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Items: 1 to 50 of 165

1.

Daratumumab-225Actinium conjugate demonstrates greatly enhanced antitumor activity against experimental multiple myeloma tumors.

Dawicki W, Allen KJH, Jiao R, Malo ME, Helal M, Berger MS, Ludwig DL, Dadachova E.

Oncoimmunology. 2019 May 1;8(8):1607673. doi: 10.1080/2162402X.2019.1607673. eCollection 2019.

2.

Detection and targeting insulin growth factor receptor type 2 (IGF2R) in osteosarcoma PDX in mouse models and in canine osteosarcoma tumors.

Karkare S, Allen KJH, Jiao R, Malo ME, Dawicki W, Helal M, Godson DL, Dickinson R, MacDonald-Dickinson V, Yang R, Hoang B, Gorlick R, Geller DS, Dadachova E.

Sci Rep. 2019 Aug 7;9(1):11476. doi: 10.1038/s41598-019-47808-y.

3.

Design and Synthesis of Imidazole and Triazole Pyrazoles as Mycobacterium Tuberculosis CYP121A1 Inhibitors.

Kishk SM, McLean KJ, Sood S, Smith D, Evans JWD, Helal MA, Gomaa MS, Salama I, Mostafa SM, de Carvalho LPS, Levy CW, Munro AW, Simons C.

ChemistryOpen. 2019 Jul 23;8(7):995-1011. doi: 10.1002/open.201900227. eCollection 2019 Jul.

4.

Integrated continuous manufacturing in pharmaceutical industry: current evolutionary steps toward revolutionary future.

Helal NA, Elnoweam O, Eassa HA, Amer AM, Eltokhy MA, Helal MA, Fayyaz HA, Nounou MI.

Pharm Pat Anal. 2019 Jul;8(4):139-161. doi: 10.4155/ppa-2019-0011. Epub 2019 Jul 29.

PMID:
31354057
5.

Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer.

Jiao R, Allen KJH, Malo ME, Helal M, Jiang Z, Smart K, Buhl SV, Rickles D, Bryan RA, Dadachova E.

Cancer Med. 2019 Sep;8(11):5289-5300. doi: 10.1002/cam4.2379. Epub 2019 Jul 16.

6.

The role of contrast-enhanced spectral mammography in the evaluation of the postoperative breast cancer.

Helal MH, Mansour SM, Ahmed HA, Abdel Ghany AF, Kamel OF, Elkholy NG.

Clin Radiol. 2019 Oct;74(10):771-781. doi: 10.1016/j.crad.2019.06.002. Epub 2019 Jul 6.

PMID:
31285035
7.

16q22.1 microdeletion and anticipatory guidance.

Abdullah S, Helal M, Dupuis L, Stavropoulos DJ, Louro P, Ramos L, Mendoza-Londono R.

Am J Med Genet A. 2019 Jul;179(7):1287-1292. doi: 10.1002/ajmg.a.61155. Epub 2019 May 29.

PMID:
31141312
8.

Optimization of Bacillus licheniformis MAL tyrosinase: in vitro anticancer activity for brown and black eumelanin.

Gamal Shalaby AS, Ragab TIM, Helal MMI, Esawy MA.

Heliyon. 2019 May 8;5(5):e01657. doi: 10.1016/j.heliyon.2019.e01657. eCollection 2019 May.

9.

Reactivation of herpesvirus in patients with hepatitis C treated with direct-acting antiviral agents.

Ghweil AA, Helal MM.

Infect Drug Resist. 2019 Apr 2;12:759-762. doi: 10.2147/IDR.S184598. eCollection 2019.

10.

Silymarin and silymarin nanoparticles guard against chronic unpredictable mild stress induced depressive-like behavior in mice: involvement of neurogenesis and NLRP3 inflammasome.

Ashraf A, Mahmoud PA, Reda H, Mansour S, Helal MH, Michel HE, Nasr M.

J Psychopharmacol. 2019 May;33(5):615-631. doi: 10.1177/0269881119836221. Epub 2019 Mar 21.

PMID:
30896354
11.

Synthesis and biological evaluation of novel cYY analogues targeting Mycobacterium tuberculosis CYP121A1.

Kishk SM, McLean KJ, Sood S, Helal MA, Gomaa MS, Salama I, Mostafa SM, de Carvalho LPS, Munro AW, Simons C.

Bioorg Med Chem. 2019 Apr 15;27(8):1546-1561. doi: 10.1016/j.bmc.2019.02.051. Epub 2019 Feb 27.

12.

Development and validation of an HPLC-UV method for simultaneous determination of sildenafil and tramadol in biological fluids: Application to drug-drug interaction study.

Dahshan HE, Helal MA, Mostafa SM, Elgawish MS.

