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Items: 1 to 50 of 93

1.

Concomitant Transapical Transcatheter Aortic Valve Implantation and Transapical Mitral Valve Repair with NeoChord Implantation.

Stelzmueller ME, Zilberszac R, Heinrich N, Mora B, Laufer G, Wisser W.

Innovations (Phila). 2019 Sep 16:1556984519871905. doi: 10.1177/1556984519871905. [Epub ahead of print]

PMID:
31524023
2.

Ultrasensitive Detection of Salmonella and Listeria monocytogenes by Small-Molecule Chemiluminescence Probes.

Roth-Konforti M, Green O, Hupfeld M, Fieseler L, Heinrich N, Ihssen J, Vorberg R, Wick L, Spitz U, Shabat D.

Angew Chem Int Ed Engl. 2019 Jul 22;58(30):10361-10367. doi: 10.1002/anie.201904719. Epub 2019 Jun 24. Review.

PMID:
31233265
3.

Seroepidemiological and molecular investigations of infections with Crimean-Congo haemorrhagic fever virus in Kazakhstan.

Abdiyeva K, Turebekov N, Dmitrovsky A, Tukhanova N, Shin A, Yeraliyeva L, Heinrich N, Hoelscher M, Yegemberdiyeva R, Shapiyeva Z, Kachiyeva Z, Zhalmagambetova A, Montag J, Dobler G, Zinner J, Wagner E, Frey S, Essbauer S.

Int J Infect Dis. 2019 Jan;78:121-127. doi: 10.1016/j.ijid.2018.10.015. Epub 2018 Oct 25.

4.

Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy.

Ahmed MIM, Ntinginya NE, Kibiki G, Mtafya BA, Semvua H, Mpagama S, Mtabho C, Saathoff E, Held K, Loose R, Kroidl I, Chachage M, von Both U, Haule A, Mekota AM, Boeree MJ, Gillespie SH, Hoelscher M, Heinrich N, Geldmacher C.

Front Immunol. 2018 Sep 28;9:2247. doi: 10.3389/fimmu.2018.02247. eCollection 2018.

5.

The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis.

Svensson EM, Svensson RJ, Te Brake LHM, Boeree MJ, Heinrich N, Konsten S, Churchyard G, Dawson R, Diacon AH, Kibiki GS, Minja LT, Ntingiya NE, Sanne I, Gillespie SH, Hoelscher M, Phillips PPJ, Simonsson USH, Aarnoutse R.

Clin Infect Dis. 2018 Jun 18;67(1):34-41. doi: 10.1093/cid/ciy026.

6.

Seroepidemiological Studies of Arboviruses in Africa.

Gudo ES, Ali S, António VS, Chelene IR, Chongo I, Demanou M, Falk K, Guiliche OC, Heinrich N, Monteiro V, Muianga AF, Oludele J, Mula F, Mutuku F, Amade N, Alho P, Betsem E, Chimbuinhe Z, Cristovam AJ, Galano G, Gessain A, Harris E, Heise M, Inalda F, Jala I, Jaszi E, King C, Kitron U, Kümmerer BM, LaBeaud AD, Lagerqvist N, Malai G, Mazelier M, Mendes S, Mukoko D, Ndenga B, Njouom R, Pinto G, Tivane A, Vu DM, Vulule J.

Adv Exp Med Biol. 2018;1062:361-371. doi: 10.1007/978-981-10-8727-1_25. Review.

PMID:
29845545
7.

The impact of repeated NALC/NaOH- decontamination on the performance of Xpert MTB/RIF assay.

Rachow A, Saathoff E, Mtafya B, Mapamba D, Mangu C, Rojas-Ponce G, Ntinginya NE, Boeree M, Heinrich N, Gillespie SH, Hoelscher M; PanACEA-Consortium.

Tuberculosis (Edinb). 2018 May;110:56-58. doi: 10.1016/j.tube.2018.04.001. Epub 2018 Apr 5.

PMID:
29779774
8.

Efficiency of different measures for defining the applicability domain of classification models.

