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Items: 1 to 50 of 196

1.

Racial differences in in vivo adipose lipid kinetics in humans.

White UA, Fitch MD, Beyl RA, Hellerstein MK, Ravussin E.

J Lipid Res. 2018 Jun 17. pii: jlr.P082628. doi: 10.1194/jlr.P082628. [Epub ahead of print]

2.

Dilution of oral D3 -Creatine to measure creatine pool size and estimate skeletal muscle mass: development of a correction algorithm.

Shankaran M, Czerwieniec G, Fessler C, Wong PA, Killion S, Turner SM, Hellerstein MK, Evans WJ.

J Cachexia Sarcopenia Muscle. 2018 Jun;9(3):540-546. doi: 10.1002/jcsm.12278. Epub 2018 Apr 16.

3.

Dose-dependent quantitative effects of acute fructose administration on hepatic de novo lipogenesis in healthy humans.

Beysen C, Ruddy M, Stoch A, Mixson L, Rosko K, Riiff T, Turner SM, Hellerstein MK, Murphy EJ.

Am J Physiol Endocrinol Metab. 2018 Jul 1;315(1):E126-E132. doi: 10.1152/ajpendo.00470.2017. Epub 2018 Mar 20.

PMID:
29558206
4.

A Randomized Controlled Trial of Lisinopril to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Individuals.

Cockerham LR, Yukl SA, Harvill K, Somsouk M, Joshi SK, Sinclair E, Liegler T, Hoh R, Lyons S, Hunt PW, Rupert A, Sereti I, Morcock DR, Rhodes A, Emson C, Hellerstein MK, Estes JD, Lewin S, Deeks SG, Hatano H.

Pathog Immun. 2017;2(3):310-334. doi: 10.20411/pai.v2i3.207. Epub 2017 Aug 2.

5.

Association of In Vivo Adipose Tissue Cellular Kinetics With Markers of Metabolic Health in Humans.

White UA, Fitch MD, Beyl RA, Hellerstein MK, Ravussin E.

J Clin Endocrinol Metab. 2017 Jul 1;102(7):2171-2178. doi: 10.1210/jc.2016-4000.

6.

Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib.

Burger JA, Li KW, Keating MJ, Sivina M, Amer AM, Garg N, Ferrajoli A, Huang X, Kantarjian H, Wierda WG, O'Brien S, Hellerstein MK, Turner SM, Emson CL, Chen SS, Yan XJ, Wodarz D, Chiorazzi N.

JCI Insight. 2017 Jan 26;2(2):e89904. doi: 10.1172/jci.insight.89904.

7.

A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism.

Fisher FM, Kim M, Doridot L, Cunniff JC, Parker TS, Levine DM, Hellerstein MK, Hudgins LC, Maratos-Flier E, Herman MA.

Mol Metab. 2016 Nov 23;6(1):14-21. doi: 10.1016/j.molmet.2016.11.008. eCollection 2017 Jan.

8.

Leukemia-cell proliferation and disease progression in patients with early stage chronic lymphocytic leukemia.

Murphy EJ, Neuberg DS, Rassenti LZ, Hayes G, Redd R, Emson C, Li K, Brown JR, Wierda WG, Turner S, Greaves AW, Zent CS, Byrd JC, McConnel C, Barrientos J, Kay N, Hellerstein MK, Chiorazzi N, Kipps TJ, Rai KR.

Leukemia. 2017 Jun;31(6):1348-1354. doi: 10.1038/leu.2017.34. Epub 2017 Jan 24.

9.

Identifying nonalcoholic fatty liver disease patients with active fibrosis by measuring extracellular matrix remodeling rates in tissue and blood.

Decaris ML, Li KW, Emson CL, Gatmaitan M, Liu S, Wang Y, Nyangau E, Colangelo M, Angel TE, Beysen C, Cui J, Hernandez C, Lazaro L, Brenner DA, Turner SM, Hellerstein MK, Loomba R.

Hepatology. 2017 Jan;65(1):78-88. doi: 10.1002/hep.28860. Epub 2016 Nov 15.

10.

Differences in In Vivo Cellular Kinetics in Abdominal and Femoral Subcutaneous Adipose Tissue in Women.

