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Hippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline.

Végh MJ, Rausell A, Loos M, Heldring CM, Jurkowski W, van Nierop P, Paliukhovich I, Li KW, del Sol A, Smit AB, Spijker S, van Kesteren RE.

Mol Cell Proteomics. 2014 Nov;13(11):2975-85. doi: 10.1074/mcp.M113.032086. Epub 2014 Jul 20.


Reducing hippocampal extracellular matrix reverses early memory deficits in a mouse model of Alzheimer's disease.

Végh MJ, Heldring CM, Kamphuis W, Hijazi S, Timmerman AJ, Li KW, van Nierop P, Mansvelder HD, Hol EM, Smit AB, van Kesteren RE.

Acta Neuropathol Commun. 2014 Jun 29;2:76. doi: 10.1186/s40478-014-0076-z.

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