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Items: 1 to 50 of 115

1.

Neuromyelitis optica spectrum disorders and pregnancy: relapse-preventive measures and personalized treatment strategies.

Borisow N, Hellwig K, Paul F.

EPMA J. 2018 Aug 10;9(3):249-256. doi: 10.1007/s13167-018-0143-9. eCollection 2018 Sep. Review.

PMID:
30174761
2.

Ovarian Reserve in Women With Neuromyelitis Optica Spectrum Disorder.

Thöne J, Lichtenberg S, Stahl A, Pache F, Kleiter I, Ruprecht K, Gold R, Hellwig K.

Front Neurol. 2018 Jun 19;9:446. doi: 10.3389/fneur.2018.00446. eCollection 2018.

3.

Prevalence and risk factors for bluetongue in the State of São Paulo, Brazil.

da Silva TG, Lima MS, Spedicato M, Carmine I, Teodori L, Leone A, Martins MSN, Buchala FG, Hellwig KS, de Campos Nogueira Romaldini AH, De Stefano E, Savini G, Pituco EM.

Vet Med Sci. 2018 Jul 2. doi: 10.1002/vms3.113. [Epub ahead of print]

4.

Tryptophan immunoadsorption during pregnancy and breastfeeding in patients with acute relapse of multiple sclerosis and neuromyelitis optica.

Hoffmann F, Kraft A, Heigl F, Mauch E, Koehler J, Harms L, Kümpfel T, Köhler W, Ehrlich S, Bayas A, Weinmann-Menke J, Beuker C, Henn KH, Ayzenberg I, Ellrichmann G, Hellwig K, Klingel R, Fassbender CM, Fritz H, Slowinski T, Weihprecht H, Brand M, Stiegler T, Galle J, Schimrigk S.

Ther Adv Neurol Disord. 2018 May 28;11:1756286418774973. doi: 10.1177/1756286418774973. eCollection 2018.

5.

Alemtuzumab as rescue therapy in a cohort of 50 relapsing-remitting MS patients with breakthrough disease on fingolimod: a multi-center observational study.

Huhn K, Bayas A, Doerck S, Frank B, Gerbershagen K, Hellwig K, Kallmann B, Kleinschnitz C, Kleiter I, Lee DH, Limmroth V, Mäurer M, Meuth S, Rieckmann P, Ruck T, Gold R, Linker RA.

J Neurol. 2018 Jul;265(7):1521-1527. doi: 10.1007/s00415-018-8871-2. Epub 2018 Apr 25.

PMID:
29696498
6.

[Neuromyelitis optica spectrum disorder and pregnancy].

Borisow N, Hellwig K, Paul F.

Nervenarzt. 2018 Jun;89(6):666-673. doi: 10.1007/s00115-018-0486-4. Review. German.

PMID:
29383411
7.

Eroding Abscess After use of MYNX Closure Device.

Hellwig K, Regus S.

Eur J Vasc Endovasc Surg. 2018 Apr;55(4):576. doi: 10.1016/j.ejvs.2017.12.018. Epub 2018 Jan 20. No abstract available.

PMID:
29371035
8.

A comparative analysis of human bone marrow-resident and peripheral memory B cells.

Becker SC, Szyska M, Mensen A, Hellwig K, Otto R, Olfe L, Volk HD, Dörner T, Dörken B, Scheibenbogen C, Schröder J, Hocke AC, Na IK.

J Allergy Clin Immunol. 2018 May;141(5):1911-1913.e7. doi: 10.1016/j.jaci.2017.12.983. Epub 2018 Jan 31. No abstract available.

PMID:
29355676
9.

Natalizumab during pregnancy and lactation.

Proschmann U, Thomas K, Thiel S, Hellwig K, Ziemssen T.

Mult Scler. 2018 Oct;24(12):1627-1634. doi: 10.1177/1352458517728813. Epub 2017 Aug 31.

PMID:
28857686
10.

Breastfeeding, ovulatory years, and risk of multiple sclerosis.

Langer-Gould A, Smith JB, Hellwig K, Gonzales E, Haraszti S, Koebnick C, Xiang A.

Neurology. 2017 Aug 8;89(6):563-569. doi: 10.1212/WNL.0000000000004207. Epub 2017 Jul 12.

11.

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response.

Stellmann JP, Krumbholz M, Friede T, Gahlen A, Borisow N, Fischer K, Hellwig K, Pache F, Ruprecht K, Havla J, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Young KL, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Zettl U, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Kleiter I; NEMOS (Neuromyelitis Optica Study Group).

