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Items: 1 to 50 of 85

1.

CRUP: a comprehensive framework to predict condition-specific regulatory units.

Ramisch A, Heinrich V, Glaser LV, Fuchs A, Yang X, Benner P, Schöpflin R, Li N, Kinkley S, Römer-Hillmann A, Longinotto J, Heyne S, Czepukojc B, Kessler SM, Kiemer AK, Cadenas C, Arrigoni L, Gasparoni N, Manke T, Pap T, Pospisilik JA, Hengstler J, Walter J, Meijsing SH, Chung HR, Vingron M.

Genome Biol. 2019 Nov 8;20(1):227. doi: 10.1186/s13059-019-1860-7.

2.

Technical emptiability of dairy product packaging and its environmental implications in Austria.

Wohner B, Schwarzinger N, Gürlich U, Heinrich V, Tacker M.

PeerJ. 2019 Sep 10;7:e7578. doi: 10.7717/peerj.7578. eCollection 2019.

3.

Maternal Antibodies Provide Bank Voles with Strain-Specific Protection against Infection by the Lyme Disease Pathogen.

Gomez-Chamorro A, Heinrich V, Sarr A, Roethlisberger O, Genné D, Bregnard C, Jacquet M, Voordouw MJ.

Appl Environ Microbiol. 2019 Nov 14;85(23). pii: e01887-19. doi: 10.1128/AEM.01887-19. Print 2019 Dec 1.

PMID:
31540991
4.

Force-induced recruitment of cten along keratin network in epithelial cells.

Cheah JS, Jacobs KA, Heinrich V, Lo SH, Yamada S.

Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19799-19801. doi: 10.1073/pnas.1911865116. Epub 2019 Sep 16.

5.

Preformed chromatin topology assists transcriptional robustness of Shh during limb development.

Paliou C, Guckelberger P, Schöpflin R, Heinrich V, Esposito A, Chiariello AM, Bianco S, Annunziatella C, Helmuth J, Haas S, Jerković I, Brieske N, Wittler L, Timmermann B, Nicodemi M, Vingron M, Mundlos S, Andrey G.

Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12390-12399. doi: 10.1073/pnas.1900672116. Epub 2019 May 30.

PMID:
31147463
6.

Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations.

Kraft K, Magg A, Heinrich V, Riemenschneider C, Schöpflin R, Markowski J, Ibrahim DM, Acuna-Hidalgo R, Despang A, Andrey G, Wittler L, Timmermann B, Vingron M, Mundlos S.

Nat Cell Biol. 2019 Mar;21(3):305-310. doi: 10.1038/s41556-019-0273-x. Epub 2019 Feb 11.

PMID:
30742094
7.

Hyperthermic chest wall re-irradiation in recurrent breast cancer: a prospective observational study.

De-Colle C, Weidner N, Heinrich V, Brucker S, Hahn M, MacMillan K, Lamprecht U, Gaupp S, Voigt O, Zips D.

Strahlenther Onkol. 2019 Apr;195(4):318-326. doi: 10.1007/s00066-018-1414-z. Epub 2019 Jan 3.

PMID:
30607453
8.

Immunotherapy plus surgery/radiosurgery is associated with favorable survival in patients with melanoma brain metastasis.

Amaral T, Tampouri I, Eigentler T, Keim U, Klumpp B, Heinrich V, Zips D, Paulsen F, Gepfner-Tuma I, Skardelly M, Tatagiba M, Tabatabai G, Garbe C, Forschner A.

Immunotherapy. 2019 Mar;11(4):297-309. doi: 10.2217/imt-2018-0149. Epub 2019 Jan 4.

PMID:
30606066
9.

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis.

Kragesteen BK, Spielmann M, Paliou C, Heinrich V, Schöpflin R, Esposito A, Annunziatella C, Bianco S, Chiariello AM, Jerković I, Harabula I, Guckelberger P, Pechstein M, Wittler L, Chan WL, Franke M, Lupiáñez DG, Kraft K, Timmermann B, Vingron M, Visel A, Nicodemi M, Mundlos S, Andrey G.