White UA, Fitch MD, Beyl RA, Hellerstein MK, Ravussin E.

Diabetes. 2016 Jun;65(6):1642-7. doi: 10.2337/db15-1617. Epub 2016 Mar 18.

11.

Isocaloric manipulation of macronutrients within a high-carbohydrate/moderate-fat diet induces unique effects on hepatic lipogenesis, steatosis and liver injury.

Pierce AA, Duwaerts CC, Soon RK, Siao K, Grenert JP, Fitch M, Hellerstein MK, Beysen C, Turner SM, Maher JJ.

J Nutr Biochem. 2016 Mar;29:12-20. doi: 10.1016/j.jnutbio.2015.10.020. Epub 2015 Nov 17.

12.

Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats.

Shankaran M, Shearer TW, Stimpson SA, Turner SM, King C, Wong PY, Shen Y, Turnbull PS, Kramer F, Clifton L, Russell A, Hellerstein MK, Evans WJ.

Am J Physiol Endocrinol Metab. 2016 Mar 15;310(6):E405-17. doi: 10.1152/ajpendo.00257.2015. Epub 2015 Dec 29.

13.

Circulating protein synthesis rates reveal skeletal muscle proteome dynamics.

Shankaran M, King CL, Angel TE, Holmes WE, Li KW, Colangelo M, Price JC, Turner SM, Bell C, Hamilton KL, Miller BF, Hellerstein MK.

J Clin Invest. 2016 Jan;126(1):288-302. doi: 10.1172/JCI79639. Epub 2015 Dec 14.

14.

Type 1 diabetes immunotherapy using polyclonal regulatory T cells.

Bluestone JA, Buckner JH, Fitch M, Gitelman SE, Gupta S, Hellerstein MK, Herold KC, Lares A, Lee MR, Li K, Liu W, Long SA, Masiello LM, Nguyen V, Putnam AL, Rieck M, Sayre PH, Tang Q.

Sci Transl Med. 2015 Nov 25;7(315):315ra189. doi: 10.1126/scitranslmed.aad4134.

15.

Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice.

Thompson AC, Bruss MD, Price JC, Khambatta CF, Holmes WE, Colangelo M, Dalidd M, Roberts LS, Astle CM, Harrison DE, Hellerstein MK.

Aging Cell. 2016 Feb;15(1):118-27. doi: 10.1111/acel.12414. Epub 2015 Nov 6.

16.

Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease.

Ladell K, Hazenberg MD, Fitch M, Emson C, McEvoy-Hein Asgarian BK, Mold JE, Miller C, Busch R, Price DA, Hellerstein MK, McCune JM.

J Immunol. 2015 Nov 1;195(9):4096-105. doi: 10.4049/jimmunol.1500799. Epub 2015 Sep 28.

17.

Dynamic Proteomics: In Vivo Proteome-Wide Measurement of Protein Kinetics Using Metabolic Labeling.

Holmes WE, Angel TE, Li KW, Hellerstein MK.

Methods Enzymol. 2015;561:219-76. doi: 10.1016/bs.mie.2015.05.018. Epub 2015 Jul 17. Review.

PMID:
26358907
18.

Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice.

Johnson ML, Lalia AZ, Dasari S, Pallauf M, Fitch M, Hellerstein MK, Lanza IR.

Aging Cell. 2015 Oct;14(5):734-43. doi: 10.1111/acel.12352. Epub 2015 May 25.

19.

Turnover rates of hepatic collagen and circulating collagen-associated proteins in humans with chronic liver disease.

Decaris ML, Emson CL, Li K, Gatmaitan M, Luo F, Cattin J, Nakamura C, Holmes WE, Angel TE, Peters MG, Turner SM, Hellerstein MK.

PLoS One. 2015 Apr 24;10(4):e0123311. doi: 10.1371/journal.pone.0123311. eCollection 2015.

20.

Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib.

Charles-Schoeman C, Fleischmann R, Davignon J, Schwartz H, Turner SM, Beysen C, Milad M, Hellerstein MK, Luo Z, Kaplan IV, Riese R, Zuckerman A, McInnes IB.

Arthritis Rheumatol. 2015 Mar;67(3):616-25. doi: 10.1002/art.38974.

