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Maternal immune activation during pregnancy impacts on brain structure and function in the adult offspring.

Kreitz S, Zambon A, Ronovsky M, Budinsky L, Helbich TH, Sideromenos S, Ivan C, Konerth L, Wank I, Berger A, Pollak A, Hess A, Pollak DD.

Brain Behav Immun. 2019 Sep 14. pii: S0889-1591(19)30178-3. doi: 10.1016/j.bbi.2019.09.011. [Epub ahead of print]


Subarachnoid hemorrhage in rats - Visualizing blood distribution in vivo using gadolinium-enhanced magnetic resonance imaging: Technical note.

Simader E, Budinsky L, Helbich TH, Sherif C, Höftberger R, Kasprian G, Raunegger T, Hacker P, Ankersmit HJ, Beer L, Haider T.

J Neurosci Methods. 2019 Sep 1;325:108370. doi: 10.1016/j.jneumeth.2019.108370. Epub 2019 Jul 19.


Multiparametric 18F-FDG PET-MRI of the breast: are there differences in imaging biomarkers of contralateral healthy tissue between patients with and without breast cancer?

Leithner D, Helbich TH, Bernard-Davila B, Marino MA, Avendano D, Martinez DF, Jochelson M, Kapetas P, Baltzer PA, Haug A, Hacker M, Tanyildizi Y, Morris EA, Pinker K.

J Nucl Med. 2019 Jun 28. pii: jnumed.119.230003. doi: 10.2967/jnumed.119.230003. [Epub ahead of print]


Brain leptin reduces liver lipids by increasing hepatic triglyceride secretion and lowering lipogenesis.

Hackl MT, Fürnsinn C, Schuh CM, Krssak M, Carli F, Guerra S, Freudenthaler A, Baumgartner-Parzer S, Helbich TH, Luger A, Zeyda M, Gastaldelli A, Buettner C, Scherer T.

Nat Commun. 2019 Jun 20;10(1):2717. doi: 10.1038/s41467-019-10684-1.


A multiparametric [18F]FDG PET/MRI diagnostic model including imaging biomarkers of the tumor and contralateral healthy breast tissue aids breast cancer diagnosis.

Leithner D, Horvat JV, Bernard-Davila B, Helbich TH, Ochoa-Albiztegui RE, Martinez DF, Zhang M, Thakur SB, Wengert GJ, Staudenherz A, Jochelson MS, Morris EA, Baltzer PAT, Clauser P, Kapetas P, Pinker K.

Eur J Nucl Med Mol Imaging. 2019 Aug;46(9):1878-1888. doi: 10.1007/s00259-019-04331-6. Epub 2019 Jun 13.


Intra- and inter-observer variability in dependence of T1-time correction for common dynamic contrast enhanced MRI parameters in prostate cancer patients.

Daniel M, Polanec SH, Wengert G, Clauser P, Pinker K, Helbich TH, Georg D, Baltzer PAT.

Eur J Radiol. 2019 Jul;116:27-33. doi: 10.1016/j.ejrad.2019.04.015. Epub 2019 Apr 23.


Diffusion-Weighted MRI of Breast Cancer: Improved Lesion Visibility and Image Quality Using Synthetic b-Values.

Bickel H, Polanec SH, Wengert G, Pinker K, Bogner W, Helbich TH, Baltzer PA.

J Magn Reson Imaging. 2019 May 28. doi: 10.1002/jmri.26809. [Epub ahead of print]


CD8+ T cells induce cachexia during chronic viral infection.

Baazim H, Schweiger M, Moschinger M, Xu H, Scherer T, Popa A, Gallage S, Ali A, Khamina K, Kosack L, Vilagos B, Smyth M, Lercher A, Friske J, Merkler D, Aderem A, Helbich TH, Heikenwälder M, Lang PA, Zechner R, Bergthaler A.

Nat Immunol. 2019 Jun;20(6):701-710. doi: 10.1038/s41590-019-0397-y. Epub 2019 May 20.


