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Items: 1 to 50 of 66

1.

Eosinophils in anti-neutrophil cytoplasmic antibody associated vasculitis.

Hellmark T, Ohlsson S, Pettersson Å, Hansson M, Johansson ÅCM.

BMC Rheumatol. 2019 Mar 8;3:9. doi: 10.1186/s41927-019-0059-6. eCollection 2019.

2.

Phenotypic Characterization of Circulating CD4+ T Cells in ANCA-Associated Vasculitis.

Lilliebladh S, Johansson Å, Pettersson Å, Ohlsson S, Hellmark T.

J Immunol Res. 2018 Oct 30;2018:6984563. doi: 10.1155/2018/6984563. eCollection 2018.

3.

Anti-glomerular basement membrane disease: an update on subgroups, pathogenesis and therapies.

Segelmark M, Hellmark T.

Nephrol Dial Transplant. 2018 Oct 29. doi: 10.1093/ndt/gfy327. [Epub ahead of print]

PMID:
30371823
4.

Bone marrow eosinophils in plasma cell disorders.

Wichert S, Pettersson Å, Hellmark T, Johansson Å, Hansson M.

Exp Hematol. 2018 Oct;66:27-31.e5. doi: 10.1016/j.exphem.2018.06.288. Epub 2018 Jul 5.

PMID:
29981782
5.

Routinely used immunoassays do not detect circulating anti-GBM antibodies against native NC1 hexamer and EA epitope of the α3 chain of type IV collagen.

Clavarino G, Gauthier A, Hellmark T, Carron PL, Giovannini D, Colliard S, Dragon-Durey MA, Segelmark M, Cesbron JY, Dumestre-Pérard C.

Eur J Immunol. 2018 Jun;48(6):1082-1084. doi: 10.1002/eji.201747324. Epub 2018 May 2.

6.

Increased platelet activation occurs in cystic fibrosis patients and correlates to clinical status.

Lindberg U, Svensson L, Hellmark T, Segelmark M, Shannon O.

Thromb Res. 2018 Feb;162:32-37. doi: 10.1016/j.thromres.2017.12.012. Epub 2017 Dec 19.

PMID:
29274562
7.

Factors Associated With Pathogenicity of Anti-Glomerular Basal Membrane Antibodies: A Case Report.

Ossman R, Buob D, Hellmark T, Brocheriou I, Peltier J, Tamouza R, Dahan K, Hertig A, Rondeau E, Galichon P.

Medicine (Baltimore). 2016 May;95(19):e3654. doi: 10.1097/MD.0000000000003654.

8.

CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation?

Wuttge DM, Andreasson A, Tufvesson E, Johansson ÅC, Scheja A, Hellmark T, Hesselstrand R, Truedsson L.

Scand J Rheumatol. 2016;45(2):107-13. doi: 10.3109/03009742.2015.1054877. Epub 2015 Nov 17.

PMID:
26926492
9.

Phagocyte function decreases after high-dose treatment with melphalan and autologous stem cell transplantation in patients with multiple myeloma.

Wichert S, Pettersson Å, Hellmark T, Johansson Å, Hansson M.

Exp Hematol. 2016 May;44(5):342-351.e5. doi: 10.1016/j.exphem.2016.01.002. Epub 2016 Jan 14.

PMID:
26774385
10.

BPI-ANCA Provides Additional Clinical Information to Anti-Pseudomonas Serology: Results from a Cohort of 117 Swedish Cystic Fibrosis Patients.

Lindberg U, Carlsson M, Hellmark T, Segelmark M.

J Immunol Res. 2015;2015:947934. doi: 10.1155/2015/947934. Epub 2015 Jul 26.

11.

Increased levels of neutrophil extracellular trap remnants in the circulation of patients with small vessel vasculitis, but an inverse correlation to anti-neutrophil cytoplasmic antibodies during remission.

Söderberg D, Kurz T, Motamedi A, Hellmark T, Eriksson P, Segelmark M.

Rheumatology (Oxford). 2015 Nov;54(11):2085-94. doi: 10.1093/rheumatology/kev217. Epub 2015 Jul 12.

12.

Circulating microRNA expression pattern separates patients with anti-neutrophil cytoplasmic antibody associated vasculitis from healthy controls.