21.

In vivo 2H2O administration reveals impaired triglyceride storage in adipose tissue of insulin-resistant humans.

Allister CA, Liu LF, Lamendola CA, Craig CM, Cushman SW, Hellerstein MK, McLaughlin TL.

J Lipid Res. 2015 Feb;56(2):435-9. doi: 10.1194/jlr.M052860. Epub 2014 Nov 23.

22.

Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice.

Thompson AC, Bruss MD, Nag N, Kharitonenkov A, Adams AC, Hellerstein MK.

PLoS One. 2014 Nov 4;9(11):e111418. doi: 10.1371/journal.pone.0111418. eCollection 2014.

23.

Kinetics of precursor labeling in stable isotope labeling in cell cultures (SILAC) experiments.

Zhang T, Price JC, Nouri-Nigjeh E, Li J, Hellerstein MK, Qu J, Ghaemmaghami S.

Anal Chem. 2014 Nov 18;86(22):11334-41. doi: 10.1021/ac503067a. Epub 2014 Oct 29.

PMID:
25301408
24.

You are what you eat: fatty acid profiles as a method to track the habitat movement of an insect.

Bayes SK, Hellerstein MK, Fitch M, Mills NJ, Welter SC.

Oecologia. 2014 Aug;175(4):1073-80. doi: 10.1007/s00442-014-2976-9. Epub 2014 Jun 1.

PMID:
24880704
25.

Total body skeletal muscle mass: estimation by creatine (methyl-d3) dilution in humans.

Clark RV, Walker AC, O'Connor-Semmes RL, Leonard MS, Miller RR, Stimpson SA, Turner SM, Ravussin E, Cefalu WT, Hellerstein MK, Evans WJ.

J Appl Physiol (1985). 2014 Jun 15;116(12):1605-13. doi: 10.1152/japplphysiol.00045.2014. Epub 2014 Apr 24.

26.

Proteomic analysis of altered extracellular matrix turnover in bleomycin-induced pulmonary fibrosis.

Decaris ML, Gatmaitan M, FlorCruz S, Luo F, Li K, Holmes WE, Hellerstein MK, Turner SM, Emson CL.

Mol Cell Proteomics. 2014 Jul;13(7):1741-52. doi: 10.1074/mcp.M113.037267. Epub 2014 Apr 16.

27.

Greater muscle protein synthesis and mitochondrial biogenesis in males compared with females during sprint interval training.

Scalzo RL, Peltonen GL, Binns SE, Shankaran M, Giordano GR, Hartley DA, Klochak AL, Lonac MC, Paris HL, Szallar SE, Wood LM, Peelor FF 3rd, Holmes WE, Hellerstein MK, Bell C, Hamilton KL, Miller BF.

FASEB J. 2014 Jun;28(6):2705-14. doi: 10.1096/fj.13-246595. Epub 2014 Mar 5.

PMID:
24599968
28.

Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease.

Veerapathran A, Pidala J, Beato F, Betts B, Kim J, Turner JG, Hellerstein MK, Yu XZ, Janssen W, Anasetti C.

Blood. 2013 Sep 26;122(13):2251-61. doi: 10.1182/blood-2013-03-492397. Epub 2013 Aug 1.

29.

Longitudinal changes in total body creatine pool size and skeletal muscle mass using the D3-creatine dilution method.

Stimpson SA, Leonard MS, Clifton LG, Poole JC, Turner SM, Shearer TW, Remlinger KS, Clark RV, Hellerstein MK, Evans WJ.

J Cachexia Sarcopenia Muscle. 2013 Jun 25. [Epub ahead of print]

30.

A pilot study demonstrating a non-invasive method for the measurement of protein turnover in skin disorders: application to psoriasis.

Emson CL, Fitzmaurice S, Lindwall G, Li KW, Hellerstein MK, Maibach HI, Liao W, Turner SM.

Clin Transl Med. 2013 Jun 17;2:12. doi: 10.1186/2001-1326-2-12. eCollection 2013.

31.

In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1.

