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Items: 10

1.

A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.

Leese MP, Hejaz HA, Mahon MF, Newman SP, Purohit A, Reed MJ, Potter BV.

J Med Chem. 2005 Aug 11;48(16):5243-56.

PMID:
16078843
2.

Synthesis, in vitro and in vivo activity of benzophenone-based inhibitors of steroid sulfatase.

Hejaz HA, Woo LW, Purohit A, Reed MJ, Potter BV.

Bioorg Med Chem. 2004 May 15;12(10):2759-72.

PMID:
15110857
3.

Non-steroidal and steroidal sulfamates: new drugs for cancer therapy.

Purohit A, Woo LW, Barrow D, Hejaz HA, Nicholson RI, Potter BV, Reed MJ.

Mol Cell Endocrinol. 2001 Jan 22;171(1-2):129-35.

PMID:
11165021
4.

Differential effects of estrone and estrone-3-O-sulfamate derivatives on mitotic. Arrest, apoptosis, and microtubule assembly in human breast cancer cells.

MacCarthy-Morrogh L, Townsend PA, Purohit A, Hejaz HAM, Potter BVL, Reed MJ, Packham G.

Cancer Res. 2000 Oct 1;60(19):5441-50.

5.

Inhibition of deoxyglucose uptake in MCF-7 breast cancer cells by 2-methoxyestrone and 2-methoxyestrone-3-O-sulfamate.

Singh A, Purohit A, Hejaz HA, Potter BV, Reed MJ.

Mol Cell Endocrinol. 2000 Feb 25;160(1-2):61-6.

PMID:
10715539
6.

The effect of 2-methoxyoestrone-3-O-sulphamate on the growth of breast cancer cells and induced mammary tumours.

Purohit A, Hejaz HA, Walden L, MacCarthy-Morrogh L, Packham G, Potter BV, Reed MJ.

Int J Cancer. 2000 Feb 15;85(4):584-9.

8.

Recent advances in the development of steroid sulphatase inhibitors.

Purohit A, Hejaz HA, Woo LW, van Strien AE, Potter BV, Reed MJ.

J Steroid Biochem Mol Biol. 1999 Apr-Jun;69(1-6):227-38.

PMID:
10418996
9.

The development of A-ring modified analogues of oestrone-3-O-sulphamate as potent steroid sulphatase inhibitors with reduced oestrogenicity.

Purohit A, Vernon KA, Hummelinck AE, Woo LW, Hejaz HA, Potter BV, Reed MJ.

J Steroid Biochem Mol Biol. 1998 Mar;64(5-6):269-75.

PMID:
9618028
10.

Steroidal and nonsteroidal sulfamates as potent inhibitors of steroid sulfatase.

Woo LW, Howarth NM, Purohit A, Hejaz HA, Reed MJ, Potter BV.

J Med Chem. 1998 Mar 26;41(7):1068-83.

PMID:
9544207

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