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Items: 15

1.

Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals.

Tricot T, Helsen N, Kaptein SJF, Neyts J, Verfaillie CM.

PLoS One. 2018 Dec 19;13(12):e0209097. doi: 10.1371/journal.pone.0209097. eCollection 2018.

2.

Effect of Plasma Protein Binding on the Anti-Hepatitis B Virus Activity and Pharmacokinetic Properties of NVR 3-778.

Helsen N, Vervoort T, Vandenbossche J, Lenz O, Monshouwer M, Pauwels F, Snoeys J.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01497-18. doi: 10.1128/AAC.01497-18. Print 2018 Nov.

PMID:
30181376
3.

Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells.

Sambathkumar R, Akkerman R, Dastidar S, Roelandt P, Kumar M, Bajaj M, Mestre Rosa AR, Helsen N, Vanslembrouck V, Kalo E, Khurana S, Laureys J, Gysemans C, Faas MM, de Vos P, Verfaillie CM.

PLoS One. 2018 May 11;13(5):e0197046. doi: 10.1371/journal.pone.0197046. eCollection 2018.

4.

FDG-PET/CT for treatment response assessment in head and neck squamous cell carcinoma: a systematic review and meta-analysis of diagnostic performance.

Helsen N, Van den Wyngaert T, Carp L, Stroobants S.

Eur J Nucl Med Mol Imaging. 2018 Jun;45(6):1063-1071. doi: 10.1007/s00259-018-3978-3. Epub 2018 Feb 24.

PMID:
29478080
5.

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition.

Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, Schmidt BZ, Raitano S, Van Den Bosch L, Nahmias Y, Cathomen T, Struys T, Verfaillie CM.

Stem Cell Reports. 2018 Feb 13;10(2):673. doi: 10.1016/j.stemcr.2018.01.034. No abstract available.

6.

Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate.

Pistoni M, Helsen N, Vanhove J, Boon R, Xu Z, Ordovas L, Verfaillie CM.

PLoS One. 2017 Nov 1;12(11):e0186884. doi: 10.1371/journal.pone.0186884. eCollection 2017.

7.

Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography After Concurrent Chemoradiotherapy in Locally Advanced Head-and-Neck Squamous Cell Cancer: The ECLYPS Study.

Van den Wyngaert T, Helsen N, Carp L, Hakim S, Martens MJ, Hutsebaut I, Debruyne PR, Maes ALM, van Dinther J, Van Laer CG, Hoekstra OS, De Bree R, Meersschout SAE, Lenssen O, Vermorken JB, Van den Weyngaert D, Stroobants S; ECLYPS investigators.

J Clin Oncol. 2017 Oct 20;35(30):3458-3464. doi: 10.1200/JCO.2017.73.5845. Epub 2017 Aug 30.

PMID:
28854069
8.

18F-FDG-PET/CT for the detection of disease in patients with head and neck cancer treated with radiotherapy.

Helsen N, Roothans D, Van Den Heuvel B, Van den Wyngaert T, Van den Weyngaert D, Carp L, Stroobants S.

PLoS One. 2017 Aug 3;12(8):e0182350. doi: 10.1371/journal.pone.0182350. eCollection 2017.

9.

Molecular Imaging of Human Embryonic Stem Cells Stably Expressing Human PET Reporter Genes After Zinc Finger Nuclease-Mediated Genome Editing.

Wolfs E, Holvoet B, Ordovas L, Breuls N, Helsen N, Schönberger M, Raitano S, Struys T, Vanbilloen B, Casteels C, Sampaolesi M, Van Laere K, Lambrichts I, Verfaillie CM, Deroose CM.

J Nucl Med. 2017 Oct;58(10):1659-1665. doi: 10.2967/jnumed.117.189779. Epub 2017 Jun 8.

10.

Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus.

Ordovás L, Boon R, Pistoni M, Chen Y, Sambathkumar R, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Raitano S, Verfaillie CM.

J Vis Exp. 2016 Nov 20;(117). doi: 10.3791/54718.

11.

H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro.

Vanhove J, Pistoni M, Welters M, Eggermont K, Vanslembrouck V, Helsen N, Boon R, Najimi M, Sokal E, Collas P, Voncken JW, Verfaillie CM.

Stem Cell Reports. 2016 Aug 9;7(2):192-206. doi: 10.1016/j.stemcr.2016.06.013. Epub 2016 Jul 28.

12.

Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication.

Helsen N, Debing Y, Paeshuyse J, Dallmeier K, Boon R, Coll M, Sancho-Bru P, Claes C, Neyts J, Verfaillie CM.

J Hepatol. 2016 Mar;64(3):565-73. doi: 10.1016/j.jhep.2015.11.013. Epub 2015 Nov 25.

13.

Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition.

Ordovás L, Boon R, Pistoni M, Chen Y, Wolfs E, Guo W, Sambathkumar R, Bobis-Wozowicz S, Helsen N, Vanhove J, Berckmans P, Cai Q, Vanuytsel K, Eggermont K, Vanslembrouck V, Schmidt BZ, Raitano S, Van Den Bosch L, Nahmias Y, Cathomen T, Struys T, Verfaillie CM.

Stem Cell Reports. 2015 Nov 10;5(5):918-931. doi: 10.1016/j.stemcr.2015.09.004. Epub 2015 Oct 8. Erratum in: Stem Cell Reports. 2018 Feb 13;10 (2):673.

14.

Understanding the molecular mechanism of host-based statin resistance in hepatitis C virus replicon containing cells.

Delang L, Scheers E, Grabner M, Verpaalen B, Helsen N, Vanstreels E, Daelemans D, Verfaillie C, Neyts J.

Biochem Pharmacol. 2015 Aug 1;96(3):190-201. doi: 10.1016/j.bcp.2015.06.003. Epub 2015 Jun 9.

PMID:
26070251
15.

Tissue-type plasminogen activator-binding RNA aptamers inhibiting low-density lipoprotein receptor family-mediated internalisation.

Bjerregaard N, Bøtkjær KA, Helsen N, Andreasen PA, Dupont DM.

Thromb Haemost. 2015 Jul;114(1):139-49. doi: 10.1160/TH14-08-0686. Epub 2015 Apr 9.

PMID:
25855589

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