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Items: 1 to 50 of 279

1.

Exploiting Day- and Night-Time Metabolism of Synechocystis sp. PCC 6803 for Fitness-Coupled Fumarate Production around the Clock.

Du W, Jongbloets JA, Guillaume M, van de Putte B, Battaglino B, Hellingwerf KJ, Branco Dos Santos F.

ACS Synth Biol. 2019 Oct 18;8(10):2263-2269. doi: 10.1021/acssynbio.9b00289. Epub 2019 Oct 1.

PMID:
31553573
2.

Functional Expression of Gloeobacter Rhodopsin in PSI-Less Synechocystis sp. PCC6803.

Chen Q, Arents J, Schuurmans JM, Ganapathy S, de Grip WJ, Cheregi O, Funk C, Branco Dos Santos F, Hellingwerf KJ.

Front Bioeng Biotechnol. 2019 Mar 29;7:67. doi: 10.3389/fbioe.2019.00067. eCollection 2019.

3.

Redshifted and Near-infrared Active Analog Pigments Based upon Archaerhodopsin-3.

Ganapathy S, Kratz S, Chen Q, Hellingwerf KJ, de Groot HJM, Rothschild KJ, de Grip WJ.

Photochem Photobiol. 2019 Jul;95(4):959-968. doi: 10.1111/php.13093. Epub 2019 Apr 8.

PMID:
30860604
4.

On the use of oxygenic photosynthesis for the sustainable production of commodity chemicals.

Pérez AA, Chen Q, Hernández HP, Branco Dos Santos F, Hellingwerf KJ.

Physiol Plant. 2019 May;166(1):413-427. doi: 10.1111/ppl.12946. Epub 2019 Mar 26.

PMID:
30829400
5.

Exploring the low photosynthetic efficiency of cyanobacteria in blue light using a mutant lacking phycobilisomes.

Luimstra VM, Schuurmans JM, de Carvalho CFM, Matthijs HCP, Hellingwerf KJ, Huisman J.

Photosynth Res. 2019 Sep;141(3):291-301. doi: 10.1007/s11120-019-00630-z. Epub 2019 Feb 28.

6.

Combining retinal-based and chlorophyll-based (oxygenic) photosynthesis: Proteorhodopsin expression increases growth rate and fitness of a ∆PSI strain of Synechocystis sp. PCC6803.

Chen Q, Arents J, Schuurmans JM, Ganapathy S, de Grip WJ, Cheregi O, Funk C, Dos Santos FB, Hellingwerf KJ.

Metab Eng. 2019 Mar;52:68-76. doi: 10.1016/j.ymben.2018.11.002. Epub 2018 Nov 14.

PMID:
30447329
7.

Response of the thylakoid proteome of Synechocystis sp. PCC 6803 to photohinibitory intensities of orange-red light.

Cordara A, Manfredi M, van Alphen P, Marengo E, Pirone R, Saracco G, Branco Dos Santos F, Hellingwerf KJ, Pagliano C.

Plant Physiol Biochem. 2018 Nov;132:524-534. doi: 10.1016/j.plaphy.2018.10.002. Epub 2018 Oct 5.

PMID:
30316162
8.

Challenges in the Application of Synthetic Biology Toward Synthesis of Commodity Products by Cyanobacteria via "Direct Conversion".

Du W, Burbano PC, Hellingwerf KJ, Branco Dos Santos F.

Adv Exp Med Biol. 2018;1080:3-26. doi: 10.1007/978-981-13-0854-3_1. Review.

PMID:
30091089
9.

Blue light reduces photosynthetic efficiency of cyanobacteria through an imbalance between photosystems I and II.

Luimstra VM, Schuurmans JM, Verschoor AM, Hellingwerf KJ, Huisman J, Matthijs HCP.

Photosynth Res. 2018 Nov;138(2):177-189. doi: 10.1007/s11120-018-0561-5. Epub 2018 Jul 19.

10.
11.

Spectrally decomposed dark-to-light transitions in Synechocystis sp. PCC 6803.

Acuña AM, van Alphen P, Branco Dos Santos F, van Grondelle R, Hellingwerf KJ, van Stokkum IHM.

Photosynth Res. 2018 Aug;137(2):307-320. doi: 10.1007/s11120-018-0505-0. Epub 2018 Mar 29.

PMID:
29600442
12.

Increasing the Photoautotrophic Growth Rate of Synechocystis sp. PCC 6803 by Identifying the Limitations of Its Cultivation.

van Alphen P, Abedini Najafabadi H, Branco Dos Santos F, Hellingwerf KJ.

Biotechnol J. 2018 Aug;13(8):e1700764. doi: 10.1002/biot.201700764. Epub 2018 May 2.

PMID:
29577667
13.

