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Items: 1 to 50 of 52

1.

The transcription factor GATA4 promotes myocardial regeneration in neonatal mice.

Malek Mohammadi M, Kattih B, Grund A, Froese N, Korf-Klingebiel M, Gigina A, Schrameck U, Rudat C, Liang Q, Kispert A, Wollert KC, Bauersachs J, Heineke J.

EMBO Mol Med. 2019 Jun;11(6). pii: e10678. doi: 10.15252/emmm.201910678. No abstract available.

2.

Hepatic Endothelial Notch Activation Protects against Liver Metastasis by Regulating Endothelial-Tumor Cell Adhesion Independent of Angiocrine Signaling.

Wohlfeil SA, Häfele V, Dietsch B, Schledzewski K, Winkler M, Zierow J, Leibing T, Mohammadi MM, Heineke J, Sticht C, Olsavszky V, Koch PS, Géraud C, Goerdt S.

Cancer Res. 2019 Feb 1;79(3):598-610. doi: 10.1158/0008-5472.CAN-18-1752. Epub 2018 Dec 10.

PMID:
30530502
3.

Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease.

Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW.

Mol Metab. 2019 Feb;20:102-114. doi: 10.1016/j.molmet.2018.11.002. Epub 2018 Nov 15.

4.

Corrigendum to "Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice" Journal of Molecular and Cellular Cardiology 122 (2018) 114-124.

Froese N, Wang H, Zwadlo C, Wang Y, Grund A, Gigina A, Hofmann M, Kilian K, Scharf G, Korf-Klingebiel M, Melchert A, Signorini MER, Halloin C, Zweigerdt R, Martin U, Gruh I, Wollert KC, Geffers R, Bauersachs J, Heineke J.

J Mol Cell Cardiol. 2018 Dec;125:205. doi: 10.1016/j.yjmcc.2018.11.003. Epub 2018 Nov 7. No abstract available.

PMID:
30414408
5.

Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice.

Froese N, Wang H, Zwadlo C, Wang Y, Grund A, Gigina A, Hofmann M, Kilian K, Scharf G, Korf-Klingebiel M, Melchert A, Signorini MER, Halloin C, Zweigerdt R, Martin U, Gruh I, Wollert KC, Geffers R, Bauersachs J, Heineke J.

J Mol Cell Cardiol. 2018 Sep;122:114-124. doi: 10.1016/j.yjmcc.2018.08.011. Epub 2018 Aug 14. Erratum in: J Mol Cell Cardiol. 2018 Dec;125:205.

PMID:
30118791
6.

Impact of Altered Mineral Metabolism on Pathological Cardiac Remodeling in Elevated Fibroblast Growth Factor 23.

Leifheit-Nestler M, Richter B, Basaran M, Nespor J, Vogt I, Alesutan I, Voelkl J, Lang F, Heineke J, Krick S, Haffner D.

Front Endocrinol (Lausanne). 2018 Jun 21;9:333. doi: 10.3389/fendo.2018.00333. eCollection 2018.

7.

A gene therapeutic approach to inhibit calcium and integrin binding protein 1 ameliorates maladaptive remodelling in pressure overload.

Grund A, Szaroszyk M, Döppner JK, Malek Mohammadi M, Kattih B, Korf-Klingebiel M, Gigina A, Scherr M, Kensah G, Jara-Avaca M, Gruh I, Martin U, Wollert KC, Gohla A, Katus HA, Müller OJ, Bauersachs J, Heineke J.

Cardiovasc Res. 2019 Jan 1;115(1):71-82. doi: 10.1093/cvr/cvy154.

PMID:
29931050
8.

Fibroblast growth factor 23 is induced by an activated renin-angiotensin-aldosterone system in cardiac myocytes and promotes the pro-fibrotic crosstalk between cardiac myocytes and fibroblasts.

Leifheit-Nestler M, Kirchhoff F, Nespor J, Richter B, Soetje B, Klintschar M, Heineke J, Haffner D.

Nephrol Dial Transplant. 2018 Oct 1;33(10):1722-1734. doi: 10.1093/ndt/gfy006.

PMID:
29425341
9.

Localization of transcripts, translation, and degradation for spatiotemporal sarcomere maintenance.