Nat Genet. 2018 Oct;50(10):1463-1473. doi: 10.1038/s41588-018-0221-x. Epub 2018 Sep 27.

PMID:
30262816
10.

Mechanistic Understanding of Single-Cell Behavior is Essential for Transformative Advances in Biomedicine.

Francis EA, Heinrich V.

Yale J Biol Med. 2018 Sep 21;91(3):279-289. eCollection 2018 Sep. Review.

11.

Stress Distribution Patterns within Viscero- and Neurocranium during Nasoalveolar Molding: a Finite Element Analysis.

Ritschl LM, Heinrich V, Grill FD, Roth M, Hedderich DM, Rau A, Wolff KD, Bauer FX, Loeffelbein DJ.

Plast Reconstr Surg Glob Open. 2018 Jul 17;6(7):e1832. doi: 10.1097/GOX.0000000000001832. eCollection 2018 Jul.

12.

Establishment of a finite element model of a neonate's skull to evaluate the stress pattern distribution resulting during nasoalveolar molding therapy of cleft lip and palate patients.

Bauer FX, Heinrich V, Grill FD, Wölfle F, Hedderich DM, Rau A, Wolff KD, Ritschl LM, Loeffelbein DJ.

J Craniomaxillofac Surg. 2018 Apr;46(4):660-667. doi: 10.1016/j.jcms.2018.01.015. Epub 2018 Feb 2.

PMID:
29545028
13.

Extension of chemotactic pseudopods by nonadherent human neutrophils does not require or cause calcium bursts.

Francis EA, Heinrich V.

Sci Signal. 2018 Mar 13;11(521). pii: eaal4289. doi: 10.1126/scisignal.aal4289.

PMID:
29535263
14.

Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog).

Will AJ, Cova G, Osterwalder M, Chan WL, Wittler L, Brieske N, Heinrich V, de Villartay JP, Vingron M, Klopocki E, Visel A, Lupiáñez DG, Mundlos S.

Nat Genet. 2017 Oct;49(10):1539-1545. doi: 10.1038/ng.3939. Epub 2017 Aug 28.

15.

Analytical Prediction of the Spatiotemporal Distribution of Chemoattractants around Their Source: Theory and Application to Complement-Mediated Chemotaxis.

Heinrich V, Simpson WD 3rd, Francis EA.

Front Immunol. 2017 May 26;8:578. doi: 10.3389/fimmu.2017.00578. eCollection 2017.

16.

Reassessment of Cronobacter spp. originally isolated as Enterobacter sakazakii from infant food.

Akineden Ö, Heinrich V, Gross M, Usleber E.

Food Microbiol. 2017 Aug;65:44-50. doi: 10.1016/j.fm.2017.01.021. Epub 2017 Feb 1.

PMID:
28400018
17.

Quantifying the Sensitivity of Human Immune Cells to Chemoattractant.

Francis EA, Heinrich V.

Biophys J. 2017 Mar 14;112(5):834-837. doi: 10.1016/j.bpj.2017.01.009. Epub 2017 Feb 7.

18.

Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase.

Hurley KA, Santos TMA, Fensterwald MR, Rajendran M, Moore JT, Balmond EI, Blahnik BJ, Faulkner KC, Foss MH, Heinrich VA, Lammers MG, Moore LC, Reynolds GD, Shearn-Nance GP, Stearns BA, Yao ZW, Shaw JT, Weibel DB.

Medchemcomm. 2017;8(5):942-951. doi: 10.1039/C7MD00012J. Epub 2017 Feb 27.

19.

Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin folding.

Andrey G, Schöpflin R, Jerković I, Heinrich V, Ibrahim DM, Paliou C, Hochradel M, Timmermann B, Haas S, Vingron M, Mundlos S.

