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Items: 1 to 50 of 63

1.

The value of manure - Manure as co-product in life cycle assessment.

Leip A, Ledgard S, Uwizeye A, Palhares JCP, Aller MF, Amon B, Binder M, Cordovil CMDS, De Camillis C, Dong H, Fusi A, Helin J, Hörtenhuber S, Hristov AN, Koelsch R, Liu C, Masso C, Nkongolo NV, Patra AK, Redding MR, Rufino MC, Sakrabani R, Thoma G, Vertès F, Wang Y.

J Environ Manage. 2019 Jul 1;241:293-304. doi: 10.1016/j.jenvman.2019.03.059. Epub 2019 Apr 19.

2.

Hydrophilic Auristatin Glycoside Payload Enables Improved Antibody-Drug Conjugate Efficacy and Biocompatibility.

Satomaa T, Pynnönen H, Vilkman A, Kotiranta T, Pitkänen V, Heiskanen A, Herpers B, Price LS, Helin J, Saarinen J.

Antibodies (Basel). 2018 Mar 22;7(2). pii: E15. doi: 10.3390/antib7020015.

3.

Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody-Drug Conjugation Chemistry.

Ekholm FS, Pynnönen H, Vilkman A, Pitkänen V, Helin J, Saarinen J, Satomaa T.

ChemMedChem. 2016 Nov 21;11(22):2501-2505. doi: 10.1002/cmdc.201600372. Epub 2016 Oct 27.

PMID:
27786414
4.

Synthesis of the copper chelator TGTA and evaluation of its ability to protect biomolecules from copper induced degradation during copper catalyzed azide-alkyne bioconjugation reactions.

Ekholm FS, Pynnönen H, Vilkman A, Koponen J, Helin J, Satomaa T.

Org Biomol Chem. 2016 Jan 21;14(3):849-52. doi: 10.1039/c5ob02133b. Epub 2015 Dec 8.

PMID:
26647226
5.

Effect of catchment land use and soil type on the concentration, quality, and bacterial degradation of riverine dissolved organic matter.

Autio I, Soinne H, Helin J, Asmala E, Hoikkala L.

Ambio. 2016 Apr;45(3):331-49. doi: 10.1007/s13280-015-0724-y. Epub 2015 Nov 23.

6.

Model for quantifying the synergies between farmland biodiversity conservation and water protection at catchment scale.

Helin J, Hyytiäinen K, Korpela EL, Kuussaari M.

J Environ Manage. 2013 Dec 15;131:307-17. doi: 10.1016/j.jenvman.2013.09.029. Epub 2013 Nov 5.

PMID:
24201218
7.

Diversity in prokaryotic glycosylation: an archaeal-derived N-linked glycan contains legionaminic acid.

Kandiba L, Aitio O, Helin J, Guan Z, Permi P, Bamford DH, Eichler J, Roine E.

Mol Microbiol. 2012 May;84(3):578-93. doi: 10.1111/j.1365-2958.2012.08045.x. Epub 2012 Apr 11.

8.

The N-glycome of human embryonic stem cells.

Satomaa T, Heiskanen A, Mikkola M, Olsson C, Blomqvist M, Tiittanen M, Jaatinen T, Aitio O, Olonen A, Helin J, Hiltunen J, Natunen J, Tuuri T, Otonkoski T, Saarinen J, Laine J.

BMC Cell Biol. 2009 Jun 2;10:42. doi: 10.1186/1471-2121-10-42.

9.

Glycoforms of human endothelial CD34 that bind L-selectin carry sulfated sialyl Lewis x capped O- and N-glycans.

Hernandez Mir G, Helin J, Skarp KP, Cummings RD, Mäkitie A, Renkonen R, Leppänen A.

Blood. 2009 Jul 16;114(3):733-41. doi: 10.1182/blood-2009-03-210237. Epub 2009 Apr 9.

10.

Helicobacter pylori binding to new glycans based on N-acetyllactosamine.

Miller-Podraza H, Weikkolainen K, Larsson T, Linde P, Helin J, Natunen J, Karlsson KA.

Glycobiology. 2009 Apr;19(4):399-407. doi: 10.1093/glycob/cwn150. Epub 2008 Dec 23.

PMID:
19106234
11.

Mass spectrometric detection of tyrosine sulfation in human pancreatic trypsinogens, but not in tumor-associated trypsinogen.

Itkonen O, Helin J, Saarinen J, Kalkkinen N, Ivanov KI, Stenman UH, Valmu L.

FEBS J. 2008 Jan;275(2):289-301. Epub 2007 Dec 10.

12.

Conjugation of oligosaccharides by reductive amination to amine modified chondroitin oligomer and gamma-cyclodextrin.