Klingspohn W, Mathea M, Ter Laak A, Heinrich N, Baumann K.

J Cheminform. 2017 Aug 3;9(1):44. doi: 10.1186/s13321-017-0230-2.

9.

Proceedings from the CIHLMU 5th Infectious Diseases Symposium 2016 "Drug Resistant Tuberculosis: Old Disease - New Challenge".

Khosa C, Patel K, Abdiyeva K, Turebekov N, Prüller B, Heinrich N.

BMC Proc. 2017 Sep 4;11(Suppl 10):0. doi: 10.1186/s12919-017-0077-6. eCollection 2017.

10.

A double-blinded, randomized, controlled, crossover evaluation of a zinc methionine supplement as an adjunctive treatment for canine atopic dermatitis.

McFadden RA, Heinrich NA, Haarstad AC, Tomlinson DJ.

Vet Dermatol. 2017 Dec;28(6):569-e138. doi: 10.1111/vde.12466. Epub 2017 Jul 23.

PMID:
28736909
11.

Identifying children with tuberculosis among household contacts in The Gambia.

Egere U, Togun T, Sillah A, Mendy F, Otu J, Hoelscher M, Heinrich N, Hill PC, Kampmann B.

Int J Tuberc Lung Dis. 2017 Jan 1;21(1):46-52. doi: 10.5588/ijtld.16.0289.

PMID:
28157464
12.

Isoniazid preventive treatment among child contacts of adults with smear-positive tuberculosis in The Gambia.

Egere U, Sillah A, Togun T, Kandeh S, Cole F, Jallow A, Able-Thomas A, Hoelscher M, Heinrich N, Hill PC, Kampmann B.

Public Health Action. 2016 Dec 21;6(4):226-231. doi: 10.5588/pha.16.0073.

13.

High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial.

Boeree MJ, Heinrich N, Aarnoutse R, Diacon AH, Dawson R, Rehal S, Kibiki GS, Churchyard G, Sanne I, Ntinginya NE, Minja LT, Hunt RD, Charalambous S, Hanekom M, Semvua HH, Mpagama SG, Manyama C, Mtafya B, Reither K, Wallis RS, Venter A, Narunsky K, Mekota A, Henne S, Colbers A, van Balen GP, Gillespie SH, Phillips PPJ, Hoelscher M; PanACEA consortium.

Lancet Infect Dis. 2017 Jan;17(1):39-49. doi: 10.1016/S1473-3099(16)30274-2. Epub 2016 Oct 26.

14.

Drug resistance and population structure of M.tuberculosis isolates from prisons and communities in Ethiopia.

Ali S, Beckert P, Haileamlak A, Wieser A, Pritsch M, Heinrich N, Löscher T, Hoelscher M, Niemann S, Rachow A.

BMC Infect Dis. 2016 Nov 21;16(1):687.

15.

Target Product Profile for a Diagnostic Assay to Differentiate between Bacterial and Non-Bacterial Infections and Reduce Antimicrobial Overuse in Resource-Limited Settings: An Expert Consensus.

Dittrich S, Tadesse BT, Moussy F, Chua A, Zorzet A, Tängdén T, Dolinger DL, Page AL, Crump JA, D'Acremont V, Bassat Q, Lubell Y, Newton PN, Heinrich N, Rodwell TJ, González IJ.

PLoS One. 2016 Aug 25;11(8):e0161721. doi: 10.1371/journal.pone.0161721. eCollection 2016.

16.

Limited value of whole blood Xpert(®) MTB/RIF for diagnosing tuberculosis in children.

Pohl C, Rutaihwa LK, Haraka F, Nsubuga M, Aloi F, Ntinginya NE, Mapamba D, Heinrich N, Hoelscher M, Marais BJ, Jugheli L, Reither K.

J Infect. 2016 Oct;73(4):326-35. doi: 10.1016/j.jinf.2016.04.041. Epub 2016 Jul 7.

PMID:
27394403
17.

Optimising molecular diagnostic capacity for effective control of tuberculosis in high-burden settings.