Holleboom AG, Jakulj L, Franssen R, Decaris J, Vergeer M, Koetsveld J, Luchoomun J, Glass A, Hellerstein MK, Kastelein JJ, Hovingh GK, Kuivenhoven JA, Groen AK, Turner SM, Stroes ES.

J Lipid Res. 2013 Jul;54(7):1964-71. doi: 10.1194/jlr.P028449. Epub 2013 May 6.

32.

Evaluation of in vivo T cell kinetics: use of heavy isotope labelling in type 1 diabetes.

Bollyky JB, Long SA, Fitch M, Bollyky PL, Rieck M, Rogers R, Samuels PL, Sanda S, Buckner JH, Hellerstein MK, Greenbaum CJ.

Clin Exp Immunol. 2013 Jun;172(3):363-74. doi: 10.1111/cei.12064.

33.

Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance.

Liew CW, Boucher J, Cheong JK, Vernochet C, Koh HJ, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng YH, Hellerstein MK, Farmer SR, Goodyear L, Doria A, Blüher M, Hsu SI, Kulkarni RN.

Nat Med. 2013 Feb;19(2):217-26. doi: 10.1038/nm.3056. Epub 2013 Jan 6.

34.

Large increases in adipose triacylglycerol flux in Cushingoid CRH-Tg mice are explained by futile cycling.

Harris C, Roohk DJ, Fitch M, Boudignon BM, Halloran BP, Hellerstein MK.

Am J Physiol Endocrinol Metab. 2013 Feb 1;304(3):E282-93. doi: 10.1152/ajpendo.00154.2012. Epub 2012 Dec 4.

35.

Calorie restriction does not increase short-term or long-term protein synthesis.

Miller BF, Robinson MM, Reuland DJ, Drake JC, Peelor FF 3rd, Bruss MD, Hellerstein MK, Hamilton KL.

J Gerontol A Biol Sci Med Sci. 2013 May;68(5):530-8. doi: 10.1093/gerona/gls219. Epub 2012 Oct 26.

36.

Mitigating factors and metabolic mechanisms in fructose-induced nonalcoholic fatty liver disease: the next challenge.

Hellerstein MK.

Am J Clin Nutr. 2012 Nov;96(5):951-2. doi: 10.3945/ajcn.112.049650. Epub 2012 Oct 10. No abstract available.

PMID:
23053554
37.

The effect of long term calorie restriction on in vivo hepatic proteostatis: a novel combination of dynamic and quantitative proteomics.

Price JC, Khambatta CF, Li KW, Bruss MD, Shankaran M, Dalidd M, Floreani NA, Roberts LS, Turner SM, Holmes WE, Hellerstein MK.

Mol Cell Proteomics. 2012 Dec;11(12):1801-14. doi: 10.1074/mcp.M112.021204. Epub 2012 Sep 13.

38.

Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration.

Fanara P, Wong PY, Husted KH, Liu S, Liu VM, Kohlstaedt LA, Riiff T, Protasio JC, Boban D, Killion S, Killian M, Epling L, Sinclair E, Peterson J, Price RW, Cabin DE, Nussbaum RL, Brühmann J, Brandt R, Christine CW, Aminoff MJ, Hellerstein MK.

J Clin Invest. 2012 Sep;122(9):3159-69. doi: 10.1172/JCI64575. Epub 2012 Aug 27.

39.

Regional cell proliferation in microdissected human prostate specimens after heavy water labeling in vivo: correlation with prostate epithelial cells isolated from seminal fluid.

Hayes GM, Simko J, Holochwost D, Kuchinsky K, Busch R, Misell L, Murphy EJ, Carroll P, Chan J, Shinohara K, Hellerstein MK.

Clin Cancer Res. 2012 Jun 15;18(12):3250-60. doi: 10.1158/1078-0432.CCR-11-2988. Epub 2012 May 2.

40.

Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-D3) dilution in rats.

Stimpson SA, Turner SM, Clifton LG, Poole JC, Mohammed HA, Shearer TW, Waitt GM, Hagerty LL, Remlinger KS, Hellerstein MK, Evans WJ.

J Appl Physiol (1985). 2012 Jun;112(11):1940-8. doi: 10.1152/japplphysiol.00122.2012. Epub 2012 Mar 15.

41.