Multimodal [18 F]FDG PET/CT Is a Direct Readout for Inflammatory Bone Repair: A Longitudinal Study in TNFα Transgenic Mice.

Hayer S, Zeilinger M, Weiss V, Dumanic M, Seibt M, Niederreiter B, Shvets T, Pichler F, Wadsak W, Podesser BK, Helbich TH, Hacker M, Smolen JS, Redlich K, Mitterhauser M.

J Bone Miner Res. 2019 Sep;34(9):1632-1645. doi: 10.1002/jbmr.3748. Epub 2019 Jul 30.


Automatic segmentation and classification of breast lesions through identification of informative multiparametric PET/MRI features.

Vogl WD, Pinker K, Helbich TH, Bickel H, Grabner G, Bogner W, Gruber S, Bago-Horvath Z, Dubsky P, Langs G.

Eur Radiol Exp. 2019 Apr 27;3(1):18. doi: 10.1186/s41747-019-0096-3.


[Contrast agent-free breast MRI : Advantages and potential disadvantages].

Baltzer PAT, Kapetas P, Sodano C, Dietzel M, Pinker K, Helbich TH, Clauser P.

Radiologe. 2019 Jun;59(6):510-516. doi: 10.1007/s00117-019-0524-7. Review. German.


Can we reduce the workload of mammographic screening by automatic identification of normal exams with artificial intelligence? A feasibility study.

Rodriguez-Ruiz A, Lång K, Gubern-Merida A, Teuwen J, Broeders M, Gennaro G, Clauser P, Helbich TH, Chevalier M, Mertelmeier T, Wallis MG, Andersson I, Zackrisson S, Sechopoulos I, Mann RM.

Eur Radiol. 2019 Sep;29(9):4825-4832. doi: 10.1007/s00330-019-06186-9. Epub 2019 Apr 16.


A Single-Arm, Multicenter Validation Study of Prostate Cancer Localization and Aggressiveness With a Quantitative Multiparametric Magnetic Resonance Imaging Approach.

Maas MC, Litjens GJS, Wright AJ, Attenberger UI, Haider MA, Helbich TH, Kiefer B, Macura KJ, Margolis DJA, Padhani AR, Selnæs KM, Villeirs GM, Fütterer JJ, Scheenen TWJ.

Invest Radiol. 2019 Jul;54(7):437-447. doi: 10.1097/RLI.0000000000000558.


Can we predict lesion detection rates in second-look ultrasound of MRI-detected breast lesions? A systematic analysis.

Bumberger A, Clauser P, Kolta M, Kapetas P, Bernathova M, Helbich TH, Pinker K, Baltzer PA.

Eur J Radiol. 2019 Apr;113:96-100. doi: 10.1016/j.ejrad.2019.02.008. Epub 2019 Feb 11.


Stand-Alone Artificial Intelligence for Breast Cancer Detection in Mammography: Comparison With 101 Radiologists.

Rodriguez-Ruiz A, Lång K, Gubern-Merida A, Broeders M, Gennaro G, Clauser P, Helbich TH, Chevalier M, Tan T, Mertelmeier T, Wallis MG, Andersson I, Zackrisson S, Mann RM, Sechopoulos I.

J Natl Cancer Inst. 2019 Sep 1;111(9):916-922. doi: 10.1093/jnci/djy222.


Diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) mapping as a quantitative imaging biomarker for prediction of immunohistochemical receptor status, proliferation rate, and molecular subtypes of breast cancer.

Horvat JV, Bernard-Davila B, Helbich TH, Zhang M, Morris EA, Thakur SB, Ochoa-Albiztegui RE, Leithner D, Marino MA, Baltzer PA, Clauser P, Kapetas P, Bago-Horvath Z, Pinker K.

J Magn Reson Imaging. 2019 Sep;50(3):836-846. doi: 10.1002/jmri.26697. Epub 2019 Feb 27.


