.8b00792. Epub 2018 Oct 4.

PMID:
30234971
11.

Modified mevalonate pathway of the archaeon Aeropyrum pernix proceeds via trans-anhydromevalonate 5-phosphate.

Hayakawa H, Motoyama K, Sobue F, Ito T, Kawaide H, Yoshimura T, Hemmi H.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10034-10039. doi: 10.1073/pnas.1809154115. Epub 2018 Sep 17.

12.

Heterologous production of a new lasso peptide brevunsin in Sphingomonas subterranea.

Kodani S, Hemmi H, Miyake Y, Kaweewan I, Nakagawa H.

J Ind Microbiol Biotechnol. 2018 Nov;45(11):983-992. doi: 10.1007/s10295-018-2077-6. Epub 2018 Sep 6.

PMID:
30191430
13.

Streptopeptolin, a Cyanopeptolin-Type Peptide from Streptomyces olivochromogenes.

Kodani S, Komaki H, Hemmi H, Miyake Y, Kaweewan I, Dohra H.

ACS Omega. 2018 Jul 31;3(7):8104-8110. doi: 10.1021/acsomega.8b01042. Epub 2018 Jul 19.

14.

D-Serine Metabolism and Its Importance in Development of Dictyostelium discoideum.

Ito T, Hamauchi N, Hagi T, Morohashi N, Hemmi H, Sato YG, Saito T, Yoshimura T.

Front Microbiol. 2018 Apr 24;9:784. doi: 10.3389/fmicb.2018.00784. eCollection 2018.

15.

Biosynthetic machinery for C25,C25-diether archaeal lipids from the hyperthermophilic archaeon Aeropyrum pernix.

Yoshida R, Yoshimura T, Hemmi H.

Biochem Biophys Res Commun. 2018 Feb 26;497(1):87-92. doi: 10.1016/j.bbrc.2018.02.028. Epub 2018 Feb 7.

PMID:
29427665
16.

Production of Ophthalmic Acid Using Engineered Escherichia coli.

Ito T, Tokoro M, Hori R, Hemmi H, Yoshimura T.

Appl Environ Microbiol. 2018 Mar 19;84(7). pii: e02806-17. doi: 10.1128/AEM.02806-17. Print 2018 Apr 1.

17.

Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration.

Ishida Y, Kimura A, Nosaka M, Kuninaka Y, Hemmi H, Sasaki I, Kaisho T, Mukaida N, Kondo T.

Sci Rep. 2017 Dec 4;7(1):16833. doi: 10.1038/s41598-017-17007-8.

18.

Utilization of an intermediate of the methylerythritol phosphate pathway, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate, as the prenyl donor substrate for various prenyltransferases.

Hayashi Y, Ito T, Yoshimura T, Hemmi H.

Biosci Biotechnol Biochem. 2018 Jun;82(6):993-1002. doi: 10.1080/09168451.2017.1398064. Epub 2017 Dec 1.

PMID:
29191109
19.

Ultraviolet B-Induced Maturation of CD11b-Type Langerin- Dendritic Cells Controls the Expansion of Foxp3+ Regulatory T Cells in the Skin.

Yamazaki S, Odanaka M, Nishioka A, Kasuya S, Shime H, Hemmi H, Imai M, Riethmacher D, Kaisho T, Ohkura N, Sakaguchi S, Morita A.

J Immunol. 2018 Jan 1;200(1):119-129. doi: 10.4049/jimmunol.1701056. Epub 2017 Nov 20.

20.

Occurrence of the (2R,3S)-Isomer of 2-Amino-3,4-dihydroxybutanoic Acid in the Mushroom Hypsizygus marmoreus.

Ito T, Yu Z, Yoshino I, Hirozawa Y, Yamamoto K, Shinoda K, Watanabe A, Hemmi H, Asada Y, Yoshimura T.

