Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 273


Examination of Bacterial Artificial Chromosome (BAC) DNA Quality and Quantity by Pulsed-Field Gel Electrophoresis.

Heintz N, Gong S.

Cold Spring Harb Protoc. 2019 Nov 1;2019(11):pdb.prot098020. doi: 10.1101/pdb.prot098020.


Large-Scale Preparation and Linearization of Bacterial Artificial Chromosome (BAC) DNA.

Heintz N, Gong S.

Cold Spring Harb Protoc. 2019 Nov 1;2019(11):pdb.prot098012. doi: 10.1101/pdb.prot098012.


Small-Scale Isolation of Bacterial Artificial Chromosome (BAC) DNA and Verification by Polymerase Chain Reaction (PCR).

Heintz N, Gong S.

Cold Spring Harb Protoc. 2019 Nov 1;2019(11):pdb.prot098004. doi: 10.1101/pdb.prot098004.


Peroxiredoxins and Beyond; Redox Systems Regulating Lung Physiology and Disease.

Elko EA, Cunniff B, Seward DJ, Chia SB, Aboushousha R, van de Wetering C, van der Velden J, Manuel A, Shukla A, Heintz NH, Anathy V, van der Vliet A, Janssen-Heininger YMW.

Antioxid Redox Signal. 2019 Nov 10;31(14):1070-1091. doi: 10.1089/ars.2019.7752. Epub 2019 Apr 5.


Species and cell-type properties of classically defined human and rodent neurons and glia.

Xu X, Stoyanova EI, Lemiesz AE, Xing J, Mash DC, Heintz N.

Elife. 2018 Oct 15;7. pii: e37551. doi: 10.7554/eLife.37551.


Molecular and Functional Sex Differences of Noradrenergic Neurons in the Mouse Locus Coeruleus.

Mulvey B, Bhatti DL, Gyawali S, Lake AM, Kriaucionis S, Ford CP, Bruchas MR, Heintz N, Dougherty JD.

Cell Rep. 2018 May 22;23(8):2225-2235. doi: 10.1016/j.celrep.2018.04.054.


Cell-Type-Specific Contributions of Medial Prefrontal Neurons to Flexible Behaviors.

Nakayama H, Ibañez-Tallon I, Heintz N.

J Neurosci. 2018 May 9;38(19):4490-4504. doi: 10.1523/JNEUROSCI.3537-17.2018. Epub 2018 Apr 12.


Retrograde inhibition by a specific subset of interpeduncular α5 nicotinic neurons regulates nicotine preference.

Ables JL, Görlich A, Antolin-Fontes B, Wang C, Lipford SM, Riad MH, Ren J, Hu F, Luo M, Kenny PJ, Heintz N, Ibañez-Tallon I.

Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):13012-13017. doi: 10.1073/pnas.1717506114. Epub 2017 Nov 20.


5-hydroxymethylcytosine accumulation in postmitotic neurons results in functional demethylation of expressed genes.

Mellén M, Ayata P, Heintz N.

Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7812-E7821. doi: 10.1073/pnas.1708044114. Epub 2017 Aug 28.


Rapid Molecular Profiling of Defined Cell Types Using Viral TRAP.

Nectow AR, Moya MV, Ekstrand MI, Mousa A, McGuire KL, Sferrazza CE, Field BC, Rabinowitz GS, Sawicka K, Liang Y, Friedman JM, Heintz N, Schmidt EF.

Cell Rep. 2017 Apr 18;19(3):655-667. doi: 10.1016/j.celrep.2017.03.048.


The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn.

Abraira VE, Kuehn ED, Chirila AM, Springel MW, Toliver AA, Zimmerman AL, Orefice LL, Boyle KA, Bai L, Song BJ, Bashista KA, O'Neill TG, Zhuo J, Tsan C, Hoynoski J, Rutlin M, Kus L, Niederkofler V, Watanabe M, Dymecki SM, Nelson SB, Heintz N, Hughes DI, Ginty DD.

Cell. 2017 Jan 12;168(1-2):295-310.e19. doi: 10.1016/j.cell.2016.12.010. Epub 2016 Dec 29.


