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Items: 1 to 20 of 23

1.

New insights into the evolutionary conservation of the sole PIKK pseudokinase Tra1/TRRAP.

Elías-Villalobos A, Fort P, Helmlinger D.

Biochem Soc Trans. 2019 Nov 26. pii: BST20180496. doi: 10.1042/BST20180496. [Epub ahead of print]

PMID:
31769470
2.

Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes in yeast.

Elías-Villalobos A, Toullec D, Faux C, Séveno M, Helmlinger D.

Nat Commun. 2019 Nov 20;10(1):5237. doi: 10.1038/s41467-019-13243-w.

3.

[The TOR SAGA to the rescue of starved yeast cells].

Laboucarié T, Helmlinger D.

Med Sci (Paris). 2018 Aug-Sep;34(8-9):645-648. doi: 10.1051/medsci/20183408005. Epub 2018 Sep 19. French. No abstract available.

4.

TORC1 and TORC2 converge to regulate the SAGA co-activator in response to nutrient availability.

Laboucarié T, Detilleux D, Rodriguez-Mias RA, Faux C, Romeo Y, Franz-Wachtel M, Krug K, Maček B, Villén J, Petersen J, Helmlinger D.

EMBO Rep. 2017 Dec;18(12):2197-2218. doi: 10.15252/embr.201744942. Epub 2017 Oct 27.

5.

Sharing the SAGA.

Helmlinger D, Tora L.

Trends Biochem Sci. 2017 Nov;42(11):850-861. doi: 10.1016/j.tibs.2017.09.001. Epub 2017 Sep 27. Review.

6.

Histone deacetylases: revealing the molecular base of dimorphism in pathogenic fungi.

Elías-Villalobos A, Helmlinger D, Ibeas JI.

Microb Cell. 2015 Nov 4;2(12):491-493. doi: 10.15698/mic2015.11.240.

7.

The Hos2 Histone Deacetylase Controls Ustilago maydis Virulence through Direct Regulation of Mating-Type Genes.

Elías-Villalobos A, Fernández-Álvarez A, Moreno-Sánchez I, Helmlinger D, Ibeas JI.

PLoS Pathog. 2015 Aug 28;11(8):e1005134. doi: 10.1371/journal.ppat.1005134. eCollection 2015 Aug.

8.

New insights into the SAGA complex from studies of the Tra1 subunit in budding and fission yeast.

Helmlinger D.

Transcription. 2012 Jan-Feb;3(1):13-8. doi: 10.4161/trns.3.1.19271.

PMID:
22456315
9.

Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex.

Helmlinger D, Marguerat S, Villén J, Swaney DL, Gygi SP, Bähler J, Winston F.

EMBO J. 2011 Jun 3;30(14):2843-52. doi: 10.1038/emboj.2011.181.

10.

The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8.

Helmlinger D, Marguerat S, Villén J, Gygi SP, Bähler J, Winston F.

Genes Dev. 2008 Nov 15;22(22):3184-95. doi: 10.1101/gad.1719908.

11.

Long-term engraftment of systemically transplanted, gene-modified bone marrow-derived cells in the adult mouse retina.

Boettcher C, Ulbricht E, Helmlinger D, Mack AF, Reichenbach A, Wiedemann P, Wagner HJ, Seeliger MW, Bringmann A, Priller J.

Br J Ophthalmol. 2008 Feb;92(2):272-5. doi: 10.1136/bjo.2007.126318.

PMID:
18227206
12.

[Role of chromatin alterations in neurodegeneration induced by polyglutamine-expanded ataxin-7].

Helmlinger D, Tora L, Devys D.

Med Sci (Paris). 2006 Aug-Sep;22(8-9):700-2. French. No abstract available.

13.

Transcriptional alterations and chromatin remodeling in polyglutamine diseases.

Helmlinger D, Tora L, Devys D.

Trends Genet. 2006 Oct;22(10):562-70. Epub 2006 Sep 5. Review.

PMID:
16911843
14.

Both normal and polyglutamine- expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase- containing complexes.

Helmlinger D, Hardy S, Eberlin A, Devys D, Tora L.

Biochem Soc Symp. 2006;(73):155-63.

PMID:
16626296
15.

Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction.

Helmlinger D, Hardy S, Abou-Sleymane G, Eberlin A, Bowman AB, Gansmüller A, Picaud S, Zoghbi HY, Trottier Y, Tora L, Devys D.

PLoS Biol. 2006 Mar;4(3):e67. Epub 2006 Feb 28.

16.

Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program.

Abou-Sleymane G, Chalmel F, Helmlinger D, Lardenois A, Thibault C, Weber C, Mérienne K, Mandel JL, Poch O, Devys D, Trottier Y.

Hum Mol Genet. 2006 Mar 1;15(5):691-703. Epub 2006 Jan 24.

PMID:
16434483
17.

Retinal cell type expression specificity of HIV-1-derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter.

Bemelmans AP, Bonnel S, Houhou L, Dufour N, Nandrot E, Helmlinger D, Sarkis C, Abitbol M, Mallet J.

J Gene Med. 2005 Oct;7(10):1367-74.

PMID:
15966018
18.

Hsp70 and Hsp40 chaperones do not modulate retinal phenotype in SCA7 mice.

Helmlinger D, Bonnet J, Mandel JL, Trottier Y, Devys D.

J Biol Chem. 2004 Dec 31;279(53):55969-77. Epub 2004 Oct 19.

19.

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.

Helmlinger D, Hardy S, Sasorith S, Klein F, Robert F, Weber C, Miguet L, Potier N, Van-Dorsselaer A, Wurtz JM, Mandel JL, Tora L, Devys D.

Hum Mol Genet. 2004 Jun 15;13(12):1257-65. Epub 2004 Apr 28.

PMID:
15115762
20.

Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model.

Helmlinger D, Abou-Sleymane G, Yvert G, Rousseau S, Weber C, Trottier Y, Mandel JL, Devys D.

J Neurosci. 2004 Feb 25;24(8):1881-7.

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