J Agric Food Chem. 2017 Aug 2;65(30):6131-6139. doi: 10.1021/acs.jafc.7b01893. Epub 2017 Jul 24.

PMID:
28686838
21.

Identification of enzymes involved in the mevalonate pathway of Flavobacterium johnsoniae.

Hayakawa H, Sobue F, Motoyama K, Yoshimura T, Hemmi H.

Biochem Biophys Res Commun. 2017 Jun 3;487(3):702-708. doi: 10.1016/j.bbrc.2017.04.120. Epub 2017 Apr 23.

PMID:
28442346
22.

A Single Amino Acid Mutation Converts (R)-5-Diphosphomevalonate Decarboxylase into a Kinase.

Motoyama K, Unno H, Hattori A, Takaoka T, Ishikita H, Kawaide H, Yoshimura T, Hemmi H.

J Biol Chem. 2017 Feb 10;292(6):2457-2469. doi: 10.1074/jbc.M116.752535. Epub 2016 Dec 21.

23.

Esophageal Endoscopic Submucosal Dissection Assisted by an Overtube with a Traction Forceps: An Animal Study.

Ohata K, Fu K, Sakai E, Nonaka K, Tashima T, Minato Y, Ohno A, Ito T, Tsuji Y, Chiba H, Yamawaki M, Hemmi H, Nakaya T, Fukushima J, Matsuhashi N.

Gastroenterol Res Pract. 2016;2016:3186168. doi: 10.1155/2016/3186168. Epub 2016 Jul 27.

24.

Ophthalmic acid accumulation in an Escherichia coli mutant lacking the conserved pyridoxal 5'-phosphate-binding protein YggS.

Ito T, Yamauchi A, Hemmi H, Yoshimura T.

J Biosci Bioeng. 2016 Dec;122(6):689-693. doi: 10.1016/j.jbiosc.2016.06.010. Epub 2016 Jul 12.

PMID:
27426274
25.

Isolation and structure determination of a new lantibiotic cinnamycin B from Actinomadura atramentaria based on genome mining.

Kodani S, Komaki H, Ishimura S, Hemmi H, Ohnishi-Kameyama M.

J Ind Microbiol Biotechnol. 2016 Aug;43(8):1159-65. doi: 10.1007/s10295-016-1788-9. Epub 2016 Jun 2.

PMID:
27255974
26.

Isolation and structural determination of a new antibacterial compound demethyl-L-681,217 from Streptomyces cattleya.

Sugai S, Komaki H, Hemmi H, Kodani S.

J Antibiot (Tokyo). 2016 Nov;69(11):839-842. doi: 10.1038/ja.2016.53. Epub 2016 May 25. No abstract available.

PMID:
27220410
27.

NMR analysis on the sialic acid-binding mechanism of an R-type lectin mutant by natural evolution-mimicry.

Hemmi H, Kuno A, Unno S, Hirabayashi J.

FEBS Lett. 2016 Jun;590(12):1720-8. doi: 10.1002/1873-3468.12212. Epub 2016 May 26.

28.

In Vivo Ablation of a Dendritic Cell Subset Expressing the Chemokine Receptor XCR1.

Hemmi H, Hoshino K, Kaisho T.

Methods Mol Biol. 2016;1423:247-53. doi: 10.1007/978-1-4939-3606-9_17.

PMID:
27142021
29.

A cis-prenyltransferase from Methanosarcina acetivorans catalyzes both head-to-tail and nonhead-to-tail prenyl condensation.

Ogawa T, Emi K, Koga K, Yoshimura T, Hemmi H.

FEBS J. 2016 Jun;283(12):2369-83. doi: 10.1111/febs.13749. Epub 2016 May 17.

30.

Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis.

Ohta T, Sugiyama M, Hemmi H, Yamazaki C, Okura S, Sasaki I, Fukuda Y, Orimo T, Ishii KJ, Hoshino K, Ginhoux F, Kaisho T.

Sci Rep. 2016 Mar 23;6:23505. doi: 10.1038/srep23505.