Deletion of sll1541 in Synechocystis sp. Strain PCC 6803 Allows Formation of a Far-Red-Shifted holo-Proteorhodopsin In Vivo.

Chen Q, van der Steen JB, Arents JC, Hartog AF, Ganapathy S, de Grip WJ, Hellingwerf KJ.

Appl Environ Microbiol. 2018 Apr 16;84(9). pii: e02435-17. doi: 10.1128/AEM.02435-17. Print 2018 May 1.

14.

Alignment of microbial fitness with engineered product formation: obligatory coupling between acetate production and photoautotrophic growth.

Du W, Jongbloets JA, van Boxtel C, Pineda Hernández H, Lips D, Oliver BG, Hellingwerf KJ, Branco Dos Santos F.

Biotechnol Biofuels. 2018 Feb 13;11:38. doi: 10.1186/s13068-018-1037-8. eCollection 2018.

15.

Spectrally decomposed dark-to-light transitions in a PSI-deficient mutant of Synechocystis sp. PCC 6803.

Acuña AM, van Alphen P, Branco Dos Santos F, van Grondelle R, Hellingwerf KJ, van Stokkum IHM.

Biochim Biophys Acta Bioenerg. 2018 Feb;1859(2):57-68. doi: 10.1016/j.bbabio.2017.11.002. Epub 2017 Nov 11.

16.

Functional Expression of Gloeobacter Rhodopsin in Synechocystis sp. PCC6803.

Chen Q, Arents J, Ganapathy S, de Grip WJ, Hellingwerf KJ.

Photochem Photobiol. 2017 May;93(3):772-781. doi: 10.1111/php.12745.

PMID:
28500716
17.

Ethylene production with engineered Synechocystis sp PCC 6803 strains.

Veetil VP, Angermayr SA, Hellingwerf KJ.

Microb Cell Fact. 2017 Feb 23;16(1):34. doi: 10.1186/s12934-017-0645-5.

18.

Transition from exponential to linear photoautotrophic growth changes the physiology of Synechocystis sp. PCC 6803.

Schuurmans RM, Matthijs JC, Hellingwerf KJ.

Photosynth Res. 2017 Apr;132(1):69-82. doi: 10.1007/s11120-016-0329-8. Epub 2017 Jan 20.

19.

Retinal-Based Proton Pumping in the Near Infrared.

Ganapathy S, Venselaar H, Chen Q, de Groot HJ, Hellingwerf KJ, de Grip WJ.

J Am Chem Soc. 2017 Feb 15;139(6):2338-2344. doi: 10.1021/jacs.6b11366. Epub 2017 Feb 2.

20.

Nonhierarchical Flux Regulation Exposes the Fitness Burden Associated with Lactate Production in Synechocystis sp. PCC6803.

Du W, Angermayr SA, Jongbloets JA, Molenaar D, Bachmann H, Hellingwerf KJ, Branco Dos Santos F.

ACS Synth Biol. 2017 Mar 17;6(3):395-401. doi: 10.1021/acssynbio.6b00235. Epub 2016 Dec 12.

PMID:
27936615
21.

All Three Endogenous Quinone Species of Escherichia coli Are Involved in Controlling the Activity of the Aerobic/Anaerobic Response Regulator ArcA.

van Beilen JW, Hellingwerf KJ.

Front Microbiol. 2016 Sep 7;7:1339. doi: 10.3389/fmicb.2016.01339. eCollection 2016.

22.

Slr1670 from Synechocystis sp. PCC 6803 Is Required for the Re-assimilation of the Osmolyte Glucosylglycerol.

Savakis P, Tan X, Qiao C, Song K, Lu X, Hellingwerf KJ, Branco Dos Santos F.

Front Microbiol. 2016 Aug 29;7:1350. doi: 10.3389/fmicb.2016.01350. eCollection 2016.

23.

Culturing Synechocystis sp. Strain PCC 6803 with N2 and CO2 in a Diel Regime Reveals Multiphase Glycogen Dynamics with Low Maintenance Costs.

Angermayr SA, van Alphen P, Hasdemir D, Kramer G, Iqbal M, van Grondelle W, Hoefsloot HC, Choi YH, Hellingwerf KJ.

Appl Environ Microbiol. 2016 Jun 30;82(14):4180-4189. doi: 10.1128/AEM.00256-16. Print 2016 Jul 15.

24.

Photochemical Reactions of the LOV and LOV-Linker Domains of the Blue Light Sensor Protein YtvA.

Choi S, Nakasone Y, Hellingwerf KJ, Terazima M.

Biochemistry. 2016 Jun 7;55(22):3107-15. doi: 10.1021/acs.biochem.6b00263. Epub 2016 May 27.

PMID:
27203230
25.

Corrigendum: Synechocystis: not just a plug-bug for CO2, but a green E. coli.

Branco Dos Santos F, Du W, Hellingwerf KJ.

