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Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs).

Heinrich MC, Patterson J, Beadling C, Wang Y, Debiec-Rychter M, Dewaele B, Corless CL, Duensing A, Raut CP, Rubin B, Ordog T, van de Rijn M, Call J, Mühlenberg T, Fletcher JA, Bauer S.

Clin Sarcoma Res. 2019 Mar 5;9:3. doi: 10.1186/s13569-019-0112-7. eCollection 2019.


Endogenous double-stranded Alu RNA elements stimulate IFN-responses in relapsing remitting multiple sclerosis.

Heinrich MJ, Purcell CA, Pruijssers AJ, Zhao Y, Spurlock CF 3rd, Sriram S, Ogden KM, Dermody TS, Scholz MB, Crooke PS 3rd, Karijolich J, Aune TM.

J Autoimmun. 2019 Feb 27. pii: S0896-8411(18)30699-1. doi: 10.1016/j.jaut.2019.02.003. [Epub ahead of print]


Neuroanatomical correlates of food addiction symptoms and body mass index in the general population.

Beyer F, García-García I, Heinrich M, Schroeter ML, Sacher J, Luck T, Riedel-Heller SG, Stumvoll M, Villringer A, Witte AV.

Hum Brain Mapp. 2019 Feb 28. doi: 10.1002/hbm.24557. [Epub ahead of print]


OBELISK-Net: Fewer layers to solve 3D multi-organ segmentation with sparse deformable convolutions.

Heinrich MP, Oktay O, Bouteldja N.

Med Image Anal. 2019 Feb 13;54:1-9. doi: 10.1016/ [Epub ahead of print]


Attention gated networks: Learning to leverage salient regions in medical images.

Schlemper J, Oktay O, Schaap M, Heinrich M, Kainz B, Glocker B, Rueckert D.

Med Image Anal. 2019 Apr;53:197-207. doi: 10.1016/ Epub 2019 Feb 5.


Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours.

Serrano C, Mariño-Enríquez A, Tao DL, Ketzer J, Eilers G, Zhu M, Yu C, Mannan AM, Rubin BP, Demetri GD, Raut CP, Presnell A, McKinley A, Heinrich MC, Czaplinski JT, Sicinska E, Bauer S, George S, Fletcher JA.

Br J Cancer. 2019 Mar;120(6):612-620. doi: 10.1038/s41416-019-0389-6. Epub 2019 Feb 22.


St. John's Wort (Hypericum perforatum) Products - How Variable Is the Primary Material?

Scotti F, Löbel K, Booker A, Heinrich M.

Front Plant Sci. 2019 Jan 24;9:1973. doi: 10.3389/fpls.2018.01973. eCollection 2018.


3D-Bioprinted Mini-Brain: A Glioblastoma Model to Study Cellular Interactions and Therapeutics.

Heinrich MA, Bansal R, Lammers T, Zhang YS, Michel Schiffelers R, Prakash J.

Adv Mater. 2019 Jan 31:e1806590. doi: 10.1002/adma.201806590. [Epub ahead of print]


Mixed-methods approach to exploring patients' perspectives on the acceptability of a urinary biomarker test in replacing cystoscopy for bladder cancer surveillance.

Tan WS, Teo CH, Chan D, Heinrich M, Feber A, Sarpong R, Allan J, Williams N, Brew-Graves C, Ng CJ, Kelly JD; DETECT II trial collaborators.

BJU Int. 2019 Jan 29. doi: 10.1111/bju.14690. [Epub ahead of print]


Demonstration of a two-dimensional [Formula: see text]-symmetric crystal.

Kremer M, Biesenthal T, Maczewsky LJ, Heinrich M, Thomale R, Szameit A.

Nat Commun. 2019 Jan 25;10(1):435. doi: 10.1038/s41467-018-08104-x.


Selective Functionalization of Graphene at Defect-Activated Sites by Arylazocarboxylic tert-Butyl Esters.

