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Items: 1 to 50 of 60

1.

Inhibition of integrin αVβ6 changes fibril thickness of stromal collagen in experimental carcinomas.

Olof Olsson P, Gustafsson R, Salnikov AV, Göthe M, Zeller KS, Friman T, Baldetorp B, Koopman LA, Weinreb PH, Violette SM, Kalamajski S, Heldin NE, Rubin K.

Cell Commun Signal. 2018 Jul 2;16(1):36. doi: 10.1186/s12964-018-0249-7.

2.

Increased fibrosis and interstitial fluid pressure in two different types of syngeneic murine carcinoma grown in integrin β3-subunit deficient mice.

Friman T, Gustafsson R, Stuhr LB, Chidiac J, Heldin NE, Reed RK, Oldberg A, Rubin K.

PLoS One. 2012;7(3):e34082. doi: 10.1371/journal.pone.0034082. Epub 2012 Mar 30.

3.

Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.

Zhao M, Sano D, Pickering CR, Jasser SA, Henderson YC, Clayman GL, Sturgis EM, Ow TJ, Lotan R, Carey TE, Sacks PG, Grandis JR, Sidransky D, Heldin NE, Myers JN.

Clin Cancer Res. 2011 Dec 1;17(23):7248-64. doi: 10.1158/1078-0432.CCR-11-0690. Epub 2011 Aug 25.

4.

Nuclear cysteine cathepsin variants in thyroid carcinoma cells.

Tedelind S, Poliakova K, Valeta A, Hunegnaw R, Yemanaberhan EL, Heldin NE, Kurebayashi J, Weber E, Kopitar-Jerala N, Turk B, Bogyo M, Brix K.

Biol Chem. 2010 Aug;391(8):923-35. doi: 10.1515/BC.2010.109.

5.

Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors.

Wensman H, Heldin NE, Pejler G, Hellmén E.

PLoS One. 2009 Sep 22;4(9):e7133. doi: 10.1371/journal.pone.0007133.

6.

Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas.

Wensman H, Göransson H, Leuchowius KJ, Strömberg S, Pontén F, Isaksson A, Rutteman GR, Heldin NE, Pejler G, Hellmén E.

Breast Cancer Res Treat. 2009 Nov;118(2):333-43. doi: 10.1007/s10549-008-0243-7. Epub 2008 Dec 2.

PMID:
19048371
7.

Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma.

Oldberg A, Kalamajski S, Salnikov AV, Stuhr L, Mörgelin M, Reed RK, Heldin NE, Rubin K.

Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):13966-71. Epub 2007 Aug 22.

8.

Molecular cytogenetic profiles of novel and established human anaplastic thyroid carcinoma models.

Lee JJ, Foukakis T, Hashemi J, Grimelius L, Heldin NE, Wallin G, Rudduck C, Lui WO, Höög A, Larsson C.

Thyroid. 2007 Apr;17(4):289-301.

PMID:
17465858
9.

Immuno-PET of undifferentiated thyroid carcinoma with radioiodine-labelled antibody cMAb U36: application to antibody tumour uptake studies.

Fortin MA, Salnikov AV, Nestor M, Heldin NE, Rubin K, Lundqvist H.

Eur J Nucl Med Mol Imaging. 2007 Sep;34(9):1376-87. Epub 2007 Feb 3.

PMID:
17277931
10.

Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma.

Salnikov AV, Heldin NE, Stuhr LB, Wiig H, Gerber H, Reed RK, Rubin K.

Int J Cancer. 2006 Dec 15;119(12):2795-802.

11.

2-methoxyestradiol induces apoptosis in cultured human anaplastic thyroid carcinoma cells.

Roswall P, Bu S, Rubin K, Landström M, Heldin NE.

Thyroid. 2006 Feb;16(2):143-50.

PMID:
16676399
12.

Differential effects of TGF-beta1 on telomerase activity in thyroid carcinoma cell lines.

Lindkvist A, Franzén A, Ren ZP, Heldin NE, Paulsson-Karlsson Y.

Biochem Biophys Res Commun. 2005 Dec 23;338(3):1625-33. Epub 2005 Nov 2.

PMID:
16288728
13.

