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Items: 1 to 50 of 509

2.

Pbp1-Interacting Protein Mkt1 Regulates Virulence and Sexual Reproduction in Cryptococcus neoformans.

Son YE, Fu C, Jung WH, Oh SH, Kwak JH, Cardenas ME, Heitman J, Park HS.

Front Cell Infect Microbiol. 2019 Oct 17;9:355. doi: 10.3389/fcimb.2019.00355. eCollection 2019.

3.

Early Diverging Fungus Mucor circinelloides Lacks Centromeric Histone CENP-A and Displays a Mosaic of Point and Regional Centromeres.

Navarro-Mendoza MI, Pérez-Arques C, Panchal S, Nicolás FE, Mondo SJ, Ganguly P, Pangilinan J, Grigoriev IV, Heitman J, Sanyal K, Garre V.

Curr Biol. 2019 Oct 14. pii: S0960-9822(19)31186-8. doi: 10.1016/j.cub.2019.09.024. [Epub ahead of print]

4.

Calcium-Calmodulin-Calcineurin Signaling: A Globally Conserved Virulence Cascade in Eukaryotic Microbial Pathogens.

Park HS, Lee SC, Cardenas ME, Heitman J.

Cell Host Microbe. 2019 Oct 9;26(4):453-462. doi: 10.1016/j.chom.2019.08.004. Review.

PMID:
31600499
5.

Pathogen reduction with riboflavin and ultraviolet light induces a quasi-apoptotic state in blood leukocytes.

Tran JQ, Muench MO, Heitman JW, Jackman RP.

Transfusion. 2019 Nov;59(11):3501-3510. doi: 10.1111/trf.15516. Epub 2019 Oct 10.

PMID:
31599981
6.

She Loves Me, She Loves Me Not: On the Dualistic Asexual/Sexual Nature of Dermatophyte Fungi.

Metin B, Heitman J.

Mycopathologia. 2019 Oct 1. doi: 10.1007/s11046-019-00390-3. [Epub ahead of print]

PMID:
31578669
7.

Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.

Juvvadi PR, Fox D 3rd, Bobay BG, Hoy MJ, Gobeil SMC, Venters RA, Chang Z, Lin JJ, Averette AF, Cole DC, Barrington BC, Wheaton JD, Ciofani M, Trzoss M, Li X, Lee SC, Chen YL, Mutz M, Spicer LD, Schumacher MA, Heitman J, Steinbach WJ.

Nat Commun. 2019 Sep 19;10(1):4275. doi: 10.1038/s41467-019-12199-1.

8.

The Evolution of Sexual Reproduction and the Mating-Type Locus: Links to Pathogenesis of Cryptococcus Human Pathogenic Fungi.

Sun S, Coelho MA, David-Palma M, Priest S, Heitman J.

Annu Rev Genet. 2019 Sep 19. doi: 10.1146/annurev-genet-120116-024755. [Epub ahead of print]

PMID:
31537103
9.

Unisexual reproduction promotes competition for mating partners in the global human fungal pathogen Cryptococcus deneoformans.

Fu C, Thielhelm TP, Heitman J.

PLoS Genet. 2019 Sep 19;15(9):e1008394. doi: 10.1371/journal.pgen.1008394. eCollection 2019 Sep.

10.

Convergent evolution of linked mating-type loci in basidiomycete fungi.

Sun S, Coelho MA, Heitman J, Nowrousian M.

PLoS Genet. 2019 Sep 6;15(9):e1008365. doi: 10.1371/journal.pgen.1008365. eCollection 2019 Sep.

11.

E Pluribus Unum: The Fungal Kingdom as a Rosetta Stone for Biology and Medicine.

Heitman J.

Genetics. 2019 Sep;213(1):1-7. doi: 10.1534/genetics.119.302537.

PMID:
31488591
12.

Genetic and genomic evolution of sexual reproduction: echoes from LECA to the fungal kingdom.

Fu C, Coelho MA, David-Palma M, Priest SJ, Heitman J.

Curr Opin Genet Dev. 2019 Aug 29;58-59:70-75. doi: 10.1016/j.gde.2019.07.008. [Epub ahead of print] Review.

PMID:
31473482
13.

Mating-System Evolution: All Roads Lead to Selfing.

Sun S, Lin X, Coelho MA, Heitman J.

Curr Biol. 2019 Aug 5;29(15):R743-R746. doi: 10.1016/j.cub.2019.06.073.

PMID:
31386850
14.

Epigenetic mechanisms of drug resistance in fungi.

Chang Z, Yadav V, Lee SC, Heitman J.

Fungal Genet Biol. 2019 Nov;132:103253. doi: 10.1016/j.fgb.2019.103253. Epub 2019 Jul 17. Review.

