Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 71

1.

Cell Replacement Therapy Improves Pathological Hallmarks in a Mouse Model of Leukodystrophy Vanishing White Matter.

Dooves S, Leferink PS, Krabbenborg S, Breeuwsma N, Bots S, Hillen AEJ, Jacobs G, van der Knaap MS, Heine VM.

Stem Cell Reports. 2019 Mar 5;12(3):441-450. doi: 10.1016/j.stemcr.2019.01.018. Epub 2019 Feb 21.

2.

The catabolism of 3,3'-thiodipropionic acid in Variovorax paradoxus strain TBEA6: A proteomic analysis.

Heine V, Meinert-Berning C, Lück J, Mikowsky N, Voigt B, Riedel K, Steinbüchel A.

PLoS One. 2019 Feb 11;14(2):e0211876. doi: 10.1371/journal.pone.0211876. eCollection 2019.

3.

Neuron-Glia Interactions Increase Neuronal Phenotypes in Tuberous Sclerosis Complex Patient iPSC-Derived Models.

Nadadhur AG, Alsaqati M, Gasparotto L, Cornelissen-Steijger P, van Hugte E, Dooves S, Harwood AJ, Heine VM.

Stem Cell Reports. 2019 Jan 8;12(1):42-56. doi: 10.1016/j.stemcr.2018.11.019. Epub 2018 Dec 20.

4.

Generation of Isogenic Controls for In Vitro Disease Modelling of X-Chromosomal Disorders.

Hinz L, Hoekstra SD, Watanabe K, Posthuma D, Heine VM.

Stem Cell Rev. 2018 Nov 13. doi: 10.1007/s12015-018-9851-8. [Epub ahead of print]

PMID:
30421281
5.

Patterning factors during neural progenitor induction determine regional identity and differentiation potential in vitro.

Nadadhur AG, Leferink PS, Holmes D, Hinz L, Cornelissen-Steijger P, Gasparotto L, Heine VM.

Stem Cell Res. 2018 Oct;32:25-34. doi: 10.1016/j.scr.2018.08.017. Epub 2018 Aug 23.

6.

Axonal abnormalities in vanishing white matter.

Klok MD, Bugiani M, de Vries SI, Gerritsen W, Breur M, van der Sluis S, Heine VM, Kole MHP, Baron W, van der Knaap MS.

Ann Clin Transl Neurol. 2018 Mar 1;5(4):429-444. doi: 10.1002/acn3.540. eCollection 2018 Apr.

7.

Adult mouse eIF2Bε Arg191His astrocytes display a normal integrated stress response in vitro.

Wisse LE, Ter Braak TJ, van de Beek MC, van Berkel CGM, Wortel J, Heine VM, Proud CG, van der Knaap MS, Abbink TEM.

Sci Rep. 2018 Feb 28;8(1):3773. doi: 10.1038/s41598-018-21885-x.

8.

Why eavesdropping in open-plan spaces is good for your research.

Heine V.

Nature. 2017 Dec 21;552(7685):334. doi: 10.1038/d41586-017-08872-4. No abstract available.

PMID:
29293249
9.

Streamlined 3D Cerebellar Differentiation Protocol with Optional 2D Modification.

Holmes DB, Heine VM.

J Vis Exp. 2017 Dec 9;(130). doi: 10.3791/56888.

10.

Affected astrocytes in the spinal cord of the leukodystrophy vanishing white matter.

Leferink PS, Breeuwsma N, Bugiani M, van der Knaap MS, Heine VM.

Glia. 2018 Apr;66(4):862-873. doi: 10.1002/glia.23289. Epub 2017 Dec 29.

11.

The Healthy and Diseased Microenvironments Regulate Oligodendrocyte Properties: Implications for Regenerative Medicine.

Leferink PS, Heine VM.

Am J Pathol. 2018 Jan;188(1):39-52. doi: 10.1016/j.ajpath.2017.08.030. Epub 2017 Oct 10. Review.

PMID:
29024633
12.

Bergmann glia translocation: a new disease marker for vanishing white matter identifies therapeutic effects of Guanabenz treatment.

Dooves S, Bugiani M, Wisse LE, Abbink TEM, van der Knaap MS, Heine VM.

