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Items: 1 to 50 of 87

1.

Evaluating the effects of water matrix constituents on micropollutant removal by activated carbon and β-cyclodextrin polymer adsorbents.

Ling Y, Alzate-Sánchez DM, Klemes MJ, Dichtel WR, Helbling DE.

Water Res. 2020 Apr 15;173:115551. doi: 10.1016/j.watres.2020.115551. Epub 2020 Jan 27.

PMID:
32032887
2.

The mitochondrial carrier Citrin plays a role in regulating cellular energy during carcinogenesis.

Rabinovich S, Silberman A, Adler L, Agron S, Levin-Zaidman S, Bahat A, Porat Z, Ben-Zeev E, Geva I, Itkin M, Malitsky S, Buchaklian A, Helbling D, Dimmock D, Erez A.

Oncogene. 2020 Jan;39(1):164-175. doi: 10.1038/s41388-019-0976-2. Epub 2019 Aug 28.

PMID:
31462712
3.

Fall Creek Monitoring Station: Using Environmental Covariates To Predict Micropollutant Dynamics and Peak Events in Surface Water Systems.

Carpenter CMG, Wong LYJ, Gutema DL, Helbling DE.

Environ Sci Technol. 2019 Aug 6;53(15):8599-8610. doi: 10.1021/acs.est.9b02665. Epub 2019 Jul 19.

PMID:
31280559
4.

Metastatic Mixed Adenoneuroendocrine Carcinoma of the Colon with Response to Immunotherapy with Pembrolizumab: A Case Report.

Stueger A, Winder T, Tinguely M, Petrausch U, Helbling D.

J Immunother. 2019 Sep;42(7):274-277. doi: 10.1097/CJI.0000000000000279.

PMID:
31219972
5.

Reduction of a Tetrafluoroterephthalonitrile-β-Cyclodextrin Polymer to Remove Anionic Micropollutants and Perfluorinated Alkyl Substances from Water.

Klemes MJ, Ling Y, Ching C, Wu C, Xiao L, Helbling DE, Dichtel WR.

Angew Chem Int Ed Engl. 2019 Aug 26;58(35):12049-12053. doi: 10.1002/anie.201905142. Epub 2019 Jul 24.

PMID:
31210007
6.

De novo loss-of-function KCNMA1 variants are associated with a new multiple malformation syndrome and a broad spectrum of developmental and neurological phenotypes.

Liang L, Li X, Moutton S, Schrier Vergano SA, Cogné B, Saint-Martin A, Hurst ACE, Hu Y, Bodamer O, Thevenon J, Hung CY, Isidor B, Gerard B, Rega A, Nambot S, Lehalle D, Duffourd Y, Thauvin-Robinet C, Faivre L, Bézieau S, Dure LS, Helbling DC, Bick D, Xu C, Chen Q, Mancini GMS, Vitobello A, Wang QK.

Hum Mol Genet. 2019 Sep 1;28(17):2937-2951. doi: 10.1093/hmg/ddz117.

PMID:
31152168
7.

Surface water and groundwater analysis using aryl hydrocarbon and endocrine receptor biological assays and liquid chromatography-high resolution mass spectrometry in Susquehanna County, PA.

Bamberger M, Nell M, Ahmed AH, Santoro R, Ingraffea AR, Kennedy RF, Nagel SC, Helbling DE, Oswald RE.

Environ Sci Process Impacts. 2019 Jun 19;21(6):988-998. doi: 10.1039/c9em00112c.

8.

Exploring co-occurrence patterns between organic micropollutants and bacterial community structure in a mixed-use watershed.

Gao H, LaVergne JM, Carpenter CMG, Desai R, Zhang X, Gray K, Helbling DE, Wells GF.

Environ Sci Process Impacts. 2019 May 22;21(5):867-880. doi: 10.1039/c8em00588e.

PMID:
30957808
9.

Biotransformation of antibiotics: Exploring the activity of extracellular and intracellular enzymes derived from wastewater microbial communities.

Zumstein MT, Helbling DE.

Water Res. 2019 May 15;155:115-123. doi: 10.1016/j.watres.2019.02.024. Epub 2019 Feb 25.

PMID:
30836263
10.

QSARs to predict adsorption affinity of organic micropollutants for activated carbon and β-cyclodextrin polymer adsorbents.

Ling Y, Klemes MJ, Steinschneider S, Dichtel WR, Helbling DE.

Water Res. 2019 May 1;154:217-226. doi: 10.1016/j.watres.2019.02.012. Epub 2019 Feb 16.

