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Items: 1 to 50 of 70

1.

Potash fertilizer promotes incipient salinization in groundwater irrigated semi-arid agriculture.

Buvaneshwari S, Riotte J, Sekhar M, Sharma AK, Helliwell R, Kumar MSM, Braun JJ, Ruiz L.

Sci Rep. 2020 Feb 28;10(1):3691. doi: 10.1038/s41598-020-60365-z.

2.

An Assessment of the Performance of the PLUS+ Tool in Supporting the Evaluation of Water Framework Directive Compliance in Scottish Standing Waters.

Donnelly D, Helliwell RC, May L, McCreadie B.

Int J Environ Res Public Health. 2020 Jan 7;17(2). pii: E391. doi: 10.3390/ijerph17020391.

3.

Positive allosteric modulation of P2X7 promotes apoptotic cell death over lytic cell death responses in macrophages.

Bidula S, Dhuna K, Helliwell R, Stokes L.

Cell Death Dis. 2019 Nov 25;10(12):882. doi: 10.1038/s41419-019-2110-3.

4.

Impacts of nitrogen deposition on carbon and nitrogen cycling in alpine Racomitrium heath in the UK and prospects for recovery.

Britton AJ, Gibbs S, Fisher JM, Helliwell RC.

Environ Pollut. 2019 Nov;254(Pt A):112986. doi: 10.1016/j.envpol.2019.112986. Epub 2019 Jul 31.

PMID:
31394340
5.

Dynamic Modeling and Target Loads of Sulfur and Nitrogen for Surface Waters in Finland, Norway, Sweden, and the United Kingdom.

Posch M, Aherne J, Moldan F, Evans CD, Forsius M, Larssen T, Helliwell R, Cosby BJ.

Environ Sci Technol. 2019 May 7;53(9):5062-5070. doi: 10.1021/acs.est.8b06356. Epub 2019 Apr 8.

PMID:
30924642
6.

Citizen science evidence from the past century shows that Scottish rivers are warming.

Pohle I, Helliwell R, Aube C, Gibbs S, Spencer M, Spezia L.

Sci Total Environ. 2019 Apr 1;659:53-65. doi: 10.1016/j.scitotenv.2018.12.325. Epub 2018 Dec 23.

PMID:
30594861
7.

Metabolic Control in Type 1 Diabetes: Is Adjunctive Therapy the Way Forward?

Warnes H, Helliwell R, Pearson SM, Ajjan RA.

Diabetes Ther. 2018 Oct;9(5):1831-1851. doi: 10.1007/s13300-018-0496-z. Epub 2018 Sep 12. Review.

8.

Reply to Tagliabue.

Pearce W, Hartley S, Helliwell R, O'Neill L.

EMBO Rep. 2018 Apr;19(4). pii: e45954. doi: 10.15252/embr.201845954. Epub 2018 Mar 7. No abstract available.

9.

Progressive Development of Aberrant Smooth Muscle Cell Phenotype in Abdominal Aortic Aneurysm Disease.

Riches K, Clark E, Helliwell RJ, Angelini TG, Hemmings KE, Bailey MA, Bridge KI, Scott DJA, Porter KE.

J Vasc Res. 2018;55(1):35-46. doi: 10.1159/000484088. Epub 2017 Dec 13.

10.

Why are NGOs sceptical of genome editing? NGOs' opposition to agricultural biotechnologies is rooted in scepticism about the framing of problems and solutions, rather than just emotion and dogma.

Helliwell R, Hartley S, Pearce W, O'Neill L.

EMBO Rep. 2017 Dec;18(12):2090-2093. doi: 10.15252/embr.201744385. Epub 2017 Nov 2. No abstract available.

11.

Long-term macronutrient stoichiometry of UK ombrotrophic peatlands.

Schillereff DN, Boyle JF, Toberman H, Adams JL, Bryant CL, Chiverrell RC, Helliwell RC, Keenan P, Lilly A, Tipping E.

Sci Total Environ. 2016 Dec 1;572:1561-1572. doi: 10.1016/j.scitotenv.2016.03.180. Epub 2016 Apr 17.

12.

