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Items: 1 to 50 of 55

1.

O-GlcNAc Transferase Regulates Angiogenesis in Idiopathic Pulmonary Arterial Hypertension.

Barnes JW, Tian L, Krick S, Helton ES, Denson RS, Comhair SAA, Dweik RA.

Int J Mol Sci. 2019 Dec 13;20(24). pii: E6299. doi: 10.3390/ijms20246299.

2.

FGF23 Induction of O-Linked N-Acetylglucosamine Regulates IL-6 Secretion in Human Bronchial Epithelial Cells.

Krick S, Helton ES, Hutcheson SB, Blumhof S, Garth JM, Denson RS, Zaharias RS, Wickham H, Barnes JW.

Front Endocrinol (Lausanne). 2018 Nov 27;9:708. doi: 10.3389/fendo.2018.00708. eCollection 2018.

3.

Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neuropathy.

Dong C, Helton ES, Zhou P, Ouyang X, d'Anglemont de Tassigny X, Pascual A, López-Barneo J, Ubogu EE.

Tissue Barriers. 2018;6(2):1-22. doi: 10.1080/21688370.2018.1479570. Epub 2018 Sep 5.

4.

The Human Blood-Nerve Barrier Transcriptome.

Palladino SP, Helton ES, Jain P, Dong C, Crowley MR, Crossman DK, Ubogu EE.

Sci Rep. 2017 Dec 12;7(1):17477. doi: 10.1038/s41598-017-17475-y.

5.

An Assessment of Imaging Informatics for Precision Medicine in Cancer.

Chennubhotla C, Clarke LP, Fedorov A, Foran D, Harris G, Helton E, Nordstrom R, Prior F, Rubin D, Saltz JH, Shalley E, Sharma A.

Yearb Med Inform. 2017 Aug;26(1):110-119. doi: 10.15265/IY-2017-041. Epub 2017 Sep 11. Review.

6.

BRIDG: a domain information model for translational and clinical protocol-driven research.

Becnel LB, Hastak S, Ver Hoef W, Milius RP, Slack M, Wold D, Glickman ML, Brodsky B, Jaffe C, Kush R, Helton E.

J Am Med Inform Assoc. 2017 Sep 1;24(5):882-890. doi: 10.1093/jamia/ocx004.

7.

Fibronectin connecting segment-1 peptide inhibits pathogenic leukocyte trafficking and inflammatory demyelination in experimental models of chronic inflammatory demyelinating polyradiculoneuropathy.

Dong C, Greathouse KM, Beacham RL, Palladino SP, Helton ES, Ubogu EE.

Exp Neurol. 2017 Jun;292:35-45. doi: 10.1016/j.expneurol.2017.02.012. Epub 2017 Feb 16.

8.

Dysregulation of Systemic and Mucosal Humoral Responses to Microbial and Food Antigens as a Factor Contributing to Microbial Translocation and Chronic Inflammation in HIV-1 Infection.

Hel Z, Xu J, Denning WL, Helton ES, Huijbregts RP, Heath SL, Overton ET, Christmann BS, Elson CO, Goepfert PA, Mestecky J.

PLoS Pathog. 2017 Jan 26;13(1):e1006087. doi: 10.1371/journal.ppat.1006087. eCollection 2017 Jan.

9.

A novel method for measuring hydraulic conductivity at the human blood-nerve barrier in vitro.

Helton ES, Palladino S, Ubogu EE.

Microvasc Res. 2017 Jan;109:1-6. doi: 10.1016/j.mvr.2016.08.005. Epub 2016 Aug 31.

10.

The pathogenic relevance of αM-integrin in Guillain-Barré syndrome.

Dong C, Palladino SP, Helton ES, Ubogu EE.

Acta Neuropathol. 2016 Nov;132(5):739-752. Epub 2016 Jul 26.

11.

Modeling leukocyte trafficking at the human blood-nerve barrier in vitro and in vivo geared towards targeted molecular therapies for peripheral neuroinflammation.

Greathouse KM, Palladino SP, Dong C, Helton ES, Ubogu EE.

J Neuroinflammation. 2016 Jan 6;13:3. doi: 10.1186/s12974-015-0469-3. Review.

12.

Inhibition of human cytochrome P450 2E1 and 2A6 by aldehydes: structure and activity relationships.

Kandagatla SK, Mack T, Simpson S, Sollenberger J, Helton E, Raner GM.

Chem Biol Interact. 2014 Aug 5;219:195-202. doi: 10.1016/j.cbi.2014.05.014. Epub 2014 Jun 9.

13.

Immune suppression by neutrophils in HIV-1 infection: role of PD-L1/PD-1 pathway.

Bowers NL, Helton ES, Huijbregts RP, Goepfert PA, Heath SL, Hel Z.

PLoS Pathog. 2014 Mar 13;10(3):e1003993. doi: 10.1371/journal.ppat.1003993. eCollection 2014 Mar.