Neuropathol Appl Neurobiol. 2018 Jun;44(4):391-403. doi: 10.1111/nan.12411. Epub 2017 Aug 1.

PMID:
28953319
13.

Comparative gene expression study and pathway analysis of the human iris- and the retinal pigment epithelium.

Bennis A, Ten Brink JB, Moerland PD, Heine VM, Bergen AA.

PLoS One. 2017 Aug 21;12(8):e0182983. doi: 10.1371/journal.pone.0182983. eCollection 2017.

14.

Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium.

Bennis A, Jacobs JG, Catsburg LAE, Ten Brink JB, Koster C, Schlingemann RO, van Meurs J, Gorgels TGMF, Moerland PD, Heine VM, Bergen AA.

Stem Cell Rev. 2017 Oct;13(5):659-669. doi: 10.1007/s12015-017-9754-0.

15.

Genetically-Informed Patient Selection for iPSC Studies of Complex Diseases May Aid in Reducing Cellular Heterogeneity.

Hoekstra SD, Stringer S, Heine VM, Posthuma D.

Front Cell Neurosci. 2017 Jun 13;11:164. doi: 10.3389/fncel.2017.00164. eCollection 2017.

16.

Multi-level characterization of balanced inhibitory-excitatory cortical neuron network derived from human pluripotent stem cells.

Nadadhur AG, Emperador Melero J, Meijer M, Schut D, Jacobs G, Li KW, Hjorth JJJ, Meredith RM, Toonen RF, Van Kesteren RE, Smit AB, Verhage M, Heine VM.

PLoS One. 2017 Jun 6;12(6):e0178533. doi: 10.1371/journal.pone.0178533. eCollection 2017.

17.

Proteomic analysis of organic sulfur compound utilisation in Advenella mimigardefordensis strain DPN7T.

Meinert C, Brandt U, Heine V, Beyert J, Schmidl S, Wübbeler JH, Voigt B, Riedel K, Steinbüchel A.

PLoS One. 2017 Mar 30;12(3):e0174256. doi: 10.1371/journal.pone.0174256. eCollection 2017.

18.

Olig1 is required for noggin-induced neonatal myelin repair.

Sabo JK, Heine V, Silbereis JC, Schirmer L, Levison SW, Rowitch DH.

Ann Neurol. 2017 Apr;81(4):560-571. doi: 10.1002/ana.24907.

19.

Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons.

Emperador Melero J, Nadadhur AG, Schut D, Weering JV, Heine VM, Toonen RF, Verhage M.

Stem Cell Reports. 2017 Mar 14;8(3):659-672. doi: 10.1016/j.stemcr.2017.01.019. Epub 2017 Feb 23.

20.

Simplified 3D protocol capable of generating early cortical neuroepithelium.

Holmes DB, Heine VM.

Biol Open. 2017 Mar 15;6(3):402-406. doi: 10.1242/bio.021725.

21.

Leukodystrophies: Five new things.

van der Knaap MS, Wolf NI, Heine VM.

Neurol Clin Pract. 2016 Dec;6(6):506-514. doi: 10.1212/CPJ.0000000000000289.

22.

Modeling psychiatric disorders: from genomic findings to cellular phenotypes.

Falk A, Heine VM, Harwood AJ, Sullivan PF, Peitz M, Brüstle O, Shen S, Sun YM, Glover JC, Posthuma D, Djurovic S.

Mol Psychiatry. 2016 Sep;21(9):1321. doi: 10.1038/mp.2016.100. Epub 2016 Jun 21. No abstract available.

PMID:
27324182
23.

Modeling psychiatric disorders: from genomic findings to cellular phenotypes.

Falk A, Heine VM, Harwood AJ, Sullivan PF, Peitz M, Brüstle O, Shen S, Sun YM, Glover JC, Posthuma D, Djurovic S.

Mol Psychiatry. 2016 Sep;21(9):1167-79. doi: 10.1038/mp.2016.89. Epub 2016 May 31. Review. Erratum in: Mol Psychiatry. 2016 Sep;21(9):1321.

24.

Stem cell therapy for white matter disorders: don't forget the microenvironment!

