Format
Sort by
Items per page

Send to

Choose Destination

Best matches for Heinegård D[au]:

Search results

Items: 1 to 50 of 331

1.

Chondrocytes Derived From Mesenchymal Stromal Cells and Induced Pluripotent Cells of Patients With Familial Osteochondritis Dissecans Exhibit an Endoplasmic Reticulum Stress Response and Defective Matrix Assembly.

Xu M, Stattin EL, Shaw G, Heinegård D, Sullivan G, Wilmut I, Colman A, Önnerfjord P, Khabut A, Aspberg A, Dockery P, Hardingham T, Murphy M, Barry F.

Stem Cells Transl Med. 2016 Sep;5(9):1171-81. doi: 10.5966/sctm.2015-0384. Epub 2016 Jul 7.

2.

The α2β1 binding domain of chondroadherin inhibits breast cancer-induced bone metastases and impairs primary tumour growth: a preclinical study.

Rucci N, Capulli M, Olstad OK, Önnerfjord P, Tillgren V, Gautvik KM, Heinegård D, Teti A.

Cancer Lett. 2015 Mar 1;358(1):67-75. doi: 10.1016/j.canlet.2014.12.032. Epub 2014 Dec 18.

PMID:
25529009
3.

Quantitative proteomics at different depths in human articular cartilage reveals unique patterns of protein distribution.

Müller C, Khabut A, Dudhia J, Reinholt FP, Aspberg A, Heinegård D, Önnerfjord P.

Matrix Biol. 2014 Nov;40:34-45. doi: 10.1016/j.matbio.2014.08.013. Epub 2014 Sep 1.

4.

Novel cartilage oligomeric matrix protein (COMP) neoepitopes identified in synovial fluids from patients with joint diseases using affinity chromatography and mass spectrometry.

Åhrman E, Lorenzo P, Holmgren K, Grodzinsky AJ, Dahlberg LE, Saxne T, Heinegård D, Önnerfjord P.

J Biol Chem. 2014 Jul 25;289(30):20908-16.

5.

Nanomechanical phenotype of chondroadherin-null murine articular cartilage.

Batista MA, Nia HT, Önnerfjord P, Cox KA, Ortiz C, Grodzinsky AJ, Heinegård D, Han L.

Matrix Biol. 2014 Sep;38:84-90. doi: 10.1016/j.matbio.2014.05.008. Epub 2014 Jun 2.

6.

Link N is cleaved by human annulus fibrosus cells generating a fragment with retained biological activity.

Gawri R, Ouellet J, Önnerfjord P, Alkhatib B, Steffen T, Heinegård D, Roughley P, Antoniou J, Mwale F, Haglund L.

J Orthop Res. 2014 Sep;32(9):1189-97. doi: 10.1002/jor.22653. Epub 2014 May 23.

7.

The C-terminal domain of chondroadherin: a new regulator of osteoclast motility counteracting bone loss.

Capulli M, Olstad OK, Onnerfjord P, Tillgren V, Muraca M, Gautvik KM, Heinegård D, Rucci N, Teti A.

J Bone Miner Res. 2014 Aug;29(8):1833-46. doi: 10.1002/jbmr.2206.

8.

Proteomic analysis of tendon extracellular matrix reveals disease stage-specific fragmentation and differential cleavage of COMP (cartilage oligomeric matrix protein).

Dakin SG, Smith RK, Heinegård D, Önnerfjord P, Khabut A, Dudhia J.

J Biol Chem. 2014 Feb 21;289(8):4919-27. doi: 10.1074/jbc.M113.511972. Epub 2014 Jan 7.

9.

Cartilage oligomeric matrix protein-induced complement activation in systemic sclerosis.

Otteby KE, Holmquist E, Saxne T, Heinegård D, Hesselstrand R, Blom AM.

Arthritis Res Ther. 2013;15(6):R215.

10.

Advances in the understanding of tendinopathies: a report on the Second Havemeyer Workshop on equine tendon disease.

Smith R, McIlwraith W, Schweitzer R, Kadler K, Cook J, Caterson B, Dakin S, Heinegård D, Screen H, Stover S, Crevier-Denoix N, Clegg P, Collins M, Little C, Frisbie D, Kjaer M, van Weeren R, Werpy N, Denoix JM, Carr A, Goldberg A, Bramlage L, Smith M, Nixon A.

Equine Vet J. 2014 Jan;46(1):4-9. doi: 10.1111/evj.12128. No abstract available.

PMID:
24329581
11.

COMP-C3b complexes in rheumatoid arthritis with severe extraarticular manifestations.