Sequential [18F]FDG-[18F]FMISO PET and Multiparametric MRI at 3T for Insights into Breast Cancer Heterogeneity and Correlation with Patient Outcomes: First Clinical Experience.

Andrzejewski P, Wengert G, Helbich TH, Magometschnigg H, Georg D, Hacker M, Baltzer P, Clauser P, Kapetas P, Georg P, Wadsak W, Pinker K.

Contrast Media Mol Imaging. 2019 Jan 8;2019:1307247. doi: 10.1155/2019/1307247. eCollection 2019.


Quantitative Multiparametric Breast Ultrasound: Application of Contrast-Enhanced Ultrasound and Elastography Leads to an Improved Differentiation of Benign and Malignant Lesions.

Kapetas P, Clauser P, Woitek R, Wengert GJ, Lazar M, Pinker K, Helbich TH, Baltzer PAT.

Invest Radiol. 2019 May;54(5):257-264. doi: 10.1097/RLI.0000000000000543.


Breast lesion detection and characterization with contrast-enhanced magnetic resonance imaging: Prospective randomized intraindividual comparison of gadoterate meglumine (0.15 mmol/kg) and gadobenate dimeglumine (0.075 mmol/kg) at 3T.

Clauser P, Helbich TH, Kapetas P, Pinker K, Bernathova M, Woitek R, Kaneider A, Baltzer PAT.

J Magn Reson Imaging. 2019 Apr;49(4):1157-1165. doi: 10.1002/jmri.26335. Epub 2018 Dec 15.


Development of a Non-invasive Assessment of Hypoxia and Neovascularization with Magnetic Resonance Imaging in Benign and Malignant Breast Tumors: Initial Results.

Stadlbauer A, Zimmermann M, Bennani-Baiti B, Helbich TH, Baltzer P, Clauser P, Kapetas P, Bago-Horvath Z, Pinker K.

Mol Imaging Biol. 2019 Aug;21(4):758-770. doi: 10.1007/s11307-018-1298-4.


Multiparametric MRI model with dynamic contrast-enhanced and diffusion-weighted imaging enables breast cancer diagnosis with high accuracy.

Zhang M, Horvat JV, Bernard-Davila B, Marino MA, Leithner D, Ochoa-Albiztegui RE, Helbich TH, Morris EA, Thakur S, Pinker K.

J Magn Reson Imaging. 2019 Mar;49(3):864-874. doi: 10.1002/jmri.26285. Epub 2018 Oct 30.


Impact of Machine Learning With Multiparametric Magnetic Resonance Imaging of the Breast for Early Prediction of Response to Neoadjuvant Chemotherapy and Survival Outcomes in Breast Cancer Patients.

Tahmassebi A, Wengert GJ, Helbich TH, Bago-Horvath Z, Alaei S, Bartsch R, Dubsky P, Baltzer P, Clauser P, Kapetas P, Morris EA, Meyer-Baese A, Pinker K.

Invest Radiol. 2019 Feb;54(2):110-117. doi: 10.1097/RLI.0000000000000518.


Synthetic 2-Dimensional Mammography Can Replace Digital Mammography as an Adjunct to Wide-Angle Digital Breast Tomosynthesis.

Clauser P, Baltzer PAT, Kapetas P, Woitek R, Weber M, Leone F, Bernathova M, Helbich TH.

Invest Radiol. 2019 Feb;54(2):83-88. doi: 10.1097/RLI.0000000000000513.


Density and tailored breast cancer screening: practice and prediction - an overview.

Wengert GJ, Helbich TH, Kapetas P, Baltzer PA, Pinker K.

Acta Radiol Open. 2018 Sep 17;7(9):2058460118791212. doi: 10.1177/2058460118791212. eCollection 2018 Sep.


Abbreviated MRI of the Breast: Does It Provide Value?

Leithner D, Moy L, Morris EA, Marino MA, Helbich TH, Pinker K.

J Magn Reson Imaging. 2019 Jun;49(7):e85-e100. doi: 10.1002/jmri.26291. Epub 2018 Sep 8.