Lewis YE, Moskovitz A, Mutlak M, Heineke J, Caspi LH, Kehat I.

J Mol Cell Cardiol. 2018 Mar;116:16-28. doi: 10.1016/j.yjmcc.2018.01.012. Epub 2018 Jan 31.

PMID:
29371135
10.

My Cup Runneth Over.

Kittelson S, Heineke J, Carlos WG.

J Palliat Med. 2018 Mar;21(3):279. doi: 10.1089/jpm.2017.0557. Epub 2017 Nov 7. No abstract available.

PMID:
29112464
11.

Insulin supplementation attenuates cancer-induced cardiomyopathy and slows tumor disease progression.

Thackeray JT, Pietzsch S, Stapel B, Ricke-Hoch M, Lee CW, Bankstahl JP, Scherr M, Heineke J, Scharf G, Haghikia A, Bengel FM, Hilfiker-Kleiner D.

JCI Insight. 2017 May 18;2(10). pii: 93098. doi: 10.1172/jci.insight.93098. eCollection 2017 May 18.

12.

The transcription factor GATA4 promotes myocardial regeneration in neonatal mice.

Malek Mohammadi M, Kattih B, Grund A, Froese N, Korf-Klingebiel M, Gigina A, Schrameck U, Rudat C, Liang Q, Kispert A, Wollert KC, Bauersachs J, Heineke J.

EMBO Mol Med. 2017 Feb;9(2):265-279. doi: 10.15252/emmm.201606602. Erratum in: EMBO Mol Med. 2019 Jun;11(6):.

13.

Cardiotoxic Antiemetics Metoclopramide and Domperidone Block Cardiac Voltage-Gated Na+ Channels.

Stoetzer C, Voelker M, Doll T, Heineke J, Wegner F, Leffler A.

Anesth Analg. 2017 Jan;124(1):52-60.

PMID:
27861438
14.

C1q-TNF-Related Protein-9 Promotes Cardiac Hypertrophy and Failure.

Appari M, Breitbart A, Brandes F, Szaroszyk M, Froese N, Korf-Klingebiel M, Mohammadi MM, Grund A, Scharf GM, Wang H, Zwadlo C, Fraccarollo D, Schrameck U, Nemer M, Wong GW, Katus HA, Wollert KC, Müller OJ, Bauersachs J, Heineke J.

Circ Res. 2017 Jan 6;120(1):66-77. doi: 10.1161/CIRCRESAHA.116.309398. Epub 2016 Nov 7.

PMID:
27821723
15.

MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease.

Hartmann D, Fiedler J, Sonnenschein K, Just A, Pfanne A, Zimmer K, Remke J, Foinquinos A, Butzlaff M, Schimmel K, Maegdefessel L, Hilfiker-Kleiner D, Lachmann N, Schober A, Froese N, Heineke J, Bauersachs J, Batkai S, Thum T.

Circulation. 2016 Dec 13;134(24):1973-1990. Epub 2016 Oct 25.

PMID:
27780851
16.

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

Barallobre-Barreiro J, Gupta SK, Zoccarato A, Kitazume-Taneike R, Fava M, Yin X, Werner T, Hirt MN, Zampetaki A, Viviano A, Chong M, Bern M, Kourliouros A, Domenech N, Willeit P, Shah AM, Jahangiri M, Schaefer L, Fischer JW, Iozzo RV, Viner R, Thum T, Heineke J, Kichler A, Otsu K, Mayr M.

Circulation. 2016 Sep 13;134(11):817-32. doi: 10.1161/CIRCULATIONAHA.115.016423. Epub 2016 Aug 24.

17.

Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure.

Haddad S, Wang Y, Galy B, Korf-Klingebiel M, Hirsch V, Baru AM, Rostami F, Reboll MR, Heineke J, Flögel U, Groos S, Renner A, Toischer K, Zimmermann F, Engeli S, Jordan J, Bauersachs J, Hentze MW, Wollert KC, Kempf T.

Eur Heart J. 2017 Feb 1;38(5):362-372. doi: 10.1093/eurheartj/ehw333.

PMID:
27545647
18.