Integrating social and value dimensions into sustainability assessment of lignocellulosic biofuels.

Raman S, Mohr A, Helliwell R, Ribeiro B, Shortall O, Smith R, Millar K.

Biomass Bioenergy. 2015 Nov;82:49-62.

13.

Aged riverine particulate organic carbon in four UK catchments.

Adams JL, Tipping E, Bryant CL, Helliwell RC, Toberman H, Quinton J.

Sci Total Environ. 2015 Dec 1;536:648-654. doi: 10.1016/j.scitotenv.2015.06.141. Epub 2015 Aug 4.

PMID:
26254066
14.

Selected ginsenosides of the protopanaxdiol series are novel positive allosteric modulators of P2X7 receptors.

Helliwell RM, ShioukHuey CO, Dhuna K, Molero JC, Ye JM, Xue CC, Stokes L.

Br J Pharmacol. 2015 Jul;172(13):3326-40. doi: 10.1111/bph.13123. Epub 2015 Apr 24.

15.

Therapeutic potential of Panax ginseng and ginsenosides in the treatment of chronic obstructive pulmonary disease.

Shergis JL, Di YM, Zhang AL, Vlahos R, Helliwell R, Ye JM, Xue CC.

Complement Ther Med. 2014 Oct;22(5):944-53. doi: 10.1016/j.ctim.2014.08.006. Epub 2014 Aug 20. Review.

PMID:
25440386
16.

Assessing recovery from acidification of European surface waters in the year 2010: evaluation of projections made with the MAGIC model in 1995.

Helliwell RC, Wright RF, Jackson-Blake LA, Ferrier RC, Aherne J, Cosby BJ, Evans CD, Forsius M, Hruska J, Jenkins A, Kram P, Kopáček J, Majer V, Moldan F, Posch M, Potts JM, Rogora M, Schöpp W.

Environ Sci Technol. 2014 Nov 18;48(22):13280-8. doi: 10.1021/es502533c. Epub 2014 Nov 3.

17.

Atmospheric deposition of phosphorus to land and freshwater.

Tipping E, Benham S, Boyle JF, Crow P, Davies J, Fischer U, Guyatt H, Helliwell R, Jackson-Blake L, Lawlor AJ, Monteith DT, Rowe EC, Toberman H.

Environ Sci Process Impacts. 2014 Jul;16(7):1608-17. doi: 10.1039/c3em00641g.

PMID:
24526176
18.

An in vitro study of neuroprotective properties of traditional Chinese herbal medicines thought to promote healthy ageing and longevity.

Shen B, Truong J, Helliwell R, Govindaraghavan S, Sucher NJ.

BMC Complement Altern Med. 2013 Dec 27;13:373. doi: 10.1186/1472-6882-13-373.

19.

Controls on soil solution nitrogen along an altitudinal gradient in the Scottish uplands.

Jackson-Blake L, Helliwell RC, Britton AJ, Gibbs S, Coull MC, Dawson L.

Sci Total Environ. 2012 Aug 1;431:100-8. doi: 10.1016/j.scitotenv.2012.05.019. Epub 2012 Jun 4.

PMID:
22673176
20.

Drought alters carbon fluxes in alpine snowbed ecosystems through contrasting impacts on graminoids and forbs.

Johnson D, Vachon J, Britton AJ, Helliwell RC.

New Phytol. 2011 May;190(3):740-9. doi: 10.1111/j.1469-8137.2010.03613.x. Epub 2011 Jan 19.

21.

The present is the key to the past, but what does the future hold for the recovery of surface waters from acidification?

Helliwell RC, Simpson GL.

Water Res. 2010 May;44(10):3166-80. doi: 10.1016/j.watres.2010.02.030. Epub 2010 Feb 24.

PMID:
20227743
22.

In vitro profiling against ion channels beyond hERG as an early indicator of cardiac risk.

Chen MX, Helliwell RM, Clare JJ.

Curr Opin Mol Ther. 2009 Jun;11(3):269-81.

PMID:
19479660
23.

Recording hERG potassium currents and assessing the effects of compounds using the whole-cell patch-clamp technique.

Helliwell RM.

