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Items: 1 to 50 of 95

1.

UVC-Emitting LuPO4:Pr3+ Nanoparticles Decrease Radiation Resistance of Hypoxic Cancer Cells.

Müller M, Espinoza S, Jüstel T, Held KD, Anderson RR, Purschke M.

Radiat Res. 2019 Nov 18. doi: 10.1667/RR15491.1. [Epub ahead of print]

PMID:
31738663
2.

X-irradiation of developing hippocampal neurons causes changes in neuron population phenotypes, dendritic morphology and synaptic protein expression in surviving neurons at maturity.

Puspitasari A, Yamazaki H, Kawamura H, Nakano T, Takahashi A, Shirao T, Held KD.

Neurosci Res. 2019 Nov 8. pii: S0168-0102(19)30320-7. doi: 10.1016/j.neures.2019.11.002. [Epub ahead of print]

3.

p53 deficiency augments nucleolar instability after ionizing irradiation.

Kakoti S, Yamauchi M, Gu W, Kato R, Yasuhara T, Hagiwara Y, Laskar S, Oike T, Sato H, Held KD, Nakano T, Shibata A.

Oncol Rep. 2019 Dec;42(6):2293-2302. doi: 10.3892/or.2019.7341. Epub 2019 Sep 27.

4.

Radiation epidemiology and health effects following low-level radiation exposure.

Boice JD, Held KD, Shore RE.

J Radiol Prot. 2019 Jul 4;39(4):S14-S27. doi: 10.1088/1361-6498/ab2f3d. [Epub ahead of print]

PMID:
31272090
5.

Base excision repair regulates PD-L1 expression in cancer cells.

Permata TBM, Hagiwara Y, Sato H, Yasuhara T, Oike T, Gondhowiardjo S, Held KD, Nakano T, Shibata A.

Oncogene. 2019 Jun;38(23):4452-4466. doi: 10.1038/s41388-019-0733-6. Epub 2019 Feb 12.

PMID:
30755733
6.

Report of the AAPM TG-256 on the relative biological effectiveness of proton beams in radiation therapy.

Paganetti H, Blakely E, Carabe-Fernandez A, Carlson DJ, Das IJ, Dong L, Grosshans D, Held KD, Mohan R, Moiseenko V, Niemierko A, Stewart RD, Willers H.

Med Phys. 2019 Mar;46(3):e53-e78. doi: 10.1002/mp.13390. Epub 2019 Feb 14.

PMID:
30661238
7.

Photoinactivation of Neisseria gonorrhoeae: A Paradigm-Changing Approach for Combating Antibiotic-Resistant Gonococcal Infection.

Wang Y, Ferrer-Espada R, Baglo Y, Goh XS, Held KD, Grad YH, Gu Y, Gelfand JA, Dai T.

J Infect Dis. 2019 Jul 31;220(5):873-881. doi: 10.1093/infdis/jiz018.

PMID:
30629196
8.

TOPAS-nBio: An Extension to the TOPAS Simulation Toolkit for Cellular and Sub-cellular Radiobiology.

Schuemann J, McNamara AL, Ramos-Méndez J, Perl J, Held KD, Paganetti H, Incerti S, Faddegon B.

Radiat Res. 2019 Feb;191(2):125-138. doi: 10.1667/RR15226.1. Epub 2019 Jan 4.

9.

Increased Chromosome Aberrations in Cells Exposed Simultaneously to Simulated Microgravity and Radiation.

Hada M, Ikeda H, Rhone JR, Beitman AJ, Plante I, Souda H, Yoshida Y, Held KD, Fujiwara K, Saganti PB, Takahashi A.

Int J Mol Sci. 2018 Dec 22;20(1). pii: E43. doi: 10.3390/ijms20010043.

10.

UV scintillating particles as radiosensitizer enhance cell killing after X-ray excitation.

Müller M, Wang Y, Squillante MR, Held KD, Anderson RR, Purschke M.

Radiother Oncol. 2018 Dec;129(3):589-594. doi: 10.1016/j.radonc.2018.06.016. Epub 2018 Jun 29.

11.

Clustered DNA double-strand break formation and the repair pathway following heavy-ion irradiation.

Hagiwara Y, Oike T, Niimi A, Yamauchi M, Sato H, Limsirichaikul S, Held KD, Nakano T, Shibata A.

J Radiat Res. 2019 Jan 1;60(1):69-79. doi: 10.1093/jrr/rry096. Review.

12.

A New Standard DNA Damage (SDD) Data Format.