Genome Res. 2017 Feb;27(2):223-233. doi: 10.1101/gr.213066.116. Epub 2016 Dec 6.

20.

Formation of new chromatin domains determines pathogenicity of genomic duplications.

Franke M, Ibrahim DM, Andrey G, Schwarzer W, Heinrich V, Schöpflin R, Kraft K, Kempfer R, Jerković I, Chan WL, Spielmann M, Timmermann B, Wittler L, Kurth I, Cambiaso P, Zuffardi O, Houge G, Lambie L, Brancati F, Pombo A, Vingron M, Spitz F, Mundlos S.

Nature. 2016 Oct 13;538(7624):265-269. doi: 10.1038/nature19800. Epub 2016 Oct 5.

PMID:
27706140
21.

A likelihood ratio-based method to predict exact pedigrees for complex families from next-generation sequencing data.

Heinrich V, Kamphans T, Mundlos S, Robinson PN, Krawitz PM.

Bioinformatics. 2017 Jan 1;33(1):72-78. doi: 10.1093/bioinformatics/btw550. Epub 2016 Aug 26.

22.

Atrial natriuretic peptide down-regulates neutrophil recruitment on inflamed endothelium by reducing cell deformability and resistance to detachment force.

Morikis VA, Radecke C, Jiang Y, Heinrich V, Curry FR, Simon SI.

Biorheology. 2016 Jul 4;53(2):109. doi: 10.3233/BIR-15067A. No abstract available.

PMID:
27392827
23.

Previous Homologous and Heterologous Stress Exposure Induces Tolerance Development to Pulsed Light in Listeria monocytogenes.

Heinrich V, Zunabovic M, Petschnig A, Müller H, Lassenberger A, Reimhult E, Kneifel W.

Front Microbiol. 2016 Apr 8;7:490. doi: 10.3389/fmicb.2016.00490. eCollection 2016.

24.

Phenolic acid degradation potential and growth behavior of lactic acid bacteria in sunflower substrates.

Fritsch C, Heinrich V, Vogel RF, Toelstede S.

Food Microbiol. 2016 Aug;57:178-86. doi: 10.1016/j.fm.2016.03.003. Epub 2016 Mar 4.

PMID:
27052717
25.

Long-term local control and survival after preoperative radiochemotherapy in combination with deep regional hyperthermia in locally advanced rectal cancer.

Gani C, Schroeder C, Heinrich V, Spillner P, Lamprecht U, Berger B, Zips D.

Int J Hyperthermia. 2016;32(2):187-92. doi: 10.3109/02656736.2015.1117661. Epub 2016 Jan 11.

PMID:
26754458
26.

Atrial natriuretic peptide down-regulates neutrophil recruitment on inflamed endothelium by reducing cell deformability and resistance to detachment force.

Morikis VA, Radecke C, Jiang Y, Heinrich V, Curry FR, Simon SI.

Biorheology. 2015;52(5-6):447-63. doi: 10.3233/BIR-15067.

27.

Effects of Group Psychotherapy, Individual Counseling, Methylphenidate, and Placebo in the Treatment of Adult Attention-Deficit/Hyperactivity Disorder: A Randomized Clinical Trial.

Philipsen A, Jans T, Graf E, Matthies S, Borel P, Colla M, Gentschow L, Langner D, Jacob C, Groß-Lesch S, Sobanski E, Alm B, Schumacher-Stien M, Roesler M, Retz W, Retz-Junginger P, Kis B, Abdel-Hamid M, Heinrich V, Huss M, Kornmann C, Bürger A, Perlov E, Ihorst G, Schlander M, Berger M, Tebartz van Elst L; Comparison of Methylphenidate and Psychotherapy in Adult ADHD Study (COMPAS) Consortium.

