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Removal of Arterial Vessel Contributions in Susceptibility-Weighted Images for Quantification of Normalized Visible Venous Volume in Children with Sickle Cell Disease

Winchell AM, Song R, Loeffler RB, Wang WC, Hankins JS, Helton KJ, Hillenbrand CM.

J Healthc Eng. 2017;2017. doi: 10.1155/2017/5369385.


Removal of Arterial Vessel Contributions in Susceptibility-Weighted Images for Quantification of Normalized Visible Venous Volume in Children with Sickle Cell Disease.

Winchell AM, Song R, Loeffler RB, Wang WC, Hankins JS, Helton KJ, Hillenbrand CM.

J Healthc Eng. 2017;2017:5369385. doi: 10.1155/2017/5369385. Epub 2017 Aug 28.


Imaging in viral infections of the central nervous system: can images speak for an acutely ill brain?

Maller VV, Bathla G, Moritani T, Helton KJ.

Emerg Radiol. 2017 Jun;24(3):287-300. doi: 10.1007/s10140-016-1463-5. Epub 2016 Nov 16. Review.


Unusual magnetic resonance imaging presentation of post-BMT cerebral toxoplasmosis masquerading as meningoencephalitis and ventriculitis.

Helton KJ, Maron G, Mamcarz E, Leventaki V, Patay Z, Sadighi Z.

Bone Marrow Transplant. 2016 Nov;51(11):1533-1536. doi: 10.1038/bmt.2016.168. Epub 2016 Jun 27. No abstract available.


Hydroxycarbamide treatment and brain MRI/MRA findings in children with sickle cell anaemia.

Nottage KA, Ware RE, Aygun B, Smeltzer M, Kang G, Moen J, Wang WC, Hankins JS, Helton KJ.

Br J Haematol. 2016 Oct;175(2):331-338. doi: 10.1111/bjh.14235. Epub 2016 Sep 8.


Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial.

Ware RE, Davis BR, Schultz WH, Brown RC, Aygun B, Sarnaik S, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone C, Lee MT, Kwiatkowski JL, Jackson S, Miller ST, Roberts C, Heeney MM, Kalfa TA, Nelson S, Imran H, Nottage K, Alvarez O, Rhodes M, Thompson AA, Rothman JA, Helton KJ, Roberts D, Coleman J, Bonner MJ, Kutlar A, Patel N, Wood J, Piller L, Wei P, Luden J, Mortier NA, Stuber SE, Luban NL, Cohen AR, Pressel S, Adams RJ.

Lancet. 2016 Feb 13;387(10019):661-70. doi: 10.1016/S0140-6736(15)01041-7. Epub 2015 Dec 6.


Spatiotemporal Patterns of Tumor Occurrence in Children with Intraocular Retinoblastoma.

King BA, Parra C, Li Y, Helton KJ, Qaddoumi I, Wilson MW, Ogg RJ.

PLoS One. 2015 Jul 31;10(7):e0132932. doi: 10.1371/journal.pone.0132932. eCollection 2015.


Silent cerebral infarcts in very young children with sickle cell anaemia are associated with a higher risk of stroke.

Cancio MI, Helton KJ, Schreiber JE, Smeltzer MP, Kang G, Wang WC.

Br J Haematol. 2015 Oct;171(1):120-9. doi: 10.1111/bjh.13525. Epub 2015 Jun 7.


Comparing segmented ASL perfusion of vascular territories using manual versus semiautomated techniques in children with sickle cell anemia.

Helton KJ, Glass JO, Reddick WE, Paydar A, Zandieh AR, Dave R, Smeltzer MP, Wu S, Hankins J, Aygun B, Ogg RJ.

J Magn Reson Imaging. 2015 Feb;41(2):439-46. doi: 10.1002/jmri.24559. Epub 2014 Jan 8.


Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial.

Helton KJ, Adams RJ, Kesler KL, Lockhart A, Aygun B, Driscoll C, Heeney MM, Jackson SM, Krishnamurti L, Miller ST, Sarnaik SA, Schultz WH, Ware RE; SWiTCH Investigators.

Blood. 2014 Aug 7;124(6):891-8. doi: 10.1182/blood-2013-12-545186. Epub 2014 Jun 9.


Evaluation of SWI in children with sickle cell disease.