Schuemann J, McNamara AL, Warmenhoven JW, Henthorn NT, Kirkby KJ, Merchant MJ, Ingram S, Paganetti H, Held KD, Ramos-Mendez J, Faddegon B, Perl J, Goodhead DT, Plante I, Rabus H, Nettelbeck H, Friedland W, Kundrát P, Ottolenghi A, Baiocco G, Barbieri S, Dingfelder M, Incerti S, Villagrasa C, Bueno M, Bernal MA, Guatelli S, Sakata D, Brown JMC, Francis Z, Kyriakou I, Lampe N, Ballarini F, Carante MP, Davídková M, Štěpán V, Jia X, Cucinotta FA, Schulte R, Stewart RD, Carlson DJ, Galer S, Kuncic Z, Lacombe S, Milligan J, Cho SH, Sawakuchi G, Inaniwa T, Sato T, Li W, Solov'yov AV, Surdutovich E, Durante M, Prise KM, McMahon SJ.

Radiat Res. 2019 Jan;191(1):76-92. doi: 10.1667/RR15209.1. Epub 2018 Nov 8.

13.

Proceedings of the National Cancer Institute Workshop on Charged Particle Radiobiology.

Mohan R, Held KD, Story MD, Grosshans D, Capala J.

Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):816-831. doi: 10.1016/j.ijrobp.2017.12.260. Epub 2017 Dec 21. Review. Erratum in: Int J Radiat Oncol Biol Phys. 2018 Jul 15;101(4):1004.

PMID:
29485053
14.

3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation.

Hagiwara Y, Niimi A, Isono M, Yamauchi M, Yasuhara T, Limsirichaikul S, Oike T, Sato H, Held KD, Nakano T, Shibata A.

Oncotarget. 2017 Nov 25;8(65):109370-109381. doi: 10.18632/oncotarget.22679. eCollection 2017 Dec 12.

15.

DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells.

Sato H, Niimi A, Yasuhara T, Permata TBM, Hagiwara Y, Isono M, Nuryadi E, Sekine R, Oike T, Kakoti S, Yoshimoto Y, Held KD, Suzuki Y, Kono K, Miyagawa K, Nakano T, Shibata A.

Nat Commun. 2017 Nov 24;8(1):1751. doi: 10.1038/s41467-017-01883-9.

16.

Correction to: Held and Hamada, Summary of the Bill Morgan Memorial Symposium - part 1: biology, epidemiology and radiation protection.

Held KD, Hamada N.

Int J Radiat Biol. 2017 Oct;93(10):x. doi: 10.1080/09553002.2017.1359999. Epub 2017 Aug 2. No abstract available.

PMID:
28766988
17.

Summary of the Bill Morgan Memorial Symposium - part 1: biology, epidemiology and radiation protection.

Held KD, Hamada N.

Int J Radiat Biol. 2017 Oct;93(10):1054-1055. doi: 10.1080/09553002.2017.1344364. Epub 2017 Jul 13. No abstract available. Erratum in: Int J Radiat Biol. 2017 Oct;93(10 ):x.

PMID:
28635554
18.

Introduction to the Bill Morgan Memorial Special Issue on Biology, Epidemiology, and Implications for Radiation Protection.

Hamada N, Salomaa S, Held KD, Boice JD Jr.

Int J Radiat Biol. 2017 Oct;93(10):1003-1008. doi: 10.1080/09553002.2017.1342148. Epub 2017 Jul 20. No abstract available.

PMID:
28612672
19.

Development and performance evaluation of a three-dimensional clinostat synchronized heavy-ion irradiation system.

Ikeda H, Souda H, Puspitasari A, Held KD, Hidema J, Nikawa T, Yoshida Y, Kanai T, Takahashi A.

Life Sci Space Res (Amst). 2017 Feb;12:51-60. doi: 10.1016/j.lssr.2017.01.003. Epub 2017 Jan 23.

PMID:
28212708
20.

Use of the NASA Space Radiation Laboratory at Brookhaven National Laboratory to Conduct Charged Particle Radiobiology Studies Relevant to Ion Therapy.

Held KD, Blakely EA, Story MD, Lowenstein DI.

Radiat Res. 2016 Jun;185(6):563-7. doi: 10.1667/RR14412.1. Epub 2016 May 19.

21.

Identification of DNA double strand breaks at chromosome boundaries along the track of particle irradiation.

Niimi A, Yamauchi M, Limsirichaikul S, Sekine R, Oike T, Sato H, Suzuki K, Held KD, Nakano T, Shibata A.

Genes Chromosomes Cancer. 2016 Aug;55(8):650-60. doi: 10.1002/gcc.22367. Epub 2016 May 16.

PMID:
27113385
22.

Disruption of SLX4-MUS81 Function Increases the Relative Biological Effectiveness of Proton Radiation.

Liu Q, Underwood TS, Kung J, Wang M, Lu HM, Paganetti H, Held KD, Hong TS, Efstathiou JA, Willers H.