Sabiiti W, Mtafya B, Kuchaka D, Azam K, Viegas S, Mdolo A, Farmer EC, Khonga M, Evangelopoulos D, Honeyborne I, Rachow A, Heinrich N, Ntinginya NE, Bhatt N, Davies GR, Jani IV, McHugh TD, Kibiki G, Hoelscher M, Gillespie SH; PANBIOME (Pan-African Biomarker Expansion Programme) consortium.

Int J Tuberc Lung Dis. 2016 Aug;20(8):1004-9. doi: 10.5588/ijtld.15.0951.

PMID:
27393531
18.

A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP).

Phillips PP, Dooley KE, Gillespie SH, Heinrich N, Stout JE, Nahid P, Diacon AH, Aarnoutse RE, Kibiki GS, Boeree MJ, Hoelscher M.

BMC Med. 2016 Mar 23;14:51. doi: 10.1186/s12916-016-0597-3.

19.

Integrating Local, National, and International Stakeholders in Outbreak Preparedness in Developing Countries: Conclusions from a Conference in Mbeya, Tanzania.

Froeschl G, Ntinginya NE, Sangare A, Lawala P, Mangu C, Dobler G, Heinrich N, Flach B, Nsojo A, Lennemann T.

Health Secur. 2016 Jan-Feb;14(1):29-34. doi: 10.1089/hs.2015.0049. Epub 2016 Feb 2.

PMID:
26836445
20.

Prevalence of Pulmonary Tuberculosis among Prison Inmates in Ethiopia, a Cross-Sectional Study.

Ali S, Haileamlak A, Wieser A, Pritsch M, Heinrich N, Loscher T, Hoelscher M, Rachow A.

PLoS One. 2015 Dec 7;10(12):e0144040. doi: 10.1371/journal.pone.0144040. eCollection 2015.

21.

Computational Chemistry in the Pharmaceutical Industry: From Childhood to Adolescence.

Hillisch A, Heinrich N, Wild H.

ChemMedChem. 2015 Dec;10(12):1958-62. doi: 10.1002/cmdc.201500346. Epub 2015 Sep 11.

PMID:
26358802
22.

[Intensive care treatment of patients with left ventricular assist devices].

Steinlechner B, Zimpfer D, Schiferer A, Heinrich N, Schlöglhofer T, Rajek A, Dworschak M, Hiesmayr M.

Med Klin Intensivmed Notfmed. 2015 Sep;110(6):421-30. doi: 10.1007/s00063-015-0063-6. Epub 2015 Aug 28. Review. German.

PMID:
26314348
23.

A Step toward an Optimized Rifampin Dose Completed.

Boeree MJ, Diacon AH, Dawson R, Narunsky K, du Bois J, Venter A, Phillips PP, Gillespie SH, McHugh TD, Hoelscher M, Heinrich N, Rehal S, van Soolingen D, van Ingen J, Magis-Escurra C, Burger D, Plemper van Balen G, Aarnoutse RE.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):525-6. doi: 10.1164/rccm.201506-1061LE. No abstract available.

PMID:
26278799
24.

Early Identification of Progressive TB Disease Using Host Biomarkers.

Rachow A, Heinrich N, Geldmacher C.

EBioMedicine. 2015 Jan 16;2(2):107-8. doi: 10.1016/j.ebiom.2015.01.009. eCollection 2015 Feb. Review. No abstract available.

25.

Performance of urine lipoarabinomannan assays for paediatric tuberculosis in Tanzania.

Kroidl I, Clowes P, Reither K, Mtafya B, Rojas-Ponce G, Ntinginya EN, Kalomo M, Minja LT, Kowuor D, Saathoff E, Kroidl A, Heinrich N, Maboko L, Bates M, O'Grady J, Zumla A, Hoelscher M, Rachow A.

Eur Respir J. 2015 Sep;46(3):761-70. doi: 10.1183/09031936.00003315. Epub 2015 Jun 25.

26.

High seroprevalence for spotted fever group rickettsiae, is associated with higher temperatures and rural environment in Mbeya region, Southwestern Tanzania.