PMID:
30798176
11.

β-Cyclodextrin Polymers on Microcrystalline Cellulose as a Granular Media for Organic Micropollutant Removal from Water.

Alzate-Sánchez DM, Ling Y, Li C, Frank BP, Bleher R, Fairbrother DH, Helbling DE, Dichtel WR.

ACS Appl Mater Interfaces. 2019 Feb 27;11(8):8089-8096. doi: 10.1021/acsami.8b22100. Epub 2019 Feb 15.

PMID:
30715844
12.

Severe Neonatal RYR1 Myopathy With Pathological Features of Congenital Muscular Dystrophy.

Helbling DC, Mendoza D, McCarrier J, Vanden Avond MA, Harmelink MM, Barkhaus PE, Basel D, Lawlor MW.

J Neuropathol Exp Neurol. 2019 Mar 1;78(3):283-287. doi: 10.1093/jnen/nlz004.

13.

Phenolation of cyclodextrin polymers controls their lead and organic micropollutant adsorption.

Klemes MJ, Ling Y, Chiapasco M, Alsbaiee A, Helbling DE, Dichtel WR.

Chem Sci. 2018 Sep 24;9(47):8883-8889. doi: 10.1039/c8sc03267j. eCollection 2018 Dec 21.

14.

Cetuximab monotherapy and cetuximab plus capecitabine as first-line treatment in older patients with RAS- and BRAF wild-type metastatic colorectal cancer. Results of the multicenter phase II trial SAKK 41/10.

Kienle DL, Dietrich D, Ribi K, Wicki A, Quagliata L, Winterhalder RC, Koeberle D, Horber D, Bastian S, Kueng M, Saletti P, Helbling D, Baertschi D, Lugli A, Bernhard J, Andrieu C, von Moos R.

J Geriatr Oncol. 2019 Mar;10(2):304-310. doi: 10.1016/j.jgo.2018.11.011. Epub 2018 Dec 14.

PMID:
30559073
15.

Fall Creek Monitoring Station: Highly Resolved Temporal Sampling to Prioritize the Identification of Nontarget Micropollutants in a Small Stream.

Carpenter CMG, Wong LYJ, Johnson CA, Helbling DE.

Environ Sci Technol. 2019 Jan 2;53(1):77-87. doi: 10.1021/acs.est.8b05320. Epub 2018 Dec 12.

PMID:
30472836
16.

Removal of GenX and Perfluorinated Alkyl Substances from Water by Amine-Functionalized Covalent Organic Frameworks.

Ji W, Xiao L, Ling Y, Ching C, Matsumoto M, Bisbey RP, Helbling DE, Dichtel WR.

J Am Chem Soc. 2018 Oct 10;140(40):12677-12681. doi: 10.1021/jacs.8b06958. Epub 2018 Oct 2.

PMID:
30256633
17.

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.

Lee JS, Adler L, Karathia H, Carmel N, Rabinovich S, Auslander N, Keshet R, Stettner N, Silberman A, Agemy L, Helbling D, Eilam R, Sun Q, Brandis A, Malitsky S, Itkin M, Weiss H, Pinto S, Kalaora S, Levy R, Barnea E, Admon A, Dimmock D, Stern-Ginossar N, Scherz A, Nagamani SCS, Unda M, Wilson DM 3rd, Elhasid R, Carracedo A, Samuels Y, Hannenhalli S, Ruppin E, Erez A.

Cell. 2018 Sep 6;174(6):1559-1570.e22. doi: 10.1016/j.cell.2018.07.019. Epub 2018 Aug 9.

18.

Evaluating the environmental parameters that determine aerobic biodegradation half-lives of pesticides in soil with a multivariable approach.

Wang Y, Lai A, Latino D, Fenner K, Helbling DE.

Chemosphere. 2018 Oct;209:430-438. doi: 10.1016/j.chemosphere.2018.06.077. Epub 2018 Jun 14.

PMID:
29936116
19.

Sdha+/- Rats Display Minimal Muscle Pathology Without Significant Behavioral or Biochemical Abnormalities.

Siebers EM, Choi MJ, Tinklenberg JA, Beatka MJ, Ayres S, Meng H, Helbling DC, Takizawa A, Bennett B, Garces AM, Dias Duarte Machado LG, Dimmock D, Dwinell MR, Geurts AM, Lawlor MW.

J Neuropathol Exp Neurol. 2018 Aug 1;77(8):665-672. doi: 10.1093/jnen/nly042.

20.
21.