Int J Radiat Oncol Biol Phys. 2016 May 1;95(1):78-85. doi: 10.1016/j.ijrobp.2016.01.046. Epub 2016 Feb 1.

23.

Effects of Charged Particles on Human Tumor Cells.

Held KD, Kawamura H, Kaminuma T, Paz AE, Yoshida Y, Liu Q, Willers H, Takahashi A.

Front Oncol. 2016 Feb 12;6:23. doi: 10.3389/fonc.2016.00023. eCollection 2016. Review.

24.

NCRP Program Area Committee 1: Basic Criteria, Epidemiology, Radiobiology and Risk.

Held KD, Woloschak GE.

Health Phys. 2016 Feb;110(2):98-100. doi: 10.1097/HP.0000000000000402.

25.

Education and Training Needs in the Radiation Sciences: Problems and Potential Solutions.

Dynlacht JR, Zeman EM, Held KD, Deye J, Vikram B, Joiner MC.

Radiat Res. 2015 Nov;184(5):449-55. doi: 10.1667/RR14199.1. Epub 2015 Oct 19.

PMID:
26479274
26.

Lung cancer cell line screen links fanconi anemia/BRCA pathway defects to increased relative biological effectiveness of proton radiation.

Liu Q, Ghosh P, Magpayo N, Testa M, Tang S, Gheorghiu L, Biggs P, Paganetti H, Efstathiou JA, Lu HM, Held KD, Willers H.

Int J Radiat Oncol Biol Phys. 2015 Apr 1;91(5):1081-9. doi: 10.1016/j.ijrobp.2014.12.046.

PMID:
25832698
27.

Adapting a drug screening platform to discover associations of molecular targeted radiosensitizers with genomic biomarkers.

Liu Q, Wang M, Kern AM, Khaled S, Han J, Yeap BY, Hong TS, Settleman J, Benes CH, Held KD, Efstathiou JA, Willers H.

Mol Cancer Res. 2015 Apr;13(4):713-20. doi: 10.1158/1541-7786.MCR-14-0570. Epub 2015 Feb 9.

28.

Vascular endothelial growth factor-C enhances radiosensitivity of lymphatic endothelial cells.

Kesler CT, Kuo AH, Wong HK, Masuck DJ, Shah JL, Kozak KR, Held KD, Padera TP.

Angiogenesis. 2014 Apr;17(2):419-27. doi: 10.1007/s10456-013-9400-7. Epub 2013 Nov 8.

29.

Immunologically augmented cancer treatment using modern radiotherapy.

Durante M, Reppingen N, Held KD.

Trends Mol Med. 2013 Sep;19(9):565-82. doi: 10.1016/j.molmed.2013.05.007. Epub 2013 Jul 4. Review.

PMID:
23831337
30.

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

Liu Q, Xu C, Kirubakaran S, Zhang X, Hur W, Liu Y, Kwiatkowski NP, Wang J, Westover KD, Gao P, Ercan D, Niepel M, Thoreen CC, Kang SA, Patricelli MP, Wang Y, Tupper T, Altabef A, Kawamura H, Held KD, Chou DM, Elledge SJ, Janne PA, Wong KK, Sabatini DM, Gray NS.

Cancer Res. 2013 Apr 15;73(8):2574-86. doi: 10.1158/0008-5472.CAN-12-1702. Epub 2013 Feb 22.

31.

Summary: achievements, critical issues, and thoughts on the future.

Held KD.

Health Phys. 2012 Nov;103(5):681-4. doi: 10.1097/HP.0b013e318264b2f5.

32.

Relative biological effectiveness (RBE) and out-of-field cell survival responses to passive scattering and pencil beam scanning proton beam deliveries.

Butterworth KT, McGarry CK, Clasie B, Carabe-Fernandez A, Schuemann J, Depauw N, Tang S, McMahon SJ, Schettino G, O'Sullivan JM, Lu HM, Kooy H, Paganetti H, Hounsell AR, Held KD, Prise KM.

Phys Med Biol. 2012 Oct 21;57(20):6671-80. doi: 10.1088/0031-9155/57/20/6671. Epub 2012 Oct 1.

PMID:
23022765
33.

Differential bystander signaling between radioresistant chondrosarcoma cells and fibroblasts after x-ray, proton, iron ion and carbon ion exposures.

Wakatsuki M, Magpayo N, Kawamura H, Held KD.

Int J Radiat Oncol Biol Phys. 2012 Sep 1;84(1):e103-8. doi: 10.1016/j.ijrobp.2012.02.052. Epub 2012 Apr 24.

PMID:
22537542
34.

Effects of very low fluences of high-energy protons or iron ions on irradiated and bystander cells.

Yang H, Magpayo N, Rusek A, Chiang IH, Sivertz M, Held KD.

Radiat Res. 2011 Dec;176(6):695-705. Epub 2011 Oct 12.