JAMA Psychiatry. 2015 Dec;72(12):1199-210. doi: 10.1001/jamapsychiatry.2015.2146. Erratum in: JAMA Psychiatry. 2016 Jan;73(1):90.

PMID:
26536057
28.

Phase III Study of Surgery Versus Definitive Concurrent Chemoradiotherapy Boost in Patients With Resectable Stage IIIA(N2) and Selected IIIB Non-Small-Cell Lung Cancer After Induction Chemotherapy and Concurrent Chemoradiotherapy (ESPATUE).

Eberhardt WE, Pöttgen C, Gauler TC, Friedel G, Veit S, Heinrich V, Welter S, Budach W, Spengler W, Kimmich M, Fischer B, Schmidberger H, De Ruysscher D, Belka C, Cordes S, Hepp R, Lütke-Brintrup D, Lehmann N, Schuler M, Jöckel KH, Stamatis G, Stuschke M.

J Clin Oncol. 2015 Dec 10;33(35):4194-201. doi: 10.1200/JCO.2015.62.6812. Epub 2015 Nov 2.

PMID:
26527789
29.

Strategies to improve the performance of rare variant association studies by optimizing the selection of controls.

Zhu N, Heinrich V, Dickhaus T, Hecht J, Robinson PN, Mundlos S, Kamphans T, Krawitz PM.

Bioinformatics. 2015 Nov 15;31(22):3577-83. doi: 10.1093/bioinformatics/btv457. Epub 2015 Aug 6.

PMID:
26249812
30.

Controlled One-on-One Encounters between Immune Cells and Microbes Reveal Mechanisms of Phagocytosis.

Heinrich V.

Biophys J. 2015 Aug 4;109(3):469-76. doi: 10.1016/j.bpj.2015.06.042. Review.

31.

Regional hyperthermia and moderately dose-escalated salvage radiotherapy for recurrent prostate cancer. Protocol of a phase II trial.

Müller AC, Zips D, Heinrich V, Lamprecht U, Voigt O, Burock S, Budach V, Wust P, Ghadjar P.

Radiat Oncol. 2015 Jul 8;10:138. doi: 10.1186/s13014-015-0442-4.

32.

Continuing harmonization of terminology and innovations for methodologies in developmental toxicology: Report of the 8th Berlin Workshop on Developmental Toxicity, 14-16 May 2014.

Solecki R, Rauch M, Gall A, Buschmann J, Clark R, Fuchs A, Kan H, Heinrich V, Kellner R, Knudsen TB, Li W, Makris SL, Ooshima Y, Paumgartten F, Piersma AH, Schönfelder G, Oelgeschläger M, Schaefer C, Shiota K, Ulbrich B, Ding X, Chahoud I.

Reprod Toxicol. 2015 Nov;57:140-6. doi: 10.1016/j.reprotox.2015.06.046. Epub 2015 Jun 11.

PMID:
26073002
33.

Coccidioides Endospores and Spherules Draw Strong Chemotactic, Adhesive, and Phagocytic Responses by Individual Human Neutrophils.

Lee CY, Thompson GR 3rd, Hastey CJ, Hodge GC, Lunetta JM, Pappagianis D, Heinrich V.

PLoS One. 2015 Jun 12;10(6):e0129522. doi: 10.1371/journal.pone.0129522. eCollection 2015.

34.

Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions.

Lupiáñez DG, Kraft K, Heinrich V, Krawitz P, Brancati F, Klopocki E, Horn D, Kayserili H, Opitz JM, Laxova R, Santos-Simarro F, Gilbert-Dussardier B, Wittler L, Borschiwer M, Haas SA, Osterwalder M, Franke M, Timmermann B, Hecht J, Spielmann M, Visel A, Mundlos S.

Cell. 2015 May 21;161(5):1012-1025. doi: 10.1016/j.cell.2015.04.004. Epub 2015 May 7.

35.

