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Items: 1 to 50 of 182

1.

Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures.

Tan TY, Sedmík J, Fitzgerald MP, Halevy RS, Keegan LP, Helbig I, Basel-Salmon L, Cohen L, Straussberg R, Chung WK, Helal M, Maroofian R, Houlden H, Juusola J, Sadedin S, Pais L, Howell KB, White SM, Christodoulou J, O'Connell MA.

Am J Hum Genet. 2020 Apr 2;106(4):467-483. doi: 10.1016/j.ajhg.2020.02.015. Epub 2020 Mar 26.

PMID:
32220291
2.
3.

Radioimmunotherapy of Blastomycosis in a Mouse Model With a (1→3)-β-Glucans Targeting Antibody.

Helal M, Allen KJH, van Dijk B, Nosanchuk JD, Snead E, Dadachova E.

Front Microbiol. 2020 Feb 7;11:147. doi: 10.3389/fmicb.2020.00147. eCollection 2020.

4.

Early therapeutic effect of platelet-rich fibrin combined with allogeneic bone marrow-derived stem cells on rats' critical-sized mandibular defects.

Awadeen MA, Al-Belasy FA, Ameen LE, Helal ME, Grawish ME.

World J Stem Cells. 2020 Jan 26;12(1):55-69. doi: 10.4252/wjsc.v12.i1.55.

5.

Sugar Alcohols Have a Key Role in Pathogenesis of Chronic Liver Disease and Hepatocellular Carcinoma in Whole Blood and Liver Tissues.

Ismail IT, Fiehn O, Elfert A, Helal M, Salama I, El-Said H.

Cancers (Basel). 2020 Feb 19;12(2). pii: E484. doi: 10.3390/cancers12020484.

6.

Impact of different surface treatments and repair material reinforcement on the flexural strength of repaired PMMA denture base material.

Gad MM, Rahoma A, Abualsaud R, Al-Thobity AM, Akhtar S, Helal MA, Al-Harbi FA.

Dent Mater J. 2020 Feb 21. doi: 10.4012/dmj.2018-436. [Epub ahead of print]

7.

A recessive high-density pod mutant resource of Brassica napus.

Tang M, Tong C, Liang L, Du C, Zhao J, Xiao L, Tong J, Dai X, Helal M, Dai W, Xiang Y.

Plant Sci. 2020 Apr;293:110411. doi: 10.1016/j.plantsci.2020.110411. Epub 2020 Jan 15.

PMID:
32081260
8.

Tranilast attenuates methotrexate-induced renal and hepatic toxicities: Role of apoptosis-induced tissue proliferation.

Helal MG, Said E.

J Biochem Mol Toxicol. 2020 Feb 11:e22466. doi: 10.1002/jbt.22466. [Epub ahead of print]

PMID:
32045101
9.

Irbesartan mitigates acute liver injury, oxidative stress, and apoptosis induced by acetaminophen in mice.

Helal MG, Samra YA.

J Biochem Mol Toxicol. 2020 Jan 22:e22447. doi: 10.1002/jbt.22447. [Epub ahead of print]

PMID:
31967706
10.

Performance evaluation of various individual and mixed media for greywater treatment in vertical nature-based systems.

Pradhan S, Helal MI, Al-Ghamdi SG, Mackey HR.

Chemosphere. 2020 Apr;245:125564. doi: 10.1016/j.chemosphere.2019.125564. Epub 2019 Dec 11.

PMID:
31883500
11.

The impacts of seasonal variation on the immune status of Nile tilapia larvae and their response to different immunostimulants feed additives.

Elkatatny NM, El Nahas AF, Helal MA, Fahmy HA, Tanekhy M.

Fish Shellfish Immunol. 2020 Jan;96:270-278. doi: 10.1016/j.fsi.2019.12.027. Epub 2019 Dec 9.

PMID:
31830565
12.

Krill oil alleviates oxidative stress, iron accumulation and fibrosis in the liver and spleen of iron-overload rats.

Helal MG, El-Kashef DH.

Environ Sci Pollut Res Int. 2020 Feb;27(4):3950-3961. doi: 10.1007/s11356-019-06983-1. Epub 2019 Dec 10.

PMID:
31823254
13.

Cecal Volvulus in a child with congenital dilated cardiomyopathy: A case report.

Shehata AE, Helal MA, Ibrahim EA, Magdy B, El Seoudy M, Shaban M, Taher H.

Int J Surg Case Rep. 2020;66:30-32. doi: 10.1016/j.ijscr.2019.10.008. Epub 2019 Nov 23.

14.

Tracing Worldwide Turkey Genetic Diversity Using D-loop Sequence Mitochondrial DNA Analysis.