Heinrich N, Dill T, Dobler G, Clowes P, Kroidl I, Starke M, Ntinginya NE, Maboko L, Löscher T, Hoelscher M, Saathoff E.

PLoS Negl Trop Dis. 2015 Apr 7;9(4):e0003626. doi: 10.1371/journal.pntd.0003626. eCollection 2015 Apr.

27.

N-Heterocycles from chromium aminocarbenes.

Déry M, Assouvie K, Heinrich N, Rajotte I, Lefebvre LP, Legault MA, Spino C.

Org Lett. 2015 Mar 6;17(5):1312-5. doi: 10.1021/acs.orglett.5b00313. Epub 2015 Feb 23.

PMID:
25702700
28.

A dose-ranging trial to optimize the dose of rifampin in the treatment of tuberculosis.

Boeree MJ, Diacon AH, Dawson R, Narunsky K, du Bois J, Venter A, Phillips PP, Gillespie SH, McHugh TD, Hoelscher M, Heinrich N, Rehal S, van Soolingen D, van Ingen J, Magis-Escurra C, Burger D, Plemper van Balen G, Aarnoutse RE; PanACEA Consortium.

Am J Respir Crit Care Med. 2015 May 1;191(9):1058-65. doi: 10.1164/rccm.201407-1264OC.

PMID:
25654354
29.

Early phase evaluation of SQ109 alone and in combination with rifampicin in pulmonary TB patients.

Heinrich N, Dawson R, du Bois J, Narunsky K, Horwith G, Phipps AJ, Nacy CA, Aarnoutse RE, Boeree MJ, Gillespie SH, Venter A, Henne S, Rachow A, Phillips PP, Hoelscher M, Diacon AH; Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA); Pan African Consortium for the Evaluation of Antituberculosis Antibiotics PanACEA.

J Antimicrob Chemother. 2015 May;70(5):1558-66. doi: 10.1093/jac/dku553. Epub 2015 Jan 27.

PMID:
25630641
30.

Disappearance of left ventricular hypertrabeculation/noncompaction in vacuolar non-neuromuscular cardiomyopathy.

Stöllberger C, Kolussi T, Hackl M, Mahr S, Heinrich N, Grassberger M, Finsterer J.

Int J Cardiol. 2015 Jan 20;179:5-8. doi: 10.1016/j.ijcard.2014.10.080. Epub 2014 Oct 24. No abstract available.

PMID:
25464391
31.

The relationship between Mycobacterium tuberculosis MGIT time to positivity and cfu in sputum samples demonstrates changing bacterial phenotypes potentially reflecting the impact of chemotherapy on critical sub-populations.

Bowness R, Boeree MJ, Aarnoutse R, Dawson R, Diacon A, Mangu C, Heinrich N, Ntinginya NE, Kohlenberg A, Mtafya B, Phillips PP, Rachow A, Plemper van Balen G, Gillespie SH.

J Antimicrob Chemother. 2015 Feb;70(2):448-55. doi: 10.1093/jac/dku415. Epub 2014 Oct 25.

PMID:
25344806
32.

Methylphenidate and desipramine combined treatment improves PTSD symptomatology in a rat model.

Aga-Mizrachi S, Cymerblit-Sabba A, Gurman O, Balan A, Shwam G, Deshe R, Miller L, Gorodetsky N, Heinrich N, Tzezana O, Zubedat S, Grinstein D, Avital A.

Transl Psychiatry. 2014 Sep 23;4:e447. doi: 10.1038/tp.2014.82.

33.

Semisynthesis and optimization of G protein-coupled receptor mimics.

Abel S, Geltinger B, Heinrich N, Michl D, Klose A, Beyermann M, Schwarzer D.

J Pept Sci. 2014 Nov;20(11):831-6. doi: 10.1002/psc.2680. Epub 2014 Aug 4.

PMID:
25092519
34.

Seroprevalence of alphavirus antibodies in a cross-sectional study in southwestern Tanzania suggests endemic circulation of chikungunya.

Weller N, Clowes P, Dobler G, Saathoff E, Kroidl I, Ntinginya NE, Maboko L, Löscher T, Hoelscher M, Heinrich N.