Imaging Phenotypes in Women at High Risk for Breast Cancer on Mammography, Ultrasound, and Magnetic Resonance Imaging Using the Fifth Edition of the Breast Imaging Reporting and Data System.

Marino MA, Riedl CC, Bernathova M, Bernhart C, Baltzer PAT, Helbich TH, Pinker K.

Eur J Radiol. 2018 Sep;106:150-159. doi: 10.1016/j.ejrad.2018.07.026. Epub 2018 Jul 30.


PSMA Ligand PET/MRI for Primary Prostate Cancer: Staging Performance and Clinical Impact.

Grubmüller B, Baltzer P, Hartenbach S, D'Andrea D, Helbich TH, Haug AR, Goldner GM, Wadsak W, Pfaff S, Mitterhauser M, Balber T, Berroteran-Infante N, Grahovac M, Babich J, Seitz C, Kramer G, Susani M, Mazal P, Kenner L, Shariat SF, Hacker M, Hartenbach M.

Clin Cancer Res. 2018 Dec 15;24(24):6300-6307. doi: 10.1158/1078-0432.CCR-18-0768. Epub 2018 Aug 23.


Breast ultrasound: recommendations for information to women and referring physicians by the European Society of Breast Imaging.

Evans A, Trimboli RM, Athanasiou A, Balleyguier C, Baltzer PA, Bick U, Camps Herrero J, Clauser P, Colin C, Cornford E, Fallenberg EM, Fuchsjaeger MH, Gilbert FJ, Helbich TH, Kinkel K, Heywang-Köbrunner SH, Kuhl CK, Mann RM, Martincich L, Panizza P, Pediconi F, Pijnappel RM, Pinker K, Zackrisson S, Forrai G, Sardanelli F; European Society of Breast Imaging (EUSOBI) , with language review by Europa Donna–The European Breast Cancer Coalition.

Insights Imaging. 2018 Aug;9(4):449-461. doi: 10.1007/s13244-018-0636-z. Epub 2018 Aug 9.


Density estimation of grey-level co-occurrence matrices for image texture analysis.

Garpebring A, Brynolfsson P, Kuess P, Georg D, Helbich TH, Nyholm T, Löfstedt T.

Phys Med Biol. 2018 Oct 2;63(19):195017. doi: 10.1088/1361-6560/aad8ec.


Quantitative Apparent Diffusion Coefficient Derived From Diffusion-Weighted Imaging Has the Potential to Avoid Unnecessary MRI-Guided Biopsies of mpMRI-Detected PI-RADS 4 and 5 Lesions.

Polanec SH, Helbich TH, Bickel H, Wengert GJ, Pinker K, Spick C, Clauser P, Susani M, Shariat S, Baltzer PAT.

Invest Radiol. 2018 Dec;53(12):736-741. doi: 10.1097/RLI.0000000000000498.


Imaging and the completion of the omics paradigm in breast cancer.

Leithner D, Horvat JV, Ochoa-Albiztegui RE, Thakur S, Wengert G, Morris EA, Helbich TH, Pinker K.

Radiologe. 2018 Nov;58(Suppl 1):7-13. doi: 10.1007/s00117-018-0409-1. Review.


MRI-based quantification of residual fibroglandular tissue of the breast after conservative mastectomies.

Woitek R, Pfeiler G, Farr A, Kapetas P, Furtner J, Bernathova M, Schöpf V, Clauser P, Marino MA, Pinker K, Baltzer PA, Helbich TH.

Eur J Radiol. 2018 Jul;104:1-7. doi: 10.1016/j.ejrad.2018.04.028. Epub 2018 Apr 26.


Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo.

Laszlo V, Valko Z, Kovacs I, Ozsvar J, Hoda MA, Klikovits T, Lakatos D, Czirok A, Garay T, Stiglbauer A, Helbich TH, Gröger M, Tovari J, Klepetko W, Pirker C, Grusch M, Berger W, Hilberg F, Hegedus B, Dome B.