Canales Vergara AM, Landi V, Delgado Bermejo JV, Martínez A, Cervantes Acosta P, Pons Barro Á, Bigi D, Sponenberg P, Helal M, Hossein Banabazi M, Camacho Vallejo ME.

Animals (Basel). 2019 Nov 1;9(11). pii: E897. doi: 10.3390/ani9110897.

15.

Saxagliptin mitigates airway inflammation in a mouse model of acute asthma via modulation of NF-kB and TLR4.

Helal MG, Megahed NA, Abd Elhameed AG.

Life Sci. 2019 Dec 15;239:117017. doi: 10.1016/j.lfs.2019.117017. Epub 2019 Oct 31.

PMID:
31678284
16.

Identification of a new small molecule chemotype of Melanin Concentrating Hormone Receptor-1 antagonists using pharmacophore-based virtual screening.

Helal MA, Chittiboyina AG, Avery MA.

Bioorg Med Chem Lett. 2019 Dec 15;29(24):126741. doi: 10.1016/j.bmcl.2019.126741. Epub 2019 Oct 16.

PMID:
31678007
17.

Pyridine azo disperse dye derivatives and their selenium nanoparticles (SeNPs): synthesis, fastness properties, and antimicrobial evaluations.

Alnassar HS, Helal MH, Askar AA, Masoud DM, Abdallah AE.

Int J Nanomedicine. 2019 Sep 27;14:7903-7918. doi: 10.2147/IJN.S216914. eCollection 2019.

18.

Daratumumab-225Actinium conjugate demonstrates greatly enhanced antitumor activity against experimental multiple myeloma tumors.

Dawicki W, Allen KJH, Jiao R, Malo ME, Helal M, Berger MS, Ludwig DL, Dadachova E.

Oncoimmunology. 2019 May 1;8(8):1607673. doi: 10.1080/2162402X.2019.1607673. eCollection 2019.

19.

Detection and targeting insulin growth factor receptor type 2 (IGF2R) in osteosarcoma PDX in mouse models and in canine osteosarcoma tumors.

Karkare S, Allen KJH, Jiao R, Malo ME, Dawicki W, Helal M, Godson DL, Dickinson R, MacDonald-Dickinson V, Yang R, Hoang B, Gorlick R, Geller DS, Dadachova E.

Sci Rep. 2019 Aug 7;9(1):11476. doi: 10.1038/s41598-019-47808-y.

20.

Design and Synthesis of Imidazole and Triazole Pyrazoles as Mycobacterium Tuberculosis CYP121A1 Inhibitors.

Kishk SM, McLean KJ, Sood S, Smith D, Evans JWD, Helal MA, Gomaa MS, Salama I, Mostafa SM, de Carvalho LPS, Levy CW, Munro AW, Simons C.

ChemistryOpen. 2019 Jul 23;8(7):995-1011. doi: 10.1002/open.201900227. eCollection 2019 Jul.

21.

Integrated continuous manufacturing in pharmaceutical industry: current evolutionary steps toward revolutionary future.

Helal NA, Elnoweam O, Eassa HA, Amer AM, Eltokhy MA, Helal MA, Fayyaz HA, Nounou MI.

Pharm Pat Anal. 2019 Jul;8(4):139-161. doi: 10.4155/ppa-2019-0011. Epub 2019 Jul 29. Review.

PMID:
31354057
22.

Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer.

Jiao R, Allen KJH, Malo ME, Helal M, Jiang Z, Smart K, Buhl SV, Rickles D, Bryan RA, Dadachova E.

Cancer Med. 2019 Sep;8(11):5289-5300. doi: 10.1002/cam4.2379. Epub 2019 Jul 16.

23.

The role of contrast-enhanced spectral mammography in the evaluation of the postoperative breast cancer.

Helal MH, Mansour SM, Ahmed HA, Abdel Ghany AF, Kamel OF, Elkholy NG.

Clin Radiol. 2019 Oct;74(10):771-781. doi: 10.1016/j.crad.2019.06.002. Epub 2019 Jul 6.

PMID:
31285035
24.

16q22.1 microdeletion and anticipatory guidance.

Abdullah S, Helal M, Dupuis L, Stavropoulos DJ, Louro P, Ramos L, Mendoza-Londono R.

Am J Med Genet A. 2019 Jul;179(7):1287-1292. doi: 10.1002/ajmg.a.61155. Epub 2019 May 29.

PMID:
31141312
25.

Optimization of Bacillus licheniformis MAL tyrosinase: in vitro anticancer activity for brown and black eumelanin.

Gamal Shalaby AS, Ragab TIM, Helal MMI, Esawy MA.

Heliyon. 2019 May 8;5(5):e01657. doi: 10.1016/j.heliyon.2019.e01657. eCollection 2019 May.