PLoS Negl Trop Dis. 2014 Jul 31;8(7):e2979. doi: 10.1371/journal.pntd.0002979. eCollection 2014.

35.

The molecular bacterial load assay replaces solid culture for measuring early bactericidal response to antituberculosis treatment.

Honeyborne I, Mtafya B, Phillips PP, Hoelscher M, Ntinginya EN, Kohlenberg A, Rachow A, Rojas-Ponce G, McHugh TD, Heinrich N; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics.

J Clin Microbiol. 2014 Aug;52(8):3064-7. doi: 10.1128/JCM.01128-14. Epub 2014 May 28.

36.

Isolation of bacterial skin flora of healthy sheep, with comparison between frequent and minimal human handling.

Haarstad AC, Eisenschenk MC, Heinrich NA, Weese JS, McKeever PJ.

Vet Dermatol. 2014 Jun;25(3):215-e56. doi: 10.1111/vde.12126.

PMID:
24840328
37.

Assessment of the sensitivity and specificity of Xpert MTB/RIF assay as an early sputum biomarker of response to tuberculosis treatment.

Friedrich SO, Rachow A, Saathoff E, Singh K, Mangu CD, Dawson R, Phillips PP, Venter A, Bateson A, Boehme CC, Heinrich N, Hunt RD, Boeree MJ, Zumla A, McHugh TD, Gillespie SH, Diacon AH, Hoelscher M; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics (PanACEA).

Lancet Respir Med. 2013 Aug;1(6):462-70. doi: 10.1016/S2213-2600(13)70119-X. Epub 2013 Jul 1.

38.

miRNA signatures in sera of patients with active pulmonary tuberculosis.

Miotto P, Mwangoka G, Valente IC, Norbis L, Sotgiu G, Bosu R, Ambrosi A, Codecasa LR, Goletti D, Matteelli A, Ntinginya EN, Aloi F, Heinrich N, Reither K, Cirillo DM.

PLoS One. 2013 Nov 21;8(11):e80149. doi: 10.1371/journal.pone.0080149. eCollection 2013.

39.

A continuously monitored colorimetric method for detection of Mycobacterium tuberculosis complex in sputum.

Rojas-Ponce G, Rachow A, Guerra H, Mapamba D, Joseph J, Mlundi R, Marimoto S, Ntinginya NE, Mangu C, Framhein A, Butler A, Kohlenberg A, Ngatemelela D, Froeschl G, Maboko L, Hoelscher M, Heinrich N.

Int J Tuberc Lung Dis. 2013 Dec;17(12):1607-12. doi: 10.5588/ijtld.13.0317.

PMID:
24200277
40.

Direct comparison of Xpert MTB/RIF assay with liquid and solid mycobacterial culture for quantification of early bactericidal activity.

Kayigire XA, Friedrich SO, Venter A, Dawson R, Gillespie SH, Boeree MJ, Heinrich N, Hoelscher M, Diacon AH; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics.

J Clin Microbiol. 2013 Jun;51(6):1894-8. doi: 10.1128/JCM.03290-12. Epub 2013 Apr 17.

41.

High seroprevalence for typhus group rickettsiae, southwestern Tanzania.

Dill T, Dobler G, Saathoff E, Clowes P, Kroidl I, Ntinginya E, Machibya H, Maboko L, Löscher T, Hoelscher M, Heinrich N.

Emerg Infect Dis. 2013 Feb;19(2):317-20. doi: 10.3201/eid1902.120601.

42.

Pharmacology and clinical use of sex steroid hormone receptor modulators.

Cleve A, Fritzemeier KH, Haendler B, Heinrich N, Möller C, Schwede W, Wintermantel T.

Handb Exp Pharmacol. 2012;(214):543-87. doi: 10.1007/978-3-642-30726-3_24. Review.

PMID:
23027466
43.

Reversible cyclopropane ring-cleavage reactions within etheno-bridged [4.3.1]propelladiene frameworks leading to aza- and oxa-[5.6.5.6]fenestratetraenes.