Differential inhibition of cardiac and neuronal Na(+) channels by the selective serotonin-norepinephrine reuptake inhibitors duloxetine and venlafaxine.

Stoetzer C, Papenberg B, Doll T, Völker M, Heineke J, Stoetzer M, Wegner F, Leffler A.

Eur J Pharmacol. 2016 Jul 15;783:1-10. doi: 10.1016/j.ejphar.2016.04.051. Epub 2016 Apr 27.

PMID:
27130441
19.

Reductions in Diagnostic Imaging With High Deductible Health Plans.

Zheng S, Ren ZJ, Heineke J, Geissler KH.

Med Care. 2016 Feb;54(2):110-7. doi: 10.1097/MLR.0000000000000472.

PMID:
26761726
20.

Blood-based microRNA signatures differentiate various forms of cardiac hypertrophy.

Derda AA, Thum S, Lorenzen JM, Bavendiek U, Heineke J, Keyser B, Stuhrmann M, Givens RC, Kennel PJ, Schulze PC, Widder JD, Bauersachs J, Thum T.

Int J Cardiol. 2015 Oct 1;196:115-22. doi: 10.1016/j.ijcard.2015.05.185. Epub 2015 Jun 5.

21.

Antiandrogenic therapy with finasteride attenuates cardiac hypertrophy and left ventricular dysfunction.

Zwadlo C, Schmidtmann E, Szaroszyk M, Kattih B, Froese N, Hinz H, Schmitto JD, Widder J, Batkai S, Bähre H, Kaever V, Thum T, Bauersachs J, Heineke J.

Circulation. 2015 Mar 24;131(12):1071-81. doi: 10.1161/CIRCULATIONAHA.114.012066. Epub 2015 Jan 28.

PMID:
25632043
22.

Exercise makes the difference: deconstructing physiological hypertrophy in swine.

Grund A, Heineke J.

J Mol Cell Cardiol. 2015 Feb;79:89-91. doi: 10.1016/j.yjmcc.2014.11.001. Epub 2014 Nov 13. No abstract available.

PMID:
25450616
23.

Building the case for quality improvement in the health care industry: a focus on goals and training.

Field JM, Heineke J, Langabeer JR, DelliFraine JL.

Qual Manag Health Care. 2014 Jul-Sep;23(3):138-54. doi: 10.1097/QMH.0000000000000036.

PMID:
24978163
24.

MicroRNA-24 antagonism prevents renal ischemia reperfusion injury.

Lorenzen JM, Kaucsar T, Schauerte C, Schmitt R, Rong S, Hübner A, Scherf K, Fiedler J, Martino F, Kumarswamy R, Kölling M, Sörensen I, Hinz H, Heineke J, van Rooij E, Haller H, Thum T.

J Am Soc Nephrol. 2014 Dec;25(12):2717-29. doi: 10.1681/ASN.2013121329. Epub 2014 May 22.

25.

Highly specific detection of myostatin prodomain by an immunoradiometric sandwich assay in serum of healthy individuals and patients.

Breitbart A, Scharf GM, Duncker D, Widera C, Gottlieb J, Vogel A, Schmidt S, Brandes G, Heuft HG, Lichtinghagen R, Kempf T, Wollert KC, Bauersachs J, Heineke J.

PLoS One. 2013 Nov 15;8(11):e80454. doi: 10.1371/journal.pone.0080454. eCollection 2013.

26.

Screening for novel calcium-binding proteins that regulate cardiac hypertrophy: CIB1 as an example.

Heineke J.

Methods Mol Biol. 2013;963:279-301. doi: 10.1007/978-1-62703-230-8_17.

PMID:
23296617
27.

The accountable health care act of Massachusetts: mixed results for an experiment in universal health care coverage.

Norbash A, Hindson D, Heineke J.

J Am Coll Radiol. 2012 Oct;9(10):734-9. doi: 10.1016/j.jacr.2012.06.016.

PMID:
23025869
28.

Finding good biomarkers for sarcopenia.

Scharf G, Heineke J.

J Cachexia Sarcopenia Muscle. 2012 Sep;3(3):145-8. doi: 10.1007/s13539-012-0081-7. Epub 2012 Aug 2.

29.

Wag the dog: how endothelial cells regulate cardiomyocyte growth.