Clin Cancer Res. 2018 Aug 1;24(15):3729-3740. doi: 10.1158/1078-0432.CCR-17-1507. Epub 2018 May 3.


A Simple Ultrasound Based Classification Algorithm Allows Differentiation of Benign from Malignant Breast Lesions by Using Only Quantitative Parameters.

Kapetas P, Woitek R, Clauser P, Bernathova M, Pinker K, Helbich TH, Baltzer PA.

Mol Imaging Biol. 2018 Dec;20(6):1053-1060. doi: 10.1007/s11307-018-1187-x.


Diffusion-Weighted Imaging With Apparent Diffusion Coefficient Mapping for Breast Cancer Detection as a Stand-Alone Parameter: Comparison With Dynamic Contrast-Enhanced and Multiparametric Magnetic Resonance Imaging.

Pinker K, Moy L, Sutton EJ, Mann RM, Weber M, Thakur SB, Jochelson MS, Bago-Horvath Z, Morris EA, Baltzer PA, Helbich TH.

Invest Radiol. 2018 Oct;53(10):587-595. doi: 10.1097/RLI.0000000000000465.


Virtual Touch IQ elastography reduces unnecessary breast biopsies by applying quantitative "rule-in" and "rule-out" threshold values.

Kapetas P, Clauser P, Woitek R, Pinker K, Bernathova M, Helbich TH, Baltzer PA.

Sci Rep. 2018 Feb 26;8(1):3583. doi: 10.1038/s41598-018-22065-7.


Clinical role of breast MRI now and going forward.

Leithner D, Wengert GJ, Helbich TH, Thakur S, Ochoa-Albiztegui RE, Morris EA, Pinker K.

Clin Radiol. 2018 Aug;73(8):700-714. doi: 10.1016/j.crad.2017.10.021. Epub 2017 Dec 9. Review.


Potential of Noncontrast Magnetic Resonance Imaging With Diffusion-Weighted Imaging in Characterization of Breast Lesions: Intraindividual Comparison With Dynamic Contrast-Enhanced Magnetic Resonance Imaging.

Baltzer PAT, Bickel H, Spick C, Wengert G, Woitek R, Kapetas P, Clauser P, Helbich TH, Pinker K.

Invest Radiol. 2018 Apr;53(4):229-235. doi: 10.1097/RLI.0000000000000433.


A survey by the European Society of Breast Imaging on the utilisation of breast MRI in clinical practice.

Clauser P, Mann R, Athanasiou A, Prosch H, Pinker K, Dietzel M, Helbich TH, Fuchsjäger M, Camps-Herrero J, Sardanelli F, Forrai G, Baltzer PAT.

Eur Radiol. 2018 May;28(5):1909-1918. doi: 10.1007/s00330-017-5121-4. Epub 2017 Nov 22.


Application of BI-RADS Descriptors in Contrast-Enhanced Dual-Energy Mammography: Comparison with MRI.

Knogler T, Homolka P, Hoernig M, Leithner R, Langs G, Waitzbauer M, Pinker K, Leitner S, Helbich TH.

Breast Care (Basel). 2017 Sep;12(4):212-216. doi: 10.1159/000478899. Epub 2017 Aug 17.


Erratum to "The breast lesion excision system (BLES) under stereotactic guidance cannot be used as a therapeutic tool in the excision of small areas of microcalcifications in the breast" [EURR 93C (2017) 252-257].

Milos RI, Bernathova M, Baltzer PA, Pinker-Domenig K, Kapetas P, Rudas M, Helbich TH.

Eur J Radiol. 2017 Nov;96:173. doi: 10.1016/j.ejrad.2017.07.019. Epub 2017 Oct 5. No abstract available.


Accuracy of screening women at familial risk of breast cancer without a known gene mutation: Individual patient data meta-analysis.