Membrane-Targeting DCAP Analogues with Broad-Spectrum Antibiotic Activity against Pathogenic Bacteria.

Hurley KA, Heinrich VA, Hershfield JR, Demons ST, Weibel DB.

ACS Med Chem Lett. 2015 Mar 1;6(4):466-71. doi: 10.1021/acsmedchemlett.5b00024. eCollection 2015 Apr 9.

36.

Non-invasive spectroscopic determination of the antioxidative status of gravidae and neonates.

Lademann H, Gerber B, Olbertz DM, Darvin ME, Stauf L, Ueberholz K, Heinrich V, Lademann J, Briese V.

Skin Pharmacol Physiol. 2015;28(4):189-95. doi: 10.1159/000365520. Epub 2015 Jan 22.

PMID:
25612614
37.

Pulsed Light Treatment of Different Food Types with a Special Focus on Meat: A Critical Review.

Heinrich V, Zunabovic M, Varzakas T, Bergmair J, Kneifel W.

Crit Rev Food Sci Nutr. 2016;56(4):591-613. doi: 10.1080/10408398.2013.826174. Review.

PMID:
25575192
38.

Homozygous and compound-heterozygous mutations in TGDS cause Catel-Manzke syndrome.

Ehmke N, Caliebe A, Koenig R, Kant SG, Stark Z, Cormier-Daire V, Wieczorek D, Gillessen-Kaesbach G, Hoff K, Kawalia A, Thiele H, Altmüller J, Fischer-Zirnsak B, Knaus A, Zhu N, Heinrich V, Huber C, Harabula I, Spielmann M, Horn D, Kornak U, Hecht J, Krawitz PM, Nürnberg P, Siebert R, Manzke H, Mundlos S.

Am J Hum Genet. 2014 Dec 4;95(6):763-70. doi: 10.1016/j.ajhg.2014.11.004.

39.

Screening for single nucleotide variants, small indels and exon deletions with a next-generation sequencing based gene panel approach for Usher syndrome.

Krawitz PM, Schiska D, Krüger U, Appelt S, Heinrich V, Parkhomchuk D, Timmermann B, Millan JM, Robinson PN, Mundlos S, Hecht J, Gross M.

Mol Genet Genomic Med. 2014 Sep;2(5):393-401. doi: 10.1002/mgg3.92. Epub 2014 Jun 15.

40.

Somatic neurofibromatosis type 1 (NF1) inactivation events in cutaneous neurofibromas of a single NF1 patient.

Emmerich D, Zemojtel T, Hecht J, Krawitz P, Spielmann M, Kühnisch J, Kobus K, Osswald M, Heinrich V, Berlien P, Müller U, Mautner VF, Wimmer K, Robinson PN, Vingron M, Tinschert S, Mundlos S, Kolanczyk M.

Eur J Hum Genet. 2015 Jun;23(6):870-3. doi: 10.1038/ejhg.2014.210. Epub 2014 Oct 8.

41.

The Vi capsular polysaccharide enables Salmonella enterica serovar typhi to evade microbe-guided neutrophil chemotaxis.

Wangdi T, Lee CY, Spees AM, Yu C, Kingsbury DD, Winter SE, Hastey CJ, Wilson RP, Heinrich V, Bäumler AJ.

PLoS Pathog. 2014 Aug 7;10(8):e1004306. doi: 10.1371/journal.ppat.1004306. eCollection 2014 Aug.

42.

Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish.

Hruscha A, Krawitz P, Rechenberg A, Heinrich V, Hecht J, Haass C, Schmid B.

Development. 2013 Dec;140(24):4982-7. doi: 10.1242/dev.099085. Epub 2013 Nov 20.

43.

Acute tryptophan depletion - converging evidence for decreasing central nervous serotonin synthesis in rodents and humans.