Skoglund C, Carlsen AL, Weiner M, Kurz T, Hellmark T, Eriksson P, Heegaard NH, Segelmark M.

Clin Exp Rheumatol. 2015 Mar-Apr;33(2 Suppl 89):S-64-71. Epub 2015 May 26.

PMID:
26016752
13.

Impaired phagocytosis and reactive oxygen species production in phagocytes is associated with systemic vasculitis.

Johansson ÅC, Ohlsson S, Pettersson Å, Bengtsson AA, Selga D, Hansson M, Hellmark T.

Arthritis Res Ther. 2016 Apr 22;18:92. doi: 10.1186/s13075-016-0994-1.

14.

Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus.

Bengtsson AA, Pettersson Å, Wichert S, Gullstrand B, Hansson M, Hellmark T, Johansson ÅC.

Arthritis Res Ther. 2014 Jun 5;16(3):R120. doi: 10.1186/ar4575.

15.

Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.

Ohlsson SM, Ohlsson S, Söderberg D, Gunnarsson L, Pettersson Å, Segelmark M, Hellmark T.

Clin Exp Immunol. 2014 Jun;176(3):363-72. doi: 10.1111/cei.12301.

16.

Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization.

Ohlsson SM, Linge CP, Gullstrand B, Lood C, Johansson A, Ohlsson S, Lundqvist A, Bengtsson AA, Carlsson F, Hellmark T.

Clin Immunol. 2014 May-Jun;152(1-2):10-9. doi: 10.1016/j.clim.2014.02.016. Epub 2014 Mar 12.

PMID:
24631966
17.

Diagnosis and classification of Goodpasture's disease (anti-GBM).

Hellmark T, Segelmark M.

J Autoimmun. 2014 Feb-Mar;48-49:108-12. doi: 10.1016/j.jaut.2014.01.024. Epub 2014 Jan 21. Review.

PMID:
24456936
18.

A Case of Alport Syndrome with Posttransplant Antiglomerular Basement Membrane Disease despite Negative Antiglomerular Basement Membrane Antibodies by EIA Treated with Plasmapheresis and Intravenous Immunoglobulin.

Armstead SI, Hellmark T, Wieslander J, Zhou XJ, Saxena R, Rajora N.

Case Rep Transplant. 2013;2013:164016. doi: 10.1155/2013/164016. Epub 2013 Dec 2.

19.

Circulating microRNA expression profiles associated with systemic lupus erythematosus.

Carlsen AL, Schetter AJ, Nielsen CT, Lood C, Knudsen S, Voss A, Harris CC, Hellmark T, Segelmark M, Jacobsen S, Bengtsson AA, Heegaard NH.

Arthritis Rheum. 2013 May;65(5):1324-34. doi: 10.1002/art.37890.

20.

Phagocytosis of apoptotic cells by macrophages in anti-neutrophil cytoplasmic antibody-associated systemic vasculitis.

Ohlsson SM, Pettersson Å, Ohlsson S, Selga D, Bengtsson AA, Segelmark M, Hellmark T.

Clin Exp Immunol. 2012 Oct;170(1):47-56. doi: 10.1111/j.1365-2249.2012.04633.x.

21.

Decreased neutrophil apoptosis in quiescent ANCA-associated systemic vasculitis.

Abdgawad M, Pettersson Å, Gunnarsson L, Bengtsson AA, Geborek P, Nilsson L, Segelmark M, Hellmark T.

PLoS One. 2012;7(3):e32439. doi: 10.1371/journal.pone.0032439. Epub 2012 Mar 5.

22.

Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease.

Carlsson MC, Balog CI, Kilsgård O, Hellmark T, Bakoush O, Segelmark M, Fernö M, Olsson H, Malmström J, Wuhrer M, Leffler H.

Biochim Biophys Acta. 2012 Sep;1820(9):1366-72. doi: 10.1016/j.bbagen.2012.01.007. Epub 2012 Jan 17.

PMID:
22285770
23.

Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins.

Carlsson MC, Bakoush O, Tengroth L, Kilsgård O, Malmström J, Hellmark T, Segelmark M, Leffler H.

J Clin Immunol. 2012 Apr;32(2):246-55. doi: 10.1007/s10875-011-9618-3. Epub 2011 Dec 16.