Planning for intracavitary anti-EGFR radionuclide therapy of gliomas. Literature review and data on EGFR expression.

Carlsson J, Ren ZP, Wester K, Sundberg AL, Heldin NE, Hesselager G, Persson M, Gedda L, Tolmachev V, Lundqvist H, Blomquist E, Nistér M.

J Neurooncol. 2006 Mar;77(1):33-45. Review.

PMID:
16200342
14.

Induction of apoptosis or necrosis in human endometrial carcinoma cells by 2-methoxyestradiol.

Li L, Heldin NE, Grawé J, Ulmsten U, Fu X.

Anticancer Res. 2004 Nov-Dec;24(6):3983-90.

15.
16.

Hyaluronan content in experimental carcinoma is not correlated to interstitial fluid pressure.

Jacobson A, Salnikov A, Lammerts E, Roswall P, Sundberg C, Heldin P, Rubin K, Heldin NE.

Biochem Biophys Res Commun. 2003 Jun 13;305(4):1017-23.

PMID:
12767932
17.
18.
19.

Interference with TGF-beta1 and -beta3 in tumor stroma lowers tumor interstitial fluid pressure independently of growth in experimental carcinoma.

Lammerts E, Roswall P, Sundberg C, Gotwals PJ, Koteliansky VE, Reed RK, Heldin NE, Rubin K.

Int J Cancer. 2002 Dec 10;102(5):453-62.

20.

Mechanisms for 2-methoxyestradiol-induced apoptosis of prostate cancer cells.

Bu S, Blaukat A, Fu X, Heldin NE, Landström M.

FEBS Lett. 2002 Nov 6;531(2):141-51.

22.

Collagen type I expression in experimental anaplastic thyroid carcinoma: regulation and relevance for tumorigenicity.

Dahlman T, Lammerts E, Bergström D, Franzén A, Westermark K, Heldin NE, Rubin K.

Int J Cancer. 2002 Mar 10;98(2):186-92.

23.

BMP-7-induced cell cycle arrest of anaplastic thyroid carcinoma cells via p21(CIP1) and p27(KIP1).

Franzén A, Heldin NE.

Biochem Biophys Res Commun. 2001 Jul 20;285(3):773-81.

PMID:
11453659
24.
25.

Epidermal growth factor receptor signaling activates met in human anaplastic thyroid carcinoma cells.

Bergström JD, Westermark B, Heldin NE.

Exp Cell Res. 2000 Aug 25;259(1):293-9.

PMID:
10942601
26.

Fibrosis in undifferentiated (anaplastic) thyroid carcinomas: evidence for a dual action of tumour cells in collagen type I synthesis.

Dahlman T, Lammerts E, Wik M, Bergström D, Grimelius L, Westermark K, Rubin K, Heldin NE.

J Pathol. 2000 Aug;191(4):376-86.

PMID:
10918212
27.

Smad7 mediates apoptosis induced by transforming growth factor beta in prostatic carcinoma cells.

Landström M, Heldin NE, Bu S, Hermansson A, Itoh S, ten Dijke P, Heldin CH.

Curr Biol. 2000 May 4;10(9):535-8.

28.
29.
30.

Lack of responsiveness to TGF-beta1 in a thyroid carcinoma cell line with functional type I and type II TGF-beta receptors and Smad proteins, suggests a novel mechanism for TGF-beta insensitivity in carcinoma cells.

Heldin NE, Bergström D, Hermansson A, Bergenstråhle A, Nakao A, Westermark B, ten Dijke P.

Mol Cell Endocrinol. 1999 Jul 20;153(1-2):79-90.

PMID:
10459856
31.

Non-autocrine, constitutive activation of Met in human anaplastic thyroid carcinoma cells in culture.

Bergström JD, Hermansson A, Diaz de Ståhl T, Heldin NE.

Br J Cancer. 1999 May;80(5-6):650-6.

32.

Analysis of mutations in exon 1 of the human thyrotropin receptor gene: high frequency of the D36H and P52T polymorphic variants.

Simanainen J, Kinch A, Westermark K, Winsa B, Bengtsson M, Schuppert F, Westermark B, Heldin NE.

Thyroid. 1999 Jan;9(1):7-11.

PMID:
10037069
33.
34.