PMID:
31325489
15.

Potential of Membranes Surrounding the Fetus as Immunoprotective Cell-Carriers for Allogeneic Transplantations.

Togarrati PP, Dinglasan N, Yee E, Heitman JW, Jackman RP, Geisberg M, Norris PJ, Bárcena A, Muench MO.

Transplant Direct. 2019 May 29;5(6):e460. doi: 10.1097/TXD.0000000000000901. eCollection 2019 Jun.

16.

Advancing Functional Genetics Through Agrobacterium-Mediated Insertional Mutagenesis and CRISPR/Cas9 in the Commensal and Pathogenic Yeast Malassezia.

Ianiri G, Dagotto G, Sun S, Heitman J.

Genetics. 2019 Aug;212(4):1163-1179. doi: 10.1534/genetics.119.302329. Epub 2019 Jun 26.

PMID:
31243056
17.

Genetic and Genomic Analyses Reveal Boundaries between Species Closely Related to Cryptococcus Pathogens.

Passer AR, Coelho MA, Billmyre RB, Nowrousian M, Mittelbach M, Yurkov AM, Averette AF, Cuomo CA, Sun S, Heitman J.

MBio. 2019 Jun 11;10(3). pii: e00764-19. doi: 10.1128/mBio.00764-19.

18.

Gastrointestinal microbiota alteration induced by Mucor circinelloides in a murine model.

Mueller KD, Zhang H, Serrano CR, Billmyre RB, Huh EY, Wiemann P, Keller NP, Wang Y, Heitman J, Lee SC.

J Microbiol. 2019 Jun;57(6):509-520. doi: 10.1007/s12275-019-8682-x. Epub 2019 May 27.

19.

Nutrient and Stress Sensing in Pathogenic Yeasts.

Rutherford JC, Bahn YS, van den Berg B, Heitman J, Xue C.

Front Microbiol. 2019 Mar 8;10:442. doi: 10.3389/fmicb.2019.00442. eCollection 2019. Review.

20.

Influence of blood storage age on immune and coagulation parameters in critically ill transfused patients.

Norris PJ, Schechtman K, Inglis HC, Adelman A, Heitman JW, Vilardi R, Shah A, Roubinian NH, Danesh A, Guiltinan AM, Keating SM, Lacroix J, Cohen MJ, Spinella PC.

Transfusion. 2019 Apr;59(4):1223-1232. doi: 10.1111/trf.15250. Epub 2019 Mar 18.

PMID:
30882927
21.

Fungi in the Marine Environment: Open Questions and Unsolved Problems.

Amend A, Burgaud G, Cunliffe M, Edgcomb VP, Ettinger CL, Gutiérrez MH, Heitman J, Hom EFY, Ianiri G, Jones AC, Kagami M, Picard KT, Quandt CA, Raghukumar S, Riquelme M, Stajich J, Vargas-Muñiz J, Walker AK, Yarden O, Gladfelter AS.

MBio. 2019 Mar 5;10(2). pii: e01189-18. doi: 10.1128/mBio.01189-18. Review.

22.

Effects of blood storage age on immune, coagulation, and nitric oxide parameters in transfused patients undergoing cardiac surgery.

Spinella PC, Sniecinski RM, Trachtenberg F, Inglis HC, Ranganathan G, Heitman JW, Szlam F, Danesh A, Stone M, Keating SM, Levy JH, Assmann SF, Steiner ME, Doctor A, Norris PJ.

Transfusion. 2019 Apr;59(4):1209-1222. doi: 10.1111/trf.15228. Epub 2019 Mar 5.

PMID:
30835880
23.

Cryptococcus deuterogattii VGIIa Infection Associated with Travel to the Pacific Northwest Outbreak Region in an Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibody-Positive Patient in the United States.

Applen Clancey S, Ciccone EJ, Coelho MA, Davis J, Ding L, Betancourt R, Glaubiger S, Lee Y, Holland SM, Gilligan P, Sung J, Heitman J.

MBio. 2019 Feb 12;10(1). pii: e02733-18. doi: 10.1128/mBio.02733-18.

24.

Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides.

Chang Z, Billmyre RB, Lee SC, Heitman J.

PLoS Genet. 2019 Feb 11;15(2):e1007957. doi: 10.1371/journal.pgen.1007957. eCollection 2019 Feb.

25.

Allogeneic major histocompatibility complex antigens are necessary and sufficient for partial tolerance induced by transfusion of pathogen reduced platelets in mice.

Tran JQ, Muench MO, Heitman JW, Jackman RP.