J Pharm Biomed Anal. 2019 May 10;168:201-208. doi: 10.1016/j.jpba.2019.02.025. Epub 2019 Feb 19.

PMID:
30825803
13.

Carvedilol attenuates experimentally induced silicosis in rats via modulation of P-AKT/mTOR/TGFβ1 signaling.

Helal MG, Said E.

Int Immunopharmacol. 2019 May;70:47-55. doi: 10.1016/j.intimp.2019.02.011. Epub 2019 Feb 20.

PMID:
30785090
14.

Healing Capacity of Autologous Bone Marrow-derived Mesenchymal Stem Cells on Partially Pulpotomized Dogs' Teeth.

El-Zekrid MH, Mahmoud SH, Ali FA, Helal ME, Grawish ME.

J Endod. 2019 Mar;45(3):287-294. doi: 10.1016/j.joen.2018.11.013. Epub 2019 Feb 2.

PMID:
30722983
15.

Oncostatic treatment effect of triple negative breast cancer cell line with copper (I)-nicotinate complex.

Abdel-Mohsen MA, Toson EA, Helal MA.

J Cell Biochem. 2019 Mar;120(3):4278-4290. doi: 10.1002/jcb.27713. Epub 2018 Oct 26.

PMID:
30362603
16.

Clinical Management Protocol for Dental Implants Inserted in Patients with Active Lichen Planus. Part II 4-Year Follow-Up.

Khamis AK, Aboushelib MN, Helal MH.

J Prosthodont. 2019 Jun;28(5):519-525. doi: 10.1111/jopr.12993. Epub 2018 Nov 14.

PMID:
30357978
17.

Seroprevalence of dengue fever and the associated sociodemographic, clinical, and environmental factors in Makkah, Madinah, Jeddah, and Jizan, Kingdom of Saudi Arabia.

Al-Raddadi R, Alwafi O, Shabouni O, Akbar N, Alkhalawi M, Ibrahim A, Hussain R, Alzahrani M, Al Helal M, Assiri A.

Acta Trop. 2019 Jan;189:54-64. doi: 10.1016/j.actatropica.2018.09.009. Epub 2018 Sep 20.

PMID:
30244133
18.

Radioimmunotherapy as a Novel Approach in HIV, Bacterial, and Fungal Infectious Diseases.

Helal M, Dadachova E.

Cancer Biother Radiopharm. 2018 Oct;33(8):330-335. doi: 10.1089/cbr.2018.2481. Epub 2018 Aug 22. Review.

PMID:
30133305
19.

Clinical presentation and natural history of infantile-onset ascending spastic paralysis from three families with an ALS2 founder variant.

Helal M, Mazaheri N, Shalbafan B, Malamiri RA, Dilaver N, Buchert R, Mohammadiasl J, Golchin N, Sedaghat A, Mehrjardi MYV, Haack TB, Riess O, Chung WK, Galehdari H, Shariati G, Maroofian R.

Neurol Sci. 2018 Nov;39(11):1917-1925. doi: 10.1007/s10072-018-3526-8. Epub 2018 Aug 21.

PMID:
30128655
20.

Stability analysis of a steady state of a model describing Alzheimer's disease and interactions with prion proteins.

Helal M, Igel-Egalon A, Lakmeche A, Mazzocco P, Perrillat-Mercerot A, Pujo-Menjouet L, Rezaei H, Tine LM.

J Math Biol. 2019 Jan;78(1-2):57-81. doi: 10.1007/s00285-018-1267-1. Epub 2018 Aug 11.

21.

Nephroprotective effect of saxagliptin against gentamicin-induced nephrotoxicity, emphasis on anti-oxidant, anti-inflammatory and anti-apoptic effects.

Helal MG, Zaki MMAF, Said E.

Life Sci. 2018 Sep 1;208:64-71. doi: 10.1016/j.lfs.2018.07.021. Epub 2018 Jul 17.

PMID:
30012474
22.

Osteogenesis ability of CAD-CAM biodegradable polylactic acid scaffolds for reconstruction of jaw defects.

Helal MH, Hendawy HD, Gaber RA, Helal NR, Aboushelib MN.

J Prosthet Dent. 2019 Jan;121(1):118-123. doi: 10.1016/j.prosdent.2018.03.033. Epub 2018 Jun 29.

PMID:
29961633
23.

Clinical, behavioral and biochemical alterations due to shearing stress in Ossimi sheep.

Hefnawy A, Helal MAY, Sabek A, Shousha S.

J Vet Med Sci. 2018 Aug 22;80(8):1281-1286. doi: 10.1292/jvms.18-0150. Epub 2018 Jun 25.

24.

Gelfoam haemostatic agent with or without autologous bone marrow-derived stem cells for the regeneration of critical-size mandibular defects in the rabbit.