Effect of bile acid sequestrants on glucose metabolism, hepatic de novo lipogenesis, and cholesterol and bile acid kinetics in type 2 diabetes: a randomised controlled study.

Beysen C, Murphy EJ, Deines K, Chan M, Tsang E, Glass A, Turner SM, Protasio J, Riiff T, Hellerstein MK.

Diabetologia. 2012 Feb;55(2):432-42. doi: 10.1007/s00125-011-2382-3. Epub 2011 Dec 2.

PMID:
22134839
42.

In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione.

Tchoukalova YD, Fitch M, Rogers PM, Covington JD, Henagan TM, Ye J, Hellerstein MK, Ravussin E.

Diabetes. 2012 Jan;61(1):137-44. doi: 10.2337/db10-1768. Epub 2011 Nov 28.

43.

Intraclonal complexity in chronic lymphocytic leukemia: fractions enriched in recently born/divided and older/quiescent cells.

Calissano C, Damle RN, Marsilio S, Yan XJ, Yancopoulos S, Hayes G, Emson C, Murphy EJ, Hellerstein MK, Sison C, Kaufman MS, Kolitz JE, Allen SL, Rai KR, Ivanovic I, Dozmorov IM, Roa S, Scharff MD, Li W, Chiorazzi N.

Mol Med. 2011;17(11-12):1374-82. doi: 10.2119/molmed.2011.00360. Epub 2011 Sep 23.

44.

Measurement of human plasma proteome dynamics with (2)H(2)O and liquid chromatography tandem mass spectrometry.

Price JC, Holmes WE, Li KW, Floreani NA, Neese RA, Turner SM, Hellerstein MK.

Anal Biochem. 2012 Jan 1;420(1):73-83. doi: 10.1016/j.ab.2011.09.007. Epub 2011 Sep 14.

PMID:
21964502
45.

Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype.

Ahmadian M, Abbott MJ, Tang T, Hudak CS, Kim Y, Bruss M, Hellerstein MK, Lee HY, Samuel VT, Shulman GI, Wang Y, Duncan RE, Kang C, Sul HS.

Cell Metab. 2011 Jun 8;13(6):739-48. doi: 10.1016/j.cmet.2011.05.002.

46.

Deuterium and neutrophil kinetics.

Li KW, Turner SM, Emson CL, Hellerstein MK, Dale DC.

Blood. 2011 Jun 2;117(22):6052-3; author reply 6053-4. doi: 10.1182/blood-2010-12-322271. No abstract available.

47.

Long-term synthesis rates of skeletal muscle DNA and protein are higher during aerobic training in older humans than in sedentary young subjects but are not altered by protein supplementation.

Robinson MM, Turner SM, Hellerstein MK, Hamilton KL, Miller BF.

FASEB J. 2011 Sep;25(9):3240-9. doi: 10.1096/fj.11-186437. Epub 2011 May 25.

48.

The effects of physiological adaptations to calorie restriction on global cell proliferation rates.

Bruss MD, Thompson AC, Aggarwal I, Khambatta CF, Hellerstein MK.

Am J Physiol Endocrinol Metab. 2011 Apr;300(4):E735-45. doi: 10.1152/ajpendo.00661.2010. Epub 2011 Feb 1.

49.

A dual sugar challenge test for lipogenic sensitivity to dietary fructose.

Hudgins LC, Parker TS, Levine DM, Hellerstein MK.

J Clin Endocrinol Metab. 2011 Mar;96(3):861-8. doi: 10.1210/jc.2010-2007. Epub 2011 Jan 20.

50.

Nutritional recommendations for the management of sarcopenia.

Morley JE, Argiles JM, Evans WJ, Bhasin S, Cella D, Deutz NE, Doehner W, Fearon KC, Ferrucci L, Hellerstein MK, Kalantar-Zadeh K, Lochs H, MacDonald N, Mulligan K, Muscaritoli M, Ponikowski P, Posthauer ME, Rossi Fanelli F, Schambelan M, Schols AM, Schuster MW, Anker SD; Society for Sarcopenia, Cachexia, and Wasting Disease.

J Am Med Dir Assoc. 2010 Jul;11(6):391-6. doi: 10.1016/j.jamda.2010.04.014. Review.

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