26.

Reactivation of herpesvirus in patients with hepatitis C treated with direct-acting antiviral agents.

Ghweil AA, Helal MM.

Infect Drug Resist. 2019 Apr 2;12:759-762. doi: 10.2147/IDR.S184598. eCollection 2019.

27.

Silymarin and silymarin nanoparticles guard against chronic unpredictable mild stress induced depressive-like behavior in mice: involvement of neurogenesis and NLRP3 inflammasome.

Ashraf A, Mahmoud PA, Reda H, Mansour S, Helal MH, Michel HE, Nasr M.

J Psychopharmacol. 2019 May;33(5):615-631. doi: 10.1177/0269881119836221. Epub 2019 Mar 21.

PMID:
30896354
28.

Synthesis and biological evaluation of novel cYY analogues targeting Mycobacterium tuberculosis CYP121A1.

Kishk SM, McLean KJ, Sood S, Helal MA, Gomaa MS, Salama I, Mostafa SM, de Carvalho LPS, Munro AW, Simons C.

Bioorg Med Chem. 2019 Apr 15;27(8):1546-1561. doi: 10.1016/j.bmc.2019.02.051. Epub 2019 Feb 27.

29.

Development and validation of an HPLC-UV method for simultaneous determination of sildenafil and tramadol in biological fluids: Application to drug-drug interaction study.

Dahshan HE, Helal MA, Mostafa SM, Elgawish MS.

J Pharm Biomed Anal. 2019 May 10;168:201-208. doi: 10.1016/j.jpba.2019.02.025. Epub 2019 Feb 19.

PMID:
30825803
30.

Carvedilol attenuates experimentally induced silicosis in rats via modulation of P-AKT/mTOR/TGFβ1 signaling.

Helal MG, Said E.

Int Immunopharmacol. 2019 May;70:47-55. doi: 10.1016/j.intimp.2019.02.011. Epub 2019 Feb 20.

PMID:
30785090
31.

Healing Capacity of Autologous Bone Marrow-derived Mesenchymal Stem Cells on Partially Pulpotomized Dogs' Teeth.

El-Zekrid MH, Mahmoud SH, Ali FA, Helal ME, Grawish ME.

J Endod. 2019 Mar;45(3):287-294. doi: 10.1016/j.joen.2018.11.013. Epub 2019 Feb 2.

PMID:
30722983
32.

Oncostatic treatment effect of triple negative breast cancer cell line with copper (I)-nicotinate complex.

Abdel-Mohsen MA, Toson EA, Helal MA.

J Cell Biochem. 2019 Mar;120(3):4278-4290. doi: 10.1002/jcb.27713. Epub 2018 Oct 26.

PMID:
30362603
33.

Clinical Management Protocol for Dental Implants Inserted in Patients with Active Lichen Planus. Part II 4-Year Follow-Up.

Khamis AK, Aboushelib MN, Helal MH.

J Prosthodont. 2019 Jun;28(5):519-525. doi: 10.1111/jopr.12993. Epub 2018 Nov 14.

PMID:
30357978
34.

Seroprevalence of dengue fever and the associated sociodemographic, clinical, and environmental factors in Makkah, Madinah, Jeddah, and Jizan, Kingdom of Saudi Arabia.

Al-Raddadi R, Alwafi O, Shabouni O, Akbar N, Alkhalawi M, Ibrahim A, Hussain R, Alzahrani M, Al Helal M, Assiri A.

Acta Trop. 2019 Jan;189:54-64. doi: 10.1016/j.actatropica.2018.09.009. Epub 2018 Sep 20.

PMID:
30244133
35.

Radioimmunotherapy as a Novel Approach in HIV, Bacterial, and Fungal Infectious Diseases.

Helal M, Dadachova E.

Cancer Biother Radiopharm. 2018 Oct;33(8):330-335. doi: 10.1089/cbr.2018.2481. Epub 2018 Aug 22. Review.

36.

Clinical presentation and natural history of infantile-onset ascending spastic paralysis from three families with an ALS2 founder variant.

Helal M, Mazaheri N, Shalbafan B, Malamiri RA, Dilaver N, Buchert R, Mohammadiasl J, Golchin N, Sedaghat A, Mehrjardi MYV, Haack TB, Riess O, Chung WK, Galehdari H, Shariati G, Maroofian R.

Neurol Sci. 2018 Nov;39(11):1917-1925. doi: 10.1007/s10072-018-3526-8. Epub 2018 Aug 21.

PMID:
30128655
37.

Stability analysis of a steady state of a model describing Alzheimer's disease and interactions with prion proteins.