Ashour AA, Zaghloul M, Mahmoud W, Helal ME, Grawish ME.

Int J Oral Maxillofac Surg. 2018 Nov;47(11):1488-1494. doi: 10.1016/j.ijom.2018.04.021. Epub 2018 May 9.

PMID:
29753427
25.

The impact of contrast-enhanced spectral mammogram (CESM) and three-dimensional breast ultrasound (3DUS) on the characterization of the disease extend in cancer patients.

Helal MH, Mansour SM, Salaleldin LA, Alkalaawy BM, Salem DS, Mokhtar NM.

Br J Radiol. 2018 Jul;91(1087):20170977. doi: 10.1259/bjr.20170977. Epub 2018 May 24.

26.

Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-γ/FFAR1 agonists.

Darwish KM, Salama I, Mostafa S, Gomaa MS, Khafagy ES, Helal MA.

Bioorg Med Chem Lett. 2018 May 15;28(9):1595-1602. doi: 10.1016/j.bmcl.2018.03.051. Epub 2018 Mar 21.

PMID:
29615345
27.

Photocatalytic degradation of phenazopyridine contaminant in soil with direct solar light.

Zyoud A, Ateeq M, Helal MH, Zyoud SH, Hilal HS.

Environ Technol. 2019 Sep;40(22):2928-2939. doi: 10.1080/09593330.2018.1459873. Epub 2018 Apr 9.

PMID:
29600741
28.

Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides.

Boslett J, Helal M, Chini E, Zweier JL.

J Mol Cell Cardiol. 2018 May;118:81-94. doi: 10.1016/j.yjmcc.2018.02.015. Epub 2018 Feb 21.

29.

Caffeine affects HFD-induced hepatic steatosis by multifactorial intervention.

Helal MG, Ayoub SE, Elkashefand WF, Ibrahim TM.

Hum Exp Toxicol. 2018 Sep;37(9):983-990. doi: 10.1177/0960327117747026. Epub 2017 Dec 18.

PMID:
29249184
30.

Selective kappa opioid antagonists for treatment of addiction, are we there yet?

Helal MA, Habib ES, Chittiboyina AG.

Eur J Med Chem. 2017 Dec 1;141:632-647. doi: 10.1016/j.ejmech.2017.10.012. Epub 2017 Oct 10. Review.

PMID:
29107424
31.
32.

Effects of aqueous cinnamon extract on chemically-induced carcinoma of hamster cheek pouch mucosa.

Ezzat SK, AbuElkhair MT, Mourad MI, Helal ME, Grawish ME.

Biochem Biophys Rep. 2017 Sep 1;12:72-78. doi: 10.1016/j.bbrep.2017.08.014. eCollection 2017 Dec.

33.

Electric field and aging effects of uniaxial ferroelectrics Sr x Ba1-x Nb2O6 probed by Brillouin scattering.

Aftabuzzaman M, Helal MA, Paszkowski R, Dec J, Kleemann W, Kojima S.

Sci Rep. 2017 Sep 14;7(1):11615. doi: 10.1038/s41598-017-10985-9.

34.

2D Ti3C2Tx (MXene)-reinforced polyvinyl alcohol (PVA) nanofibers with enhanced mechanical and electrical properties.

Sobolčiak P, Ali A, Hassan MK, Helal MI, Tanvir A, Popelka A, Al-Maadeed MA, Krupa I, Mahmoud KA.

PLoS One. 2017 Aug 30;12(8):e0183705. doi: 10.1371/journal.pone.0183705. eCollection 2017.

35.

Regenerative capacity of allogenic gingival margin- derived stem cells with fibrin glue on albino rats' partially dissected submandibular salivary glands.

Abd El-Latif N, Abdulrahman M, Helal M, Grawish ME.

Arch Oral Biol. 2017 Oct;82:302-309. doi: 10.1016/j.archoralbio.2017.06.030. Epub 2017 Jun 27.

PMID:
28688332
36.

Impact of Autologous Bone Marrow-Derived Stem Cells on Degenerative Changes of Articulating Surfaces Associated With the Arthritic Temporomandibular Joint: An Experimental Study in Rabbits.

Zaki AA, Zaghloul M, Helal ME, Mansour NA, Grawish ME.

J Oral Maxillofac Surg. 2017 Dec;75(12):2529-2539. doi: 10.1016/j.joms.2017.05.001. Epub 2017 May 10.

PMID:
28576669
37.

Efficient Antibacterial Membrane based on Two-Dimensional Ti3C2Tx (MXene) Nanosheets.

Rasool K, Mahmoud KA, Johnson DJ, Helal M, Berdiyorov GR, Gogotsi Y.

Sci Rep. 2017 May 9;7(1):1598. doi: 10.1038/s41598-017-01714-3.

38.