Dooves S, van der Knaap MS, Heine VM.

J Inherit Metab Dis. 2016 Jul;39(4):513-8. doi: 10.1007/s10545-016-9925-1. Epub 2016 Mar 21.

25.

Astrocytes are central in the pathomechanisms of vanishing white matter.

Dooves S, Bugiani M, Postma NL, Polder E, Land N, Horan ST, van Deijk AL, van de Kreeke A, Jacobs G, Vuong C, Klooster J, Kamermans M, Wortel J, Loos M, Wisse LE, Scheper GC, Abbink TE, Heine VM, van der Knaap MS.

J Clin Invest. 2016 Apr 1;126(4):1512-24. doi: 10.1172/JCI83908. Epub 2016 Mar 14.

26.

Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration.

Bennis A, Gorgels TG, Ten Brink JB, van der Spek PJ, Bossers K, Heine VM, Bergen AA.

PLoS One. 2015 Oct 30;10(10):e0141597. doi: 10.1371/journal.pone.0141597. eCollection 2015.

27.

Detection of silent cells, synchronization and modulatory activity in developing cellular networks.

Hjorth JJ, Dawitz J, Kroon T, Pires J, Dassen VJ, Berkhout JA, Emperador Melero J, Nadadhur AG, Alevra M, Toonen RF, Heine VM, Mansvelder HD, Meredith RM.

Dev Neurobiol. 2016 Apr;76(4):357-74. doi: 10.1002/dneu.22319. Epub 2015 Jul 1.

28.

Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle.

Dubey M, Bugiani M, Ridder MC, Postma NL, Brouwers E, Polder E, Jacobs JG, Baayen JC, Klooster J, Kamermans M, Aardse R, de Kock CP, Dekker MP, van Weering JR, Heine VM, Abbink TE, Scheper GC, Boor I, Lodder JC, Mansvelder HD, van der Knaap MS.

Ann Neurol. 2015 Jan;77(1):114-31. doi: 10.1002/ana.24307. Epub 2014 Dec 4.

PMID:
25382142
29.

Human ciliary epithelia do express genes with retinal progenitor cell characteristics in vivo.

Janssen SF, Bennis A, Heine VM, Bergen AA.

Exp Eye Res. 2014 Apr;121:41. doi: 10.1016/j.exer.2014.01.020. Epub 2014 Feb 4. No abstract available.

PMID:
24508411
30.

Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain.

Silbereis JC, Nobuta H, Tsai HH, Heine VM, McKinsey GL, Meijer DH, Howard MA, Petryniak MA, Potter GB, Alberta JA, Baraban SC, Stiles CD, Rubenstein JL, Rowitch DH.

Neuron. 2014 Feb 5;81(3):574-87. doi: 10.1016/j.neuron.2013.11.024.

31.

A small-molecule smoothened agonist prevents glucocorticoid-induced neonatal cerebellar injury.

Heine VM, Griveau A, Chapin C, Ballard PL, Chen JK, Rowitch DH.

Sci Transl Med. 2011 Oct 19;3(105):105ra104. doi: 10.1126/scitranslmed.3002731.

32.

Some thoughts about Jürgen Hafner's work in computational materials science.

Heine V.

J Phys Condens Matter. 2011 Oct 12;23(40):400301. doi: 10.1088/0953-8984/23/40/400301. Epub 2011 Sep 19. No abstract available.

PMID:
21931188
33.

[Surviving the initial phase: subjective theories of illness in patients suffering from acute leukaemia at the end of initial inpatient treatment].

Koehler K, Dogan E, Koehler M, Heine V, Frommer J.

Z Psychosom Med Psychother. 2011;57(2):141-56. German.

PMID:
21626478
34.

Cerebellar abnormalities following hypoxia alone compared to hypoxic-ischemic forebrain injury in the developing rat brain.

Biran V, Heine VM, Verney C, Sheldon RA, Spadafora R, Vexler ZS, Rowitch DH, Ferriero DM.

Neurobiol Dis. 2011 Jan;41(1):138-46. doi: 10.1016/j.nbd.2010.09.001. Epub 2010 Sep 16.

35.