Widespread Micropollutant Monitoring in the Hudson River Estuary Reveals Spatiotemporal Micropollutant Clusters and Their Sources.

Carpenter CMG, Helbling DE.

Environ Sci Technol. 2018 Jun 5;52(11):6187-6196. doi: 10.1021/acs.est.8b00945. Epub 2018 May 16.

PMID:
29742349
22.

Tetrafluoroterephthalonitrile-crosslinked β-cyclodextrin polymers for efficient extraction and recovery of organic micropollutants from water.

Li C, Klemes MJ, Dichtel WR, Helbling DE.

J Chromatogr A. 2018 Mar 16;1541:52-56. doi: 10.1016/j.chroma.2018.02.012. Epub 2018 Feb 6.

PMID:
29433822
23.

Clinical heterogeneity of mitochondrial NAD kinase deficiency caused by a NADK2 start loss variant.

Pomerantz DJ, Ferdinandusse S, Cogan J, Cooper DN, Reimschisel T, Robertson A, Bican A, McGregor T, Gauthier J, Millington DS, Andrae JLW, Tschannen MR, Helbling DC, Demos WM, Denis S, Wanders RJA, Newman JN, Hamid R, Phillips JA 3rd; Collaborators of UDN.

Am J Med Genet A. 2018 Mar;176(3):692-698. doi: 10.1002/ajmg.a.38602. Epub 2018 Feb 1. Review.

24.

Cigarette smoking as a risk factor for the development of and mortality from hepatocellular carcinoma: An updated systematic review of 81 epidemiological studies.

Abdel-Rahman O, Helbling D, Schöb O, Eltobgy M, Mohamed H, Schmidt J, Giryes A, Mehrabi A, Iype S, John H, Tekbas A, Zidan A, Oweira H.

J Evid Based Med. 2017 Nov;10(4):245-254. doi: 10.1111/jebm.12270. Epub 2017 Sep 10. Review.

PMID:
28891275
25.

Correction to "β-Cyclodextrin Polymer Network Sequesters Perfluorooctanoic Acid at Environmentally Relevant Concentrations".

Xiao L, Ling Y, Alsbaiee A, Li C, Helbling DE, Dichtel WR.

J Am Chem Soc. 2017 Aug 2;139(30):10585. doi: 10.1021/jacs.7b06995. Epub 2017 Jul 21. No abstract available.

26.

Impact of liver transplantation on the risk of second malignant tumors among hepatocellular carcinoma patients.

Oweira H, Schmidt J, Helbling D, Petrausch U, Schöb O, Mehrabi A, Giryes A, Elhadedy H, Abdel-Rahman O.

Expert Rev Gastroenterol Hepatol. 2017 Sep;11(9):865-869. doi: 10.1080/17474124.2017.1355235. Epub 2017 Jul 18.

PMID:
28697656
27.

β-Cyclodextrin Polymer Network Sequesters Perfluorooctanoic Acid at Environmentally Relevant Concentrations.

Xiao L, Ling Y, Alsbaiee A, Li C, Helbling DE, Dichtel WR.

J Am Chem Soc. 2017 Jun 14;139(23):7689-7692. doi: 10.1021/jacs.7b02381. Epub 2017 May 30. Erratum in: J Am Chem Soc. 2017 Aug 2;139(30):10585.

28.

Benchmarking Micropollutant Removal by Activated Carbon and Porous β-Cyclodextrin Polymers under Environmentally Relevant Scenarios.

Ling Y, Klemes MJ, Xiao L, Alsbaiee A, Dichtel WR, Helbling DE.

Environ Sci Technol. 2017 Jul 5;51(13):7590-7598. doi: 10.1021/acs.est.7b00906. Epub 2017 Jun 13.

29.

Immune-related neurological toxicities among solid tumor patients treated with immune checkpoint inhibitors: a systematic review.

Eltobgy M, Oweira H, Petrausch U, Helbling D, Schmidt J, Mehrabi A, Schöb O, Giryes A, Decker M, Abdel-Rahman O.

Expert Rev Neurother. 2017 Jul;17(7):725-736. doi: 10.1080/14737175.2017.1336088. Epub 2017 May 31.

PMID:
28548892
30.

Successful Application of Whole Genome Sequencing in a Medical Genetics Clinic.

Bick D, Fraser PC, Gutzeit MF, Harris JM, Hambuch TM, Helbling DC, Jacob HJ, Kersten JN, Leuthner SR, May T, North PE, Prisco SZ, Schuler BA, Shimoyama M, Strong KA, Van Why SK, Veith R, Verbsky J, Weborg AM Jr, Wilk BM, Willoughby RE Jr, Worthey EA, Dimmock DP.