Methods Mol Biol. 2008;491:279-95. doi: 10.1007/978-1-59745-526-8_22.

PMID:
18998101
24.

Interactive effects of nitrogen deposition and fire on plant and soil chemistry in an alpine heathland.

Britton AJ, Helliwell RC, Fisher JM, Gibbs S.

Environ Pollut. 2008 Nov;156(2):409-16. doi: 10.1016/j.envpol.2008.01.029. Epub 2008 Mar 5.

PMID:
18325647
25.

Regional specificity of magnetic resonance imaging and histopathology following cerebral ischemia in preterm fetal sheep.

Fraser M, Bennet L, Helliwell R, Wells S, Williams C, Gluckman P, Gunn AJ, Inder T.

Reprod Sci. 2007 Feb;14(2):182-91.

PMID:
17636230
26.

Modelling the effect of climate change on recovery of acidified freshwaters: relative sensitivity of individual processes in the MAGIC model.

Wright RF, Aherne J, Bishop K, Camarero L, Cosby BJ, Erlandsson M, Evans CD, Forsius M, Hardekopf DW, Helliwell R, Hruska J, Jenkins A, Kopácek J, Moldan F, Posch M, Rogora M.

Sci Total Environ. 2006 Jul 15;365(1-3):154-66. Epub 2006 Apr 17.

PMID:
16616318
27.

Gestational age-dependent up-regulation of prostaglandin D synthase (PGDS) and production of PGDS-derived antiinflammatory prostaglandins in human placenta.

Helliwell RJ, Keelan JA, Marvin KW, Adams L, Chang MC, Anand A, Sato TA, O'Carroll S, Chaiworapongsa T, Romero RJ, Mitchell MD.

J Clin Endocrinol Metab. 2006 Feb;91(2):597-606. Epub 2005 Nov 15.

PMID:
16291703
28.

Nitrate leaching as a confounding factor in chemical recovery from acidification in UK upland waters.

Curtis CJ, Evans CD, Helliwell RC, Monteith DT.

Environ Pollut. 2005 Sep;137(1):73-82.

PMID:
15944041
29.

Identification of 9alpha,11beta-prostaglandin F2 in human amniotic fluid and characterization of its production by human gestational tissues.

Mitchell MD, Chang MC, Chaiworapongsa T, Lan HY, Helliwell RJ, Romero R, Sato TA.

J Clin Endocrinol Metab. 2005 Jul;90(7):4244-8. Epub 2005 Apr 19.

PMID:
15840748
31.

Recovery of acidified European surface waters.

Wright RF, Larssen T, Camarero L, Cosby BJ, Ferrier RC, Helliwell R, Forsius M, Jenkins A, Kopácek J, Majer V, Moldan F, Posch M, Rogora M, Schöpp W.

Environ Sci Technol. 2005 Feb 1;39(3):64A-72A. Review. No abstract available.

PMID:
15757325
32.

Characterization of the endocannabinoid system in early human pregnancy.

Helliwell RJ, Chamley LW, Blake-Palmer K, Mitchell MD, Wu J, Kearn CS, Glass M.

J Clin Endocrinol Metab. 2004 Oct;89(10):5168-74.

PMID:
15472222
33.

Structural determinants of HERG channel block by clofilium and ibutilide.

Perry M, de Groot MJ, Helliwell R, Leishman D, Tristani-Firouzi M, Sanguinetti MC, Mitcheson J.

Mol Pharmacol. 2004 Aug;66(2):240-9.

PMID:
15266014
34.

Differential effects of serum constituents on apoptosis induced by the cyclopentenone prostaglandin 15-deoxy-delta12,14-prostaglandin J2 in WISH epithelial cells.

Berry EB, Sato TA, Mitchell MD, Stewart Gilmour R, Helliwell RJ.

Prostaglandins Leukot Essent Fatty Acids. 2004 Sep;71(3):191-7.

PMID:
15253890
35.

Will reduced sulphur emissions under the Second Sulphur Protocol lead to recovery of acid sensitive sites in UK?

Jenkins A, Helliwell RC, Swingewood PJ, Sefton C, Renshaw M, Ferrier RC.