Weikkolainen K, Aitio O, Blomqvist M, Natunen J, Helin J.

Glycoconj J. 2007 Apr;24(2-3):157-65. Epub 2007 Feb 1.

PMID:
17268859
13.

Cysteine cathepsins are central contributors of invasion by cultured adenosylmethionine decarboxylase-transformed rodent fibroblasts.

Ravanko K, Järvinen K, Helin J, Kalkkinen N, Hölttä E.

Cancer Res. 2004 Dec 15;64(24):8831-8.

14.

Purification and cDNA cloning of UDP-GlcNAc:GlcNAcbeta1-3Galbeta1-4Glc(NAc)-R [GlcNAc to Gal]beta1,6N-acetylglucosaminyltransferase from rat small intestine: a major carrier of dIGnT activity in rat small intestine.

Korekane H, Taguchi T, Sakamoto Y, Honke K, Dohmae N, Salminen H, Toivonen S, Helin J, Takio K, Renkonen O, Taniguchi N.

Glycobiology. 2003 May;13(5):387-400. Epub 2003 Jan 22.

PMID:
12626393
15.

NisB is required for the dehydration and NisC for the lanthionine formation in the post-translational modification of nisin.

Koponen O, Tolonen M, Qiao M, Wahlström G, Helin J, Saris PEJ.

Microbiology. 2002 Nov;148(Pt 11):3561-3568. doi: 10.1099/00221287-148-11-3561.

PMID:
12427947
16.

Enhanced activation of bound plasminogen on Staphylococcus aureus by staphylokinase.

Mölkänen T, Tyynelä J, Helin J, Kalkkinen N, Kuusela P.

FEBS Lett. 2002 Apr 24;517(1-3):72-8.

17.

Purification and characterization of novel kininogens from spotted wolffish and Atlantic cod.

Ylönen A, Helin J, Bøgwald J, Jaakola A, Rinne A, Kalkkinen N.

Eur J Biochem. 2002 Jun;269(11):2639-46.

18.

The major conformational IgE-binding epitopes of hevein (Hev b6.02) are identified by a novel chimera-based allergen epitope mapping strategy.

Karisola P, Alenius H, Mikkola J, Kalkkinen N, Helin J, Pentikäinen OT, Repo S, Reunala T, Turjanmaa K, Johnson MS, Palosuo T, Kulomaa MS.

J Biol Chem. 2002 Jun 21;277(25):22656-61. Epub 2002 Mar 21.

19.

O-glycans on human high endothelial CD34 putatively participating in L-selectin recognition.

Satomaa T, Renkonen O, Helin J, Kirveskari J, Mäkitie A, Renkonen R.

Blood. 2002 Apr 1;99(7):2609-11.

PMID:
11895802
20.
21.

Identification of four novel potato (Solanum tuberosum) allergens belonging to the family of soybean trypsin inhibitors.

Seppälä U, Majamaa H, Turjanmaa K, Helin J, Reunala T, Kalkkinen N, Palosuo T.

Allergy. 2001 Jul;56(7):619-26.

PMID:
11421919
22.

Human alpha3-fucosyltransferases convert chitin oligosaccharides to products containing a GlcNAcbeta1-4(Fucalpha1-3)GlcNAcbeta1-4R determinant at the nonreducing terminus.

Natunen J, Aitio O, Helin J, Maaheimo H, Niemelä R, Heikkinen S, Renkonen O.

Glycobiology. 2001 Mar;11(3):209-16.

PMID:
11320059
23.

Prohevein-like defense protein of tobacco is a cross-reactive allergen for latex-allergic patients.

Hänninen AR, Kalkkinen N, Mikkola JH, Helin J, Turjanmaa K, Reunala T, Palosuo T.

J Allergy Clin Immunol. 2000 Oct;106(4):778-9. No abstract available.

PMID:
11031351
24.

Functional expression of Escherichia coli enzymes synthesizing GDP-L-fucose from inherent GDP-D-mannose in Saccharomyces cerevisiae.

Mattila P, Räbinä J, Hortling S, Helin J, Renkonen R.

Glycobiology. 2000 Oct;10(10):1041-7.

PMID:
11030750
25.

Binding of glycosulfopeptides to P-selectin requires stereospecific contributions of individual tyrosine sulfate and sugar residues.

Leppänen A, White SP, Helin J, McEver RP, Cummings RD.

J Biol Chem. 2000 Dec 15;275(50):39569-78.

26.

Identification of foetal brain proteins by two-dimensional gel electrophoresis and mass spectrometry comparison of samples from individuals with or without chromosome 21 trisomy.

Oppermann M, Cols N, Nyman T, Helin J, Saarinen J, Byman I, Toran N, Alaiya AA, Bergman T, Kalkkinen N, Gonzàlez-Duarte R, Jörnvall H.