31.

Imaging of the cross-presenting dendritic cell subsets in the skin-draining lymph node.

Kitano M, Yamazaki C, Takumi A, Ikeno T, Hemmi H, Takahashi N, Shimizu K, Fraser SE, Hoshino K, Kaisho T, Okada T.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1044-9. doi: 10.1073/pnas.1513607113. Epub 2016 Jan 11.

32.

Microsatellite Alterations With Allelic Loss at 9p24.2 Signify Less-Aggressive Colorectal Cancer Metastasis.

Koi M, Garcia M, Choi C, Kim HR, Koike J, Hemmi H, Nagasaka T, Okugawa Y, Toiyama Y, Kitajima T, Imaoka H, Kusunoki M, Chen YH, Mukherjee B, Boland CR, Carethers JM.

Gastroenterology. 2016 Apr;150(4):944-55. doi: 10.1053/j.gastro.2015.12.032. Epub 2016 Jan 2.

33.

A phytoene desaturase homolog gene from the methanogenic archaeon Methanosarcina acetivorans is responsible for hydroxyarchaeol biosynthesis.

Mori T, Isobe K, Ogawa T, Yoshimura T, Hemmi H.

Biochem Biophys Res Commun. 2015 Oct 16;466(2):186-91. doi: 10.1016/j.bbrc.2015.09.001. Epub 2015 Sep 7.

PMID:
26361140
34.

In Vivo Formation of the Protein Disulfide Bond That Enhances the Thermostability of Diphosphomevalonate Decarboxylase, an Intracellular Enzyme from the Hyperthermophilic Archaeon Sulfolobus solfataricus.

Hattori A, Unno H, Goda S, Motoyama K, Yoshimura T, Hemmi H.

J Bacteriol. 2015 Nov;197(21):3463-71. doi: 10.1128/JB.00352-15. Epub 2015 Aug 24.

35.

Robust Anti-viral Immunity Requires Multiple Distinct T Cell-Dendritic Cell Interactions.

Eickhoff S, Brewitz A, Gerner MY, Klauschen F, Komander K, Hemmi H, Garbi N, Kaisho T, Germain RN, Kastenmüller W.

Cell. 2015 Sep 10;162(6):1322-37. doi: 10.1016/j.cell.2015.08.004. Epub 2015 Aug 18.

36.

A new member of MocR/GabR-type PLP-binding regulator of D-alanyl-D-alanine ligase in Brevibacillus brevis.

Takenaka T, Ito T, Miyahara I, Hemmi H, Yoshimura T.

FEBS J. 2015 Nov;282(21):4201-17. doi: 10.1111/febs.13415. Epub 2015 Sep 8.

37.

A highly selective biosynthetic pathway to non-natural C50 carotenoids assembled from moderately selective enzymes.

Furubayashi M, Ikezumi M, Takaichi S, Maoka T, Hemmi H, Ogawa T, Saito K, Tobias AV, Umeno D.

Nat Commun. 2015 Jul 14;6:7534. doi: 10.1038/ncomms8534.

38.

Structure determination of a siderophore peucechelin from Streptomyces peucetius.

Kodani S, Komaki H, Suzuki M, Kobayakawa F, Hemmi H.

Biometals. 2015 Oct;28(5):791-801. doi: 10.1007/s10534-015-9866-4. Epub 2015 Jun 18.

PMID:
26085470
39.

Domain characterization of Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator.

Okuda K, Ito T, Goto M, Takenaka T, Hemmi H, Yoshimura T.

J Biochem. 2015 Sep;158(3):225-34. doi: 10.1093/jb/mvv040. Epub 2015 Apr 23.

PMID:
25911692
40.

Isolation and structure determination of new siderophore albachelin from Amycolatopsis alba.

Kodani S, Komaki H, Suzuki M, Hemmi H, Ohnishi-Kameyama M.