Vox Sang. 2019 Apr;114(3):207-215. doi: 10.1111/vox.12756. Epub 2019 Feb 7.

PMID:
30734299
26.

Mucor circinelloides Thrives inside the Phagosome through an Atf-Mediated Germination Pathway.

Pérez-Arques C, Navarro-Mendoza MI, Murcia L, Lax C, Martínez-García P, Heitman J, Nicolás FE, Garre V.

MBio. 2019 Feb 5;10(1). pii: e02765-18. doi: 10.1128/mBio.02765-18.

27.

Cryptococcus neoformans Mating and Genetic Crosses.

Sun S, Priest SJ, Heitman J.

Curr Protoc Microbiol. 2019 Jun;53(1):e75. doi: 10.1002/cpmc.75. Epub 2019 Jan 20.

PMID:
30661293
28.

Mating type (MAT) locus and possible sexuality of the opportunistic pathogen Exophiala dermatitidis.

Metin B, Döğen A, Yıldırım E, de Hoog GS, Heitman J, Ilkit M.

Fungal Genet Biol. 2019 Mar;124:29-38. doi: 10.1016/j.fgb.2018.12.011. Epub 2019 Jan 3.

PMID:
30611834
29.

In Vitro and In Vivo Assessment of FK506 Analogs as Novel Antifungal Drug Candidates.

Lee Y, Lee KT, Lee SJ, Beom JY, Hwangbo A, Jung JA, Song MC, Yoo YJ, Kang SH, Averette AF, Heitman J, Yoon YJ, Cheong E, Bahn YS.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01627-18. doi: 10.1128/AAC.01627-18. Print 2018 Nov.

30.

An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease.

Wang L, Pittman KJ, Barker JR, Salinas RE, Stanaway IB, Williams GD, Carroll RJ, Balmat T, Ingham A, Gopalakrishnan AM, Gibbs KD, Antonia AL; eMERGE Network, Heitman J, Lee SC, Jarvik GP, Denny JC, Horner SM, DeLong MR, Valdivia RH, Crosslin DR, Ko DC.

Cell Host Microbe. 2018 Aug 8;24(2):308-323.e6. doi: 10.1016/j.chom.2018.07.007.

31.

Granulocyte-Derived Extracellular Vesicles Activate Monocytes and Are Associated With Mortality in Intensive Care Unit Patients.

Danesh A, Inglis HC, Abdel-Mohsen M, Deng X, Adelman A, Schechtman KB, Heitman JW, Vilardi R, Shah A, Keating SM, Cohen MJ, Jacobs ES, Pillai SK, Lacroix J, Spinella PC, Norris PJ.

Front Immunol. 2018 May 8;9:956. doi: 10.3389/fimmu.2018.00956. eCollection 2018.

32.

Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex.

Jung KW, Lee KT, Averette AF, Hoy MJ, Everitt J, Heitman J, Bahn YS.

Sci Rep. 2018 May 25;8(1):8132. doi: 10.1038/s41598-018-26405-5.

33.

Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing.

Garcia-Hermoso D, Criscuolo A, Lee SC, Legrand M, Chaouat M, Denis B, Lafaurie M, Rouveau M, Soler C, Schaal JV, Mimoun M, Mebazaa A, Heitman J, Dromer F, Brisse S, Bretagne S, Alanio A.

MBio. 2018 Apr 24;9(2). pii: e00573-18. doi: 10.1128/mBio.00573-18.

34.

The Skin Commensal Yeast Malassezia globosa Thwarts Bacterial Biofilms to Benefit the Host.

Ianiri G, Heitman J, Scheynius A.

J Invest Dermatol. 2018 May;138(5):1026-1029. doi: 10.1016/j.jid.2018.01.008.

PMID:
29681390
35.

Phylogenetic and Phylogenomic Definition of Rhizopus Species.

Gryganskyi AP, Golan J, Dolatabadi S, Mondo S, Robb S, Idnurm A, Muszewska A, Steczkiewicz K, Masonjones S, Liao HL, Gajdeczka MT, Anike F, Vuek A, Anishchenko IM, Voigt K, de Hoog GS, Smith ME, Heitman J, Vilgalys R, Stajich JE.

G3 (Bethesda). 2018 May 31;8(6):2007-2018. doi: 10.1534/g3.118.200235. Erratum in: G3 (Bethesda). 2019 Aug 8;9(8):2789.

36.

A High-Resolution Map of Meiotic Recombination in Cryptococcus deneoformans Demonstrates Decreased Recombination in Unisexual Reproduction.

Roth C, Sun S, Billmyre RB, Heitman J, Magwene PM.

Genetics. 2018 Jun;209(2):567-578. doi: 10.1534/genetics.118.300996. Epub 2018 Apr 6.