Winchell AM, Taylor BA, Song R, Loeffler RB, Grundlehner P, Hankins JS, Wang WC, Ogg RJ, Hillenbrand CM, Helton KJ.

AJNR Am J Neuroradiol. 2014 May;35(5):1016-21. doi: 10.3174/ajnr.A3794. Epub 2013 Nov 21.


Imaging features of medulloepithelioma: report of four cases and review of the literature.

Sansgiri RK, Wilson M, McCarville MB, Helton KJ.

Pediatr Radiol. 2013 Oct;43(10):1344-56. doi: 10.1007/s00247-013-2718-x. Epub 2013 Aug 30. Review.


The effects of propofol on cerebral perfusion MRI in children.

Harreld JH, Helton KJ, Kaddoum RN, Reddick WE, Li Y, Glass JO, Sansgiri R, Ji Q, Feng T, Parish ME, Gajjar A, Patay Z.

Neuroradiology. 2013 Aug;55(8):1049-1056. doi: 10.1007/s00234-013-1187-0. Epub 2013 May 15.


Fludarabine-induced severe necrotizing leukoencephalopathy in pediatric hematopoietic cell transplantation.

Helton KJ, Patay Z, Triplett BM.

Bone Marrow Transplant. 2013 May;48(5):729-31. doi: 10.1038/bmt.2012.196. Epub 2012 Oct 22. No abstract available.


What goes around comes around? Wernicke encephalopathy and the nationwide shortage of intravenous multivitamins revisited.

Perko R, Harreld JH, Helton KJ, Sabin ND, Haidar CE, Wright KD.

J Clin Oncol. 2012 Nov 1;30(31):e318-20. doi: 10.1200/JCO.2012.42.7237. Epub 2012 Sep 24. No abstract available.


The impact of preparation and support procedures for children with sickle cell disease undergoing MRI.

Cejda KR, Smeltzer MP, Hansbury EN, McCarville ME, Helton KJ, Hankins JS.

Pediatr Radiol. 2012 Oct;42(10):1223-8. doi: 10.1007/s00247-012-2422-2. Epub 2012 Jun 19.


Radiation therapy and adjuvant chemotherapy in a patient with a malignant glioneuronal tumor and underlying ataxia telangiectasia: a case report and review of the literature.

DeWire MD, Beltran C, Boop FA, Helton KJ, Ellison DW, McKinnon PJ, Gajjar A, Pai Panandiker AS.

J Clin Oncol. 2013 Jan 1;31(1):e12-4. doi: 10.1200/JCO.2011.40.1430. Epub 2012 Jun 11. No abstract available.


US and MRI of pediatric ocular masses with histopathological correlation.

Brennan RC, Wilson MW, Kaste S, Helton KJ, McCarville MB.

Pediatr Radiol. 2012 Jun;42(6):738-49. doi: 10.1007/s00247-012-2374-6. Epub 2012 Mar 31. Review.


Hemodynamic responses to visual stimulation in children with sickle cell anemia.

Zou P, Helton KJ, Smeltzer M, Li CS, Conklin HM, Gajjar A, Wang WC, Ware RE, Ogg RJ.

Brain Imaging Behav. 2011 Dec;5(4):295-306. doi: 10.1007/s11682-011-9133-4.


Sequencing of local therapy affects the pattern of treatment failure and survival in children with atypical teratoid rhabdoid tumors of the central nervous system.

Pai Panandiker AS, Merchant TE, Beltran C, Wu S, Sharma S, Boop FA, Jenkins JJ, Helton KJ, Wright KD, Broniscer A, Kun LE, Gajjar A.

Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):1756-63. doi: 10.1016/j.ijrobp.2011.02.059. Epub 2011 May 19.


Spinal epidural lipomatosis in children with hematologic malignancies.

Brennan RC, Helton KJ, Pei D, Cheng C, Inaba H, Metzger ML, Howard SC, Rubnitz JE, Ribeiro RC, Sandlund JT, Jeha S, Pui CH, Bhojwani D.

Ann Hematol. 2011 Sep;90(9):1067-74. doi: 10.1007/s00277-011-1183-6. Epub 2011 Feb 22.


Functional neuroimaging to characterize visual system development in children with retinoblastoma.

Barb SM, Rodriguez-Galindo C, Wilson MW, Phillips NS, Zou P, Scoggins MA, Li Y, Qaddoumi I, Helton KJ, Bikhazi G, Haik BG, Ogg RJ.