Heinrich N, Willis AC, Cade IA, Ho J, Coote ML, Banwell MG.

Chemistry. 2012 Oct 22;18(43):13585-8. doi: 10.1002/chem.201202903. Epub 2012 Sep 17.

PMID:
22987604
44.

Performance of the Xpert® MTB/RIF assay in an active case-finding strategy: a pilot study from Tanzania.

Ntinginya EN, Squire SB, Millington KA, Mtafya B, Saathoff E, Heinrich N, Rojas-Ponce G, Kowuor D, Maboko L, Reither K, Clowes P, Hoelscher M, Rachow A.

Int J Tuberc Lung Dis. 2012 Nov;16(11):1468-70. doi: 10.5588/ijtld.12.0127. Epub 2012 Sep 7.

PMID:
22964006
45.

A case of disseminated tuberculosis with psoas abscess in a 12-year-old girl with sickle cell trait.

Heinrich N, Prusseit J, Born M, Fleischhack G, Simon A.

Klin Padiatr. 2012 Apr;224(3):195-6. doi: 10.1055/s-0032-1308985. Epub 2012 Apr 13. No abstract available.

PMID:
22504772
46.

High seroprevalence of Rift Valley FEVER AND EVIDENCE FOR ENDEMIC circulation in Mbeya region, Tanzania, in a cross-sectional study.

Heinrich N, Saathoff E, Weller N, Clowes P, Kroidl I, Ntinginya E, Machibya H, Maboko L, Löscher T, Dobler G, Hoelscher M.

PLoS Negl Trop Dis. 2012;6(3):e1557. doi: 10.1371/journal.pntd.0001557. Epub 2012 Mar 27.

47.

Evaluation of tuberculosis diagnostics in children: 2. Methodological issues for conducting and reporting research evaluations of tuberculosis diagnostics for intrathoracic tuberculosis in children. Consensus from an expert panel.

Cuevas LE, Browning R, Bossuyt P, Casenghi M, Cotton MF, Cruz AT, Dodd LE, Drobniewski F, Gale M, Graham SM, Grzemska M, Heinrich N, Hesseling AC, Huebner R, Jean-Philippe P, Kabra SK, Kampmann B, Lewinsohn D, Li M, Lienhardt C, Mandalakas AM, Marais BJ, Menzies HJ, Montepiedra G, Mwansambo C, Oberhelman R, Palumbo P, Russek-Cohen E, Shapiro DE, Smith B, Soto-Castellares G, Starke JR, Swaminathan S, Wingfield C, Worrell C.

J Infect Dis. 2012 May 15;205 Suppl 2:S209-15. doi: 10.1093/infdis/jir879. Epub 2012 Apr 3.

48.

Increased and expedited case detection by Xpert MTB/RIF assay in childhood tuberculosis: a prospective cohort study.

Rachow A, Clowes P, Saathoff E, Mtafya B, Michael E, Ntinginya EN, Kowour D, Rojas-Ponce G, Kroidl A, Maboko L, Heinrich N, Reither K, Hoelscher M.

Clin Infect Dis. 2012 May;54(10):1388-96. doi: 10.1093/cid/cis190. Epub 2012 Apr 3.

PMID:
22474220
49.

Innovative trial designs are practical solutions for improving the treatment of tuberculosis.

Phillips PP, Gillespie SH, Boeree M, Heinrich N, Aarnoutse R, McHugh T, Pletschette M, Lienhardt C, Hafner R, Mgone C, Zumla A, Nunn AJ, Hoelscher M.

J Infect Dis. 2012 May 15;205 Suppl 2:S250-7. doi: 10.1093/infdis/jis041. Epub 2012 Mar 22.

PMID:
22448027
50.

Photoswitchable click amino acids: light control of conformation and bioactivity.

Hoppmann C, Schmieder P, Heinrich N, Beyermann M.

Chembiochem. 2011 Nov 25;12(17):2555-9. doi: 10.1002/cbic.201100578. Epub 2011 Oct 13.

PMID:
21998087

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