Helal M, Igel-Egalon A, Lakmeche A, Mazzocco P, Perrillat-Mercerot A, Pujo-Menjouet L, Rezaei H, Tine LM.

J Math Biol. 2019 Jan;78(1-2):57-81. doi: 10.1007/s00285-018-1267-1. Epub 2018 Aug 11.

38.

Nephroprotective effect of saxagliptin against gentamicin-induced nephrotoxicity, emphasis on anti-oxidant, anti-inflammatory and anti-apoptic effects.

Helal MG, Zaki MMAF, Said E.

Life Sci. 2018 Sep 1;208:64-71. doi: 10.1016/j.lfs.2018.07.021. Epub 2018 Jul 17.

PMID:
30012474
39.

Osteogenesis ability of CAD-CAM biodegradable polylactic acid scaffolds for reconstruction of jaw defects.

Helal MH, Hendawy HD, Gaber RA, Helal NR, Aboushelib MN.

J Prosthet Dent. 2019 Jan;121(1):118-123. doi: 10.1016/j.prosdent.2018.03.033. Epub 2018 Jun 29.

PMID:
29961633
40.

Clinical, behavioral and biochemical alterations due to shearing stress in Ossimi sheep.

Hefnawy A, Helal MAY, Sabek A, Shousha S.

J Vet Med Sci. 2018 Aug 22;80(8):1281-1286. doi: 10.1292/jvms.18-0150. Epub 2018 Jun 25.

41.

Gelfoam haemostatic agent with or without autologous bone marrow-derived stem cells for the regeneration of critical-size mandibular defects in the rabbit.

Ashour AA, Zaghloul M, Mahmoud W, Helal ME, Grawish ME.

Int J Oral Maxillofac Surg. 2018 Nov;47(11):1488-1494. doi: 10.1016/j.ijom.2018.04.021. Epub 2018 May 9.

PMID:
29753427
42.

The impact of contrast-enhanced spectral mammogram (CESM) and three-dimensional breast ultrasound (3DUS) on the characterization of the disease extend in cancer patients.

Helal MH, Mansour SM, Salaleldin LA, Alkalaawy BM, Salem DS, Mokhtar NM.

Br J Radiol. 2018 Jul;91(1087):20170977. doi: 10.1259/bjr.20170977. Epub 2018 May 24.

43.

Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-γ/FFAR1 agonists.

Darwish KM, Salama I, Mostafa S, Gomaa MS, Khafagy ES, Helal MA.

Bioorg Med Chem Lett. 2018 May 15;28(9):1595-1602. doi: 10.1016/j.bmcl.2018.03.051. Epub 2018 Mar 21.

PMID:
29615345
44.

Photocatalytic degradation of phenazopyridine contaminant in soil with direct solar light.

Zyoud A, Ateeq M, Helal MH, Zyoud SH, Hilal HS.

Environ Technol. 2019 Sep;40(22):2928-2939. doi: 10.1080/09593330.2018.1459873. Epub 2018 Apr 9.

PMID:
29600741
45.

Genetic deletion of CD38 confers post-ischemic myocardial protection through preserved pyridine nucleotides.

Boslett J, Helal M, Chini E, Zweier JL.

J Mol Cell Cardiol. 2018 May;118:81-94. doi: 10.1016/j.yjmcc.2018.02.015. Epub 2018 Feb 21.

46.

Caffeine affects HFD-induced hepatic steatosis by multifactorial intervention.

Helal MG, Ayoub SE, Elkashefand WF, Ibrahim TM.

Hum Exp Toxicol. 2018 Sep;37(9):983-990. doi: 10.1177/0960327117747026. Epub 2017 Dec 18.

PMID:
29249184
47.

Selective kappa opioid antagonists for treatment of addiction, are we there yet?

Helal MA, Habib ES, Chittiboyina AG.

Eur J Med Chem. 2017 Dec 1;141:632-647. doi: 10.1016/j.ejmech.2017.10.012. Epub 2017 Oct 10. Review.

PMID:
29107424
48.
49.

Effects of aqueous cinnamon extract on chemically-induced carcinoma of hamster cheek pouch mucosa.

Ezzat SK, AbuElkhair MT, Mourad MI, Helal ME, Grawish ME.

Biochem Biophys Rep. 2017 Sep 1;12:72-78. doi: 10.1016/j.bbrep.2017.08.014. eCollection 2017 Dec.

50.

Electric field and aging effects of uniaxial ferroelectrics Sr x Ba1-x Nb2O6 probed by Brillouin scattering.

Aftabuzzaman M, Helal MA, Paszkowski R, Dec J, Kleemann W, Kojima S.

Sci Rep. 2017 Sep 14;7(1):11615. doi: 10.1038/s41598-017-10985-9.

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