Happonen KE, Saxne T, Jacobsson L, Sturfelt G, Rönnelid J, Mollnes TE, Heinegård D, Turesson C, Blom AM.

J Rheumatol. 2013 Dec;40(12):2001-5. doi: 10.3899/jrheum.130613. Epub 2013 Nov 1.

PMID:
24187101
12.

Early increase in serum-COMP is associated with joint damage progression over the first five years in patients with rheumatoid arthritis.

Andersson ML, Svensson B, Petersson IF, Hafström I, Albertsson K, Forslind K, Heinegård D, Saxne T.

BMC Musculoskelet Disord. 2013 Aug 2;14:229. doi: 10.1186/1471-2474-14-229.

13.

The skeletal phenotype of chondroadherin deficient mice.

Hessle L, Stordalen GA, Wenglén C, Petzold C, Tanner E, Brorson SH, Baekkevold ES, Önnerfjord P, Reinholt FP, Heinegård D.

PLoS One. 2013 Jun 3;8(6):e63080. doi: 10.1371/journal.pone.0063080. Print 2014. Erratum in: PLoS One. 2013;8(7). doi:10.1371/annotation/cb7d7b4c-624f-46e6-957e-13b355ca8e02.

14.

Chondroadherin fragmentation mediated by the protease HTRA1 distinguishes human intervertebral disc degeneration from normal aging.

Akhatib B, Onnerfjord P, Gawri R, Ouellet J, Jarzem P, Heinegård D, Mort J, Roughley P, Haglund L.

J Biol Chem. 2013 Jun 28;288(26):19280-7. doi: 10.1074/jbc.M112.443010. Epub 2013 May 14.

15.

The C-type lectin of the aggrecan G3 domain activates complement.

Melin Fürst C, Mörgelin M, Vadstrup K, Heinegård D, Aspberg A, Blom AM.

PLoS One. 2013 Apr 15;8(4):e61407. doi: 10.1371/journal.pone.0061407. Print 2013.

16.

Proline/arginine-rich end leucine-rich repeat protein N-terminus is a novel osteoclast antagonist that counteracts bone loss.

Rucci N, Capulli M, Ventura L, Angelucci A, Peruzzi B, Tillgren V, Muraca M, Heinegård D, Teti A.

J Bone Miner Res. 2013 Sep;28(9):1912-24. doi: 10.1002/jbmr.1951.

17.

Enhanced deposition of cartilage oligomeric matrix protein is a common feature in fibrotic skin pathologies.

Agarwal P, Schulz JN, Blumbach K, Andreasson K, Heinegård D, Paulsson M, Mauch C, Eming SA, Eckes B, Krieg T.

Matrix Biol. 2013 Aug 8;32(6):325-31. doi: 10.1016/j.matbio.2013.02.010. Epub 2013 Mar 15.

PMID:
23507196
18.

The C-terminal peptide of chondroadherin modulates cellular activity by selectively binding to heparan sulfate chains.

Haglund L, Tillgren V, Önnerfjord P, Heinegård D.

J Biol Chem. 2013 Jan 11;288(2):995-1008. doi: 10.1074/jbc.M112.430512. Epub 2012 Nov 21.

19.

Immunolocalization of collagens (I and III) and cartilage oligomeric matrix protein in the normal and injured equine superficial digital flexor tendon.

Södersten F, Hultenby K, Heinegård D, Johnston C, Ekman S.

Connect Tissue Res. 2013;54(1):62-9. doi: 10.3109/03008207.2012.734879. Epub 2012 Dec 3.

20.

Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases.

Happonen KE, Heinegård D, Saxne T, Blom AM.

Immunobiology. 2012 Nov;217(11):1088-96. doi: 10.1016/j.imbio.2012.07.013. Review.

PMID:
22964234
21.

Collagen XII and XIV, new partners of cartilage oligomeric matrix protein in the skin extracellular matrix suprastructure.

Agarwal P, Zwolanek D, Keene DR, Schulz JN, Blumbach K, Heinegård D, Zaucke F, Paulsson M, Krieg T, Koch M, Eckes B.

J Biol Chem. 2012 Jun 29;287(27):22549-59. doi: 10.1074/jbc.M111.335935. Epub 2012 May 9.

22.

Quantitative proteomic analysis of eight cartilaginous tissues reveals characteristic differences as well as similarities between subgroups.

Önnerfjord P, Khabut A, Reinholt FP, Svensson O, Heinegård D.

J Biol Chem. 2012 Jun 1;287(23):18913-24. doi: 10.1074/jbc.M111.298968. Epub 2012 Apr 9.

23.

Extracellular matrix alterations and acute inflammation; developing in parallel during early induction of pulmonary fibrosis.