Invest Ophthalmol Vis Sci. 2011 Apr 20;52(5):2619-26. doi: 10.1167/iovs.10-5600. Print 2011 Apr.


p18Ink4c and p53 Act as tumor suppressors in cyclin D1-driven primitive neuroectodermal tumor.

Saab R, Rodriguez-Galindo C, Matmati K, Rehg JE, Baumer SH, Khoury JD, Billups C, Neale G, Helton KJ, Skapek SX.

Cancer Res. 2009 Jan 15;69(2):440-8. doi: 10.1158/0008-5472.CAN-08-1892.


Arterial spin-labeled perfusion combined with segmentation techniques to evaluate cerebral blood flow in white and gray matter of children with sickle cell anemia.

Helton KJ, Paydar A, Glass J, Weirich EM, Hankins J, Li CS, Smeltzer MP, Wang WC, Ware RE, Ogg RJ.

Pediatr Blood Cancer. 2009 Jan;52(1):85-91. doi: 10.1002/pbc.21745.


MRI abnormalities of the brain in one-year-old children with sickle cell anemia.

Wang WC, Pavlakis SG, Helton KJ, McKinstry RC, Casella JF, Adams RJ, Rees RC; BABY HUG Investigators.

Pediatr Blood Cancer. 2008 Nov;51(5):643-6. doi: 10.1002/pbc.21612.


Diffusion tensor imaging of brainstem tumors: axonal degeneration of motor and sensory tracts.

Helton KJ, Weeks JK, Phillips NS, Zou P, Kun LE, Khan RB, Gajjar A, Fouladi M, Broniscer A, Boop F, Li CS, Ogg RJ.

J Neurosurg Pediatr. 2008 Apr;1(4):270-6. doi: 10.3171/PED/2008/1/4/270.


A phase II study of the farnesyl transferase inhibitor, tipifarnib, in children with recurrent or progressive high-grade glioma, medulloblastoma/primitive neuroectodermal tumor, or brainstem glioma: a Children's Oncology Group study.

Fouladi M, Nicholson HS, Zhou T, Laningham F, Helton KJ, Holmes E, Cohen K, Speights RA, Wright J, Pollack IF; Children's Oncology Group.

Cancer. 2007 Dec 1;110(11):2535-41.


Preservation of spleen and brain function in children with sickle cell anemia treated with hydroxyurea.

Hankins JS, Helton KJ, McCarville MB, Li CS, Wang WC, Ware RE.

Pediatr Blood Cancer. 2008 Feb;50(2):293-7.


Chromosome 17 abnormalities in pediatric neuroblastic tumor with abundant neuropil and true rosettes.

Fuller C, Fouladi M, Gajjar A, Dalton J, Sanford RA, Helton KJ.

Am J Clin Pathol. 2006 Aug;126(2):277-83.


Computer-aided detection of therapy-induced leukoencephalopathy in pediatric acute lymphoblastic leukemia patients treated with intravenous high-dose methotrexate.

Glass JO, Reddick WE, Li CS, Laningham FH, Helton KJ, Pui CH.

Magn Reson Imaging. 2006 Jul;24(6):785-91. Epub 2006 Apr 27.


Diffuse CNS vasculopathy with chronic Epstein-Barr virus infection in X-linked lymphoproliferative disease.

Weeks JK, Helton KJ, Conley ME, Onciu M, Khan RB.

AJNR Am J Neuroradiol. 2006 Apr;27(4):884-6.


Diffusion tensor imaging of tract involvement in children with pontine tumors.

Helton KJ, Phillips NS, Khan RB, Boop FA, Sanford RA, Zou P, Li CS, Langston JW, Ogg RJ.

AJNR Am J Neuroradiol. 2006 Apr;27(4):786-93.


Diffusion tensor imaging of intraaxial tumors at the cervicomedullary and pontomedullary junctions. Report of two cases.

Phillips NS, Sanford RA, Helton KJ, Boop FA, Zou P, Tekautz T, Gajjar A, Ogg RJ.

J Neurosurg. 2005 Dec;103(6 Suppl):557-62.


A quantitative MR imaging assessment of leukoencephalopathy in children treated for acute lymphoblastic leukemia without irradiation.

Reddick WE, Glass JO, Helton KJ, Langston JW, Li CS, Pui CH.