Front Bioeng Biotechnol. 2016 Apr 13;4:32. doi: 10.3389/fbioe.2016.00032. eCollection 2016.

26.

Genetic engineering of Synechocystis PCC6803 for the photoautotrophic production of the sweetener erythritol.

van der Woude AD, Perez Gallego R, Vreugdenhil A, Puthan Veetil V, Chroumpi T, Hellingwerf KJ.

Microb Cell Fact. 2016 Apr 8;15:60. doi: 10.1186/s12934-016-0458-y.

27.

Carbon Monoxide Gas Is Not Inert, but Global, in Its Consequences for Bacterial Gene Expression, Iron Acquisition, and Antibiotic Resistance.

Wareham LK, Begg R, Jesse HE, Van Beilen JW, Ali S, Svistunenko D, McLean S, Hellingwerf KJ, Sanguinetti G, Poole RK.

Antioxid Redox Signal. 2016 Jun 10;24(17):1013-28. doi: 10.1089/ars.2015.6501. Epub 2016 Mar 30.

28.

Expression of holo-proteorhodopsin in Synechocystis sp. PCC 6803.

Chen Q, van der Steen JB, Dekker HL, Ganapathy S, de Grip WJ, Hellingwerf KJ.

Metab Eng. 2016 May;35:83-94. doi: 10.1016/j.ymben.2016.02.001. Epub 2016 Feb 8.

PMID:
26869136
29.

Chirality Matters: Synthesis and Consumption of the d-Enantiomer of Lactic Acid by Synechocystis sp. Strain PCC6803.

Angermayr SA, van der Woude AD, Correddu D, Kern R, Hagemann M, Hellingwerf KJ.

Appl Environ Microbiol. 2015 Dec 18;82(4):1295-1304. doi: 10.1128/AEM.03379-15. Print 2016 Feb 15.

30.

Single-cell screening of photosynthetic growth and lactate production by cyanobacteria.

Hammar P, Angermayr SA, Sjostrom SL, van der Meer J, Hellingwerf KJ, Hudson EP, Joensson HN.

Biotechnol Biofuels. 2015 Nov 25;8:193. doi: 10.1186/s13068-015-0380-2. eCollection 2015.

31.

Comparison of the Photosynthetic Yield of Cyanobacteria and Green Algae: Different Methods Give Different Answers.

Schuurmans RM, van Alphen P, Schuurmans JM, Matthijs HC, Hellingwerf KJ.

PLoS One. 2015 Sep 22;10(9):e0139061. doi: 10.1371/journal.pone.0139061. eCollection 2015.

32.

Quantitative proteomics analysis of an ethanol- and a lactate-producing mutant strain of Synechocystis sp. PCC6803.

Borirak O, de Koning LJ, van der Woude AD, Hoefsloot HC, Dekker HL, Roseboom W, de Koster CG, Hellingwerf KJ.

Biotechnol Biofuels. 2015 Aug 5;8:111. doi: 10.1186/s13068-015-0294-z. eCollection 2015.

33.

Activation of the General Stress Response of Bacillus subtilis by Visible Light.

van der Steen JB, Hellingwerf KJ.

Photochem Photobiol. 2015 Sep-Oct;91(5):1032-45. doi: 10.1111/php.12499. Epub 2015 Aug 11. Review.

PMID:
26189730
34.

Photoreceptors in Chemotrophic Prokaryotes: The Case of Acinetobacter spp. Revisited.

Nudel CB, Hellingwerf KJ.

Photochem Photobiol. 2015 Sep-Oct;91(5):1012-20. doi: 10.1111/php.12491. Epub 2015 Aug 8. Review.

PMID:
26147719
35.

Time-series analysis of the transcriptome and proteome of Escherichia coli upon glucose repression.

Borirak O, Rolfe MD, de Koning LJ, Hoefsloot HC, Bekker M, Dekker HL, Roseboom W, Green J, de Koster CG, Hellingwerf KJ.

Biochim Biophys Acta. 2015 Oct;1854(10 Pt A):1269-79. doi: 10.1016/j.bbapap.2015.05.017. Epub 2015 Jun 4.

36.

Sustained Circadian Rhythms in Continuous Light in Synechocystis sp. PCC6803 Growing in a Well-Controlled Photobioreactor.

van Alphen P, Hellingwerf KJ.

PLoS One. 2015 Jun 1;10(6):e0127715. doi: 10.1371/journal.pone.0127715. eCollection 2015.

37.

Metabolic engineering of cyanobacteria for the synthesis of commodity products.

Angermayr SA, Gorchs Rovira A, Hellingwerf KJ.

Trends Biotechnol. 2015 Jun;33(6):352-61. doi: 10.1016/j.tibtech.2015.03.009. Epub 2015 Apr 21. Review.

PMID:
25908503
38.