J Neurol Neurosurg Psychiatry. 2017 Aug;88(8):639-647. doi: 10.1136/jnnp-2017-315603. Epub 2017 Jun 1.

12.

Treatment of multiple sclerosis during pregnancy - safety considerations.

Thöne J, Thiel S, Gold R, Hellwig K.

Expert Opin Drug Saf. 2017 May;16(5):523-534. doi: 10.1080/14740338.2017.1311321. Epub 2017 Apr 17. Review.

PMID:
28333552
13.

Successful pregnancy after natalizumab-associated progressive multifocal leukoencephalopathy in a patient with multiple sclerosis.

Pitarokoili K, Hellwig K, Lukas C, Gold R.

Mult Scler. 2017 Mar;23(3):483-486. doi: 10.1177/1352458516678475. Epub 2016 Nov 12.

PMID:
28260421
14.

[Minor Victims of Violent Acts in the Context of the Victim Reparation Law].

Hellwig K, Kröger C, Franke S, Wehrmeyer M, Heinrichs N.

Z Kinder Jugendpsychiatr Psychother. 2018 Mar;46(2):123-132. doi: 10.1024/1422-4917/a000508. Epub 2017 Feb 6. German.

PMID:
28165300
15.

Influence of female sex and fertile age on neuromyelitis optica spectrum disorders.

Borisow N, Kleiter I, Gahlen A, Fischer K, Wernecke KD, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Weissert R, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Winkelmann A, Marouf W, Rückriem L, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Hellwig K; NEMOS (Neuromyelitis Optica Study Group).

Mult Scler. 2017 Jul;23(8):1092-1103. doi: 10.1177/1352458516671203. Epub 2016 Oct 6.

PMID:
27758954
16.

Synthesis, Electrochemical Characterization, and Linear Free Energy Relationship of 1,3-Diphenyl-6-alkyl/arylfulvenes.

Godman NP, Adas SK, Hellwig KM, Ball DW, Balaich GJ, Iacono ST.

J Org Chem. 2016 Oct 21;81(20):9630-9638. Epub 2016 Oct 12.

PMID:
27689910
17.

Predictors of severity and functional outcome in natalizumab-associated progressive multifocal leukoencephalopathy.

Hoepner R, Kolb EM, Dahlhaus S, Hellwig K, Adams O, Kleiter I, Salmen A, Schneider R, Lukas C, Chan A, Berger JR, Gold R.

Mult Scler. 2017 May;23(6):830-835. doi: 10.1177/1352458516667241. Epub 2016 Sep 6.

PMID:
27600113
18.

Plasmapheresis and immunoadsorption in patients with steroid refractory multiple sclerosis relapses.

Faissner S, Nikolayczik J, Chan A, Hellwig K, Gold R, Yoon MS, Haghikia A.

J Neurol. 2016 Jun;263(6):1092-8. doi: 10.1007/s00415-016-8105-4. Epub 2016 Apr 2.

PMID:
27039388
19.

Oral Contraceptives and Multiple Sclerosis/Clinically Isolated Syndrome Susceptibility.

Hellwig K, Chen LH, Stancyzk FZ, Langer-Gould AM.

PLoS One. 2016 Mar 7;11(3):e0149094. doi: 10.1371/journal.pone.0149094. eCollection 2016.

20.

Relevance of endoglin, IL-1α, IL-1β and anti-ovarian antibodies in females with multiple sclerosis.

Thöne J, Kleiter I, Stahl A, Ellrichmann G, Gold R, Hellwig K.

J Neurol Sci. 2016 Mar 15;362:240-3. doi: 10.1016/j.jns.2016.01.057. Epub 2016 Jan 28.

PMID:
26944156
21.

[Monitoring of blood parameters under course-modified MS therapy : Substance-specific relevance and current recommendations for action].

Klotz L, Berthele A, Brück W, Chan A, Flachenecker P, Gold R, Haghikia A, Hellwig K, Hemmer B, Hohlfeld R, Korn T, Kümpfel T, Lang M, Limmroth V, Linker RA, Meier U, Meuth SG, Paul F, Salmen A, Stangel M, Tackenberg B, Tumani H, Warnke C, Weber MS, Ziemssen T, Zipp F, Wiendl H.

Nervenarzt. 2016 Jun;87(6):645-59. doi: 10.1007/s00115-016-0077-1. Review. German.