A Cortical Circuit for Sexually Dimorphic Oxytocin-Dependent Anxiety Behaviors.

Li K, Nakajima M, Ibañez-Tallon I, Heintz N.

Cell. 2016 Sep 22;167(1):60-72.e11. doi: 10.1016/j.cell.2016.08.067. Epub 2016 Sep 15.


AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion.

Cunniff B, McKenzie AJ, Heintz NH, Howe AK.

Mol Biol Cell. 2016 Sep 1;27(17):2662-74. doi: 10.1091/mbc.E16-05-0286. Epub 2016 Jul 6.


Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons.

Miyoshi G, Young A, Petros T, Karayannis T, McKenzie Chang M, Lavado A, Iwano T, Nakajima M, Taniguchi H, Huang ZJ, Heintz N, Oliver G, Matsuzaki F, Machold RP, Fishell G.

J Neurosci. 2015 Sep 16;35(37):12869-89. doi: 10.1523/JNEUROSCI.1164-15.2015.


Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors.

Shrestha P, Mousa A, Heintz N.

Elife. 2015 Sep 15;4. doi: 10.7554/eLife.08752.


Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma.

Cunniff B, Newick K, Nelson KJ, Wozniak AN, Beuschel S, Leavitt B, Bhave A, Butnor K, Koenig A, Chouchani ET, James AM, Haynes AC, Lowther WT, Murphy MP, Shukla A, Heintz NH.

PLoS One. 2015 May 26;10(5):e0127310. doi: 10.1371/journal.pone.0127310. eCollection 2015.


Peroxiredoxin 3 levels regulate a mitochondrial redox setpoint in malignant mesothelioma cells.

Cunniff B, Wozniak AN, Sweeney P, DeCosta K, Heintz NH.

Redox Biol. 2014;3:79-87. doi: 10.1016/j.redox.2014.11.003. Epub 2014 Nov 18.


Nitric oxide regulates synaptic transmission between spiny projection neurons.

Sagi Y, Heiman M, Peterson JD, Musatov S, Scarduzio M, Logan SM, Kaplitt MG, Surmeier DJ, Heintz N, Greengard P.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17636-41. doi: 10.1073/pnas.1420162111. Epub 2014 Nov 20. Erratum in: Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1811.


Oxytocin modulates female sociosexual behavior through a specific class of prefrontal cortical interneurons.

Nakajima M, Görlich A, Heintz N.

Cell. 2014 Oct 9;159(2):295-305. doi: 10.1016/j.cell.2014.09.020.


Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.

McKnight NC, Zhong Y, Wold MS, Gong S, Phillips GR, Dou Z, Zhao Y, Heintz N, Zong WX, Yue Z.

PLoS Genet. 2014 Oct 2;10(10):e1004626. doi: 10.1371/journal.pgen.1004626. eCollection 2014 Oct.


Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation.

Thompson JK, Westbom CM, MacPherson MB, Mossman BT, Heintz NH, Spiess P, Shukla A.

Part Fibre Toxicol. 2014 May 20;11:24. doi: 10.1186/1743-8977-11-24.


Cell type-specific mRNA purification by translating ribosome affinity purification (TRAP).

Heiman M, Kulicke R, Fenster RJ, Greengard P, Heintz N.

Nat Protoc. 2014;9(6):1282-91. doi: 10.1038/nprot.2014.085. Epub 2014 May 8.


Resolution of oxidative stress by thioredoxin reductase: Cysteine versus selenocysteine.

Cunniff B, Snider GW, Fredette N, Stumpff J, Hondal RJ, Heintz NH.

Redox Biol. 2014 Feb 19;2:475-84. doi: 10.1016/j.redox.2014.01.021. eCollection 2014.


Control of stress-induced persistent anxiety by an extra-amygdala septohypothalamic circuit.

Anthony TE, Dee N, Bernard A, Lerchner W, Heintz N, Anderson DJ.

Cell. 2014 Jan 30;156(3):522-36. doi: 10.1016/j.cell.2013.12.040.


