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Items: 10

1.

Mechanism of attenuation of leptin signaling under chronic ligand stimulation.

Knobelspies H, Zeidler J, Hekerman P, Bamberg-Lemper S, Becker W.

BMC Biochem. 2010 Jan 8;11:2. doi: 10.1186/1471-2091-11-2.

2.

The Down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4.

Sitz JH, Baumgärtel K, Hämmerle B, Papadopoulos C, Hekerman P, Tejedor FJ, Becker W, Lutz B.

Neuroscience. 2008 Dec 2;157(3):596-605. doi: 10.1016/j.neuroscience.2008.09.034. Epub 2008 Oct 1.

PMID:
18938227
3.

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.

Cunha DA, Hekerman P, Ladrière L, Bazarra-Castro A, Ortis F, Wakeham MC, Moore F, Rasschaert J, Cardozo AK, Bellomo E, Overbergh L, Mathieu C, Lupi R, Hai T, Herchuelz A, Marchetti P, Rutter GA, Eizirik DL, Cnop M.

J Cell Sci. 2008 Jul 15;121(Pt 14):2308-18. doi: 10.1242/jcs.026062. Epub 2008 Jun 17.

4.

Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1.

Maenz B, Hekerman P, Vela EM, Galceran J, Becker W.

BMC Mol Biol. 2008 Mar 26;9:30. doi: 10.1186/1471-2199-9-30.

5.

Leptin induces inflammation-related genes in RINm5F insulinoma cells.

Hekerman P, Zeidler J, Korfmacher S, Bamberg-Lemper S, Knobelspies H, Zabeau L, Tavernier J, Becker W.

BMC Mol Biol. 2007 May 23;8:41.

6.

Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis.

Cnop M, Ladriere L, Hekerman P, Ortis F, Cardozo AK, Dogusan Z, Flamez D, Boyce M, Yuan J, Eizirik DL.

J Biol Chem. 2007 Feb 9;282(6):3989-97. Epub 2006 Dec 8.

7.

BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells.

Kharroubi I, Lee CH, Hekerman P, Darville MI, Evans RM, Eizirik DL, Cnop M.

Diabetologia. 2006 Oct;49(10):2350-8. Epub 2006 Aug 5.

PMID:
16896941
8.

Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines.

Hekerman P, Zeidler J, Bamberg-Lemper S, Knobelspies H, Lavens D, Tavernier J, Joost HG, Becker W.

FEBS J. 2005 Jan;272(1):109-19.

9.

Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors.

de Graaf K, Hekerman P, Spelten O, Herrmann A, Packman LC, Büssow K, Müller-Newen G, Becker W.

J Biol Chem. 2004 Feb 6;279(6):4612-24. Epub 2003 Nov 17.

10.

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