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Items: 38

1.

Immune evasion of the human pathogen Pseudomonas aeruginosa: elongation factor Tuf is a factor H and plasminogen binding protein.

Kunert A, Losse J, Gruszin C, Hühn M, Kaendler K, Mikkat S, Volke D, Hoffmann R, Jokiranta TS, Seeberger H, Moellmann U, Hellwage J, Zipfel PF.

J Immunol. 2007 Sep 1;179(5):2979-88.

2.

Borrelia burgdorferi binding of host complement regulator factor H is not required for efficient mammalian infection.

Woodman ME, Cooley AE, Miller JC, Lazarus JJ, Tucker K, Bykowski T, Botto M, Hellwage J, Wooten RM, Stevenson B.

Infect Immun. 2007 Jun;75(6):3131-9. Epub 2007 Apr 9.

3.

Two factor H-related proteins from the mouse: expression analysis and functional characterization.

Hellwage J, Eberle F, Babuke T, Seeberger H, Richter H, Kunert A, Härtl A, Zipfel PF, Jokiranta TS, Józsi M.

Immunogenetics. 2006 Nov;58(11):883-93. Epub 2006 Oct 7.

PMID:
17028856
4.

LfhA, a novel factor H-binding protein of Leptospira interrogans.

Verma A, Hellwage J, Artiushin S, Zipfel PF, Kraiczy P, Timoney JF, Stevenson B.

Infect Immun. 2006 May;74(5):2659-66.

5.

Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site.

Jokiranta TS, Cheng ZZ, Seeberger H, Jòzsi M, Heinen S, Noris M, Remuzzi G, Ormsby R, Gordon DL, Meri S, Hellwage J, Zipfel PF.

Am J Pathol. 2005 Oct;167(4):1173-81.

6.

Comparison of surface recognition and C3b binding properties of mouse and human complement factor H.

Cheng ZZ, Hellwage J, Seeberger H, Zipfel PF, Meri S, Jokiranta TS.

Mol Immunol. 2006 Mar;43(7):972-9. Epub 2005 Jul 14.

PMID:
16023208
7.

Complement factor H as a marker for detection of bladder cancer.

Cheng ZZ, Corey MJ, Pärepalo M, Majno S, Hellwage J, Zipfel PF, Kinders RJ, Raitanen M, Meri S, Jokiranta TS.

Clin Chem. 2005 May;51(5):856-63. Epub 2005 Mar 17.

PMID:
15774575
8.

Factor H binds to washed human platelets.

Vaziri-Sani F, Hellwage J, Zipfel PF, Sjöholm AG, Iancu R, Karpman D.

J Thromb Haemost. 2005 Jan;3(1):154-62.

9.

Immunological characterization of the complement regulator factor H-binding CRASP and Erp proteins of Borrelia burgdorferi.

Kraiczy P, Hartmann K, Hellwage J, Skerka C, Kirschfink M, Brade V, Zipfel PF, Wallich R, Stevenson B.

Int J Med Microbiol. 2004 Apr;293 Suppl 37:152-7.

PMID:
15146998
10.
11.

Complement resistance of Borrelia burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins.

Kraiczy P, Hellwage J, Skerka C, Becker H, Kirschfink M, Simon MM, Brade V, Zipfel PF, Wallich R.

J Biol Chem. 2004 Jan 23;279(4):2421-9. Epub 2003 Nov 7.

12.

Pig complement regulator factor H: molecular cloning and functional characterization.

Hegasy GA, Willhoeft U, Majno SA, Seeberger H, Zipfel PF, Hellwage J.

Immunogenetics. 2003 Oct;55(7):462-71. Epub 2003 Sep 27.

PMID:
14517701
13.

Release of endogenous anti-inflammatory complement regulators FHL-1 and factor H protects synovial fibroblasts during rheumatoid arthritis.

Friese MA, Manuelian T, Junnikkala S, Hellwage J, Meri S, Peter HH, Gordon DL, Eibel H, Zipfel PF.

Clin Exp Immunol. 2003 Jun;132(3):485-95.

14.

Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome.

Manuelian T, Hellwage J, Meri S, Caprioli J, Noris M, Heinen S, Jozsi M, Neumann HP, Remuzzi G, Zipfel PF.

J Clin Invest. 2003 Apr;111(8):1181-90.

15.

Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family.

Kraiczy P, Hellwage J, Skerka C, Kirschfink M, Brade V, Zipfel PF, Wallich R.

Eur J Immunol. 2003 Mar;33(3):697-707.

16.

Complement C3b/C3d and cell surface polyanions are recognized by overlapping binding sites on the most carboxyl-terminal domain of complement factor H.

Hellwage J, Jokiranta TS, Friese MA, Wolk TU, Kampen E, Zipfel PF, Meri S.

J Immunol. 2002 Dec 15;169(12):6935-44.

17.

Factor H family proteins: on complement, microbes and human diseases.

Zipfel PF, Skerka C, Hellwage J, Jokiranta ST, Meri S, Brade V, Kraiczy P, Noris M, Remuzzi G.