GENSAT BAC cre-recombinase driver lines to study the functional organization of cerebral cortical and basal ganglia circuits.

Gerfen CR, Paletzki R, Heintz N.

Neuron. 2013 Dec 18;80(6):1368-83. doi: 10.1016/j.neuron.2013.10.016.


The neuron identity problem: form meets function.

Fishell G, Heintz N.

Neuron. 2013 Oct 30;80(3):602-12. doi: 10.1016/j.neuron.2013.10.035.


A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates.

Cunniff B, Snider GW, Fredette N, Hondal RJ, Heintz NH.

Anal Biochem. 2013 Dec 1;443(1):34-40. doi: 10.1016/j.ab.2013.08.013. Epub 2013 Aug 21.


Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development.

Rommel PC, Bosque D, Gitlin AD, Croft GF, Heintz N, Casellas R, Nussenzweig MC, Kriaucionis S, Robbiani DF.

PLoS One. 2013 Jul 8;8(7):e69208. doi: 10.1371/journal.pone.0069208. Print 2013.


The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons.

Lanoue V, Usardi A, Sigoillot SM, Talleur M, Iyer K, Mariani J, Isope P, Vodjdani G, Heintz N, Selimi F.

Mol Psychiatry. 2013 Aug;18(8):943-50. doi: 10.1038/mp.2013.46. Epub 2013 Apr 30.


BAC transgenic mice and the GENSAT database of engineered mouse strains.

Schmidt EF, Kus L, Gong S, Heintz N.

Cold Spring Harb Protoc. 2013 Mar 1;2013(3). pii: pdb.top073692. doi: 10.1101/pdb.top073692.


Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation.

Dalal J, Roh JH, Maloney SE, Akuffo A, Shah S, Yuan H, Wamsley B, Jones WB, de Guzman Strong C, Gray PA, Holtzman DM, Heintz N, Dougherty JD.

Genes Dev. 2013 Mar 1;27(5):565-78. doi: 10.1101/gad.207654.112. Epub 2013 Feb 21.


The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors.

Dougherty JD, Maloney SE, Wozniak DF, Rieger MA, Sonnenblick L, Coppola G, Mahieu NG, Zhang J, Cai J, Patti GJ, Abrahams BS, Geschwind DH, Heintz N.

J Neurosci. 2013 Feb 13;33(7):2732-53. doi: 10.1523/JNEUROSCI.4762-12.2013.


New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas.

Mossman BT, Shukla A, Heintz NH, Verschraegen CF, Thomas A, Hassan R.

Am J Pathol. 2013 Apr;182(4):1065-77. doi: 10.1016/j.ajpath.2012.12.028. Epub 2013 Feb 8. Review.


MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.

Mellén M, Ayata P, Dewell S, Kriaucionis S, Heintz N.

Cell. 2012 Dec 21;151(7):1417-30. doi: 10.1016/j.cell.2012.11.022.


Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells.

Cunniff B, Benson K, Stumpff J, Newick K, Held P, Taatjes D, Joseph J, Kalyanaraman B, Heintz NH.

J Cell Physiol. 2013 Apr;228(4):835-45. doi: 10.1002/jcp.24232.


IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.

Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, Oakes SA, Papa FR.

Cell Metab. 2012 Aug 8;16(2):250-64. doi: 10.1016/j.cmet.2012.07.007.


Mouse transgenesis in a single locus with independent regulation for multiple fluorophores.

Dougherty JD, Zhang J, Feng H, Gong S, Heintz N.

PLoS One. 2012;7(7):e40511. doi: 10.1371/journal.pone.0040511. Epub 2012 Jul 12.


The biochemical anatomy of cortical inhibitory synapses.

Heller EA, Zhang W, Selimi F, Earnheart JC, Ślimak MA, Santos-Torres J, Ibañez-Tallon I, Aoki C, Chait BT, Heintz N.

PLoS One. 2012;7(6):e39572. doi: 10.1371/journal.pone.0039572. Epub 2012 Jun 29.


Strain-specific regulation of striatal phenotype in Drd2-eGFP BAC transgenic mice.

