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Items: 1 to 50 of 110

1.

Hibernating astronauts-science or fiction?

Choukèr A, Bereiter-Hahn J, Singer D, Heldmaier G.

Pflugers Arch. 2019 Jun;471(6):819-828. doi: 10.1007/s00424-018-2244-7. Epub 2018 Dec 19. Review.

2.

Seasonal Control of Mammalian Energy Balance: Recent Advances in the Understanding of Daily Torpor and Hibernation.

Jastroch M, Giroud S, Barrett P, Geiser F, Heldmaier G, Herwig A.

J Neuroendocrinol. 2016 Nov;28(11). doi: 10.1111/jne.12437. Review.

PMID:
27755687
3.

Torpor at high ambient temperature in a neotropical didelphid, the grey short-tailed opossum (Monodelphis domestica).

Busse S, Lutter D, Heldmaier G, Jastroch M, Meyer CW.

Naturwissenschaften. 2014 Nov;101(11):1003-6. doi: 10.1007/s00114-014-1226-7. Epub 2014 Aug 21.

PMID:
25142634
4.

Brown adipose tissue dynamics in wild-type and UCP1-knockout mice: in vivo insights with magnetic resonance.

Grimpo K, Völker MN, Heppe EN, Braun S, Heverhagen JT, Heldmaier G.

J Lipid Res. 2014 Mar;55(3):398-409. doi: 10.1194/jlr.M042895. Epub 2013 Dec 16.

5.

Metabolic depression during warm torpor in the Golden spiny mouse (Acomys russatus) does not affect mitochondrial respiration and hydrogen peroxide release.

Grimpo K, Kutschke M, Kastl A, Meyer CW, Heldmaier G, Exner C, Jastroch M.

Comp Biochem Physiol A Mol Integr Physiol. 2014 Jan;167:7-14. doi: 10.1016/j.cbpa.2013.09.002. Epub 2013 Sep 8.

PMID:
24021912
6.

Brown fat in a protoendothermic mammal fuels eutherian evolution.

Oelkrug R, Goetze N, Exner C, Lee Y, Ganjam GK, Kutschke M, Müller S, Stöhr S, Tschöp MH, Crichton PG, Heldmaier G, Jastroch M, Meyer CW.

Nat Commun. 2013;4:2140. doi: 10.1038/ncomms3140.

7.

Depression of mitochondrial respiration during daily torpor of the Djungarian hamster, Phodopus sungorus, is specific for liver and correlates with body temperature.

Kutschke M, Grimpo K, Kastl A, Schneider S, Heldmaier G, Exner C, Jastroch M.

Comp Biochem Physiol A Mol Integr Physiol. 2013 Apr;164(4):584-9. doi: 10.1016/j.cbpa.2013.01.008. Epub 2013 Feb 1.

PMID:
23376108
8.

That's hot: golden spiny mice display torpor even at high ambient temperatures.

Grimpo K, Legler K, Heldmaier G, Exner C.

J Comp Physiol B. 2013 May;183(4):567-81. doi: 10.1007/s00360-012-0721-4. Epub 2012 Dec 2.

PMID:
23212435
9.

Photoperiod-dependent regulation of carboxypeptidase E affects the selective processing of neuropeptides in the seasonal Siberian hamster (Phodopus sungorus).

Helwig M, Herwig A, Heldmaier G, Barrett P, Mercer JG, Klingenspor M.

J Neuroendocrinol. 2013 Feb;25(2):190-7. doi: 10.1111/j.1365-2826.2012.02384.x.

PMID:
22967033
10.

The dietary flavonoids naringenin and quercetin acutely impair glucose metabolism in rodents possibly via inhibition of hypothalamic insulin signalling.

Koch CE, Ganjam GK, Steger J, Legler K, Stöhr S, Schumacher D, Hoggard N, Heldmaier G, Tups A.

Br J Nutr. 2013 Mar 28;109(6):1040-51. doi: 10.1017/S0007114512003005. Epub 2012 Aug 1.

PMID:
22850125
11.

Seasonal changes in thermogenesis of a free-ranging afrotherian small mammal, the Western rock elephant shrew (Elephantulus rupestris).

Oelkrug R, Meyer CW, Heldmaier G, Mzilikazi N.

J Comp Physiol B. 2012 Jul;182(5):715-27. doi: 10.1007/s00360-012-0647-x. Epub 2012 Feb 16.

PMID:
22349624
12.

Phylogenetic differences of mammalian basal metabolic rate are not explained by mitochondrial basal proton leak.

Polymeropoulos ET, Heldmaier G, Frappell PB, McAllan BM, Withers KW, Klingenspor M, White CR, Jastroch M.

Proc Biol Sci. 2012 Jan 7;279(1726):185-93. doi: 10.1098/rspb.2011.0881. Epub 2011 Jun 1.