PMID:
21988573
35.

Targeted and non-targeted effects from combinations of low doses of energetic protons and iron ions in human fibroblasts.

Yang H, Magpayo N, Held KD.

Int J Radiat Biol. 2011 Mar;87(3):311-9. doi: 10.3109/09553002.2010.537431. Epub 2010 Dec 15.

PMID:
21158498
36.

Phototoxicity of Hoechst 33342 in time-lapse fluorescence microscopy.

Purschke M, Rubio N, Held KD, Redmond RW.

Photochem Photobiol Sci. 2010 Dec;9(12):1634-9. doi: 10.1039/c0pp00234h. Epub 2010 Oct 8.

PMID:
20931137
37.

American Society for Radiation Oncology (ASTRO) survey of radiation biology educators in U.S. and Canadian radiation oncology residency programs.

Rosenstein BS, Held KD, Rockwell S, Williams JP, Zeman EM.

Int J Radiat Oncol Biol Phys. 2009 Nov 1;75(3):896-905. doi: 10.1016/j.ijrobp.2009.05.009. Epub 2009 Sep 3.

38.

Ionizing radiation-induced bystander mutagenesis and adaptation: quantitative and temporal aspects.

Zhang Y, Zhou J, Baldwin J, Held KD, Prise KM, Redmond RW, Liber HL.

Mutat Res. 2009 Dec 1;671(1-2):20-5. doi: 10.1016/j.mrfmmm.2009.08.006. Epub 2009 Aug 18.

39.

Bystander effects induced by diffusing mediators after photodynamic stress.

Chakraborty A, Held KD, Prise KM, Liber HL, Redmond RW.

Radiat Res. 2009 Jul;172(1):74-81. doi: 10.1667/RR1669.1.

40.

FANCD2-deficient human fibroblasts are hypersensitive to ionising radiation at oxygen concentrations of 0% and 3% but not under normoxic conditions.

Kuhnert VM, Kachnic LA, Li L, Purschke M, Gheorghiu L, Lee R, Held KD, Willers H.

Int J Radiat Biol. 2009 Jun;85(6):523-31. doi: 10.1080/09553000902883810.

41.

Real-time imaging of novel spatial and temporal responses to photodynamic stress.

Rubio N, Rajadurai A, Held KD, Prise KM, Liber HL, Redmond RW.

Free Radic Biol Med. 2009 Aug 1;47(3):283-90. doi: 10.1016/j.freeradbiomed.2009.04.024. Epub 2009 May 3.

PMID:
19409981
42.

Effects of low fluences of radiations found in space on cellular systems.

Held KD.

Int J Radiat Biol. 2009 May;85(5):379-90. doi: 10.1080/09553000902838558. Review.

PMID:
19382021
43.

Estrogen enhanced cell-cell signalling in breast cancer cells exposed to targeted irradiation.

Shao C, Folkard M, Held KD, Prise KM.

BMC Cancer. 2008 Jun 30;8:184. doi: 10.1186/1471-2407-8-184.

44.

Biomarkers and mechanisms of FANCD2 function.

Willers H, Kachnic LA, Luo CM, Li L, Purschke M, Borgmann K, Held KD, Powell SN.

J Biomed Biotechnol. 2008;2008:821529. doi: 10.1155/2008/821529.

45.

Deficiencies of double-strand break repair factors and effects on mutagenesis in directly gamma-irradiated and medium-mediated bystander human lymphoblastoid cells.

Zhang Y, Zhou J, Held KD, Redmond RW, Prise KM, Liber HL.

Radiat Res. 2008 Feb;169(2):197-206. doi: 10.1667/RR1189.1.

PMID:
18220473
46.

Effects of heavy ions and energetic protons on normal human fibroblasts.

Yang H, Anzenberg V, Held KD.

Radiats Biol Radioecol. 2007 May-Jun;47(3):302-6.

PMID:
17867499
47.
48.

Do the dietary supplements epigallocatechin gallate or vitamin e cause a radiomodifying response on tumors in vivo? A pilot study with murine breast carcinoma.

Lawenda BD, Smith DE, Xu L, Niemierko A, Silverstein JR, Boucher Y, Kashiwagi S, Held KD, Jain RK, Loeffler JS, Eisenberg DM, Blumberg JB.

J Soc Integr Oncol. 2007 Winter;5(1):11-7.

PMID:
17309809
49.

Introduction to clinical radiation biology.

Willers H, Held KD.

Hematol Oncol Clin North Am. 2006 Feb;20(1):1-24. Review.

PMID:
16580554
50.

New insights on cell death from radiation exposure.

Prise KM, Schettino G, Folkard M, Held KD.

Lancet Oncol. 2005 Jul;6(7):520-8. Review.

PMID:
15992701

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