Halbig CE, Lasch R, Krüll J, Pirzer AS, Wang Z, Kirchhof JN, Bolotin KI, Heinrich MR, Eigler S.

Angew Chem Int Ed Engl. 2019 Mar 11;58(11):3599-3603. doi: 10.1002/anie.201811192. Epub 2019 Jan 25.


High expression of class III β-tubulin in upper gastrointestinal cancer types.

Höflmayer D, Öztürk E, Schroeder C, Hube-Magg C, Blessin NC, Simon R, Lang DS, Neubauer E, Göbel C, Heinrich MC, Fraune C, Möller K, Armbrust M, Freytag M, Hinsch A, Lühr C, Noack M, Reiswich V, Weidemann S, Bockhorn M, Perez D, Izbicki JR, Sauter G, Jacobsen F.

Oncol Lett. 2018 Dec;16(6):7139-7145. doi: 10.3892/ol.2018.9502. Epub 2018 Sep 25.


Dose-Dependent Effects of Closed-Loop tACS Delivered During Slow-Wave Oscillations on Memory Consolidation.

Jones AP, Choe J, Bryant NB, Robinson CSH, Ketz NA, Skorheim SW, Combs A, Lamphere ML, Robert B, Gill HA, Heinrich MD, Howard MD, Clark VP, Pilly PK.

Front Neurosci. 2018 Nov 27;12:867. doi: 10.3389/fnins.2018.00867. eCollection 2018.


The importance of pancreatic inflammation in endosonographic diagnostics of solid pancreatic masses.

Vitali F, Strobel D, Frulloni L, Heinrich M, Pfeifer L, Goertz RS, Hundorfean G, Wachter DL, Gruetzmann R, Bernatik T, Neurath MF, Wildner D.

Med Ultrason. 2018 Dec 8;20(4):427-435. doi: 10.11152/mu-1641.


Learning to Predict Ischemic Stroke Growth on Acute CT Perfusion Data by Interpolating Low-Dimensional Shape Representations.

Lucas C, Kemmling A, Bouteldja N, Aulmann LF, Madany Mamlouk A, Heinrich MP.

Front Neurol. 2018 Nov 26;9:989. doi: 10.3389/fneur.2018.00989. eCollection 2018.


A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model.

Zhang Y, Lane ME, Hadgraft J, Heinrich M, Chen T, Lian G, Sinko B.

Int J Pharm. 2019 Feb 10;556:142-149. doi: 10.1016/j.ijpharm.2018.11.065. Epub 2018 Dec 6.


In Situ Conformational Fixation of the Amide Bond Enables General Access to Medium-Sized Lactams via Ring-Closing Metathesis.

Hegmann N, Prusko L, Diesendorf N, Heinrich MR.

Org Lett. 2018 Dec 11. doi: 10.1021/acs.orglett.8b03320. [Epub ahead of print]


Radical Carbofluorination of Alkenes with Arylhydrazines and Selectfluor: Additives, Mechanistic Pathways, and Polar Effects.

Pirzer AS, Alvarez EM, Friedrich H, Heinrich MR.

Chemistry. 2019 Feb 21;25(11):2786-2792. doi: 10.1002/chem.201805256. Epub 2019 Jan 25.


Autonomously shaping natural climbing plants: a bio-hybrid approach.

Wahby M, Heinrich MK, Hofstadler DN, Neufeld E, Kuksin I, Zahadat P, Schmickl T, Ayres P, Hamann H.

R Soc Open Sci. 2018 Oct 24;5(10):180296. doi: 10.1098/rsos.180296. eCollection 2018 Oct.


Enantioselective Synthesis of des-epoxy-Amphidinolide N.

Trost BM, Bai WJ, Stivala CE, Hohn C, Poock C, Heinrich M, Xu S, Rey J.

J Am Chem Soc. 2018 Nov 20. doi: 10.1021/jacs.8b11827. [Epub ahead of print]


Combining MRF-based deformable registration and deep binary 3D-CNN descriptors for large lung motion estimation in COPD patients.

Blendowski M, Heinrich MP.