Biochem Soc Trans. 2002 Nov;30(Pt 6):971-8. Review.

PMID:
12440956
18.

The yeast Candida albicans binds complement regulators factor H and FHL-1.

Meri T, Hartmann A, Lenk D, Eck R, Würzner R, Hellwage J, Meri S, Zipfel PF.

Infect Immun. 2002 Sep;70(9):5185-92.

19.

Onchocerca volvulus microfilariae avoid complement attack by direct binding of factor H.

Meri T, Jokiranta TS, Hellwage J, Bialonski A, Zipfel PF, Meri S.

J Infect Dis. 2002 Jun 15;185(12):1786-93. Epub 2002 May 31.

PMID:
12085326
20.
21.

Complement-regulator factor H and related proteins in otitis media with effusion.

Närkiö-Mäkelä M, Hellwage J, Tahkokallio O, Meri S.

Clin Immunol. 2001 Jul;100(1):118-26.

PMID:
11414752
22.

Complement C3b interactions studied with surface plasmon resonance technique.

Jokiranta TS, Westin J, Nilsson UR, Nilsson B, Hellwage J, Löfås S, Gordon DL, Ekdahl KN, Meri S.

Int Immunopharmacol. 2001 Mar;1(3):495-506.

PMID:
11367533
23.

The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi.

Hellwage J, Meri T, Heikkilä T, Alitalo A, Panelius J, Lahdenne P, Seppälä IJ, Meri S.

J Biol Chem. 2001 Mar 16;276(11):8427-35. Epub 2000 Dec 11.

24.

Different regulation of factor H and FHL-1/reconectin by inflammatory mediators and expression of the two proteins in rheumatoid arthritis (RA).

Friese MA, Hellwage J, Jokiranta TS, Meri S, Müller-Quernheim HJ, Peter HH, Eibel H, Zipfel PF.

Clin Exp Immunol. 2000 Aug;121(2):406-15.

25.

Each of the three binding sites on complement factor H interacts with a distinct site on C3b.

Jokiranta TS, Hellwage J, Koistinen V, Zipfel PF, Meri S.

J Biol Chem. 2000 Sep 8;275(36):27657-62.

26.

FHL-1/reconectin and factor H: two human complement regulators which are encoded by the same gene are differently expressed and regulated.

Friese MA, Hellwage J, Jokiranta TS, Meri S, Peter HH, Eibel H, Zipfel PF.

Mol Immunol. 1999 Sep-Oct;36(13-14):809-18.

PMID:
10698334
27.

Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin.

Hellwage J, Jokiranta TS, Koistinen V, Vaarala O, Meri S, Zipfel PF.

FEBS Lett. 1999 Dec 3;462(3):345-52.

29.

The factor H protein family.

Zipfel PF, Jokiranta TS, Hellwage J, Koistinen V, Meri S.

Immunopharmacology. 1999 May;42(1-3):53-60. Review.

PMID:
10408366
30.

Factor H and disease: a complement regulator affects vital body functions.

Zipfel PF, Hellwage J, Friese MA, Hegasy G, Jokiranta ST, Meri S.

Mol Immunol. 1999 Mar-Apr;36(4-5):241-8. Review.

PMID:
10403477
31.

Role of the hypervariable region in streptococcal M proteins: binding of a human complement inhibitor.

Johnsson E, Berggård K, Kotarsky H, Hellwage J, Zipfel PF, Sjöbring U, Lindahl G.

J Immunol. 1998 Nov 1;161(9):4894-901.

32.
33.

Identification of a domain in human factor H and factor H-like protein-1 required for the interaction with streptococcal M proteins.

Kotarsky H, Hellwage J, Johnsson E, Skerka C, Svensson HG, Lindahl G, Sjöbring U, Zipfel PF.

J Immunol. 1998 Apr 1;160(7):3349-54.

34.

Identification of the second heparin-binding domain in human complement factor H.

Blackmore TK, Hellwage J, Sadlon TA, Higgs N, Zipfel PF, Ward HM, Gordon DL.

J Immunol. 1998 Apr 1;160(7):3342-8.

35.

Biochemical and functional characterization of the factor-H-related protein 4 (FHR-4).

Hellwage J, Skerka C, Zipfel PF.

Immunopharmacology. 1997 Dec;38(1-2):149-57.

PMID:
9476126
36.

Expression in insect cells of the functional domain of CD21 (complement receptor type two) as a truncated soluble molecule using a baculovirus vector.

Prodinger WM, Schoch J, Schwendinger MG, Hellwage J, Parson W, Zipfel PF, Dierich MP.

Immunopharmacology. 1997 Dec;38(1-2):141-8.

PMID:
9476125
38.

The human factor H-related protein 4 (FHR-4). A novel short consensus repeat-containing protein is associated with human triglyceride-rich lipoproteins.

Skerka C, Hellwage J, Weber W, Tilkorn A, Buck F, Marti T, Kampen E, Beisiegel U, Zipfel PF.

J Biol Chem. 1997 Feb 28;272(9):5627-34.

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