24.

Citrate treatment reduces endothelial death and inflammation under hyperglycaemic conditions.

Bryland A, Wieslander A, Carlsson O, Hellmark T, Godaly G.

Diab Vasc Dis Res. 2012 Jan;9(1):42-51. doi: 10.1177/1479164111424297. Epub 2011 Nov 1.

25.

Pseudomonas aeruginosa in cystic fibrosis: pyocyanin negative strains are associated with BPI-ANCA and progressive lung disease.

Carlsson M, Shukla S, Petersson AC, Segelmark M, Hellmark T.

J Cyst Fibros. 2011 Jul;10(4):265-71. doi: 10.1016/j.jcf.2011.03.004. Epub 2011 Apr 3.

26.

Comparison of characteristics of natural autoantibodies against myeloperoxidase and anti-myeloperoxidase autoantibodies from patients with microscopic polyangiitis.

Xu PC, Cui Z, Chen M, Hellmark T, Zhao MH.

Rheumatology (Oxford). 2011 Jul;50(7):1236-43. doi: 10.1093/rheumatology/ker085. Epub 2011 Mar 3.

PMID:
21372002
27.

Natural autoantibodies to myeloperoxidase, proteinase 3, and the glomerular basement membrane are present in normal individuals.

Cui Z, Zhao MH, Segelmark M, Hellmark T.

Kidney Int. 2010 Sep;78(6):590-7. doi: 10.1038/ki.2010.198. Epub 2010 Jun 30.

28.

Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression.

Abdgawad M, Gunnarsson L, Bengtsson AA, Geborek P, Nilsson L, Segelmark M, Hellmark T.

Clin Exp Immunol. 2010 Jul 1;161(1):89-97. doi: 10.1111/j.1365-2249.2010.04154.x. Epub 2010 May 10.

29.

IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.

van Timmeren MM, van der Veen BS, Stegeman CA, Petersen AH, Hellmark T, Collin M, Heeringa P.

J Am Soc Nephrol. 2010 Jul;21(7):1103-14. doi: 10.1681/ASN.2009090984. Epub 2010 May 6.

30.

Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes.

Yang R, Otten MA, Hellmark T, Collin M, Björck L, Zhao MH, Daha MR, Segelmark M.

Nephrol Dial Transplant. 2010 Aug;25(8):2479-86. doi: 10.1093/ndt/gfq115. Epub 2010 Mar 10.

PMID:
20219834
31.

Epitope shift of proteinase-3 anti-neutrophil cytoplasmic antibodies in patients with small vessel vasculitis.

Selga D, Segelmark M, Gunnarsson L, Hellmark T.

Clin Exp Immunol. 2010 Jun;160(3):318-24. doi: 10.1111/j.1365-2249.2009.04063.x. Epub 2010 Jan 6.

32.

Autoimmune kidney diseases.

Segelmark M, Hellmark T.

Autoimmun Rev. 2010 Mar;9(5):A366-71. doi: 10.1016/j.autrev.2009.11.007. Epub 2009 Nov 10. Review.

PMID:
19906361
33.

Neutrophil-derived proteinase 3 induces kallikrein-independent release of a novel vasoactive kinin.

Kahn R, Hellmark T, Leeb-Lundberg LM, Akbari N, Todiras M, Olofsson T, Wieslander J, Christensson A, Westman K, Bader M, Müller-Esterl W, Karpman D.

J Immunol. 2009 Jun 15;182(12):7906-15. doi: 10.4049/jimmunol.0803624.

34.

Levels of epitope-specific autoantibodies correlate with renal damage in anti-GBM disease.

Yang R, Hellmark T, Zhao J, Cui Z, Segelmark M, Zhao MH, Wang HY.

Nephrol Dial Transplant. 2009 Jun;24(6):1838-44. doi: 10.1093/ndt/gfn761. Epub 2009 Jan 16.

PMID:
19151145
35.

Identification of noncollagenous sites encoding specific interactions and quaternary assembly of alpha 3 alpha 4 alpha 5(IV) collagen: implications for Alport gene therapy.

Kang JS, Colon S, Hellmark T, Sado Y, Hudson BG, Borza DB.

J Biol Chem. 2008 Dec 12;283(50):35070-7. doi: 10.1074/jbc.M806396200. Epub 2008 Oct 16.