13.

Induction of torpor: mimicking natural metabolic suppression for biomedical applications.

Bouma HR, Verhaag EM, Otis JP, Heldmaier G, Swoap SJ, Strijkstra AM, Henning RH, Carey HV.

J Cell Physiol. 2012 Apr;227(4):1285-90. doi: 10.1002/jcp.22850. Review.

PMID:
21618525
14.

Physiology. Life on low flame in hibernation.

Heldmaier G.

Science. 2011 Feb 18;331(6019):866-7. doi: 10.1126/science.1203192. No abstract available. Erratum in: Science. 2011 Apr 1;332(6025):36.

PMID:
21330523
15.

Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice.

Meyer CW, Willershäuser M, Jastroch M, Rourke BC, Fromme T, Oelkrug R, Heldmaier G, Klingenspor M.

Am J Physiol Regul Integr Comp Physiol. 2010 Nov;299(5):R1396-406. doi: 10.1152/ajpregu.00021.2009. Epub 2010 Sep 8.

16.

Torpor patterns, arousal rates, and temporal organization of torpor entry in wildtype and UCP1-ablated mice.

Oelkrug R, Heldmaier G, Meyer CW.

J Comp Physiol B. 2011 Jan;181(1):137-45. doi: 10.1007/s00360-010-0503-9. Epub 2010 Aug 1.

PMID:
20680295
17.

Seasonal changes of myostatin expression and its relation to body Mass acclimation in the Djungarian hamster, Phodopus sungorus.

Braulke LJ, Heldmaier G, Berriel Diaz M, Rozman J, Exner C.

J Exp Zool A Ecol Genet Physiol. 2010 Nov 1;313(9):548-56. doi: 10.1002/jez.626.

PMID:
20623496
18.

Uncoupling protein 1 decreases superoxide production in brown adipose tissue mitochondria.

Oelkrug R, Kutschke M, Meyer CW, Heldmaier G, Jastroch M.

J Biol Chem. 2010 Jul 16;285(29):21961-8. doi: 10.1074/jbc.M110.122861. Epub 2010 May 13.

19.

CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance.

Quarta C, Bellocchio L, Mancini G, Mazza R, Cervino C, Braulke LJ, Fekete C, Latorre R, Nanni C, Bucci M, Clemens LE, Heldmaier G, Watanabe M, Leste-Lassere T, Maitre M, Tedesco L, Fanelli F, Reuss S, Klaus S, Srivastava RK, Monory K, Valerio A, Grandis A, De Giorgio R, Pasquali R, Nisoli E, Cota D, Lutz B, Marsicano G, Pagotto U.

Cell Metab. 2010 Apr 7;11(4):273-85. doi: 10.1016/j.cmet.2010.02.015.

20.

Transabdominal ultrasonography as a monitoring tool for pregnancy in Alpine marmots (Marmota marmota).

Knauf S, Exner C, Hospes R, Heldmaier G, Wehrend A.

J Zoo Wildl Med. 2009 Dec;40(4):796-8.

PMID:
20063829
21.

Behavioural mechanisms affecting energy regulation in mice prone or resistant to diet- induced obesity.

Hesse D, Dunn M, Heldmaier G, Klingenspor M, Rozman J.

Physiol Behav. 2010 Mar 3;99(3):370-80. doi: 10.1016/j.physbeh.2009.12.001. Epub 2009 Dec 16.

PMID:
20018202
22.

UCP1 ectopically expressed in murine muscle displays native function and mitigates mitochondrial superoxide production.

Keipert S, Klaus S, Heldmaier G, Jastroch M.

Biochim Biophys Acta. 2010 Feb;1797(2):324-30. doi: 10.1016/j.bbabio.2009.11.008. Epub 2009 Dec 1.

23.

Torpor and ultradian rhythms require an intact signalling of the sympathetic nervous system.

Braulke LJ, Heldmaier G.

Cryobiology. 2010 Apr;60(2):198-203. doi: 10.1016/j.cryobiol.2009.11.001. Epub 2009 Nov 12.

PMID:
19913528
24.

Keep cool: memory is retained during hibernation in Alpine marmots.

Clemens LE, Heldmaier G, Exner C.

Physiol Behav. 2009 Aug 4;98(1-2):78-84. doi: 10.1016/j.physbeh.2009.04.013. Epub 2009 Apr 23.

PMID:
19393672
25.

High energy digestion efficiency and altered lipid metabolism contribute to obesity in BFMI mice.

Meyer CW, Wagener A, Rink N, Hantschel C, Heldmaier G, Klingenspor M, Brockmann GA.

Obesity (Silver Spring). 2009 Nov;17(11):1988-93. doi: 10.1038/oby.2009.124. Epub 2009 Apr 23.