PMID:
26927677
22.

Breastfeeding and Disease-Modifying Therapy for Multiple Sclerosis--Reply.

Hellwig K, Langer-Gould AM.

JAMA Neurol. 2016 Apr;73(4):480-1. doi: 10.1001/jamaneurol.2015.4821. No abstract available.

PMID:
26926044
23.

Interferon-beta exposure during first trimester is safe in women with multiple sclerosis-A prospective cohort study from the German Multiple Sclerosis and Pregnancy Registry.

Thiel S, Langer-Gould A, Rockhoff M, Haghikia A, Queisser-Wahrendorf A, Gold R, Hellwig K.

Mult Scler. 2016 May;22(6):801-9. doi: 10.1177/1352458516634872. Epub 2016 Feb 26.

PMID:
26920382
24.

Efficacy of glatiramer acetate in neuromyelitis optica spectrum disorder: a multicenter retrospective study.

Ayzenberg I, Schöllhammer J, Hoepner R, Hellwig K, Ringelstein M, Aktas O, Kümpfel T, Krumbholz M, Trebst C, Paul F, Pache F, Obermann M, Zeltner L, Schwab M, Berthele A, Jarius S, Kleiter I; Neuromyelitis Optica Study Group.

J Neurol. 2016 Mar;263(3):575-82. doi: 10.1007/s00415-015-7991-1. Epub 2016 Jan 25.

PMID:
26810718
25.

Glatiramer acetate during early pregnancy: A prospective cohort study.

Herbstritt S, Langer-Gould A, Rockhoff M, Haghikia A, Queisser-Wahrendorf A, Gold R, Hellwig K.

Mult Scler. 2016 May;22(6):810-6. doi: 10.1177/1352458515623366. Epub 2016 Jan 11.

PMID:
26754804
26.

Multiple sclerosis in men: management considerations.

Bove R, McHenry A, Hellwig K, Houtchens M, Razaz N, Smyth P, Tremlett H, Sadovnick AD, Rintell D.

J Neurol. 2016 Jul;263(7):1263-73. doi: 10.1007/s00415-015-8005-z. Epub 2016 Jan 2. Review.

PMID:
26725085
27.

Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer's disease.

Hellwig K, Kvartsberg H, Portelius E, Andreasson U, Oberstein TJ, Lewczuk P, Blennow K, Kornhuber J, Maler JM, Zetterberg H, Spitzer P.

Alzheimers Res Ther. 2015 Dec 24;7:74. doi: 10.1186/s13195-015-0161-y.

28.

Multiple sclerosis and family planning.

Hellwig K.

Neurodegener Dis Manag. 2015;5(6 Suppl):39-42. doi: 10.2217/nmt.15.61. Review. No abstract available.

PMID:
26611271
29.

Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses.

Kleiter I, Gahlen A, Borisow N, Fischer K, Wernecke KD, Wegner B, Hellwig K, Pache F, Ruprecht K, Havla J, Krumbholz M, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Stellmann JP, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker R, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Winkelmann A, Marouf W, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C; Neuromyelitis Optica Study Group.

Ann Neurol. 2016 Feb;79(2):206-16. doi: 10.1002/ana.24554. Epub 2015 Nov 26.

PMID:
26537743
30.

Exclusive Breastfeeding and the Effect on Postpartum Multiple Sclerosis Relapses.

Hellwig K, Rockhoff M, Herbstritt S, Borisow N, Haghikia A, Elias-Hamp B, Menck S, Gold R, Langer-Gould A.

JAMA Neurol. 2015 Oct;72(10):1132-8. doi: 10.1001/jamaneurol.2015.1806. Erratum in: JAMA Neurol. 2016 Apr;73(4):481.

PMID:
26322399
31.

Update on biomarkers in neuromyelitis optica.

Melamed E, Levy M, Waters PJ, Sato DK, Bennett JL, John GR, Hooper DC, Saiz A, Bar-Or A, Kim HJ, Pandit L, Leite MI, Asgari N, Kissani N, Hintzen R, Marignier R, Jarius S, Marcelletti J, Smith TJ, Yeaman MR, Han MH, Aktas O, Apiwattanakul M, Banwell B, Bichuetti D, Broadley S, Cabre P, Chitnis T, De Seze J, Fujihara K, Greenberg B, Hellwig K, Iorio R, Jarius S, Klawiter E, Kleiter I, Lana-Peixoto M, Nakashima, O'Connor K, Palace J, Paul F, Prayoonwiwat N, Ruprecht K, Stuve O, Tedder T, Tenembaum S, Garrahan JP, Aires B, van Herle K, van Pelt D, Villoslada P, Waubant E, Weinshenker B, Wingerchuk D, Würfel J, Zamvil S.