37.

Pearls collections: What we can learn about infectious disease and cancer.

Knoll LJ, Hogan DA, Leong JM, Heitman J, Condit RC.

PLoS Pathog. 2018 Mar 29;14(3):e1006915. doi: 10.1371/journal.ppat.1006915. eCollection 2018 Mar. No abstract available.

38.

RNAi is a critical determinant of centromere evolution in closely related fungi.

Yadav V, Sun S, Billmyre RB, Thimmappa BC, Shea T, Lintner R, Bakkeren G, Cuomo CA, Heitman J, Sanyal K.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3108-3113. doi: 10.1073/pnas.1713725115. Epub 2018 Mar 5.

39.

Whole-Genome Analysis Illustrates Global Clonal Population Structure of the Ubiquitous Dermatophyte Pathogen Trichophyton rubrum.

Persinoti GF, Martinez DA, Li W, Döğen A, Billmyre RB, Averette A, Goldberg JM, Shea T, Young S, Zeng Q, Oliver BG, Barton R, Metin B, Hilmioğlu-Polat S, Ilkit M, Gräser Y, Martinez-Rossi NM, White TC, Heitman J, Cuomo CA.

Genetics. 2018 Apr;208(4):1657-1669. doi: 10.1534/genetics.117.300573. Epub 2018 Feb 21.

40.

Incapacitated Surrogates: A New and Increasing Dilemma in Hospital Care.

Smith KL, Fedel P, Heitman J.

J Clin Ethics. 2017 Winter;28(4):279-289.

PMID:
29257763
41.

Had1 Is Required for Cell Wall Integrity and Fungal Virulence in Cryptococcus neoformans.

Jung WH, Son YE, Oh SH, Fu C, Kim HS, Kwak JH, Cardenas ME, Heitman J, Park HS.

G3 (Bethesda). 2018 Feb 2;8(2):643-652. doi: 10.1534/g3.117.300444.

42.

Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans.

Fu C, Donadio N, Cardenas ME, Heitman J.

Genetics. 2018 Feb;208(2):639-653. doi: 10.1534/genetics.117.300422. Epub 2017 Dec 12.

43.

Erratum for Ianiri et al., "FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in Malassezia".

Ianiri G, Applen Clancey S, Lee SC, Heitman J.

MBio. 2017 Dec 5;8(6). pii: e02055-17. doi: 10.1128/mBio.02055-17. No abstract available.

44.

PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex.

Fu C, Heitman J.

PLoS Genet. 2017 Nov 27;13(11):e1007113. doi: 10.1371/journal.pgen.1007113. eCollection 2017 Nov.

45.

FKBP12-Dependent Inhibition of Calcineurin Mediates Immunosuppressive Antifungal Drug Action in Malassezia.

Ianiri G, Applen Clancey S, Lee SC, Heitman J.

MBio. 2017 Oct 24;8(5). pii: e01752-17. doi: 10.1128/mBio.01752-17. Erratum in: MBio. 2017 Dec 5;8(6):.

46.

Natural mismatch repair mutations mediate phenotypic diversity and drug resistance in Cryptococcus deuterogattii.

Billmyre RB, Clancey SA, Heitman J.

Elife. 2017 Sep 26;6. pii: e28802. doi: 10.7554/eLife.28802.

47.

Genetic and epigenetic engines of diversity in pathogenic microbes.

Billmyre RB, Heitman J.

PLoS Pathog. 2017 Sep 14;13(9):e1006468. doi: 10.1371/journal.ppat.1006468. eCollection 2017 Sep. Review. No abstract available.

48.

The effect of HIV infection and HCV viremia on inflammatory mediators and hepatic injury-The Women's Interagency HIV Study.

Keating SM, Dodge JL, Norris PJ, Heitman J, Gange SJ, French AL, Glesby MJ, Edlin BR, Latham PS, Villacres MC, Greenblatt RM, Peters MG; Women’s Interagency HIV Study.

PLoS One. 2017 Sep 13;12(9):e0181004. doi: 10.1371/journal.pone.0181004. eCollection 2017.

49.

Eukaryotic Sexual Reproduction Evoked "with a Little Help from My Friends".

Umen J, Goodenough U, Heitman J.

Cell. 2017 Sep 7;170(6):1059-1061. doi: 10.1016/j.cell.2017.08.038.

50.

A multi-year study of tillage and amendment effects on compacted soils.

Mohammadshirazi F, McLaughlin RA, Heitman JL, Brown VK.

J Environ Manage. 2017 Dec 1;203(Pt 1):533-541. doi: 10.1016/j.jenvman.2017.07.031. Epub 2017 Aug 30.

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