36.

Multicenter prospective study of the humoral autoimmune response in bullous pemphigoid.

Di Zenzo G, Thoma-Uszynski S, Fontao L, Calabresi V, Hofmann SC, Hellmark T, Sebbag N, Pedicelli C, Sera F, Lacour JP, Wieslander J, Bruckner-Tuderman L, Borradori L, Zambruno G, Hertl M.

Clin Immunol. 2008 Sep;128(3):415-26. doi: 10.1016/j.clim.2008.04.012. Epub 2008 Jun 20.

PMID:
18571472
37.

Rats and mice immunised with chimeric human/mouse proteinase 3 produce autoantibodies to mouse Pr3 and rat granulocytes.

van der Geld YM, Hellmark T, Selga D, Heeringa P, Huitema MG, Limburg PC, Kallenberg CG.

Ann Rheum Dis. 2007 Dec;66(12):1679-82. Epub 2007 Jul 20.

38.
39.

A 59-kD renal antigen as a new target for rapidly progressive glomerulonephritis.

Audard V, Hellmark T, El Karoui K, Noël LH, Pardon A, Desvaux D, Touchard G, Remy P, Lang P, Sahali D.

Am J Kidney Dis. 2007 May;49(5):710-6.

PMID:
17472855
40.

Antigen and epitope specificity of anti-glomerular basement membrane antibodies in patients with goodpasture disease with or without anti-neutrophil cytoplasmic antibodies.

Yang R, Hellmark T, Zhao J, Cui Z, Segelmark M, Zhao MH, Wang HY.

J Am Soc Nephrol. 2007 Apr;18(4):1338-43. Epub 2007 Feb 28.

41.

Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils.

Bauer S, Abdgawad M, Gunnarsson L, Segelmark M, Tapper H, Hellmark T.

J Leukoc Biol. 2007 Feb;81(2):458-64. Epub 2006 Oct 31.

PMID:
17077162
42.

A nephritogenic peptide induces intermolecular epitope spreading on collagen IV in experimental autoimmune glomerulonephritis.

Chen L, Hellmark T, Pedchenko V, Hudson BG, Pusey CD, Fox JW, Bolton WK.

J Am Soc Nephrol. 2006 Nov;17(11):3076-81. Epub 2006 Sep 27.

43.
44.

Integrin alpha3beta1, a novel receptor for alpha3(IV) noncollagenous domain and a trans-dominant Inhibitor for integrin alphavbeta3.

Borza CM, Pozzi A, Borza DB, Pedchenko V, Hellmark T, Hudson BG, Zent R.

J Biol Chem. 2006 Jul 28;281(30):20932-9. Epub 2006 May 26.

45.

Mapping of myeloperoxidase epitopes recognized by MPO-ANCA using human-mouse MPO chimers.

Erdbrügger U, Hellmark T, Bunch DO, Alcorta DA, Jennette JC, Falk RJ, Nachman PH.

Kidney Int. 2006 May;69(10):1799-805.

46.

Molecular mapping of the Goodpasture's epitope for glomerulonephritis.

Bolton WK, Chen L, Hellmark T, Fox J, Wieslander J.

Trans Am Clin Climatol Assoc. 2005;116:229-36; discussion 237-8.

47.

Epitope spreading and autoimmune glomerulonephritis in rats induced by a T cell epitope of Goodpasture's antigen.

Bolton WK, Chen L, Hellmark T, Wieslander J, Fox JW.

J Am Soc Nephrol. 2005 Sep;16(9):2657-66. Epub 2005 Jul 27.

48.

Increased monocyte transcription of the proteinase 3 gene in small vessel vasculitis.

Ohlsson S, Hellmark T, Pieters K, Sturfelt G, Wieslander J, Segelmark M.

Clin Exp Immunol. 2005 Jul;141(1):174-82.

49.
50.

Patients with Goodpasture's disease have two normal COL4A3 alleles encoding the NC1 domain of the type IV collagen alpha 3 chain.

Persson U, Hertz JM, Carlsson M, Hellmark T, Juncker I, Wieslander J, Segelmark M.

Nephrol Dial Transplant. 2004 Aug;19(8):2030-5. Epub 2004 Jun 15.

PMID:
15199166

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