Rydell-Törmänen K, Andréasson K, Hesselstrand R, Risteli J, Heinegård D, Saxne T, Westergren-Thorsson G.

Lab Invest. 2012 Jun;92(6):917-25. doi: 10.1038/labinvest.2012.57. Epub 2012 Apr 2.

24.

Is cartilage sGAG content related to early changes in cartilage disease? Implications for interpretation of dGEMRIC.

Stubendorff JJ, Lammentausta E, Struglics A, Lindberg L, Heinegård D, Dahlberg LE.

Osteoarthritis Cartilage. 2012 May;20(5):396-404. doi: 10.1016/j.joca.2012.01.015. Epub 2012 Feb 11.

25.

PRELP protein inhibits the formation of the complement membrane attack complex.

Happonen KE, Fürst CM, Saxne T, Heinegård D, Blom AM.

J Biol Chem. 2012 Mar 9;287(11):8092-100. doi: 10.1074/jbc.M111.291476. Epub 2012 Jan 20. Erratum in: J Biol Chem. 2012 Jun 1;287(23):19338.

26.

Diseases of the musculosketelal system. Preface.

Heinegård D, Smolen JS.

Best Pract Res Clin Rheumatol. 2011 Dec;25(6):749-50. doi: 10.1016/j.berh.2011.11.011. No abstract available.

PMID:
22265257
27.

Serum COMP-C3b complexes in rheumatic diseases and relation to anti-TNF-α treatment.

Happonen KE, Saxne T, Geborek P, Andersson M, Bengtsson AA, Hesselstrand R, Heinegård D, Blom AM.

Arthritis Res Ther. 2012 Jan 20;14(1):R15. doi: 10.1186/ar3694.

29.

Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis.

Kraus VB, Burnett B, Coindreau J, Cottrell S, Eyre D, Gendreau M, Gardiner J, Garnero P, Hardin J, Henrotin Y, Heinegård D, Ko A, Lohmander LS, Matthews G, Menetski J, Moskowitz R, Persiani S, Poole AR, Rousseau JC, Todman M; OARSI FDA Osteoarthritis Biomarkers Working Group.

Osteoarthritis Cartilage. 2011 May;19(5):515-42. doi: 10.1016/j.joca.2010.08.019. Epub 2011 Mar 23.

30.

Degradation of extracellular matrix molecules in interleukin-1α treated bovine nasal cartilage.

Shohani B, Orazizadeh M, Hashemitabar M, Heinegard D.

Iran Biomed J. 2010 Oct;14(4):158-63.

31.

Serglycin inhibits the classical and lectin pathways of complement via its glycosaminoglycan chains: implications for multiple myeloma.

Skliris A, Happonen KE, Terpos E, Labropoulou V, Børset M, Heinegård D, Blom AM, Theocharis AD.

Eur J Immunol. 2011 Feb;41(2):437-49. doi: 10.1002/eji.201040429. Epub 2010 Dec 30.

32.

Identification and characterization of the integrin alpha2beta1 binding motif in chondroadherin mediating cell attachment.

Haglund L, Tillgren V, Addis L, Wenglén C, Recklies A, Heinegård D.

J Biol Chem. 2011 Feb 4;286(5):3925-34. doi: 10.1074/jbc.M110.161141. Epub 2010 Dec 2.

33.

The role of the cartilage matrix in osteoarthritis.

Heinegård D, Saxne T.

Nat Rev Rheumatol. 2011 Jan;7(1):50-6. doi: 10.1038/nrrheum.2010.198. Epub 2010 Nov 30. Review.

PMID:
21119607
34.

Increased cartilage oligomeric matrix protein concentrations in equine digital flexor tendon sheath synovial fluid predicts intrathecal tendon damage.

Smith MR, Wright IM, Minshall GJ, Dudhia J, Verheyen K, Heinegård D, Smith RK.

Vet Surg. 2011 Jan;40(1):54-8. doi: 10.1111/j.1532-950X.2010.00751.x. Epub 2010 Nov 15.

PMID:
21077920
35.

The streptococcal collagen-binding protein CNE specifically interferes with alphaVbeta3-mediated cellular interactions with triple helical collagen.

van Wieringen T, Kalamajski S, Lidén A, Bihan D, Guss B, Heinegård D, Farndale RW, Rubin K.

J Biol Chem. 2010 Nov 12;285(46):35803-13. doi: 10.1074/jbc.M110.146001. Epub 2010 Sep 13.

36.

Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis.

Happonen KE, Saxne T, Aspberg A, Mörgelin M, Heinegård D, Blom AM.

Arthritis Rheum. 2010 Dec;62(12):3574-83. doi: 10.1002/art.27720.