Neurol Neuroimmunol Neuroinflamm. 2015 Jul 23;2(4):e134. doi: 10.1212/NXI.0000000000000134. eCollection 2015 Aug. Review.

32.

Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy controls.

Kvartsberg H, Portelius E, Andreasson U, Brinkmalm G, Hellwig K, Lelental N, Kornhuber J, Hansson O, Minthon L, Spitzer P, Maler JM, Zetterberg H, Blennow K, Lewczuk P.

Alzheimers Res Ther. 2015 Jul 1;7(1):40. doi: 10.1186/s13195-015-0124-3. eCollection 2015.

33.

Combinations of susceptibility genes are associated with higher risk for multiple sclerosis and imply disease course specificity.

Akkad DA, Olischewsky A, Reiner F, Hellwig K, Esser S, Epplen JT, Curk T, Gold R, Haghikia A.

PLoS One. 2015 May 26;10(5):e0127632. doi: 10.1371/journal.pone.0127632. eCollection 2015.

34.

Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder.

Kremer S, Renard F, Achard S, Lana-Peixoto MA, Palace J, Asgari N, Klawiter EC, Tenembaum SN, Banwell B, Greenberg BM, Bennett JL, Levy M, Villoslada P, Saiz A, Fujihara K, Chan KH, Schippling S, Paul F, Kim HJ, de Seze J, Wuerfel JT; Guthy-Jackson Charitable Foundation (GJCF) Neuromyelitis Optica (NMO) International Clinical Consortium and Biorepository, Cabre P, Marignier R, Tedder T, van Pelt D, Broadley S, Chitnis T, Wingerchuk D, Pandit L, Leite MI, Apiwattanakul M, Kleiter I, Prayoonwiwat N, Han M, Hellwig K, van Herle K, John G, Hooper DC, Nakashima I, Sato D, Yeaman MR, Waubant E, Zamvil S, Stüve O, Aktas O, Smith TJ, Jacob A, O'Connor K.

JAMA Neurol. 2015 Jul;72(7):815-22. doi: 10.1001/jamaneurol.2015.0248. Review.

35.

Long-term Therapy With Interleukin 6 Receptor Blockade in Highly Active Neuromyelitis Optica Spectrum Disorder.

Ringelstein M, Ayzenberg I, Harmel J, Lauenstein AS, Lensch E, Stögbauer F, Hellwig K, Ellrichmann G, Stettner M, Chan A, Hartung HP, Kieseier B, Gold R, Aktas O, Kleiter I.

JAMA Neurol. 2015 Jul;72(7):756-63. doi: 10.1001/jamaneurol.2015.0533.

PMID:
25985228
36.

Increasing the inspiratory time and I:E ratio during mechanical ventilation aggravates ventilator-induced lung injury in mice.

Müller-Redetzky HC, Felten M, Hellwig K, Wienhold SM, Naujoks J, Opitz B, Kershaw O, Gruber AD, Suttorp N, Witzenrath M.

Crit Care. 2015 Jan 28;19:23. doi: 10.1186/s13054-015-0759-2.

37.

Management of multiple sclerosis during pregnancy and the reproductive years: a systematic review.

Bove R, Alwan S, Friedman JM, Hellwig K, Houtchens M, Koren G, Lu E, McElrath TF, Smyth P, Tremlett H, Sadovnick AD.

Obstet Gynecol. 2014 Dec;124(6):1157-68. doi: 10.1097/AOG.0000000000000541. Review.

PMID:
25415167
38.

Moxifloxacin is not anti-inflammatory in experimental pneumococcal pneumonia.

Müller-Redetzky HC, Wienhold SM, Berg J, Hocke AC, Hippenstiel S, Hellwig K, Gutbier B, Opitz B, Neudecker J, Rückert J, Gruber AD, Kershaw O, Mayer K, Suttorp N, Witzenrath M.

J Antimicrob Chemother. 2015 Mar;70(3):830-40. doi: 10.1093/jac/dku446. Epub 2014 Nov 17.

PMID:
25406299
39.

Pregnancy in multiple sclerosis.

Hellwig K.

Eur Neurol. 2014;72 Suppl 1:39-42. doi: 10.1159/000367640. Epub 2014 Sep 26.