Chan CS, Peterson JD, Gertler TS, Glajch KE, Quintana RE, Cui Q, Sebel LE, Plotkin JL, Shen W, Heiman M, Heintz N, Greengard P, Surmeier DJ.

J Neurosci. 2012 Jul 4;32(27):9124-32. doi: 10.1523/JNEUROSCI.0229-12.2012.


Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells.

Newick K, Cunniff B, Preston K, Held P, Arbiser J, Pass H, Mossman B, Shukla A, Heintz N.

PLoS One. 2012;7(6):e39404. doi: 10.1371/journal.pone.0039404. Epub 2012 Jun 25.


Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis.

Anathy V, Roberson E, Cunniff B, Nolin JD, Hoffman S, Spiess P, Guala AS, Lahue KG, Goldman D, Flemer S, van der Vliet A, Heintz NH, Budd RC, Tew KD, Janssen-Heininger YM.

Mol Cell Biol. 2012 Sep;32(17):3464-78. doi: 10.1128/MCB.00125-12. Epub 2012 Jul 2.


Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior.

Warner-Schmidt JL, Schmidt EF, Marshall JJ, Rubin AJ, Arango-Lievano M, Kaplitt MG, Ibañez-Tallon I, Heintz N, Greengard P.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11360-5. doi: 10.1073/pnas.1209293109. Epub 2012 Jun 25.


Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord.

Tien AC, Tsai HH, Molofsky AV, McMahon M, Foo LC, Kaul A, Dougherty JD, Heintz N, Gutmann DH, Barres BA, Rowitch DH.

Development. 2012 Jul;139(14):2477-87. doi: 10.1242/dev.077214. Epub 2012 Jun 6.


Identification of the cortical neurons that mediate antidepressant responses.

Schmidt EF, Warner-Schmidt JL, Otopalik BG, Pickett SB, Greengard P, Heintz N.

Cell. 2012 May 25;149(5):1152-63. doi: 10.1016/j.cell.2012.03.038.


Reprogramming axonal behavior by axon-specific viral transduction.

Walker BA, Hengst U, Kim HJ, Jeon NL, Schmidt EF, Heintz N, Milner TA, Jaffrey SR.

Gene Ther. 2012 Sep;19(9):947-55. doi: 10.1038/gt.2011.217. Epub 2012 Jan 26.


The functional organization of cutaneous low-threshold mechanosensory neurons.

Li L, Rutlin M, Abraira VE, Cassidy C, Kus L, Gong S, Jankowski MP, Luo W, Heintz N, Koerber HR, Woodbury CJ, Ginty DD.

Cell. 2011 Dec 23;147(7):1615-27. doi: 10.1016/j.cell.2011.11.027.


Activation of hypoxia-inducible factor-1 protects airway epithelium against oxidant-induced barrier dysfunction.

Olson N, Hristova M, Heintz NH, Lounsbury KM, van der Vliet A.

Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L993-L1002. doi: 10.1152/ajplung.00250.2011. Epub 2011 Sep 16.


Acute cocaine induces fast activation of D1 receptor and progressive deactivation of D2 receptor striatal neurons: in vivo optical microprobe [Ca2+]i imaging.

Luo Z, Volkow ND, Heintz N, Pan Y, Du C.

J Neurosci. 2011 Sep 14;31(37):13180-90. doi: 10.1523/JNEUROSCI.2369-11.2011.


ERK2 is essential for the growth of human epithelioid malignant mesotheliomas.

Shukla A, Hillegass JM, MacPherson MB, Beuschel SL, Vacek PM, Butnor KJ, Pass HI, Carbone M, Testa JR, Heintz NH, Mossman BT.

Int J Cancer. 2011 Sep 1;129(5):1075-86. doi: 10.1002/ijc.25763. Epub 2011 Jan 6.


Lynx1, a cholinergic brake, limits plasticity in adult visual cortex.

Morishita H, Miwa JM, Heintz N, Hensch TK.

Science. 2010 Nov 26;330(6008):1238-40. doi: 10.1126/science.1195320. Epub 2010 Nov 11.

Supplemental Content

Loading ...
Support Center