26.

Photoperiodic regulation of satiety mediating neuropeptides in the brainstem of the seasonal Siberian hamster (Phodopus sungorus).

Helwig M, Archer ZA, Heldmaier G, Tups A, Mercer JG, Klingenspor M.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2009 Jul;195(7):631-42. doi: 10.1007/s00359-009-0438-3. Epub 2009 Apr 5.

PMID:
19347341
27.

Systemic first-line phenotyping.

Gailus-Durner V, Fuchs H, Adler T, Aguilar Pimentel A, Becker L, Bolle I, Calzada-Wack J, Dalke C, Ehrhardt N, Ferwagner B, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Mörth C, Mossbrugger I, Naton B, Prehn C, Puk O, Rathkolb B, Rozman J, Schrewe A, Thiele F, Adamski J, Aigner B, Behrendt H, Busch DH, Favor J, Graw J, Heldmaier G, Ivandic B, Katus H, Klingenspor M, Klopstock T, Kremmer E, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf E, Wurst W, de Angelis MH.

Methods Mol Biol. 2009;530:463-509. doi: 10.1007/978-1-59745-471-1_25.

PMID:
19266331
28.

The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models.

Fuchs H, Gailus-Durner V, Adler T, Pimentel JA, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Dalke C, Ehrhardt N, Fasnacht N, Ferwagner B, Frischmann U, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Maier H, Mossbrugger I, Mörth C, Naton B, Nöth U, Pasche B, Prehn C, Przemeck G, Puk O, Racz I, Rathkolb B, Rozman J, Schäble K, Schreiner R, Schrewe A, Sina C, Steinkamp R, Thiele F, Willershäuser M, Zeh R, Adamski J, Busch DH, Beckers J, Behrendt H, Daniel H, Esposito I, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Klingenspor M, Klopstock T, Lengeling A, Mempel M, Müller W, Neschen S, Ollert M, Quintanilla-Martinez L, Rosenstiel P, Schmidt J, Schreiber S, Schughart K, Schulz H, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M.

Curr Pharm Biotechnol. 2009 Feb;10(2):236-43.

PMID:
19199957
29.

Energetics of tropical hibernation.

Dausmann KH, Glos J, Heldmaier G.

J Comp Physiol B. 2009 Apr;179(3):345-57. doi: 10.1007/s00360-008-0318-0. Epub 2008 Dec 2.

PMID:
19048262
30.

On the use of the time axis for ecological separation: diel rhythms as an evolutionary constraint.

Kronfeld-Schor N, Dayan T, Elvert R, Haim A, Zisapel N, Heldmaier G.

Am Nat. 2001 Oct;158(4):451-7. doi: 10.1086/321991. No abstract available.

PMID:
18707339
31.

Brown adipose tissue specific lack of uncoupling protein 3 is associated with impaired cold tolerance and reduced transcript levels of metabolic genes.

Nau K, Fromme T, Meyer CW, von Praun C, Heldmaier G, Klingenspor M.

J Comp Physiol B. 2008 Mar;178(3):269-77. Epub 2007 Nov 7.

PMID:
17987299
32.

Marsupial uncoupling protein 1 sheds light on the evolution of mammalian nonshivering thermogenesis.

Jastroch M, Withers KW, Taudien S, Frappell PB, Helwig M, Fromme T, Hirschberg V, Heldmaier G, McAllan BM, Firth BT, Burmester T, Platzer M, Klingenspor M.

Physiol Genomics. 2008 Jan 17;32(2):161-9. Epub 2007 Oct 30.

PMID:
17971503
33.

3-Iodothyronamine: a novel hormone controlling the balance between glucose and lipid utilisation.

Braulke LJ, Klingenspor M, DeBarber A, Tobias SC, Grandy DK, Scanlan TS, Heldmaier G.

J Comp Physiol B. 2008 Feb;178(2):167-77. Epub 2007 Oct 3.

PMID:
17912534
34.

Power matters in closing the phenotyping gap.

Meyer CW, Elvert R, Scherag A, Ehrhardt N, Gailus-Durner V, Fuchs H, Schäfer H, Hrabé de Angelis M, Heldmaier G, Klingenspor M.

Naturwissenschaften. 2007 May;94(5):401-6. Epub 2007 Jan 10.

PMID:
17216184
35.

Telemetric monitoring of tracheal pressure after tracheal occlusion for treatment of severe congenital diaphragmatic hernia.

Hellmeyer L, Exner C, Folz B, Hiller M, Sierra F, Lukasewitz P, Steinfeld T, Werner JA, Heldmaier G, Schmidt S.

Arch Gynecol Obstet. 2007 Apr;275(4):245-8. Epub 2006 Sep 20.

PMID:
17021771
36.