Biometals. 2015 Apr;28(2):381-9. doi: 10.1007/s10534-015-9842-z. Epub 2015 Mar 7.

PMID:
25749409
41.

PEGylated D-serine dehydratase as a D-serine reducing agent.

Ito T, Takada H, Isobe K, Suzuki M, Kitaura Y, Hemmi H, Matsuda T, Sasabe J, Yoshimura T.

J Pharm Biomed Anal. 2015 Dec 10;116:34-9. doi: 10.1016/j.jpba.2014.12.044. Epub 2015 Jan 4.

PMID:
25617179
42.

Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator.

Okuda K, Kato S, Ito T, Shiraki S, Kawase Y, Goto M, Kawashima S, Hemmi H, Fukada H, Yoshimura T.

Mol Microbiol. 2015 Jan;95(2):245-57. doi: 10.1111/mmi.12861. Epub 2014 Dec 8.

43.

Homeostasis of thymus-derived Foxp3+ regulatory T cells is controlled by ultraviolet B exposure in the skin.

Yamazaki S, Nishioka A, Kasuya S, Ohkura N, Hemmi H, Kaisho T, Taguchi O, Sakaguchi S, Morita A.

J Immunol. 2014 Dec 1;193(11):5488-97. doi: 10.4049/jimmunol.1400985. Epub 2014 Oct 27.

44.
45.

Isolation and structural determination of a new hydrophobic peptide venepeptide from Streptomyces venezuelae.

Kodani S, Sato K, Hemmi H, Ohnish-Kameyama M.

J Antibiot (Tokyo). 2014 Dec;67(12):839-42. doi: 10.1038/ja.2014.81. Epub 2014 Jun 25. No abstract available.

PMID:
24961708
46.

Reaction mechanism of Zn2+-dependent d-serine dehydratase: role of a conserved tyrosine residue interacting with pyridine ring nitrogen of pyridoxal 5'-phosphate.

Ito T, Matsuoka M, Koga K, Hemmi H, Yoshimura T.

J Biochem. 2014 Sep;156(3):173-80. doi: 10.1093/jb/mvu035. Epub 2014 May 31.

PMID:
24881047
47.

A novel geranylgeranyl reductase from the methanogenic archaeon Methanosarcina acetivorans displays unique regiospecificity.

Ogawa T, Isobe K, Mori T, Asakawa S, Yoshimura T, Hemmi H.

FEBS J. 2014 Jul;281(14):3165-76. doi: 10.1111/febs.12851. Epub 2014 Jun 9.

48.

Olfactory plays a key role in spatiotemporal pathogenesis of cerebral malaria.

Zhao H, Aoshi T, Kawai S, Mori Y, Konishi A, Ozkan M, Fujita Y, Haseda Y, Shimizu M, Kohyama M, Kobiyama K, Eto K, Nabekura J, Horii T, Ishino T, Yuda M, Hemmi H, Kaisho T, Akira S, Kinoshita M, Tohyama K, Yoshioka Y, Ishii KJ, Coban C.

Cell Host Microbe. 2014 May 14;15(5):551-63. doi: 10.1016/j.chom.2014.04.008.

49.

Hindlimb-unloading suppresses B cell population in the bone marrow and peripheral circulation associated with OPN expression in circulating blood cells.

Ezura Y, Nagata J, Nagao M, Hemmi H, Hayata T, Rittling S, Denhardt DT, Noda M.

J Bone Miner Metab. 2015 Jan;33(1):48-54. doi: 10.1007/s00774-014-0568-8. Epub 2014 May 16.

PMID:
24831120
50.

(R)-mevalonate 3-phosphate is an intermediate of the mevalonate pathway in Thermoplasma acidophilum.

Azami Y, Hattori A, Nishimura H, Kawaide H, Yoshimura T, Hemmi H.

J Biol Chem. 2014 Jun 6;289(23):15957-67. doi: 10.1074/jbc.M114.562686. Epub 2014 Apr 22.

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