14.

Hormonal contraception and HIV-1 infection: medroxyprogesterone acetate suppresses innate and adaptive immune mechanisms.

Huijbregts RP, Helton ES, Michel KG, Sabbaj S, Richter HE, Goepfert PA, Hel Z.

Endocrinology. 2013 Mar;154(3):1282-95. doi: 10.1210/en.2012-1850. Epub 2013 Jan 25.

15.

G2E3 is a dual function ubiquitin ligase required for early embryonic development.

Brooks WS, Helton ES, Banerjee S, Venable M, Johnson L, Schoeb TR, Kesterson RA, Crawford DF.

J Biol Chem. 2008 Aug 8;283(32):22304-15. doi: 10.1074/jbc.M803238200. Epub 2008 May 28.

16.

Electronic health records, medical research, and the Tower of Babel.

Kush RD, Helton E, Rockhold FW, Hardison CD.

N Engl J Med. 2008 Apr 17;358(16):1738-40. doi: 10.1056/NEJMsb0800209. No abstract available.

PMID:
18420507
17.

The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63.

Helton ES, Zhang J, Chen X.

Oncogene. 2008 May 1;27(20):2843-50. Epub 2007 Nov 26.

18.

p53 modulation of the DNA damage response.

Helton ES, Chen X.

J Cell Biochem. 2007 Mar 1;100(4):883-96. Review.

PMID:
17031865
20.

T1DBase, a community web-based resource for type 1 diabetes research.

Smink LJ, Helton EM, Healy BC, Cavnor CC, Lam AC, Flamez D, Burren OS, Wang Y, Dolman GE, Burdick DB, Everett VH, Glusman G, Laneri D, Rowen L, Schuilenburg H, Walker NM, Mychaleckyj J, Wicker LS, Eizirik DL, Todd JA, Goodman N.

Nucleic Acids Res. 2005 Jan 1;33(Database issue):D544-9.

21.

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J; MGC Project Team.

Genome Res. 2004 Oct;14(10B):2121-7. Erratum in: Genome Res. 2006 Jun;16(6):804. Morrin, Ryan [corrected to Morin, Ryan].

22.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA; Mammalian Gene Collection Program Team.

Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

23.

The effects of alcohol and provocation on aggressive behavior in men and women.

Giancola PR, Helton EL, Osborne AB, Terry MK, Fuss AM, Westerfield JA.

J Stud Alcohol. 2002 Jan;63(1):64-73.

PMID:
11925061
24.

Effect of L-carnitine treatment for valproate-induced hepatotoxicity.

Bohan TP, Helton E, McDonald I, König S, Gazitt S, Sugimoto T, Scheffner D, Cusmano L, Li S, Koch G.

Neurology. 2001 May 22;56(10):1405-9.

PMID:
11376200
25.

Metabolic aspects of myocardial disease and a role for L-carnitine in the treatment of childhood cardiomyopathy.

Helton E, Darragh R, Francis P, Fricker FJ, Jue K, Koch G, Mair D, Pierpont ME, Prochazka JV, Linn LS, Winter SC.

Pediatrics. 2000 Jun;105(6):1260-70. Erratum in: Pediatrics 2000 Sep;106(3):623.

PMID:
10835067
26.

Survival, lung injury, and lung protein nitration in heterozygous MnSOD knockout mice in hyperoxia.

Jackson RM, Helton ES, Viera L, Ohman T.

Exp Lung Res. 1999 Oct-Nov;25(7):631-46.

PMID:
10598322
27.

Peroxynitrite modulates manganese-containing superoxide dismutase gene expression in lung epithelial cells.

Jackson RM, Parish G, Helton E.

Chest. 1999 Jul;116(1 Suppl):100S-101S. No abstract available.

PMID:
10424621
28.

Peroxynitrite modulates MnSOD gene expression in lung epithelial cells.

Jackson RM, Parish G, Helton ES.

Free Radic Biol Med. 1998 Sep;25(4-5):463-72.

PMID:
9741582
29.

Modulation of rat lung Na+,K(+)-ATPase gene expression by hyperoxia.

Johnson CR, Guo Y, Helton ES, Matalon S, Jackson RM.

Exp Lung Res. 1998 Mar-Apr;24(2):173-88.

PMID:
9555575
30.

Acetyl-L-carnitine deficiency as a cause of altered nerve myo-inositol content, Na,K-ATPase activity, and motor conduction velocity in the streptozotocin-diabetic rat.

Stevens MJ, Lattimer SA, Feldman EL, Helton ED, Millington DS, Sima AA, Greene DA.

Metabolism. 1996 Jul;45(7):865-72.

PMID:
8692023
31.
32.

Plasma carnitine concentrations in pregnancy, cord blood, and neonates and children.

Winter SC, Linn LS, Helton E.

