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Items: 11

1.

CIC protein instability contributes to tumorigenesis in glioblastoma.

Bunda S, Heir P, Metcalf J, Li ASC, Agnihotri S, Pusch S, Yasin M, Li M, Burrell K, Mansouri S, Singh O, Wilson M, Alamsahebpour A, Nejad R, Choi B, Kim D, von Deimling A, Zadeh G, Aldape K.

Nat Commun. 2019 Feb 8;10(1):661. doi: 10.1038/s41467-018-08087-9.

2.

Hydroxylation-Dependent Interaction of Substrates to the Von Hippel-Lindau Tumor Suppressor Protein (VHL).

Heir P, Ohh M.

Methods Mol Biol. 2016;1458:87-94. doi: 10.1007/978-1-4939-3801-8_7.

PMID:
27581016
3.

Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling.

Heir P, Srikumar T, Bikopoulos G, Bunda S, Poon BP, Lee JE, Raught B, Ohh M.

J Biol Chem. 2016 Apr 1;291(14):7357-72. doi: 10.1074/jbc.M115.694562. Epub 2016 Feb 4.

4.

Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis.

Bunda S, Burrell K, Heir P, Zeng L, Alamsahebpour A, Kano Y, Raught B, Zhang ZY, Zadeh G, Ohh M.

Nat Commun. 2015 Nov 30;6:8859. doi: 10.1038/ncomms9859.

5.

Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation.

Bunda S, Heir P, Srikumar T, Cook JD, Burrell K, Kano Y, Lee JE, Zadeh G, Raught B, Ohh M.

Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3785-94. doi: 10.1073/pnas.1406559111. Epub 2014 Aug 25.

6.

Juvenile myelomonocytic leukaemia-associated mutation in Cbl promotes resistance to apoptosis via the Lyn-PI3K/AKT pathway.

Bunda S, Qin K, Kommaraju K, Heir P, Ohh M.

Oncogene. 2015 Feb 5;34(6):789-97. doi: 10.1038/onc.2013.596. Epub 2014 Jan 27.

PMID:
24469048
7.

SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor.

Bunda S, Kommaraju K, Heir P, Ohh M.

PLoS One. 2013 Sep 26;8(9):e76370. doi: 10.1371/journal.pone.0076370. eCollection 2013.

8.

DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.

Heir P, Sufan RI, Greer SN, Poon BP, Lee JE, Ohh M.

Mol Cell Biol. 2013 Apr;33(8):1621-31. doi: 10.1128/MCB.01342-12. Epub 2013 Feb 11.

9.

Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1.

Wang Y, Roche O, Xu C, Moriyama EH, Heir P, Chung J, Roos FC, Chen Y, Finak G, Milosevic M, Wilson BC, Teh BT, Park M, Irwin MS, Ohh M.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4892-7. doi: 10.1073/pnas.1112129109. Epub 2012 Mar 12.

10.

Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.

Russell RC, Sufan RI, Zhou B, Heir P, Bunda S, Sybingco SS, Greer SN, Roche O, Heathcote SA, Chow VW, Boba LM, Richmond TD, Hickey MM, Barber DL, Cheresh DA, Simon MC, Irwin MS, Kim WY, Ohh M.

Nat Med. 2011 Jun 19;17(7):845-53. doi: 10.1038/nm.2370.

11.

Deregulation of E2-EPF ubiquitin carrier protein in papillary renal cell carcinoma.

Roos FC, Evans AJ, Brenner W, Wondergem B, Klomp J, Heir P, Roche O, Thomas C, Schimmel H, Furge KA, Teh BT, Thüroff JW, Hampel C, Ohh M.

Am J Pathol. 2011 Feb;178(2):853-60. doi: 10.1016/j.ajpath.2010.10.033.

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