Int J Comput Assist Radiol Surg. 2019 Jan;14(1):43-52. doi: 10.1007/s11548-018-1888-2. Epub 2018 Nov 14.


Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists.

Liu H, Hofmann J, Fish I, Schaake B, Eitel K, Bartuschat A, Kaindl J, Rampp H, Banerjee A, Hübner H, Clark MJ, Vincent SG, Fisher JT, Heinrich MR, Hirata K, Liu X, Sunahara RK, Shoichet BK, Kobilka BK, Gmeiner P.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):12046-12050. doi: 10.1073/pnas.1813988115. Epub 2018 Nov 7.


[Autism spectrum disorders in adults with intellectual disabilities : Frequencies and characteristics].

Böhm J, Diefenbacher A, Heinrich M, Sappok T.

Nervenarzt. 2018 Oct 30. doi: 10.1007/s00115-018-0635-9. [Epub ahead of print] German.


Siddha Medicine in Eastern Sri Lanka Today-Continuity and Change in the Treatment of Diabetes.

Sathasivampillai SV, Rajamanoharan PRS, Heinrich M.

Front Pharmacol. 2018 Oct 10;9:1022. doi: 10.3389/fphar.2018.01022. eCollection 2018.


[Reduction of treatment time for children in the trauma room care : Impact of implementation of an interdisciplinary trauma room concept (iTRAPS)].

Lehner M, Hoffmann F, Kammer B, Heinrich M, Falkenthal L, Wendling-Keim D, Kurz M.

Anaesthesist. 2018 Dec;67(12):914-921. doi: 10.1007/s00101-018-0500-z. Epub 2018 Oct 25. German.


Comparative Immunomodulatory Activity of Nigella sativa L. Preparations on Proinflammatory Mediators: A Focus on Asthma.

Koshak AE, Yousif NM, Fiebich BL, Koshak EA, Heinrich M.

Front Pharmacol. 2018 Oct 2;9:1075. doi: 10.3389/fphar.2018.01075. eCollection 2018.


25 years after the `Rio Convention'--Lessons learned in the context of sustainable development and protecting indigenous and local knowledge.

Heinrich M, Hesketh A.

Phytomedicine. 2019 Feb;53:332-343. doi: 10.1016/j.phymed.2018.04.061. Epub 2018 May 10. Review.


Giving G a Meaning: An Application of the Bifactor-(S-1) Approach to Realize a More Symptom-Oriented Modeling of the Beck Depression Inventory-II.

Heinrich M, Zagorscak P, Eid M, Knaevelsrud C.

Assessment. 2018 Oct 6:1073191118803738. doi: 10.1177/1073191118803738. [Epub ahead of print]


Reply to the Letter by Singer, Mitter, and Porsch Related to Our Paper "Benefits of Individualized Feedback in Internet-Based Interventions for Depression: A Randomized Controlled Trial".

Zagorscak P, Heinrich M, Sommer D, Wagner B, Knaevelsrud C.

Psychother Psychosom. 2018;87(6):367-368. doi: 10.1159/000493394. Epub 2018 Oct 1. No abstract available.


ISLES 2016 and 2017-Benchmarking Ischemic Stroke Lesion Outcome Prediction Based on Multispectral MRI.

Winzeck S, Hakim A, McKinley R, Pinto JAADSR, Alves V, Silva C, Pisov M, Krivov E, Belyaev M, Monteiro M, Oliveira A, Choi Y, Paik MC, Kwon Y, Lee H, Kim BJ, Won JH, Islam M, Ren H, Robben D, Suetens P, Gong E, Niu Y, Xu J, Pauly JM, Lucas C, Heinrich MP, Rivera LC, Castillo LS, Daza LA, Beers AL, Arbelaezs P, Maier O, Chang K, Brown JM, Kalpathy-Cramer J, Zaharchuk G, Wiest R, Reyes M.

Front Neurol. 2018 Sep 13;9:679. doi: 10.3389/fneur.2018.00679. eCollection 2018.