37.

A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans.

Stattin EL, Wiklund F, Lindblom K, Onnerfjord P, Jonsson BA, Tegner Y, Sasaki T, Struglics A, Lohmander S, Dahl N, Heinegård D, Aspberg A.

Am J Hum Genet. 2010 Feb 12;86(2):126-37. doi: 10.1016/j.ajhg.2009.12.018. Epub 2010 Feb 4.

38.

Fell-Muir Lecture: Proteoglycans and more--from molecules to biology.

Heinegård D.

Int J Exp Pathol. 2009 Dec;90(6):575-86. doi: 10.1111/j.1365-2613.2009.00695.x. Review.

39.

The glycosaminoglycan-binding domain of PRELP acts as a cell type-specific NF-kappaB inhibitor that impairs osteoclastogenesis.

Rucci N, Rufo A, Alamanou M, Capulli M, Del Fattore A, Ahrman E, Capece D, Iansante V, Zazzeroni F, Alesse E, Heinegård D, Teti A.

J Cell Biol. 2009 Nov 30;187(5):669-83. doi: 10.1083/jcb.200906014.

40.

Ultrastructural immunolocalization of cartilage oligomeric matrix protein (COMP) in the articular cartilage on the equine third carpal bone in trained and untrained horses.

Skiöldebrand E, Ekman S, Heinegård D, Hultenby K.

Res Vet Sci. 2010 Apr;88(2):251-7. doi: 10.1016/j.rvsc.2009.07.011. Epub 2009 Aug 28.

PMID:
19716571
41.

The tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors.

Tillgren V, Onnerfjord P, Haglund L, Heinegård D.

J Biol Chem. 2009 Oct 16;284(42):28543-53. doi: 10.1074/jbc.M109.047076. Epub 2009 Aug 21.

42.

Glucosamine but not ibuprofen alters cartilage turnover in osteoarthritis patients in response to physical training.

Petersen SG, Saxne T, Heinegard D, Hansen M, Holm L, Koskinen S, Stordal C, Christensen H, Aagaard P, Kjaer M.

Osteoarthritis Cartilage. 2010 Jan;18(1):34-40. doi: 10.1016/j.joca.2009.07.004. Epub 2009 Jul 15.

43.

Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system.

Manderson GA, Martin M, Onnerfjord P, Saxne T, Schmidtchen A, Mollnes TE, Heinegård D, Blom AM.

Mol Immunol. 2009 Oct;46(16):3388-98. doi: 10.1016/j.molimm.2009.07.011. Epub 2009 Aug 11.

PMID:
19674792
44.

Asporin competes with decorin for collagen binding, binds calcium and promotes osteoblast collagen mineralization.

Kalamajski S, Aspberg A, Lindblom K, Heinegård D, Oldberg A.

Biochem J. 2009 Sep 14;423(1):53-9. doi: 10.1042/BJ20090542.

PMID:
19589127
45.

Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix.

Happonen KE, Sjöberg AP, Mörgelin M, Heinegård D, Blom AM.

J Immunol. 2009 Feb 1;182(3):1518-25.

46.

Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation.

Sjöberg AP, Manderson GA, Mörgelin M, Day AJ, Heinegård D, Blom AM.

Mol Immunol. 2009 Feb;46(5):830-9. doi: 10.1016/j.molimm.2008.09.018. Epub 2008 Oct 29.

47.

Purification, crystallization and preliminary X-ray diffraction analysis of human chondroadherin.

Pramhed A, Addis L, Tillgren V, Wenglén C, Heinegård D, Logan DT.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jun 1;64(Pt 6):516-9. doi: 10.1107/S1744309108012141. Epub 2008 May 23.

48.

Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis.

Surmann-Schmitt C, Dietz U, Kireva T, Adam N, Park J, Tagariello A, Onnerfjord P, Heinegård D, Schlötzer-Schrehardt U, Deutzmann R, von der Mark K, Stock M.

J Biol Chem. 2008 Mar 14;283(11):7082-93. Epub 2007 Dec 21.

49.

COMP: a candidate molecule in the pathogenesis of systemic sclerosis with a potential as a disease marker.

Hesselstrand R, Kassner A, Heinegård D, Saxne T.

Ann Rheum Dis. 2008 Sep;67(9):1242-8. Epub 2007 Dec 7.

PMID:
18065498
50.

Altered osteoclast development and function in osteopontin deficient mice.

Franzén A, Hultenby K, Reinholt FP, Onnerfjord P, Heinegård D.

J Orthop Res. 2008 May;26(5):721-8.

Supplemental Content

Loading ...
Support Center