Novel pyrazoles and pyrazolo[1,2-a]pyridazines as selective COX-2 inhibitors; Ultrasound-assisted synthesis, biological evaluation, and DFT calculations.

Ghareb N, Elshihawy HA, Abdel-Daim MM, Helal MA.

Bioorg Med Chem Lett. 2017 Jun 1;27(11):2377-2383. doi: 10.1016/j.bmcl.2017.04.020. Epub 2017 Apr 8.

PMID:
28427813
39.

Role of polar nanoregions with weak random fields in Pb-based perovskite ferroelectrics.

Helal MA, Aftabuzzaman M, Tsukada S, Kojima S.

Sci Rep. 2017 Mar 16;7:44448. doi: 10.1038/srep44448.

40.

Efficacy of Human Platelet Rich Fibrin Exudate vs Fetal Bovine Serum on Proliferation and Differentiation of Dental Pulp Stem Cells.

Saeed MA, El-Rahman MA, Helal ME, Zaher AR, Grawish ME.

Int J Stem Cells. 2017 May 30;10(1):38-47. doi: 10.15283/ijsc16067.

41.

Staging of breast cancer and the advanced applications of digital mammogram: what the physician needs to know?

Helal MH, Mansour SM, Zaglol M, Salaleldin LA, Nada OM, Haggag MA.

Br J Radiol. 2017 Mar;90(1071):20160717. doi: 10.1259/bjr.20160717. Epub 2017 Feb 22.

42.

Efficacy of azithromycin and metronidazole combined therapy on rats' gingival overgrowth induced by cyclosporine-A: An experimental animal study.

Elkabir MA, El-Zehery RR, Mourad MI, Soliman O, Helal ME, Refai AK, Grawish ME.

J Oral Biol Craniofac Res. 2016 Sep-Dec;6(3):219-226. Epub 2016 Apr 5.

43.

Immunomodulatory capacity of the local mesenchymal stem cells transplantation after severe skeletal muscle injury in female rats.

Helal MAM, Shaheen NEM, Abu Zahra FA.

Immunopharmacol Immunotoxicol. 2016 Dec;38(6):414-422. doi: 10.1080/08923973.2016.1222617. Epub 2016 Aug 25.

PMID:
27560658
44.

Enzymatic synthesis using immobilized Enterococcus faecalis Esawy dextransucrase and some applied studies.

Esawy MA, Gamal AA, Helal MM, Hassan ME, Hassanein NM, Hashem AM.

Int J Biol Macromol. 2016 Nov;92:56-62. doi: 10.1016/j.ijbiomac.2016.06.041. Epub 2016 Jun 17.

PMID:
27327909
45.

Can we apply the MRI BI-RADS lexicon morphology descriptors on contrast-enhanced spectral mammography?

Kamal RM, Helal MH, Mansour SM, Haggag MA, Nada OM, Farahat IG, Alieldin NH.

Br J Radiol. 2016 Aug;89(1064):20160157. doi: 10.1259/bjr.20160157. Epub 2016 Jun 21.

46.

Targeted study to evaluate the cardiovascular risk factor status among patients and efficacy of statins in attaining goal lipid levels in a regional hospital in Sultanate of Oman.

Jose J, Al-Tamimi FA, Helal MM, Jimmy B, Al Riyami Q, Al Busaidi I.

Saudi Pharm J. 2015 Sep;23(4):371-6. doi: 10.1016/j.jsps.2014.11.006. Epub 2014 Nov 24.

47.

Prenatal effects of transplacental exposure to ifosfamide in rats.

Helal M.

Biotech Histochem. 2016 Jul;91(5):357-68. doi: 10.1080/10520295.2016.1176253. Epub 2016 Apr 28.

PMID:
27124550
48.

Correlation between Serum Hyaluronic Acid with Steatosis, Non alcoholic Steato-hepatitis and Fibrosis in Patients with Chronic Hepatitis C Virus Infection.

Mahmoud HS, Ghweil AAS, Osman GS, Ezz-Eldin S Bazeed S, Helal MM.

Trop Gastroenterol. 2016 Apr-Jun;37(2):93-100.

PMID:
30234278
49.

Synthesis and structure elucidation of some novel thiophene and benzothiophene derivatives as cytotoxic agents.

Mohareb RM, Abdallah AE, Helal MH, Shaloof SM.

Acta Pharm. 2016 Mar;66(1):53-68. doi: 10.1515/acph-2016-0005.

PMID:
26959543
50.

Antibacterial Activity of Ti₃C₂Tx MXene.

Rasool K, Helal M, Ali A, Ren CE, Gogotsi Y, Mahmoud KA.

ACS Nano. 2016 Mar 22;10(3):3674-84. doi: 10.1021/acsnano.6b00181. Epub 2016 Mar 1.

PMID:
26909865

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