Environ Pollut. 1998;99(3):309-18.

PMID:
15093295
36.

Nuclear prostaglandin receptors: role in pregnancy and parturition?

Helliwell RJ, Berry EB, O'Carroll SJ, Mitchell MD.

Prostaglandins Leukot Essent Fatty Acids. 2004 Feb;70(2):149-65. Review.

PMID:
14683690
37.

Prostaglandin synthases: recent developments and a novel hypothesis.

Helliwell RJ, Adams LF, Mitchell MD.

Prostaglandins Leukot Essent Fatty Acids. 2004 Feb;70(2):101-13. Review.

PMID:
14683687
38.

Peroxisome proliferator-activated receptor isoform expression changes in human gestational tissues with labor at term.

Berry EB, Eykholt R, Helliwell RJ, Gilmour RS, Mitchell MD, Marvin KW.

Mol Pharmacol. 2003 Dec;64(6):1586-90.

PMID:
14645690
39.

3'-azido-3'-deoxythymidine (AZT) induces apoptosis and alters metabolic enzyme activity in human placenta.

Collier AC, Helliwell RJ, Keelan JA, Paxton JW, Mitchell MD, Tingle MD.

Toxicol Appl Pharmacol. 2003 Oct 15;192(2):164-73.

PMID:
14550750
40.

Traumatic pseudoaneurysms of the superficial temporal artery.

Cadamy AJ, McNaughton GW, Helliwell R.

Eur J Emerg Med. 2003 Sep;10(3):236-7.

PMID:
12972903
41.

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), TRAIL receptors, and the soluble receptor osteoprotegerin in human gestational membranes and amniotic fluid during pregnancy and labor at term and preterm.

Lonergan M, Aponso D, Marvin KW, Helliwell RJ, Sato TA, Mitchell MD, Chaiwaropongsa T, Romero R, Keelan JA.

J Clin Endocrinol Metab. 2003 Aug;88(8):3835-44.

PMID:
12915677
42.

Cytokines, prostaglandins and parturition--a review.

Keelan JA, Blumenstein M, Helliwell RJ, Sato TA, Marvin KW, Mitchell MD.

Placenta. 2003 Apr;24 Suppl A:S33-46. Review.

PMID:
12842412
43.

Water quality in the Scottish uplands: a hydrological perspective on catchment hydrochemistry.

Soulsby C, Gibbins C, Wade AJ, Smart R, Helliwell R.

Sci Total Environ. 2002 Jul 22;294(1-3):73-94.

PMID:
12169013
44.

15-deoxy-delta12,14-prostaglandin J2-induced apoptosis in amnion-like WISH cells.

Keelan J, Helliwell R, Nijmeijer B, Berry E, Sato T, Marvin K, Mitchell M, Gilmour R.

Prostaglandins Other Lipid Mediat. 2001 Dec;66(4):265-82.

PMID:
11785780
45.

Interaction of nitrogen deposition and land use on soil and water quality in Scotland: issues of spatial variability and scale.

Helliwell RC, Ferrier RC, Kernan MR.

Sci Total Environ. 2001 Jan 29;265(1-3):51-63.

PMID:
11227282
47.

Glial cell line derived neurotrophic factor (GDNF) regulates VR1 and substance P in cultured sensory neurons.

Ogun-Muyiwa P, Helliwell R, McIntyre P, Winter J.

Neuroreport. 1999 Jul 13;10(10):2107-11.

PMID:
10424683
48.
49.

Capsaicin sensitivity is associated with the expression of the vanilloid (capsaicin) receptor (VR1) mRNA in adult rat sensory ganglia.

Helliwell RJ, McLatchie LM, Clarke M, Winter J, Bevan S, McIntyre P.

Neurosci Lett. 1998 Jul 10;250(3):177-80.

PMID:
9708861
50.

Contrasting expression of KAL in cell-free systems: 5' UTR and coding region structural effects on translation.

de Zoysa PA, Helliwell RJ, Duke VM, Quinton R, Bouloux PM.

Protein Expr Purif. 1998 Jul;13(2):235-42.

PMID:
9675068

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