J Pediatr Genet. 2017 Jun;6(2):61-76. doi: 10.1055/s-0036-1593968. Epub 2016 Nov 28.

31.

Removal of micropollutants in biofilters: Hydrodynamic effects on biofilm assembly and functioning.

Carpenter CMG, Helbling DE.

Water Res. 2017 Sep 1;120:211-221. doi: 10.1016/j.watres.2017.04.071. Epub 2017 May 2.

PMID:
28494247
32.

Early stage hepatocellular carcinoma in the elderly: A SEER database analysis.

Oweira H, Petrausch U, Helbling D, Schmidt J, Mannhart M, Mehrabi A, Schöb O, Giryes A, Abdel-Rahman O.

J Geriatr Oncol. 2017 Jul;8(4):277-283. doi: 10.1016/j.jgo.2017.03.002. Epub 2017 Apr 4.

PMID:
28389117
33.

X-Linked Cobalamin Disorder (HCFC1) Mimicking Nonketotic Hyperglycinemia With Increased Both Cerebrospinal Fluid Glycine and Methylmalonic Acid.

Scalais E, Osterheld E, Weitzel C, De Meirleir L, Mataigne F, Martens G, Shaikh TH, Coughlin CR 2nd, Yu HC, Swanson M, Friederich MW, Scharer G, Helbling D, Wendt-Andrae J, Van Hove JLK.

Pediatr Neurol. 2017 Jun;71:65-69. doi: 10.1016/j.pediatrneurol.2016.12.003. Epub 2017 Jan 7.

PMID:
28363510
34.

Prognostic value of site-specific metastases in pancreatic adenocarcinoma: A Surveillance Epidemiology and End Results database analysis.

Oweira H, Petrausch U, Helbling D, Schmidt J, Mannhart M, Mehrabi A, Schöb O, Giryes A, Decker M, Abdel-Rahman O.

World J Gastroenterol. 2017 Mar 14;23(10):1872-1880. doi: 10.3748/wjg.v23.i10.1872.

35.

Immune-related ocular toxicities in solid tumor patients treated with immune checkpoint inhibitors: a systematic review.

Abdel-Rahman O, Oweira H, Petrausch U, Helbling D, Schmidt J, Mannhart M, Mehrabi A, Schöb O, Giryes A.

Expert Rev Anticancer Ther. 2017 Apr;17(4):387-394. doi: 10.1080/14737140.2017.1296765. Epub 2017 Feb 24. Review.

PMID:
28277102
36.

Prognostic value of site-specific extra-hepatic disease in hepatocellular carcinoma: a SEER database analysis.

Oweira H, Petrausch U, Helbling D, Schmidt J, Mehrabi A, Schöb O, Giryes A, Abdel-Rahman O.

Expert Rev Gastroenterol Hepatol. 2017 Jul;11(7):695-701. doi: 10.1080/17474124.2017.1294485. Epub 2017 Feb 23.

PMID:
28276812
37.

Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection.

Mitzelfelt KA, McDermott-Roe C, Grzybowski MN, Marquez M, Kuo CT, Riedel M, Lai S, Choi MJ, Kolander KD, Helbling D, Dimmock DP, Battle MA, Jou CJ, Tristani-Firouzi M, Verbsky JW, Benjamin IJ, Geurts AM.

Stem Cell Reports. 2017 Mar 14;8(3):491-499. doi: 10.1016/j.stemcr.2017.01.021. Epub 2017 Feb 24.

38.

Intraperitoneal chemotherapy and cytoreductive surgery for peritoneal metastases coupled with curative treatment of colorectal liver metastases: an updated systematic review.

El-Nakeep S, Rashad N, Oweira H, Schmidt J, Helbling D, Giryes A, Petrausch U, Mehrabi A, Decker M, Abdel-Rahman O.

Expert Rev Gastroenterol Hepatol. 2017 Mar;11(3):249-258. doi: 10.1080/17474124.2017.1284586. Epub 2017 Feb 7. Review.

PMID:
28099818
39.

Relative contribution of ammonia oxidizing bacteria and other members of nitrifying activated sludge communities to micropollutant biotransformation.

Men Y, Achermann S, Helbling DE, Johnson DR, Fenner K.

Water Res. 2017 Feb 1;109:217-226. doi: 10.1016/j.watres.2016.11.048. Epub 2016 Nov 22.