Heineke J.

Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):545-7. doi: 10.1161/ATVBAHA.111.242784. No abstract available.

PMID:
22345589
30.

Cardiomyocyte calcineurin signaling in subcellular domains: from the sarcolemma to the nucleus and beyond.

Heineke J, Ritter O.

J Mol Cell Cardiol. 2012 Jan;52(1):62-73. doi: 10.1016/j.yjmcc.2011.10.018. Epub 2011 Oct 29. Review.

PMID:
22064325
31.

Bringing responsibility for small area variations in hospitalization rates back to the hospital: the propensity to hospitalize index and a test of the Roemer's Law.

Shwartz M, Peköz EA, Labonte A, Heineke J, Restuccia JD.

Med Care. 2011 Dec;49(12):1062-7. doi: 10.1097/MLR.0b013e3182353907.

PMID:
22002646
32.

MicroRNA-24 regulates vascularity after myocardial infarction.

Fiedler J, Jazbutyte V, Kirchmaier BC, Gupta SK, Lorenzen J, Hartmann D, Galuppo P, Kneitz S, Pena JT, Sohn-Lee C, Loyer X, Soutschek J, Brand T, Tuschl T, Heineke J, Martin U, Schulte-Merker S, Ertl G, Engelhardt S, Bauersachs J, Thum T.

Circulation. 2011 Aug 9;124(6):720-30. doi: 10.1161/CIRCULATIONAHA.111.039008. Epub 2011 Jul 25.

PMID:
21788589
33.

Syndecan-4 signalling inhibits apoptosis and controls NFAT activity during myocardial damage and remodelling.

Echtermeyer F, Harendza T, Hubrich S, Lorenz A, Herzog C, Mueller M, Schmitz M, Grund A, Larmann J, Stypmann J, Schieffer B, Lichtinghagen R, Hilfiker-Kleiner D, Wollert KC, Heineke J, Theilmeier G.

Cardiovasc Res. 2011 Oct 1;92(1):123-31. doi: 10.1093/cvr/cvr149. Epub 2011 Jun 1.

PMID:
21632883
34.

Myostatin from the heart: local and systemic actions in cardiac failure and muscle wasting.

Breitbart A, Auger-Messier M, Molkentin JD, Heineke J.

Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H1973-82. doi: 10.1152/ajpheart.00200.2011. Epub 2011 Mar 18. Review.

35.

Conditional transgenic expression of fibroblast growth factor 9 in the adult mouse heart reduces heart failure mortality after myocardial infarction.

Korf-Klingebiel M, Kempf T, Schlüter KD, Willenbockel C, Brod T, Heineke J, Schmidt VJ, Jantzen F, Brandes RP, Sugden PH, Drexler H, Molkentin JD, Wollert KC.

Circulation. 2011 Feb 8;123(5):504-14. doi: 10.1161/CIRCULATIONAHA.110.989665. Epub 2011 Jan 24.

PMID:
21262993
36.

GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling.

Froese N, Kattih B, Breitbart A, Grund A, Geffers R, Molkentin JD, Kispert A, Wollert KC, Drexler H, Heineke J.

J Biol Chem. 2011 Feb 18;286(7):5680-90. doi: 10.1074/jbc.M110.176925. Epub 2010 Dec 2.

37.

CIB1 is a regulator of pathological cardiac hypertrophy.

Heineke J, Auger-Messier M, Correll RN, Xu J, Benard MJ, Yuan W, Drexler H, Parise LV, Molkentin JD.

Nat Med. 2010 Aug;16(8):872-9. doi: 10.1038/nm.2181. Epub 2010 Jul 18.

38.

Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure.

Heineke J, Auger-Messier M, Xu J, Sargent M, York A, Welle S, Molkentin JD.

Circulation. 2010 Jan 26;121(3):419-25. doi: 10.1161/CIRCULATIONAHA.109.882068. Epub 2010 Jan 11.

39.

Calcineurin protects the heart in a murine model of dilated cardiomyopathy.

Heineke J, Wollert KC, Osinska H, Sargent MA, York AJ, Robbins J, Molkentin JD.

J Mol Cell Cardiol. 2010 Jun;48(6):1080-7. doi: 10.1016/j.yjmcc.2009.10.012. Epub 2009 Oct 22.