Expanding the body mass range: associations between BMR and tissue morphology in wild type and mutant dwarf mice (David mice).

Meyer CW, Neubronner J, Rozman J, Stumm G, Osanger A, Stoeger C, Augustin M, Grosse J, Klingenspor M, Heldmaier G.

J Comp Physiol B. 2007 Feb;177(2):183-92. Epub 2006 Sep 29.

PMID:
17009045
37.

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.

Haemmerle G, Lass A, Zimmermann R, Gorkiewicz G, Meyer C, Rozman J, Heldmaier G, Maier R, Theussl C, Eder S, Kratky D, Wagner EF, Klingenspor M, Hoefler G, Zechner R.

Science. 2006 May 5;312(5774):734-7.

38.

Evidence for Nr4a1 as a cold-induced effector of brown fat thermogenesis.

Kanzleiter T, Schneider T, Walter I, Bolze F, Eickhorst C, Heldmaier G, Klaus S, Klingenspor M.

Physiol Genomics. 2005 Dec 14;24(1):37-44. Epub 2005 Oct 11.

PMID:
16219868
39.

Introducing the German Mouse Clinic: open access platform for standardized phenotyping.

Gailus-Durner V, Fuchs H, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Elvert R, Ehrhardt N, Dalke C, Franz TJ, Grundner-Culemann E, Hammelbacher S, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kalaydjiev SV, Klempt M, Kling E, Kunder S, Lengger C, Lisse T, Mijalski T, Naton B, Pedersen V, Prehn C, Przemeck G, Racz I, Reinhard C, Reitmeir P, Schneider I, Schrewe A, Steinkamp R, Zybill C, Adamski J, Beckers J, Behrendt H, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Kirchhof P, Klingenspor M, Klopstock T, Lengeling A, Müller W, Ohl F, Ollert M, Quintanilla-Martinez L, Schmidt J, Schulz H, Wolf E, Wurst W, Zimmer A, Busch DH, de Angelis MH.

Nat Methods. 2005 Jun;2(6):403-4. No abstract available.

PMID:
15908916
40.
41.

Adaptive mechanisms during food restriction in Acomys russatus: the use of torpor for desert survival.

Ehrhardt N, Heldmaier G, Exner C.

J Comp Physiol B. 2005 Apr;175(3):193-200. Epub 2005 Mar 2.

PMID:
15742195
42.

Hibernation in the tropics: lessons from a primate.

Dausmann KH, Glos J, Ganzhorn JU, Heldmaier G.

J Comp Physiol B. 2005 Apr;175(3):147-55. Epub 2005 Jan 29.

PMID:
15682314
43.

Gene or size: metabolic rate and body temperature in obese growth hormone-deficient dwarf mice.

Meyer CW, Klingenspor M, Rozman J, Heldmaier G.

Obes Res. 2004 Sep;12(9):1509-18.

44.

Natural hypometabolism during hibernation and daily torpor in mammals.

Heldmaier G, Ortmann S, Elvert R.

Respir Physiol Neurobiol. 2004 Aug 12;141(3):317-29. Review.

PMID:
15288602
45.

Depression of transcription and translation during daily torpor in the Djungarian hamster (Phodopus sungorus).

Berriel Diaz M, Lange M, Heldmaier G, Klingenspor M.

J Comp Physiol B. 2004 Aug;174(6):495-502. Epub 2004 Jun 30.

PMID:
15232707
46.

Physiology: hibernation in a tropical primate.

Dausmann KH, Glos J, Ganzhorn JU, Heldmaier G.

Nature. 2004 Jun 24;429(6994):825-6.

PMID:
15215852
47.

Absence of UCP3 in brown adipose tissue does not impair nonshivering thermogenesis.

Liebig M, von Praun C, Heldmaier G, Klingenspor M.

Physiol Biochem Zool. 2004 Jan-Feb;77(1):116-26.

PMID:
15057722
48.

Hormonal and behavioural changes during the mating season and pregnancy in Alpine marmots (Marmota marmota).

Exner C, Wehrend A, Hospes R, Einspanier A, Hoffmann B, Heldmaier G.

Reproduction. 2003 Dec;126(6):775-82.

PMID:
14748696
49.

A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity.

Meyer CW, Korthaus D, Jagla W, Cornali E, Grosse J, Fuchs H, Klingenspor M, Roemheld S, Tschöp M, Heldmaier G, De Angelis MH, Nehls M.

Endocrinology. 2004 May;145(5):2531-41. Epub 2004 Jan 15.

PMID:
14726450
50.

Energetic constraints on sexual activity in the male edible dormouse (Glis glis).

Fietz J, Schlund W, Dausmann KH, Regelmann M, Heldmaier G.

Oecologia. 2004 Jan;138(2):202-9. Epub 2003 Nov 8.

PMID:
14608499

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