Eur J Biochem. 2000 Aug;267(15):4713-9.

27.

Toxic lactonic lipopeptide from food poisoning isolates of Bacillus licheniformis.

Mikkola R, Kolari M, Andersson MA, Helin J, Salkinoja-Salonen MS.

Eur J Biochem. 2000 Jul;267(13):4068-74. Erratum in: Eur J Biochem 2000 Sep;267(17):5655.

28.

A novel glycosulfopeptide binds to P-selectin and inhibits leukocyte adhesion to P-selectin.

Leppänen A, Mehta P, Ouyang YB, Ju T, Helin J, Moore KL, van Die I, Canfield WM, McEver RP, Cummings RD.

J Biol Chem. 1999 Aug 27;274(35):24838-48.

29.
31.

Plasmin desensitization of the PAR1 thrombin receptor: kinetics, sites of truncation, and implications for thrombolytic therapy.

Kuliopulos A, Covic L, Seeley SK, Sheridan PJ, Helin J, Costello CE.

Biochemistry. 1999 Apr 6;38(14):4572-85.

PMID:
10194379
32.
33.

N-glycan structures of matrix metalloproteinase-1 derived from human fibroblasts and from HT-1080 fibrosarcoma cells.

Saarinen J, Welgus HG, Flizar CA, Kalkkinen N, Helin J.

Eur J Biochem. 1999 Feb;259(3):829-40.

34.
36.
37.

The mitochondrial toxin produced by Streptomyces griseus strains isolated from an indoor environment is valinomycin.

Andersson MA, Mikkola R, Kroppenstedt RM, Rainey FA, Peltola J, Helin J, Sivonen K, Salkinoja-Salonen MS.

Appl Environ Microbiol. 1998 Dec;64(12):4767-73.

40.

Enzymatic synthesis of site-specifically (alpha 1-3)-fucosylated polylactosamines containing either a sialyl Lewis (x), a VIM-2, or a sialylated and internally difucosylated sequence.

Räbinä J, Natunen J, Niemelä R, Salminen H, Ilves K, Aitio O, Maaheimo H, Helin J, Renkonen O.

Carbohydr Res. 1997 Dec;305(3-4):491-9.

PMID:
9648266
41.

A novel sensitive bioassay for detection of Bacillus cereus emetic toxin and related depsipeptide ionophores.

Andersson MA, Mikkola R, Helin J, Andersson MC, Salkinoja-Salonen M.

Appl Environ Microbiol. 1998 Apr;64(4):1338-43.

42.
43.

Improved enzymatic synthesis of a highly potent oligosaccharide antagonist of L-selectin.

Salminen H, Ahokas K, Niemelä R, Penttilä L, Maaheimo H, Helin J, Costello CE, Renkonen O.

FEBS Lett. 1997 Dec 15;419(2-3):220-6.

44.

The beta 1,6-GlcNAc transferase activity present in hog gastric mucosal microsomes catalyses site-specific branch formation on a long polylactosamine backbone.

Helin J, Penttilä L, Leppänen A, Maaheimo H, Lauri S, Costello CE, Renkonen O.

FEBS Lett. 1997 Aug 4;412(3):637-42.

45.
46.

In vitro biosynthesis of a decasaccharide prototype of multiply branched polylactosaminoglycan backbones.

Leppanen A, Salminen H, Zhu Y, Maaheimo H, Helin J, Costello CE, Renkonen O.

Biochemistry. 1997 Jun 10;36(23):7026-36.

PMID:
9188700
47.

Synthesis of a new nanomolar saccharide inhibitor of lymphocyte adhesion: different polylactosamine backbones present multiple sialyl Lewis x determinants to L-selectin in high-affinity mode.

Renkonen O, Toppila S, Penttilä L, Salminen H, Helin J, Maaheimo H, Costello CE, Turunen JP, Renkonen R.

Glycobiology. 1997 Jun;7(4):453-61.

PMID:
9184825
48.
49.

Analysis of the peptidoglycan structure of Bacillus subtilis endospores.

Popham DL, Helin J, Costello CE, Setlow P.

J Bacteriol. 1996 Nov;178(22):6451-8.

50.

Enzyme-assisted synthesis of a bivalent high-affinity dodecasaccharide inhibitor of mouse gamete adhesion. The length of the chains carrying distal alpha 1,3-bonded galactose residues is critical.

Niemelä R, Penttilä L, Seppo A, Helin J, Leppänen A, Räbinä J, Uusitalo L, Maaheimo H, Taskinen J, Costello CE, et al.

FEBS Lett. 1995 Jun 19;367(1):67-72.

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