Clin Chim Acta. 1995 Dec 15;243(1):87-93. No abstract available.

PMID:
8747516
33.

The role of L-carnitine in pediatric cardiomyopathy.

Winter S, Jue K, Prochazka J, Francis P, Hamilton W, Linn L, Helton E.

J Child Neurol. 1995 Nov;10 Suppl 2:S45-51.

PMID:
8576569
34.

Comparison of L-carnitine pharmacokinetics with and without baseline correction following administration of single 20-mg/kg intravenous dose.

Sahajwalla CG, Helton ED, Purich ED, Hoppel CL, Cabana BE.

J Pharm Sci. 1995 May;84(5):634-9.

PMID:
7658357
35.
36.

Maximum dosage level in testing low-toxicity chemicals for carcinogenicity in rodents.

Apostolou A, Helton ED.

J Appl Toxicol. 1993 May-Jun;13(3):209-12.

PMID:
8326091
37.

Chronic effects of diethylstilbestrol on estrogen metabolism in the mouse.

Jurek A, Althaus ZA, Slikker W Jr, Helton ED.

J Environ Pathol Toxicol Oncol. 1986 Sep-Dec;7(1-2):197-209.

PMID:
3795012
38.

Effect of short-term administration of sodium saccharin on rhesus monkeys.

Westland JA, Helton ED.

Food Chem Toxicol. 1984 Dec;22(12):931-4.

PMID:
6542544
39.

Synthesis and characterization of the anomeric pair of 17 beta-glucuronides of ethynylestradiol.

Hadd HE, Slikker W Jr, Miller DW, Helton ED, Duax WL, Strong PD, Swenson DC.

J Steroid Biochem. 1983 Jan;18(1):81-7.

PMID:
6865406
40.

Effects of estradiol-17 alpha on nuclear occupancy of the estrogen receptor, stimulation of nuclear type II sites and uterine growth.

Clark JH, Williams M, Upchurch S, Eriksson H, Helton E, Markaverich BM.

J Steroid Biochem. 1982 Feb;16(2):323-8.

PMID:
7078167
41.

Diethylstilbestrol reversal of gonadotropin patterns in infant rhesus monkeys.

Fuller GB, Yates DE, Helton ED, Hobson WC.

J Steroid Biochem. 1981 Dec;15:497-500. No abstract available.

PMID:
6803070
42.

Ethynyl cleavage of 17 alpha-ethynylestradiol in the rhesus monkey.

Raitano LA, Slikker W Jr, Hill DE, Hadd HE, Cairns T, Helton ED.

Drug Metab Dispos. 1981 Mar-Apr;9(2):129-34.

PMID:
6113111
43.

The synthesis and characterization of the glucopyranosiduronic acids of 17 alpha-ethynylestradiol-17 beta.

Hadd HE, Slikker W Jr, Helton ED.

J Steroid Biochem. 1980 Sep;13(9):1107-14. No abstract available.

PMID:
7421249
44.

Transplacental pharmacokinetics and metabolism of diethylstilbestrol and 17 beta-estradiol in the pregnant rhesus monkey.

Hill DE, Slikker W Jr, Helton ED, Lipe GW, Newport GD, Sziszak TJ, Bailey JR.

J Clin Endocrinol Metab. 1980 May;50(5):811-8.

PMID:
6768757
45.

The metabolism of diethylstilbestrol in the rhesus monkey and chimpanzee.

Helton ED, Hill DE, Lipe GW, Sziszak TJ, King JW Jr.

J Environ Pathol Toxicol. 1978 Nov-Dec;2(2):521-37.

PMID:
105073
46.

Metabolism of diethylstilbestrol in the C3H mouse: chromatographic systems for the quantitative analysis of DES metabolic products.

Helton ED, Gough BJ, King JW Jr, Thenot JP, Horning EC.

Steroids. 1978 Apr;31(4):471-84.

PMID:
663980
47.

Toxic agents resulting from the oxidative metabolism of steroid hormones and drugs.

Horning EC, Thenot JP, Helton ED.

J Toxicol Environ Health. 1978 Mar-May;4(2-3):341-61.

PMID:
660665
48.

Synthesis of 17beta-D-glucopyranosiduronic acid of 17alpha-ethynylestradiol.

Helton ED, Hadd HE, Williams MC, Rao PN, Goldzieher JW.

J Steroid Biochem. 1978 Mar;9(3):237-8. No abstract available.

PMID:
206785
49.

Metabolism of 17alpha-ethynylestradiol by intact liver parenchymal cells isolated from mouse and rat.

Helton ED, Casciano DA, Althaus ZR, Plant HD.

J Toxicol Environ Health. 1977 Dec;3(5-6):953-63.

PMID:
599590
50.

Metabolism of ethynyl estrogens.

Helton ED, Goldzieher JW.

J Toxicol Environ Health. 1977 Sep;3(1-2):231-41.

PMID:
411942

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