40.

Pregnancy and fetal outcomes following natalizumab exposure in pregnancy. A prospective, controlled observational study.

Ebrahimi N, Herbstritt S, Gold R, Amezcua L, Koren G, Hellwig K.

Mult Scler. 2015 Feb;21(2):198-205. doi: 10.1177/1352458514546790. Epub 2014 Aug 26.

PMID:
25159275
41.

Serum anti-Müllerian hormone levels in reproductive-age women with relapsing-remitting multiple sclerosis.

Thöne J, Kollar S, Nousome D, Ellrichmann G, Kleiter I, Gold R, Hellwig K.

Mult Scler. 2015 Jan;21(1):41-7. doi: 10.1177/1352458514540843. Epub 2014 Aug 21.

PMID:
25145691
42.

Predictors for multiple sclerosis relapses after switching from natalizumab to fingolimod.

Hoepner R, Havla J, Eienbröker C, Tackenberg B, Hellwig K, Meinl I, Hohlfeld R, Gold R, Kümpfel T, Kleiter I.

Mult Scler. 2014 Nov;20(13):1714-20. doi: 10.1177/1352458514533398. Epub 2014 May 19.

PMID:
24842961
43.

Natalizumab use during the third trimester of pregnancy.

Haghikia A, Langer-Gould A, Rellensmann G, Schneider H, Tenenbaum T, Elias-Hamp B, Menck S, Zimmermann J, Herbstritt S, Marziniak M, Kümpfel T, Meinl I, Plavina T, Gold R, Hellwig K.

JAMA Neurol. 2014 Jul 1;71(7):891-5. doi: 10.1001/jamaneurol.2014.209. Review.

PMID:
24821217
44.

Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin.

Müller-Redetzky HC, Will D, Hellwig K, Kummer W, Tschernig T, Pfeil U, Paddenberg R, Menger MD, Kershaw O, Gruber AD, Weissmann N, Hippenstiel S, Suttorp N, Witzenrath M.

Crit Care. 2014 Apr 14;18(2):R73. doi: 10.1186/cc13830.

45.

Prophylactic antiepileptic treatment reduces seizure frequency in natalizumab-associated progressive multifocal leukoencephalopathy.

Hoepner R, Dahlhaus S, Kollar S, Zurawski B, Chan A, Kleiter I, Gold R, Hellwig K.

Ther Adv Neurol Disord. 2014 Jan;7(1):3-6. doi: 10.1177/1756285613503515.

46.

One can prevent post-partum MS relapses by exclusive breast feeding: yes.

Langer-Gould A, Hellwig K.

Mult Scler. 2013 Oct;19(12):1567-8. doi: 10.1177/1352458513505161. No abstract available.

PMID:
24132002
47.

Neuromyelitis optica and pregnancy during therapeutic B cell depletion: infant exposure to anti-AQP4 antibody and prevention of rebound relapses with low-dose rituximab postpartum.

Ringelstein M, Harmel J, Distelmaier F, Ingwersen J, Menge T, Hellwig K, Kieseier B, Mayatepek E, Hartung HP, Kuempfel T, Aktas O.

Mult Scler. 2013 Oct;19(11):1544-7. doi: 10.1177/1352458513498125. Epub 2013 Jul 25.

PMID:
23886825
48.

Is It Too Early to Predict the Failure of Natalizumab in NMO?-Reply.

Kleiter I, Hellwig K, Berthele A, Kümpfel T, Linker RA, Hartung HP, Paul F, Aktas O; Neuromyelitis Optica Study Group (NEMOS).

Arch Neurol. 2012 Aug 1;69(8):1085-6. doi: 10.1001/archneurol.2012.1316. No abstract available.

PMID:
23753805
49.

Disease course and outcome of 15 monocentrically treated natalizumab-associated progressive multifocal leukoencephalopathy patients.

Dahlhaus S, Hoepner R, Chan A, Kleiter I, Adams O, Lukas C, Hellwig K, Gold R.

J Neurol Neurosurg Psychiatry. 2013 Oct;84(10):1068-74. doi: 10.1136/jnnp-2013-304897. Epub 2013 Apr 19.

50.

Artificial reproductive techniques in multiple sclerosis.

Hellwig K, Correale J.

Clin Immunol. 2013 Nov;149(2):219-24. doi: 10.1016/j.clim.2013.02.001. Epub 2013 Feb 15. Review.

PMID:
23507401

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