AJNR Am J Neuroradiol. 2005 Oct;26(9):2371-7.


Neuroimaging-detected late transient treatment-induced lesions in pediatric patients with brain tumors.

Helton KJ, Edwards M, Steen RG, Merchant TE, Sapp MV, Boop FA, Langston J.

J Neurosurg. 2005 Mar;102(2 Suppl):179-86.


Prevalence of leukoencephalopathy in children treated for acute lymphoblastic leukemia with high-dose methotrexate.

Reddick WE, Glass JO, Helton KJ, Langston JW, Xiong X, Wu S, Pui CH.

AJNR Am J Neuroradiol. 2005 May;26(5):1263-9. Review.


Brain parenchymal damage after haematopoietic stem cell transplantation for severe sickle cell disease.

Woodard P, Helton KJ, Khan RB, Hale GA, Phipps S, Wang W, Handgretinger R, Cunningham JM.

Br J Haematol. 2005 May;129(4):550-2.


Abnormal hippocampal development in children with medulloblastoma treated with risk-adapted irradiation.

Nagel BJ, Palmer SL, Reddick WE, Glass JO, Helton KJ, Wu S, Xiong X, Kun LE, Gajjar A, Mulhern RK.

AJNR Am J Neuroradiol. 2004 Oct;25(9):1575-82.


Medullomyoblastoma: a radiographic and clinicopathologic analysis of six cases and review of the literature.

Helton KJ, Fouladi M, Boop FA, Perry A, Dalton J, Kun L, Fuller C.

Cancer. 2004 Sep 15;101(6):1445-54. Review.


The impact of a clinical guideline on imaging children with hypertrophic pyloric stenosis.

Helton KJ, Strife JL, Warner BW, Byczkowski TL, Donovan EF.

Pediatr Radiol. 2004 Sep;34(9):733-6. Epub 2004 Jul 28.


Brain metastases of malignant germ cell tumors in children and adolescents.

Spunt SL, Walsh MF, Krasin MJ, Helton KJ, Billups CA, Cain AM, Pappo AS.

Cancer. 2004 Aug 1;101(3):620-6.


Extranodal Rosai-Dorfman disease in children.

Rodriguez-Galindo C, Helton KJ, Sánchez ND, Rieman M, Jeng M, Wang W.

J Pediatr Hematol Oncol. 2004 Jan;26(1):19-24.


Functional MRI and Wada determination of language lateralization: a case of crossed dominance.

Ries ML, Boop FA, Griebel ML, Zou P, Phillips NS, Johnson SC, Williams JP, Helton KJ, Ogg RJ.

Epilepsia. 2004 Jan;45(1):85-9.


Brain injury in children with sickle cell disease: prevalence and etiology.

Steen RG, Xiong X, Langston JW, Helton KJ.

Ann Neurol. 2003 Nov;54(5):564-72.


Brain imaging findings in pediatric patients with sickle cell disease.

Steen RG, Emudianughe T, Hankins GM, Wynn LW, Wang WC, Xiong X, Helton KJ.

Radiology. 2003 Jul;228(1):216-25. Epub 2003 May 29.


Prospective brain imaging evaluation of children with sickle cell trait: initial observations.

Steen RG, Hankins GM, Xiong X, Wang WC, Beil K, Langston JW, Helton KJ.

Radiology. 2003 Jul;228(1):208-15. Epub 2003 May 20. Erratum in: Radiology. 2005 Jun;235(3):1086.


Cognitive impairment in children with hemoglobin SS sickle cell disease: relationship to MR imaging findings and hematocrit.

Steen RG, Miles MA, Helton KJ, Strawn S, Wang W, Xiong X, Mulhern RK.

AJNR Am J Neuroradiol. 2003 Mar;24(3):382-9.


The effect of hydroxyurea on vasculopathy in a child with sickle cell disease.

Helton KJ, Wang WC, Wynn LW, Khan RB, Steen RG.

AJNR Am J Neuroradiol. 2002 Nov-Dec;23(10):1692-6.


Medulloblastoma metastatic to the suprasellar region at diagnosis: a report of six cases with clinicopathologic correlation.

Helton KJ, Gajjar A, Hill DA, Boop FA, Kun LE, Langston JW.

Pediatr Neurosurg. 2002 Sep;37(3):111-7.


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