Modulation of spectral properties and pump activity of proteorhodopsins by retinal analogues.

Ganapathy S, Bécheau O, Venselaar H, Frölich S, van der Steen JB, Chen Q, Radwan S, Lugtenburg J, Hellingwerf KJ, de Groot HJ, de Grip WJ.

Biochem J. 2015 Apr 15;467(2):333-43. doi: 10.1042/BJ20141210.

PMID:
25655771
39.

Photosynthetic production of glycerol by a recombinant cyanobacterium.

Savakis P, Tan X, Du W, Branco dos Santos F, Lu X, Hellingwerf KJ.

J Biotechnol. 2015 Feb 10;195:46-51. doi: 10.1016/j.jbiotec.2014.12.015. Epub 2014 Dec 23.

PMID:
25541461
40.

Engineering cyanobacteria for direct biofuel production from CO2.

Savakis P, Hellingwerf KJ.

Curr Opin Biotechnol. 2015 Jun;33:8-14. doi: 10.1016/j.copbio.2014.09.007. Epub 2014 Oct 8. Review.

PMID:
25305544
41.

Synechocystis: Not Just a Plug-Bug for CO2, but a Green E. coli.

Branco Dos Santos F, Du W, Hellingwerf KJ.

Front Bioeng Biotechnol. 2014 Sep 18;2:36. doi: 10.3389/fbioe.2014.00036. eCollection 2014. Review. Erratum in: Front Bioeng Biotechnol. 2016;4:32.

42.

Short hydrogen bonds and negative charge in photoactive yellow protein promote fast isomerization but not high quantum yield.

Zhu J, Vreede J, Hospes M, Arents J, Kennis JT, van Stokkum IH, Hellingwerf KJ, Groot ML.

J Phys Chem B. 2015 Feb 12;119(6):2372-83. doi: 10.1021/jp506785q. Epub 2014 Aug 29.

PMID:
25144816
43.

Distinct effects of sorbic acid and acetic acid on the electrophysiology and metabolism of Bacillus subtilis.

van Beilen JW, Teixeira de Mattos MJ, Hellingwerf KJ, Brul S.

Appl Environ Microbiol. 2014 Oct;80(19):5918-26. doi: 10.1128/AEM.01391-14. Epub 2014 Jul 18.

44.

Exploring metabolic engineering design principles for the photosynthetic production of lactic acid by Synechocystis sp. PCC6803.

Angermayr SA, van der Woude AD, Correddu D, Vreugdenhil A, Verrone V, Hellingwerf KJ.

Biotechnol Biofuels. 2014 Jun 26;7:99. doi: 10.1186/1754-6834-7-99. eCollection 2014.

45.

Carbon sink removal: Increased photosynthetic production of lactic acid by Synechocystis sp. PCC6803 in a glycogen storage mutant.

van der Woude AD, Angermayr SA, Puthan Veetil V, Osnato A, Hellingwerf KJ.

J Biotechnol. 2014 Aug 20;184:100-2. doi: 10.1016/j.jbiotec.2014.04.029. Epub 2014 May 21.

PMID:
24858679
46.

Towards a systems level understanding of the oxygen response of Escherichia coli.

Bettenbrock K, Bai H, Ederer M, Green J, Hellingwerf KJ, Holcombe M, Kunz S, Rolfe MD, Sanguinetti G, Sawodny O, Sharma P, Steinsiek S, Poole RK.

Adv Microb Physiol. 2014;64:65-114. doi: 10.1016/B978-0-12-800143-1.00002-6. Review.

PMID:
24797925
47.

On the in vivo redox state of flavin-containing photosensory receptor proteins.

Bury A, Hellingwerf KJ.

Methods Mol Biol. 2014;1146:177-90. doi: 10.1007/978-1-4939-0452-5_9.

PMID:
24764093
48.

The redox potential of the plastoquinone pool of the cyanobacterium Synechocystis species strain PCC 6803 is under strict homeostatic control.

Schuurmans RM, Schuurmans JM, Bekker M, Kromkamp JC, Matthijs HC, Hellingwerf KJ.

Plant Physiol. 2014 May;165(1):463-75. doi: 10.1104/pp.114.237313. Epub 2014 Apr 2.

49.

A kinetic model of catabolic adaptation and protein reprofiling in Saccharomyces cerevisiae during temperature shifts.

Mensonides FI, Brul S, Hellingwerf KJ, Bakker BM, Teixeira de Mattos MJ.

FEBS J. 2014 Feb;281(3):825-41.

PMID:
24616920
50.

Molecular physiology of the dynamic regulation of carbon catabolite repression in Escherichia coli.

Borirak O, Bekker M, Hellingwerf KJ.

Microbiology. 2014 Jun;160(Pt 6):1214-23. doi: 10.1099/mic.0.077289-0. Epub 2014 Mar 6.

PMID:
24603062

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