LMTK3 is essential for oncogenic KIT expression in KIT-mutant GIST and melanoma.

Klug LR, Bannon AE, Javidi-Sharifi N, Town A, Fleming WH, VanSlyke JK, Musil LS, Fletcher JA, Tyner JW, Heinrich MC.

Oncogene. 2019 Feb;38(8):1200-1210. doi: 10.1038/s41388-018-0508-5. Epub 2018 Sep 21.


"How similar is similar enough? A sufficient similarity case study with Ginkgo biloba extract" by Catlin et al.; Food and Chemical Toxicology 118 (2018) 328-339.

Heinrich M.

Food Chem Toxicol. 2018 Nov;121:252-253. doi: 10.1016/j.fct.2018.09.006. Epub 2018 Sep 7. No abstract available.


Recruiting young pre-symptomatic children for a clinical trial in type 1 diabetes: Insights from the Fr1da insulin intervention study.

Kick K, Assfalg R, Aydin S, Bechtold-Dalla Pozza S, Böcker D, Braig S, Bunk M, Dunstheimer D, Durmashkina A, Ermer U, Gavazzeni A, Gerstl EM, Heinrich M, Herbst M, Kriesen Y, Kuhnle-Krahl U, Müller H, Nellen-Hellmuth N, Ockert C, Ramminger C, Sindichakis M, Tretter S, Warncke K, Achenbach P, Ziegler AG, Hoffmann VS.

Contemp Clin Trials Commun. 2018 Aug 15;11:170-173. doi: 10.1016/j.conctc.2018.08.004. eCollection 2018 Sep.


Medicinal benefits of Nigella sativa in bronchial asthma: A literature review.

Koshak A, Koshak E, Heinrich M.

Saudi Pharm J. 2017 Dec;25(8):1130-1136. doi: 10.1016/j.jsps.2017.07.002. Epub 2017 Jul 11. Review.


Total Synthesis of Putative Chagosensine.

Heinrich M, Murphy JJ, Ilg MK, Letort A, Flasz J, Philipps P, Fürstner A.

Angew Chem Int Ed Engl. 2018 Oct 8;57(41):13575-13581. doi: 10.1002/anie.201808937. Epub 2018 Sep 17.


Colistin susceptibility test evaluation of multiple-resistance-level Pseudomonas aeruginosa isolates generated in a morbidostat device.

Javed M, Ueltzhoeffer V, Heinrich M, Siegrist HJ, Wildermuth R, Lorenz FR, Neher RA, Willmann M.

J Antimicrob Chemother. 2018 Dec 1;73(12):3368-3374. doi: 10.1093/jac/dky337.


Translational insights into gastrointestinal stromal tumor and current clinical advances.

Hemming ML, Heinrich MC, Bauer S, George S.

Ann Oncol. 2018 Oct 1;29(10):2037-2045. doi: 10.1093/annonc/mdy309.


Fasting hypoglycemia is associated with disease progression in presymptomatic early stage type 1 diabetes.

Heinrich M, Maison N, Achenbach P, Assfalg R, Braig S, Böcker D, Dunstheimer D, Ermer U, Gavazzeni A, Gerstl EM, Hummel S, Kick K, Müller H, Nellen-Hellmuth N, Ockert C, Sindichakis M, Tretter S, Warncke K, Ziegler AG, Beyerlein A; Fr1da-Study group.

Pediatr Diabetes. 2018 Nov;19(7):1238-1242. doi: 10.1111/pedi.12739. Epub 2018 Sep 3.


[Dementia in Adults with Down Syndrome: A Frequent Reason for Admission to Psychiatry].

Kruse B, Heinrich M, Diefenbacher A, Kaiser H, Sappok T.

Fortschr Neurol Psychiatr. 2018 Jul;86(7):402-409. doi: 10.1055/s-0043-124592. Epub 2018 Jul 20. German.


Model-Based Sparse-to-Dense Image Registration for Realtime Respiratory Motion Estimation in Image-Guided Interventions.