Zepf FD, Sánchez CL, Biskup CS, Kötting WF, Bubenzer S, Helmbold K, Eisert A, Gaber TJ, Landgraf M, Dahmen B, Poustka F, Wöckel L, Stadler C, Grabemann M, Mette C, Heinrich V, Uekermann J, Abdel-Hamid M, Kis B, Zimmermann M, Wiltfang J, Kuhn CM.

Acta Psychiatr Scand. 2014 Feb;129(2):157-9. doi: 10.1111/acps.12215. Epub 2013 Nov 18. No abstract available.

PMID:
24237607
44.

A randomized controlled multicenter trial on the multimodal treatment of adult attention-deficit hyperactivity disorder: enrollment and characteristics of the study sample.

Philipsen A, Graf E, Jans T, Matthies S, Borel P, Colla M, Gentschow L, Langner D, Jacob C, Groß-Lesch S, Sobanski E, Alm B, Schumacher-Stien M, Roesler M, Retz W, Retz-Junginger P, Kis B, Abdel-Hamid M, Heinrich V, Huss M, Kornmann C, Bürger A, van Elst LT, Berger M.

Atten Defic Hyperact Disord. 2014 Mar;6(1):35-47. doi: 10.1007/s12402-013-0120-z. Epub 2013 Oct 17.

PMID:
24132867
45.

Filtering for compound heterozygous sequence variants in non-consanguineous pedigrees.

Kamphans T, Sabri P, Zhu N, Heinrich V, Mundlos S, Robinson PN, Parkhomchuk D, Krawitz PM.

PLoS One. 2013 Aug 5;8(8):e70151. doi: 10.1371/journal.pone.0070151. Print 2013.

46.

Estimating exome genotyping accuracy by comparing to data from large scale sequencing projects.

Heinrich V, Kamphans T, Stange J, Parkhomchuk D, Hecht J, Dickhaus T, Robinson PN, Krawitz PM.

Genome Med. 2013 Jul 31;5(7):69. doi: 10.1186/gm473. eCollection 2013.

47.

The role of radiotherapy in the overall treatment of melanoma.

Forschner A, Heinrich V, Pflugfelder A, Meier F, Garbe C.

Clin Dermatol. 2013 May-Jun;31(3):282-9. doi: 10.1016/j.clindermatol.2012.08.009. Review.

PMID:
23608447
48.

No clear effects of acute tryptophan depletion on processing affective prosody in male adults with ADHD.

Grabemann M, Mette C, Zimmermann M, Heinrich V, Uekermann J, Wiltfang J, Abdel-Hamid M, Zepf FD, Kis B.

Acta Psychiatr Scand. 2013 Aug;128(2):142-8. doi: 10.1111/acps.12130. Epub 2013 Apr 13.

PMID:
23581825
49.

Differential effects of serum heat treatment on chemotaxis and phagocytosis by human neutrophils.

Mankovich AR, Lee CY, Heinrich V.

PLoS One. 2013;8(1):e54735. doi: 10.1371/journal.pone.0054735. Epub 2013 Jan 22.

50.

Harmonization of description and classification of fetal observations: achievements and problems still unresolved: report of the 7th Workshop on the Terminology in Developmental Toxicology Berlin, 4-6 May 2011.

Solecki R, Barbellion S, Bergmann B, Bürgin H, Buschmann J, Clark R, Comotto L, Fuchs A, Faqi AS, Gerspach R, Grote K, Hakansson H, Heinrich V, Heinrich-Hirsch B, Hofmann T, Hübel U, Inazaki TH, Khalil S, Knudsen TB, Kudicke S, Lingk W, Makris S, Müller S, Paumgartten F, Pfeil R, Rama EM, Schneider S, Shiota K, Tamborini E, Tegelenbosch M, Ulbrich B, van Duijnhoven EA, Wise D, Chahoud I.

Reprod Toxicol. 2013 Jan;35:48-55. doi: 10.1016/j.reprotox.2012.06.006. Epub 2012 Jul 8.

PMID:
22781580

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