40.

MLP: a stress sensor goes nuclear.

Gunkel S, Heineke J, Hilfiker-Kleiner D, Knöll R.

J Mol Cell Cardiol. 2009 Oct;47(4):423-5. doi: 10.1016/j.yjmcc.2009.07.012. Epub 2009 Jul 17. No abstract available. Erratum in: J Mol Cell Cardiol. 2010 Apr;48(4):807.

PMID:
19616554
41.

Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart.

Heineke J, Auger-Messier M, Xu J, Oka T, Sargent MA, York A, Klevitsky R, Vaikunth S, Duncan SA, Aronow BJ, Robbins J, Crombleholme TM, Molkentin JD.

J Clin Invest. 2007 Nov;117(11):3198-210. Erratum in: J Clin Invest. 2008 Jan;118(1):387. Cromblehol, Timothy M [corrected to Crombleholme, Timothy M].

42.

Reduced delayed rectifier K+ current, altered electrophysiology, and increased ventricular vulnerability in MLP-deficient mice.

Gardiwal A, Klein G, Kraemer K, Durgac T, Koenig T, Niehaus M, Heineke J, Mohammadi B, Krampfl K, Schaefer A, Wollert KC, Korte T.

J Card Fail. 2007 Oct;13(8):687-93.

PMID:
17923363
43.

Toward an effective strategy for the diffusion and use of clinical information systems.

Davidson SM, Heineke J.

J Am Med Inform Assoc. 2007 May-Jun;14(3):361-7. Epub 2007 Feb 28.

44.

Regulation of cardiac hypertrophy by intracellular signalling pathways.

Heineke J, Molkentin JD.

Nat Rev Mol Cell Biol. 2006 Aug;7(8):589-600. Review.

PMID:
16936699
45.

The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury.

Kempf T, Eden M, Strelau J, Naguib M, Willenbockel C, Tongers J, Heineke J, Kotlarz D, Xu J, Molkentin JD, Niessen HW, Drexler H, Wollert KC.

Circ Res. 2006 Feb 17;98(3):351-60. Epub 2006 Jan 5.

PMID:
16397141
46.

Attenuation of cardiac remodeling after myocardial infarction by muscle LIM protein-calcineurin signaling at the sarcomeric Z-disc.

Heineke J, Ruetten H, Willenbockel C, Gross SC, Naguib M, Schaefer A, Kempf T, Hilfiker-Kleiner D, Caroni P, Kraft T, Kaiser RA, Molkentin JD, Drexler H, Wollert KC.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1655-60. Epub 2005 Jan 21.

47.

Heme oxygenase-1 inhibition of MAP kinases, calcineurin/NFAT signaling, and hypertrophy in cardiac myocytes.

Tongers J, Fiedler B, König D, Kempf T, Klein G, Heineke J, Kraft T, Gambaryan S, Lohmann SM, Drexler H, Wollert KC.

Cardiovasc Res. 2004 Aug 15;63(3):545-52.

PMID:
15276480
48.

Downregulation of cytoskeletal muscle LIM protein by nitric oxide: impact on cardiac myocyte hypertrophy.

Heineke J, Kempf T, Kraft T, Hilfiker A, Morawietz H, Scheubel RJ, Caroni P, Lohmann SM, Drexler H, Wollert KC.

Circulation. 2003 Mar 18;107(10):1424-32.

PMID:
12642365
49.

Does more "appropriateness" explain higher rates of cardiac procedures among patients hospitalized with coronary heart disease?

Restuccia JD, Shwartz M, Kreger BE, Payne SM, Ash AS, Iezzoni LI, Heineke J, Selker HP, Gomes T, Labonte A, Butterly JR.

Med Care. 2002 Jun;40(6):500-9.

PMID:
12021676
50.

Gene transfer of cGMP-dependent protein kinase I enhances the antihypertrophic effects of nitric oxide in cardiomyocytes.

Wollert KC, Fiedler B, Gambaryan S, Smolenski A, Heineke J, Butt E, Trautwein C, Lohmann SM, Drexler H.

Hypertension. 2002 Jan;39(1):87-92.

PMID:
11799084

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