Transforming growth factor beta1 induces nuclear export of inhibitory Smad7.

Itóh S, Landström M, Hermansson A, Itoh F, Heldin CH, Heldin NE, ten Dijke P.

J Biol Chem. 1998 Oct 30;273(44):29195-201.

35.

Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members.

Afrakhte M, Morén A, Jossan S, Itoh S, Sampath K, Westermark B, Heldin CH, Heldin NE, ten Dijke P.

Biochem Biophys Res Commun. 1998 Aug 19;249(2):505-11.

PMID:
9712726
36.

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling.

Nakao A, Afrakhte M, Morén A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P.

Nature. 1997 Oct 9;389(6651):631-5.

PMID:
9335507
37.

CD97: a dedifferentiation marker in human thyroid carcinomas.

Aust G, Eichler W, Laue S, Lehmann I, Heldin NE, Lotz O, Scherbaum WA, Dralle H, Hoang-Vu C.

Cancer Res. 1997 May 1;57(9):1798-806.

38.

Decreased growth rate and tumour formation of human anaplastic thyroid carcinoma cells transfected with a human thyrotropin receptor cDNA in NMRI nude mice treated with propylthiouracil.

Gustavsson B, Hermansson A, Andersson AC, Grimelius L, Bergh J, Westermark B, Heldin NE.

Mol Cell Endocrinol. 1996 Aug 9;121(2):143-51.

PMID:
8892315
39.

Expression of tumour necrosis factor-alpha (TNF-alpha) mRNA and protein in pathological thyroid tissue and carcinoma cell lines.

Aust G, Heuer M, Laue S, Lehmann I, Hofmann A, Heldin NE, Scherbaum WA.

Clin Exp Immunol. 1996 Jul;105(1):148-154.

40.

EGF-receptors in human normal and pathological thyroid tissue.

Westermark K, Lundqvist M, Wallin G, Dahlman T, Hacker GW, Heldin NE, Grimelius L.

Histopathology. 1996 Mar;28(3):221-7.

PMID:
8729040
41.

Functional analysis of a variant of the thyrotropin receptor gene in a family with Graves' disease.

Gustavsson B, Eklöf C, Westermark K, Westermark B, Heldin NE.

Mol Cell Endocrinol. 1995 Jun;111(2):167-73.

PMID:
7556878
42.

A study on the oncogenes gli, fos, jun and met in human uterine leiomyomas.

Havel G, Heldin N, Wedell B, Johansson R, Mark J.

Int J Oncol. 1994 Nov;5(5):1093-7.

PMID:
21559685
43.

Thyrotropin receptor and leukocyte adhesion molecules in autoimmune thyroid disease: a study of their gene expression by northern blot analysis and in situ hybridization.

Schuppert F, Reiser M, Heldin NE, Ede S, Scheumann GF, Dralle H, von zur Mühlen A.

Eur J Endocrinol. 1994 Nov;131(5):480-8.

PMID:
7524954
44.
45.
46.
47.

Expression levels of the thyrotropin receptor gene in autoimmune thyroid disease: coregulation with parameters of thyroid function and inverse relation to major histocompatibility complex classes I and II.

Schuppert F, Reiser M, Scheumann GF, Heldin NE, Pring-Akerblom P, Ede S, Haverkamp G, Dralle H, Von zur Mühlen A.

J Clin Endocrinol Metab. 1993 May;76(5):1349-56.

PMID:
8496329
48.

A somatic point mutation in a putative ligand binding domain of the TSH receptor in a patient with autoimmune hyperthyroidism.

Heldin NE, Gustavsson B, Westermark K, Westermark B.

J Clin Endocrinol Metab. 1991 Dec;73(6):1374-6.

PMID:
1955520
49.

The molecular biology of the human anaplastic thyroid carcinoma cell.

Heldin NE, Westermark B.

Thyroidology. 1991 Dec;3(3):127-31.

PMID:
1726928
50.

Coexpression of functionally active receptors for thyrotropin and platelet-derived growth factor in human thyroid carcinoma cells.

Heldin NE, Cvejić D, Smeds S, Westermark B.

Endocrinology. 1991 Oct;129(4):2187-93.

PMID:
1655394

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