Conserved role of intragenic DNA methylation in regulating alternative promoters.

Maunakea AK, Nagarajan RP, Bilenky M, Ballinger TJ, D'Souza C, Fouse SD, Johnson BE, Hong C, Nielsen C, Zhao Y, Turecki G, Delaney A, Varhol R, Thiessen N, Shchors K, Heine VM, Rowitch DH, Xing X, Fiore C, Schillebeeckx M, Jones SJ, Haussler D, Marra MA, Hirst M, Wang T, Costello JF.

Nature. 2010 Jul 8;466(7303):253-7. doi: 10.1038/nature09165.

36.

Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma.

Heine VM, Priller M, Ling J, Rowitch DH, Schüller U.

Cancer Res. 2010 Jul 1;70(13):5220-5. doi: 10.1158/0008-5472.CAN-10-0554. Epub 2010 Jun 8.

37.

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade.

Hyman JM, Firestone AJ, Heine VM, Zhao Y, Ocasio CA, Han K, Sun M, Rack PG, Sinha S, Wu JJ, Solow-Cordero DE, Jiang J, Rowitch DH, Chen JK.

Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14132-7. doi: 10.1073/pnas.0907134106. Epub 2009 Aug 5.

38.

Hedgehog signaling has a protective effect in glucocorticoid-induced mouse neonatal brain injury through an 11betaHSD2-dependent mechanism.

Heine VM, Rowitch DH.

J Clin Invest. 2009 Feb;119(2):267-77. doi: 10.1172/JCI36376. Epub 2009 Jan 26.

39.

Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.

Schüller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL.

Cancer Cell. 2008 Aug 12;14(2):123-34. doi: 10.1016/j.ccr.2008.07.005.

40.

Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors.

Schüller U, Zhao Q, Godinho SA, Heine VM, Medema RH, Pellman D, Rowitch DH.

Mol Cell Biol. 2007 Dec;27(23):8259-70. Epub 2007 Sep 24.

41.

Brain drain: gains all round when it goes both ways.

Heine V.

Nature. 2007 May 3;447(7140):28. No abstract available.

PMID:
17476242
42.

Stress, depression and hippocampal apoptosis.

Lucassen PJ, Heine VM, Muller MB, van der Beek EM, Wiegant VM, De Kloet ER, Joels M, Fuchs E, Swaab DF, Czeh B.

CNS Neurol Disord Drug Targets. 2006 Oct;5(5):531-46. Review.

PMID:
17073656
43.

Effects of chronic stress on structure and cell function in rat hippocampus and hypothalamus.

Joëls M, Karst H, Alfarez D, Heine VM, Qin Y, van Riel E, Verkuyl M, Lucassen PJ, Krugers HJ.

Stress. 2004 Dec;7(4):221-31. Review.

PMID:
16019587
44.

Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk-1 protein expression.

Heine VM, Zareno J, Maslam S, Joëls M, Lucassen PJ.

Eur J Neurosci. 2005 Mar;21(5):1304-14.

PMID:
15813940
45.

Increased P27KIP1 protein expression in the dentate gyrus of chronically stressed rats indicates G1 arrest involvement.

Heine VM, Maslam S, Joëls M, Lucassen PJ.

Neuroscience. 2004;129(3):593-601.

PMID:
15541881
47.

Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible.

Heine VM, Maslam S, Zareno J, Joëls M, Lucassen PJ.

Eur J Neurosci. 2004 Jan;19(1):131-44.

PMID:
14750971
48.

Gene expression patterns in rat dentate granule cells: comparison between fresh and fixed tissue.

Qin Y, Heine VM, Karst H, Lucassen PJ, Joëls M.

J Neurosci Methods. 2003 Dec 30;131(1-2):205-11.

PMID:
14659840
49.

Crystal structure. As weird as they come

Heine V V.

Nature. 2000 Feb 24;403(6772):836-7. No abstract available.

PMID:
10706262
50.

Mechanism of tritium diffusion in lithium oxide.

Shah R, De Vita A, Heine V V, Payne MC.

Phys Rev B Condens Matter. 1996 Apr 1;53(13):8257-8261. No abstract available.

PMID:
9982322

Supplemental Content

Support Center