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Items: 28


Morphine decreases the function of primary human natural killer cells by both TLR4 and opioid receptor signaling.

Maher DP, Walia D, Heller NM.

Brain Behav Immun. 2020 Jan;83:298-302. doi: 10.1016/j.bbi.2019.10.011. Epub 2019 Oct 15.


Suppression of Human Natural Killer Cells by Different Classes of Opioids.

Maher DP, Walia D, Heller NM.

Anesth Analg. 2019 May;128(5):1013-1021. doi: 10.1213/ANE.0000000000004058.


Natural Killer T (NKT) Cells in Mice and Men.

Heller NM, Berga-Bolanos R, Naler L, Sen JM.

In: Soboloff J, Kappes DJ, editors. Signaling Mechanisms Regulating T Cell Diversity and Function. Boca Raton (FL): CRC Press/Taylor & Francis; 2018. Chapter 8.


Androgen and Androgen Receptor as Enhancers of M2 Macrophage Polarization in Allergic Lung Inflammation.

Becerra-Díaz M, Strickland AB, Keselman A, Heller NM.

J Immunol. 2018 Nov 15;201(10):2923-2933. doi: 10.4049/jimmunol.1800352. Epub 2018 Oct 10.


IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View.

Keegan AD, Zamorano J, Keselman A, Heller NM.

Front Immunol. 2018 May 15;9:1037. doi: 10.3389/fimmu.2018.01037. eCollection 2018. Review.


Female Sex and Gender in Lung/Sleep Health and Disease. Increased Understanding of Basic Biological, Pathophysiological, and Behavioral Mechanisms Leading to Better Health for Female Patients with Lung Disease.

Han MK, Arteaga-Solis E, Blenis J, Bourjeily G, Clegg DJ, DeMeo D, Duffy J, Gaston B, Heller NM, Hemnes A, Henske EP, Jain R, Lahm T, Lancaster LH, Lee J, Legato MJ, McKee S, Mehra R, Morris A, Prakash YS, Stampfli MR, Gopal-Srivastava R, Laposky AD, Punturieri A, Reineck L, Tigno X, Clayton J.

Am J Respir Crit Care Med. 2018 Oct 1;198(7):850-858. doi: 10.1164/rccm.201801-0168WS. Review.


Estrogen Signaling Contributes to Sex Differences in Macrophage Polarization during Asthma.

Keselman A, Fang X, White PB, Heller NM.

J Immunol. 2017 Sep 1;199(5):1573-1583. doi: 10.4049/jimmunol.1601975. Epub 2017 Jul 31.


New perspectives on the regulation of type II inflammation in asthma.

Becerra-Díaz M, Wills-Karp M, Heller NM.

F1000Res. 2017 Jun 28;6:1014. doi: 10.12688/f1000research.11198.1. eCollection 2017. Review.


Alternative activation-skewed microglia/macrophages promote hematoma resolution in experimental intracerebral hemorrhage.

Chang CF, Wan J, Li Q, Renfroe SC, Heller NM, Wang J.

Neurobiol Dis. 2017 Jul;103:54-69. doi: 10.1016/j.nbd.2017.03.016. Epub 2017 Mar 30.


Enhanced resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming.

D'Alessio FR, Craig JM, Singer BD, Files DC, Mock JR, Garibaldi BT, Fallica J, Tripathi A, Mandke P, Gans JH, Limjunyawong N, Sidhaye VK, Heller NM, Mitzner W, King LS, Aggarwal NR.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 15;310(8):L733-46. doi: 10.1152/ajplung.00419.2015. Epub 2016 Feb 19.


Hypoxia-Inducible Factor 1α Is a Critical Downstream Mediator for Hypoxia-Induced Mitogenic Factor (FIZZ1/RELMα)-Induced Pulmonary Hypertension.

Johns RA, Takimoto E, Meuchel LW, Elsaigh E, Zhang A, Heller NM, Semenza GL, Yamaji-Kegan K.

Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):134-44. doi: 10.1161/ATVBAHA.115.306710. Epub 2015 Nov 19.


Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins.

McCormick SM, Heller NM.

Front Immunol. 2015 Oct 27;6:549. doi: 10.3389/fimmu.2015.00549. eCollection 2015. Review.


β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation.

Berga-Bolaños R, Sharma A, Steinke FC, Pyaram K, Kim YH, Sultana DA, Fang JX, Chang CH, Xue HH, Heller NM, Sen JM.

BMC Immunol. 2015 Oct 19;16:62. doi: 10.1186/s12865-015-0121-0.


Commentary: IL-4 and IL-13 receptors and signaling.

McCormick SM, Heller NM.

Cytokine. 2015 Sep;75(1):38-50. doi: 10.1016/j.cyto.2015.05.023. Epub 2015 Jul 14.


Regulation of inflammation by interleukin-4: a review of "alternatives".

Luzina IG, Keegan AD, Heller NM, Rook GA, Shea-Donohue T, Atamas SP.

J Leukoc Biol. 2012 Oct;92(4):753-64. doi: 10.1189/jlb.0412214. Epub 2012 Jul 10. Review.


IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro.

Heller NM, Gwinn WM, Donnelly RP, Constant SL, Keegan AD.

PLoS One. 2012;7(6):e39673. doi: 10.1371/journal.pone.0039673. Epub 2012 Jun 28.


An atopy-associated polymorphism in the ectodomain of the IL-4R(alpha) chain (V50) regulates the persistence of STAT6 phosphorylation.

Ford AQ, Heller NM, Stephenson L, Boothby MR, Keegan AD.

J Immunol. 2009 Aug 1;183(3):1607-16. doi: 10.4049/jimmunol.0803266. Epub 2009 Jul 10.


Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages.

Heller NM, Qi X, Junttila IS, Shirey KA, Vogel SN, Paul WE, Keegan AD.

Sci Signal. 2008 Dec 23;1(51):ra17. doi: 10.1126/scisignal.1164795.


Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.

LaPorte SL, Juo ZS, Vaclavikova J, Colf LA, Qi X, Heller NM, Keegan AD, Garcia KC.

Cell. 2008 Jan 25;132(2):259-72. doi: 10.1016/j.cell.2007.12.030.


The role of post-transcriptional regulation in chemokine gene expression in inflammation and allergy.

Fan J, Heller NM, Gorospe M, Atasoy U, Stellato C.

Eur Respir J. 2005 Nov;26(5):933-47. Review.


Assessment of signal transducer and activator of transcription 6 as a target of glucocorticoid action in human airway epithelial cells.

Heller NM, Matsukura S, Georas SN, Boothby MR, Stellato C, Schleimer RP.

Clin Exp Allergy. 2004 Nov;34(11):1690-700.


Interferon-gamma inhibits STAT6 signal transduction and gene expression in human airway epithelial cells.

Heller NM, Matsukura S, Georas SN, Boothby MR, Rothman PB, Stellato C, Schleimer RP.

Am J Respir Cell Mol Biol. 2004 Nov;31(5):573-82. Epub 2004 Aug 5.


Variation in dinucleotide (GT) repeat sequence in the first exon of the STAT6 gene is associated with atopic asthma and differentially regulates the promoter activity in vitro.

Gao PS, Heller NM, Walker W, Chen CH, Moller M, Plunkett B, Roberts MH, Schleimer RP, Hopkin JM, Huang SK.

J Med Genet. 2004 Jul;41(7):535-9. No abstract available.


Expression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cells.

Kurosawa S, Myers AC, Chen L, Wang S, Ni J, Plitt JR, Heller NM, Bochner BS, Schleimer RP.

Am J Respir Cell Mol Biol. 2003 May;28(5):563-73.


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