PMID:
27898334
40.

Treatment-related Death in Cancer Patients Treated with Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysis.

Abdel-Rahman O, Helbling D, Schmidt J, Petrausch U, Giryes A, Mehrabi A, Schöb O, Mannhart M, Oweira H.

Clin Oncol (R Coll Radiol). 2017 Apr;29(4):218-230. doi: 10.1016/j.clon.2016.11.007. Epub 2016 Nov 25. Review.

PMID:
27894673
41.

A non-target approach to identify disinfection byproducts of structurally similar sulfonamide antibiotics.

Wang M, Helbling DE.

Water Res. 2016 Oct 1;102:241-251. doi: 10.1016/j.watres.2016.06.042. Epub 2016 Jun 23.

PMID:
27348196
42.

Treatment-associated Fatigue in Cancer Patients Treated with Immune Checkpoint Inhibitors; a Systematic Review and Meta-analysis.

Abdel-Rahman O, Helbling D, Schmidt J, Petrausch U, Giryes A, Mehrabi A, Schöb O, Mannhart M, Zidan A, Oweira H.

Clin Oncol (R Coll Radiol). 2016 Oct;28(10):e127-38. doi: 10.1016/j.clon.2016.06.008. Epub 2016 Jun 20. Review.

PMID:
27339403
43.

Can meta-omics help to establish causality between contaminant biotransformations and genes or gene products?

Johnson DR, Helbling DE, Men Y, Fenner K.

Environ Sci (Camb). 2015 May 1;1(3):272-278. Epub 2015 Mar 25.

44.

Biotransformation of Two Pharmaceuticals by the Ammonia-Oxidizing Archaeon Nitrososphaera gargensis.

Men Y, Han P, Helbling DE, Jehmlich N, Herbold C, Gulde R, Onnis-Hayden A, Gu AZ, Johnson DR, Wagner M, Fenner K.

Environ Sci Technol. 2016 May 3;50(9):4682-92. doi: 10.1021/acs.est.5b06016. Epub 2016 Apr 19.

45.

Systematic Exploration of Biotransformation Reactions of Amine-Containing Micropollutants in Activated Sludge.

Gulde R, Meier U, Schymanski EL, Kohler HP, Helbling DE, Derrer S, Rentsch D, Fenner K.

Environ Sci Technol. 2016 Mar 15;50(6):2908-20. doi: 10.1021/acs.est.5b05186. Epub 2016 Feb 26.

PMID:
26864277
46.

Potentially diagnostic electron paramagnetic resonance spectra elucidate the underlying mechanism of mitochondrial dysfunction in the deoxyguanosine kinase deficient rat model of a genetic mitochondrial DNA depletion syndrome.

Bennett B, Helbling D, Meng H, Jarzembowski J, Geurts AM, Friederich MW, Van Hove JLK, Lawlor MW, Dimmock DP.

Free Radic Biol Med. 2016 Mar;92:141-151. doi: 10.1016/j.freeradbiomed.2016.01.001. Epub 2016 Jan 8.

47.

Rapid removal of organic micropollutants from water by a porous β-cyclodextrin polymer.

Alsbaiee A, Smith BJ, Xiao L, Ling Y, Helbling DE, Dichtel WR.

Nature. 2016 Jan 14;529(7585):190-4. doi: 10.1038/nature16185. Epub 2015 Dec 21.

PMID:
26689365
48.

Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.

Rabinovich S, Adler L, Yizhak K, Sarver A, Silberman A, Agron S, Stettner N, Sun Q, Brandis A, Helbling D, Korman S, Itzkovitz S, Dimmock D, Ulitsky I, Nagamani SC, Ruppin E, Erez A.

Nature. 2015 Nov 19;527(7578):379-383. doi: 10.1038/nature15529. Epub 2015 Nov 11.

49.

Necrotizing Enterocolitis Is Not Associated With Sequence Variants in Antioxidant Response Genes in Premature Infants.

Sampath V, Helbling D, Menden H, Dimmock D, Mulrooney NP, Murray JC, Dagle JM, Garland JS.

J Pediatr Gastroenterol Nutr. 2016 Mar;62(3):420-3. doi: 10.1097/MPG.0000000000000988.

50.

SIGIRR genetic variants in premature infants with necrotizing enterocolitis.

Sampath V, Menden H, Helbling D, Li K, Gastonguay A, Ramchandran R, Dimmock DP.

Pediatrics. 2015 Jun;135(6):e1530-4. doi: 10.1542/peds.2014-3386. Epub 2015 May 11.

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