Phi XA, Houssami N, Hooning MJ, Riedl CC, Leach MO, Sardanelli F, Warner E, Trop I, Saadatmand S, Tilanus-Linthorst MMA, Helbich TH, van den Heuvel ER, de Koning HJ, Obdeijn IM, de Bock GH.

Eur J Cancer. 2017 Nov;85:31-38. doi: 10.1016/j.ejca.2017.07.055. Review.


Association between pathology and texture features of multi parametric MRI of the prostate.

Kuess P, Andrzejewski P, Nilsson D, Georg P, Knoth J, Susani M, Trygg J, Helbich TH, Polanec SH, Georg D, Nyholm T.

Phys Med Biol. 2017 Sep 21;62(19):7833-7854. doi: 10.1088/1361-6560/aa884d.


Multiparametric [11C]Acetate positron emission tomography-magnetic resonance imaging in the assessment and staging of prostate cancer.

Polanec SH, Andrzejewski P, Baltzer PAT, Helbich TH, Stiglbauer A, Georg D, Karanikas G, Susani M, Wadsak W, Margreiter M, Mitterhauser M, Brader P, Pinker K.

PLoS One. 2017 Jul 18;12(7):e0180790. doi: 10.1371/journal.pone.0180790. eCollection 2017.


The breast lesion excision system (BLES) under stereotactic guidance cannot be used as a therapeutic tool in the excision of small areas of microcalcifications in the breast.

Milos RI, Bernathova M, Baltzer PA, Pinker-Domenig K, Kapetas P, Rudas M, Helbich TH.

Eur J Radiol. 2017 Aug;93:252-257. doi: 10.1016/j.ejrad.2017.05.045. Epub 2017 Jun 2. Erratum in: Eur J Radiol. 2017 Nov;96:173.


Accuracy of fully automated, quantitative, volumetric measurement of the amount of fibroglandular breast tissue using MRI: correlation with anthropomorphic breast phantoms.

Wengert GJ, Pinker K, Helbich TH, Vogl WD, Spijker SM, Bickel H, Polanec SH, Baltzer PA.

NMR Biomed. 2017 Jun;30(6). doi: 10.1002/nbm.3705. Epub 2017 Mar 10.


A simple classification system (the Tree flowchart) for breast MRI can reduce the number of unnecessary biopsies in MRI-only lesions.

Woitek R, Spick C, Schernthaner M, Rudas M, Kapetas P, Bernathova M, Furtner J, Pinker K, Helbich TH, Baltzer PAT.

Eur Radiol. 2017 Sep;27(9):3799-3809. doi: 10.1007/s00330-017-4755-6. Epub 2017 Mar 8.


Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors.

Torok S, Rezeli M, Kelemen O, Vegvari A, Watanabe K, Sugihara Y, Tisza A, Marton T, Kovacs I, Tovari J, Laszlo V, Helbich TH, Hegedus B, Klikovits T, Hoda MA, Klepetko W, Paku S, Marko-Varga G, Dome B.

Theranostics. 2017 Jan 1;7(2):400-412. doi: 10.7150/thno.16767. eCollection 2017.


Mammography: an update of the EUSOBI recommendations on information for women.

Sardanelli F, Fallenberg EM, Clauser P, Trimboli RM, Camps-Herrero J, Helbich TH, Forrai G; European Society of Breast Imaging (EUSOBI), with language review by Europa Donna–The European Breast Cancer Coalition.

Insights Imaging. 2017 Feb;8(1):11-18. doi: 10.1007/s13244-016-0531-4. Epub 2016 Nov 16.


Diagnostic performance of digital breast tomosynthesis with a wide scan angle compared to full-field digital mammography for the detection and characterization of microcalcifications.

Clauser P, Nagl G, Helbich TH, Pinker-Domenig K, Weber M, Kapetas P, Bernathova M, Baltzer PAT.

Eur J Radiol. 2016 Dec;85(12):2161-2168. doi: 10.1016/j.ejrad.2016.10.004. Epub 2016 Oct 7.


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