Ha IY, Wilms M, Handels H, Heinrich MP.

IEEE Trans Biomed Eng. 2019 Feb;66(2):302-310. doi: 10.1109/TBME.2018.2837387. Epub 2018 May 16.


Efficacy of Cyberbullying Prevention on Somatic Symptoms-Randomized Controlled Trial Applying a Reasoned Action Approach.

Zagorscak P, Schultze-Krumbholz A, Heinrich M, Wölfer R, Scheithauer H.

J Res Adolesc. 2018 Jul 4. doi: 10.1111/jora.12429. [Epub ahead of print]


Structural and clinical consequences of activation loop mutations in class III receptor tyrosine kinases.

Klug LR, Kent JD, Heinrich MC.

Pharmacol Ther. 2018 Nov;191:123-134. doi: 10.1016/j.pharmthera.2018.06.016. Epub 2018 Jun 30. Review.


Quality control of goji (fruits of Lycium barbarum L. and L. chinense Mill.): A value chain analysis perspective.

Yao R, Heinrich M, Wang Z, Weckerle CS.

J Ethnopharmacol. 2018 Oct 5;224:349-358. doi: 10.1016/j.jep.2018.06.010. Epub 2018 Jun 14.


The German Adaptation of the Therapist Beliefs about Exposure Scale: a Validation Study among Licensed Cognitive Behavioural Therapists in Germany.

Schumacher S, Schopka NM, Heinrich M, Knaevelsrud C.

Behav Cogn Psychother. 2019 Mar;47(2):164-180. doi: 10.1017/S1352465818000371. Epub 2018 Jun 13.


Spatio-temporal analysis of glass volume processing using ultrashort laser pulses.

Bergner K, Seyfarth B, Lammers KA, Ullsperger T, Döring S, Heinrich M, Kumkar M, Flamm D, Tünnermann A, Nolte S.

Appl Opt. 2018 Jun 1;57(16):4618-4632. doi: 10.1364/AO.57.004618.


PSCA expression is associated with favorable tumor features and reduced PSA recurrence in operated prostate cancer.

Heinrich MC, Göbel C, Kluth M, Bernreuther C, Sauer C, Schroeder C, Möller-Koop C, Hube-Magg C, Lebok P, Burandt E, Sauter G, Simon R, Huland H, Graefen M, Heinzer H, Schlomm T, Heumann A.

BMC Cancer. 2018 May 31;18(1):612. doi: 10.1186/s12885-018-4547-7.


TernaryNet: faster deep model inference without GPUs for medical 3D segmentation using sparse and binary convolutions.

Heinrich MP, Blendowski M, Oktay O.

Int J Comput Assist Radiol Surg. 2018 Sep;13(9):1311-1320. doi: 10.1007/s11548-018-1797-4. Epub 2018 May 30.


GIFTed Demons: deformable image registration with local structure-preserving regularization using supervoxels for liver applications.

Papież BW, Franklin JM, Heinrich MP, Gleeson FV, Brady M, Schnabel JA.

J Med Imaging (Bellingham). 2018 Apr;5(2):024001. doi: 10.1117/1.JMI.5.2.024001. Epub 2018 Apr 4.


Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever.

Boisen ML, Hartnett JN, Shaffer JG, Goba A, Momoh M, Sandi JD, Fullah M, Nelson DKS, Bush DJ, Rowland MM, Heinrich ML, Koval AP, Cross RW, Barnes KG, Lachenauer AE, Lin AE, Nekoui M, Kotliar D, Winnicki SM, Siddle KJ, Gbakie M, Fonnie M, Koroma VJ, Kanneh L, Kulakosky PC, Hastie KM, Wilson RB, Andersen KG, Folarin OO, Happi CT, Sabeti PC, Geisbert TW, Saphire EO, Khan SH, Grant DS, Schieffelin JS, Branco LM, Garry RF.

Sci Rep. 2018 Apr 12;8(1):5939. doi: 10.1038/s41598-018-24246-w.

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