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Items: 19

1.

Comparative effects of sodium channel blockers in short term rat whole embryo culture.

Nilsson MF, Sköld AC, Ericson AC, Annas A, Villar RP, Cebers G, Hellmold H, Gustafson AL, Webster WS.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):306-12. doi: 10.1016/j.taap.2013.06.023. Epub 2013 Jul 8.

PMID:
23845595
2.

Exploration of human, rat, and rabbit embryonic cardiomyocytes suggests K-channel block as a common teratogenic mechanism.

Danielsson C, Brask J, Sköld AC, Genead R, Andersson A, Andersson U, Stockling K, Pehrson R, Grinnemo KH, Salari S, Hellmold H, Danielsson B, Sylvén C, Elinder F.

Cardiovasc Res. 2013 Jan 1;97(1):23-32. doi: 10.1093/cvr/cvs296. Epub 2012 Sep 20.

PMID:
22997158
3.

Tesaglitazar, a dual PPAR-α/γ agonist, hamster carcinogenicity, investigative animal and clinical studies.

Lindblom P, Berg AL, Zhang H, Westerberg R, Tugwood J, Lundgren H, Marcusson-Ståhl M, Sjögren N, Blomgren B, Öhman P, Skånberg I, Evans J, Hellmold H.

Toxicol Pathol. 2012;40(1):18-32. doi: 10.1177/0192623311429972. Epub 2011 Nov 30.

PMID:
22131108
4.

Proliferative and molecular effects of the dual PPARalpha/gamma agonist tesaglitazar in rat adipose tissues: relevance for induction of fibrosarcoma.

Glinghammar B, Berg AL, Bjurström S, Stockling K, Blomgren B, Westerberg R, Skånberg I, Hellmold H, Andersson U.

Toxicol Pathol. 2011 Feb;39(2):325-36. doi: 10.1177/0192623310394210. Epub 2011 Jan 26.

PMID:
21270424
5.

Early stellate cell activation and veno-occlusive-disease (VOD)-like hepatotoxicity in dogs treated with AR-H047108, an imidazopyridine proton pump inhibitor.

Berg AL, Böttcher G, Andersson K, Carlsson E, Lindström AK, Huby R, Håkansson H, Skånberg-Wilhelmsson I, Hellmold H.

Toxicol Pathol. 2008 Jul;36(5):727-37. doi: 10.1177/0192623308320802. Epub 2008 Jul 22.

PMID:
18648100
6.

PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes.

Thulin P, Rafter I, Stockling K, Tomkiewicz C, Norjavaara E, Aggerbeck M, Hellmold H, Ehrenborg E, Andersson U, Cotgreave I, Glinghammar B.

Toxicol Appl Pharmacol. 2008 Aug 15;231(1):1-9. doi: 10.1016/j.taap.2008.03.007. Epub 2008 Mar 26.

PMID:
18455211
7.

Correlation network analysis for data integration and biomarker selection.

Adourian A, Jennings E, Balasubramanian R, Hines WM, Damian D, Plasterer TN, Clish CB, Stroobant P, McBurney R, Verheij ER, Bobeldijk I, van der Greef J, Lindberg J, Kenne K, Andersson U, Hellmold H, Nilsson K, Salter H, Schuppe-Koistinen I.

Mol Biosyst. 2008 Mar;4(3):249-59. doi: 10.1039/b708489g. Epub 2008 Jan 16.

PMID:
18437268
8.

Isoforms of alanine aminotransferases in human tissues and serum--differential tissue expression using novel antibodies.

Lindblom P, Rafter I, Copley C, Andersson U, Hedberg JJ, Berg AL, Samuelsson A, Hellmold H, Cotgreave I, Glinghammar B.

Arch Biochem Biophys. 2007 Oct 1;466(1):66-77. Epub 2007 Aug 11.

PMID:
17826732
9.

Tesaglitazar, a PPARalpha/gamma agonist, induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats.

Hellmold H, Zhang H, Andersson U, Blomgren B, Holland T, Berg AL, Elebring M, Sjögren N, Bamberg K, Dahl B, Westerberg R, Dillner B, Tugwood J, Tugwood J, Roberts R, Lundholm E, Camejo G, Skånberg I, Evans J.

Toxicol Sci. 2007 Jul;98(1):63-74. Epub 2007 Apr 27.

PMID:
17468185
10.

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: a microarray study.

Fletcher N, Wahlström D, Lundberg R, Nilsson CB, Nilsson KC, Stockling K, Hellmold H, Håkansson H.

Toxicol Appl Pharmacol. 2005 Aug 22;207(1):1-24.

PMID:
16054898
11.

The transcriptosomal response of human A549 lung cells to a hydrogen peroxide-generating system: relationship to DNA damage, cell cycle arrest, and caspase activation.

Dandrea T, Hellmold H, Jonsson C, Zhivotovsky B, Hofer T, Wärngård L, Cotgreave I.

Free Radic Biol Med. 2004 Apr 1;36(7):881-96.

PMID:
15019973
12.

Identification of end points relevant to detection of potentially adverse drug reactions.

Hellmold H, Nilsson CB, Schuppe-Koistinen I, Kenne K, Wärngård L.

Toxicol Lett. 2002 Feb 28;127(1-3):239-43. Review.

PMID:
12052663
13.

Identification of CYP2A3 as a major cytochrome P450 enzyme in the female peripubertal rat breast.

Hellmold H, Magnusson M, Pelto-Huikko M, Rylander T, Gustafsson J, Warner M.

Mol Pharmacol. 1998 Mar;53(3):475-82.

PMID:
9495814
14.

Characterization of cytochrome P450 enzymes in human breast tissue from reduction mammaplasties.

Hellmold H, Rylander T, Magnusson M, Reihnér E, Warner M, Gustafsson JA.

J Clin Endocrinol Metab. 1998 Mar;83(3):886-95.

PMID:
9506744
15.

Extrahepatic cytochrome P450: role in in situ toxicity and cell-specific hormone sensitivity.

Warner M, Hellmold H, Magnusson M, Rylander T, Hedlund E, Gustafsson JA.

Arch Toxicol Suppl. 1998;20:455-63.

PMID:
9442316
16.

Cytochrome P450 in the breast and brain: role in tissue-specific activation of xenobiotics.

Warner M, Hellmold H, Yoshida S, Liao D, Hedlund E, Gustafsson JA.

Mutat Res. 1997 May 12;376(1-2):79-85.

PMID:
9202741
17.

Developmental and endocrine regulation of P450 isoforms in rat breast.

Hellmold H, Lamb JG, Wyss A, Gustafsson JA, Warner M.

Mol Pharmacol. 1995 Oct;48(4):630-8.

PMID:
7476888
18.

Activation and effects of the food-derived heterocyclic amines in extrahepatic tissues.

Overvik E, Hellmold H, Branting C, Gustafsson JA.

Princess Takamatsu Symp. 1995;23:123-33. Review.

PMID:
8844803
19.

Cytochrome P450 forms in the rodent lung involved in the metabolic activation of food-derived heterocyclic amines.

Hellmold H, Overvik E, Strömstedt M, Gustafsson JA.

Carcinogenesis. 1993 Sep;14(9):1751-7.

PMID:
8403195

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